Human tyrosinase related protein-1 (TRP-1) does not function as a DHICA oxidase activity in contrast to murine TRP-1

Experimental Dermatology

Volumn 7, Issue 4, 1998, Pages 198-204

  Boissy, Raymond E ^a   Sakai, Chie ^b   Zhao, Huiquan ^a   Kobayashi, Takeshi ^b   Hearing, Vincent J ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Melanocyte; Pigmentation

Indexed keywords

MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASE; PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVITY; ENZYME ANALYSIS; EXPRESSION VECTOR; FIBROBLAST; HUMAN; HUMAN CELL; MELANOCYTE; MELANOGENESIS; MOUSE; NONHUMAN; OCULOCUTANEOUS ALBINISM;

EID: 0031690595     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.1998.tb00324.x     Document Type: Article

References (46)

1. Shibahara S, Tomita Y, Sakakura T, Nager C, Chaudhuri B, Muller R. Cloning and expression of cDNA encoding mouse tyrosinase. Nucleic Acids Res 1986: 14: 2413-2427.
2. Jackson I J. A cDNA encoding tyrosinase-related protein maps to the brown locus in mice. Proc Natl Acad Sci U S A 1988: 85: 4392-4396.
3. Hearing V J, Jiménez M. Analysis of mammalian pigmentation at the molecular level. Pigment Cell Res 1989: 2: 75-85.
4. Jackson I J, Chambers D M, Rinchik E M, Bennett D C. Characterization of TRP-1 mRNA levels in dominant and recessive mutations at the mouse brown (b) locus. Genetics 1990: 126: 451-459.
5. Abbott C, Jackson I J, Carritt B, Povey S. The human homolog of the mouse Brown gene maps to the short arm of chromosome 9 and extends the known region of homology with mouse chromosome 4. Genomics 1991: 11: 471-473.
6. Chintamaneni C D, Ramsay M, Colman M-A, Fox M F, Pickard R T, Kwon B S. Mapping the human CAS2 gene, the homologue of the mouse brown (b) locus, to human chromosome 9p22-pter. Biochem Biophys Res Commun 1991: 178: 227-235.
7. Murty V V, Bouchard B, Mathew S, Vijayasaradhi S, Houghton A N. Assignment of the human TYRP (brown) locus to chromosome region 9p23 by nonradioactive in situ hybridization. Genomics 1992: 13: 227-229.
8. Halaban R, Moellmann G E. Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity. Proc Natl Acad Sci U S A 1990: 87: 4809-4813.
9. Vijayasaradhi S, Doskoch P M, Houghton A N. Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (brown) locus product. Exp Cell Res 1991: 196: 233-240.
10. Orlow S J, Boissy R E, Moran D J, Pifko-Hirst S. Subcellular distribution of tyrosinase and tyrosinase-related protein-1: Implications for melanosomal biogenesis. J Invest Dermatol 1993: 100: 55-64.
11. Boissy R E, Zhao H, Getting W S et al. Mutation in and lack of expression of tyrosinase related protein-1 (TRP-1) in melanocytes from an individual with Brown oculocutaneous albinism: a new subtype of albinism classified as OCA3. Am J Hum Genet 1996: 58: 1145-1156.
12. Manga P, Kromberg J G R, Box N F, Sturm R A, Jenkins T, Ramsay M. Rufous oculocutaneous albinism in Southern African Blacks is caused by mutations in the TYRPI gene. Am J Hum Genet 1997: 61: 1095-1101.
13. Wang B R-F, Robbins P F, Kawakami Y, Kang X-Q, Rosenberg S A. Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. J Exp Med 1995: 181: 799-804.
14. Wolfel T, Van Pel A, Brichard V et al. Two tyrosinase non-apeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Eur J Immunol 1994: 24: 759-764.
15. Mattes M J, Thomson T M, Old L J, Lloyd K O. A pigmentation-associated differentiation antigen of human melanoma defined by a precipitating antibody in human serum. Int J Cancer 1983: 32: 717-721.
16. Hara I, Takechi Y, Houghton A N. Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus proteins. J Exp Med 1995: 182: 1609-1614.
17. Vijayasaradhi S, Bouchard B, Houghton A N. The melanoma antigen gp75 is the human homologue of the mouse b (brown) focus gene product. J Exp Med 1990: 171: 1375-1380.
18. Austin L M, Boissy R E, Jacobson B S, Smyth J R Jr. The detection of melanocyte autoantibodies in the Smyth chicken model for vitiligo. Clin Immunol Immunopathol 1992: 64: 112-120.
19. Austin L M, Boissy R E. Mammalian tyrosinase related protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. Am J Pathol 1995: 146: 1529-1541.
20. Jiménez M, Tsukamoto K, Hearing V J. Tyrosinases from two different loci are expressed by normal and by transformed melanocytes. J Biol Chem 1991: 266: 1147-1156.
21. Jiménez-Cervantes C, García-Borrón J C, Valverde P, Solano F, Lozano J A. Tyrosinase isoenzymes in mammalian melanocytes. I. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma. Eur J Biochem 1993: 217: 549-556.
