Use of methotrexate in children

Bulletin on the Rheumatic Diseases

Volumn 47, Issue 5, 1998, Pages 1-5

  Passo, Murray H ^a   Hashkes, Philip J ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b Rebecca Sieff Government Hospital   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE;

CHILD; CHILDHOOD DISEASE; DERMATOMYOSITIS; DRUG INDUCED DISEASE; ENTERITIS; EYE INFLAMMATION; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; REVIEW; RHEUMATIC DISEASE; SARCOIDOSIS; TREATMENT INDICATION; VASCULITIS;

ADOLESCENT; ANTIRHEUMATIC AGENTS; ARTHRITIS, JUVENILE RHEUMATOID; CHILD; CHILD, PRESCHOOL; CLINICAL TRIALS; FEMALE; HUMANS; MALE; METHOTREXATE; PATIENT EDUCATION; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 0031690578     PISSN: 00075248     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (23)

1. Wallace CA: The use of methotrexate in childhood rheumatic diseases. Arthritis Rheum 41:381-391, 1998.
2. Singsen BH, Goldbach-Mansky R: Methotrexate in the treatment of juvenile rheumatoid arthritis and other pediatric rheumatic and nonrheumatic disorders. Rheum Dis Clin North Am 23:811-840, 1997.
3. Palier AS: Dermatologic uses of methotrexate in children: indications and guidelines. Pediatr Dermatol 2:238-243, 1985.
4. Cronstein BN, Merrill JT: Mechanisms of the effects of methotrexate. Bull Rheum Dis 45(5):6-8, 1996.
5. Giannini EH, Brewer EJ, Kuzima N, et al, for the Pediatric Rheumatology Collaborative Study Group and the Cooperative Children's Study Group: Methotrexate in resistant juvenile rheumatoid arthritis: results of the USA-USSR double-blind, placebo-controlled trial. N Engl J Med 326:1043-1049, 1992.
6. Mier R, Bowyer S, Lovell D, et al: Variations in medication choices in juvenile rheumatoid arthritis. J Clin Rheumatol 2:262-267, 1996.
7. Wallace CA, Sherry DD: Preliminary report of higher dose methotrexate treatment in juvenile rheumatoid arthritis. J Rheumatol 19:1604-1606, 1992.
8. Teresi ME, Crom WR, Cloi KE, Mirro J, Evans WE: Methotrexate bioavailability after oral and intramuscular administration in children. J Pediatr 110:788-792, 1987.
9. Harel L, Wagner-Weiner L, Poznanski AK, Spencer CH, Ekwo E, Magilavy DB: Effects of methotrexate on radiologic progression in juvenile rheumatoid arthritis. Arthritis Rheum 36:1370-1374, 1993.
10. Gottlieb BS, Keenan GF, Ilowite NT: Discontinuation of methotrexate treatment in juvenile rheumatoid arthritis. Pediatrics 100:994-997, 1997.
11. Shah SS, Lowder CY, Schmitt MA, Wilke WS, Kosmorsky GS, Meisler DM: Low-dose methotrexate therapy for ocular inflammatory disease. Ophthalmology 99(9):1419-1423, 1992.
12. Miller LC, Sisson BA, Tucker LB, DeNardo BA, Schaller JG: Methotrexate treatment of recalcitrant childhood dermatomyositis. Arthritis Rheum 35:1143-1149, 1992.
13. Gedalia A, Molina JF, Ellis GS, Galen W, Moore C, Espinoza LR: Low-dose methotrexate therapy for childhood sarcoidosis. J Pediatr 130:25-29, 1997.
14. Mack DR, Youn R, Kaufman SS, Ramey L, Vanderhoof JA: Methotrexate in patients with Crohn disease after 6-mercaptopurine. J Pediatr 132:850-856, 1998.
15. Gottlieb BS, Miller LC, Ilowite NT: Methotrexate treatment of Wegener granulomatosis in children. J Pediatr 129:604-607, 1996.
16. Hoffman GS, Leavitt RY, Kerr GS, Rottem M, Sneller MC, FauciAS: Treatment of glucocorticoid-resistant or relapsing Takayasu arteritis with methotrexate. Arthritis Rheum 37:578-582, 1994.
17. Hunt PG, Rose CD, McIlvain-Simpson G, Tejani S: The effects of daily intake of folic acid on the efficacy of methotrexate therapy in children with juvenile rheumatoid arthritis: a controlled study. J Rheumatol 24:2230-2232, 1997.
18. Hashkes PJ, Balistreri WF, Bove KE, Ballard ET, Passo MH: The long-term effect of methotrexate therapy on the liver in patients with juvenile rheumatoid arthritis. Arthritis Rheum 40:2226-2234, 1997.
19. Kremer JM, Alarcon GS, Lightfoot RW Jr, et al: Methotrexate for rheumatoid arthritis. Suggested guidelines for monitoring liver toxidty. Arthritis Rheum 37:316-328, 1994.
20. Cron RQ, Sherry DD, Wallace CA: Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis. J Pediatr 132:901-902, 1998.
21. Muzaffer MA, Schneider R, Cameron BJ, Silverman ED, Laxer RM: Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis. J Pediatr 128: 698-700, 1996.
22. Falcini F, Taccetti G, Ermini M, Trapani S, Calzolari A, Franchi A, et al: Methotrexate-associated appearance and rapid progression of rheumatoid nodules in systemic-onset juvenile rheumatoid arthritis. Arthritis Rheum 40:175-178, 1997.
23. Nash AA, Britto MT, Lovell DJ, Passo MH, Rosenthal SL: Substance use among adolescents with juvenile rheumatoid arthritis. Arthritis Care Res. In press.