22. Zhao H, Zhao Y, Nordlund J J, Boissy R E. Human TRP-1 has tyrosine hydroxylase activity but no dopa oxidase activity. Pigment Cell Res 1994: 7: 131-140.
23. Winder A J, Wittbjer A, Rosengren E, Rorsman H. The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts. J Cell Sci 1993: 106: 153-166.
24. Hearing V J. Unraveling the melanocyte. Am J Hum Genet 1993: 52: 1-7.
25. Jiménez-Cervantes C, Solano F, Kobayashi T et al. A new enzymatic function in the melanogenic pathway: the DHICA oxidase activity of tyrosinase related protein-1 (TRP1). J Biol Chem 1994: 269: 17993-18001.
26. Kobayashi T, Urabe K, Winder A J et al. Tyrosinase-related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. EMBO J 1994: 13: 5818-5825.
27. Cohen T, Müller R M, Tomita Y, Shibahara S. Nucleotide sequence of the cDNA encoding human tyrosinase-related protein. Nucleic Acids Res 1990: 18: 2807-2808.
28. Urquhart A. Human tyrosinase-like protein (TYRL) carboxy terminus: closer homology with the mouse protein than previously reported. Nucleic Acids Res 1991: 19: 5803.
29. Boissy R E, Liu Y-Y, Medrano E E, Nordlund J J. Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in long-term cultures of melanocytes from vitiligo patients. J Invest Dermatol 1991: 97: 395-404.
30. Zhao H, Eling D J, Medrano E E, Boissy R E. Retroviral infection with human tyrosinase related protein-1 (TRP-1) cDNA upregulates tyrosinase activity and melanin synthesis in a TRP-1 deficient melanoma cell line. J Invest Dermatol 1996: 106: 744-752.
31. Morgenstern J P, Land H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 1990: 18: 3587-3596.
32. Zhao H, Boissy Y, Abdel-Malek Z, King R A, Nordlund J J, Boissy R E. On the analysis of the pathophysiology of Chediak-Higashi syndrome: Defects expressed by cultured melanocytes. Lab Invest 1994: 71: 25-34.
33. Hearing V J. Mammalian monophenol monooxygenase (tyrosinase): Purification, properties, and reactions catalyzed. In: Kaufman S, ed. Methods in Enzymology - Metabolism of Aromatic Amino Acids and Amines. Vol. 142. New York: Academic Press, 1987: 154-165.
34. Aroca P, Urabe K, Kobayashi T, Tsukamoto K, Hearing V J. Melanin biosynthesis patterns following hormonal stimulation. J Biol Chem 1993: 268: 25650-25655.
35. Palumbo A, d'Ischia M, Misuraca G, Prota G. Effect of metal ions on the rearrangement of dopachrome. Biochim Biophys Acta 1987: 925: 203-209.
36. Kondoh H, Wilczek A, Narimizu S, Mishima Y. Mouse fibroblast expressing human tyrosinase with DHICA-oxidase activity produces predominantly pheomelanin deposit in lysosome. Zool Sci 1996: 13: 825-831.
37. Wilczek A, Kondoh H, Mishima Y. Composition of mammalian eumelanins: analyses of DHICA-derived units in pigments from hair and melanoma cells. Pigment Cell Res 1996: 9: 63-67.
38. Wilczek A, Mishima Y. Inhibitory effects of melanin monomers, dihydroxyindole-2-carboxylic acid (DHICA) and dihydroxyindole (DHI) on mammalian tyrosinase, with a special reference to the role of DHICA/DHI ratio in melanogenesis. Pigment Cell Res 1995: 8: 105-112.
39. Martinez-Esparza M, Jiménez-Cervantes C, García-Borrón J C et al. Comparison of TRPs from murine and human malignant melanocytes. Pigment Cell Res 1997: 10: 229-235.
40. Vijayasaradhi S, Xu Y, Bouchard B, Houghton A N. Intracellular sorting and targeting of melanosomal membrane proteins: Identification of signals for sorting of the human brown locus protein, GP75. J Cell Biol 1995: 130: 807-820.
41. Oetting W S, King R A. Analysis of tyrosinase mutations associated with tyrosinase-related oculocutaneous albinism (OCA1). Pigment Cell Res 1994: 7: 285-290.
42. Oetting W S, King R A. The molecular basis of oculocutaneous albinism. J Invest Dermatol 1994: 5: 131S-136S.
43. Tripathi R K, Strunk K M, Giebel L B, Weleber R G, Spritz R A. Tyrosinase gene mutations in Type I (tyrosinase-deficient) oculocutaneous albinism define two clusters of missense substitutions. Am J Med Genet 1992: 43: 865-871.
44. Tripathi R K, Hearing V J, Urabe K, Aroca P, Spritz R A. Mutational mappins of the catalytic activities of human tyrosinase. J Biol Chem 1992: 267: 23707-23712.
45. Jackson I J. Molecular and developmental genetics of mouse coat color. Annu Rev Genet 1994: 28: 189-217.
46. Sturm R A, O'Sullivan B J, Box N F et al. Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family. Genomics 1995: 29: 24-34.