In-vitro differentiation of mature dendritic cells from human blood monocytes

Developmental Immunology

Volumn 6, Issue 1-2, 1998, Pages 25-39

  Gieseler, Robert ^a,b   Heise, Dirk ^a   Soruri, Afsaneh ^a   Schwartz, Peter ^a   Peters, J Hinrich ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Dendritic cells; GM CSF; Interferon ; Interleukin 4; Macrophages; Mucosa

Indexed keywords

B7 ANTIGEN; CD1 ANTIGEN; CD11B ANTIGEN; CD14 ANTIGEN; CD16 ANTIGEN; CD18 ANTIGEN; CD32 ANTIGEN; CD33 ANTIGEN; CD40 ANTIGEN; CD45 ANTIGEN; CD64 ANTIGEN; CD68 ANTIGEN; CD71 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 3; INTERLEUKIN 4; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

CELL CULTURE; CELL DIFFERENTIATION; CELL STRUCTURE; CELLULAR IMMUNITY; CONFERENCE PAPER; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0031689596     PISSN: 10446672     EISSN: None     Source Type: Journal    
DOI: 10.1155/1998/72054     Document Type: Conference Paper

References (51)

1. Andreesen R., Osterholz J., Bodemann H., Bross K.J., Costabel U, and Lohr G.W. (1984). Expression of transferrin receptors and intracellular ferritin during terminal differentiation of human monocytes. Blood 49: 195-202.
2. Austyn J.M. (1987). Lymphoid dendritic cells. Immunology 62: 161-170.
3. Ardavin C., Wu L., Li C.-L., and Shortman K. (1993). Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature 362: 761-763.
4. Barfoot R., Denham S., Gyure L.A., Hall J.G., Hobbs S.M., Jackson L.E., and Robertson D. (1989). Some properties of dendritic macrophages from peripheral lymph. Immunology 68: 233-239.
5. Beelen R.H.J., Steenbergen J.J.E., van Vugt E., Betjes M.G.H., Havenith C.E.G., and Kamperdijk E.W.A. (1993). Dendritic cells isolated from rat and human non-lymphoid tissue are very potent accessory cells. Adv. Exp. Med. Biol. 329: 123-127.
6. Brooks C.F., and Moore M. (1988). Differential MHC class II expression on human peripheral blood monocytes and dendritic cells. Immunology 63: 303-311.
7. Chen-Woan M., Delaney C.P., Fournier V., Wakizaka Y., Murase N., Fung J., Starzl T.E., and Demetris A.J. (1996). In vitro characterization of rat bone marrow-derived dendritic cells and their precursors. J. Leukoc. Biol. 59: 196-207.
8. Everson M.P., McDuffie D.S., Lemak D.G., Koopman W.J., McGhee J.R., and Beagley K.W. (1996). Dendritic cells from different tissues induce production of different T cell cytokine profiles. J. Leukoc. Biol. 59: 494-498.
9. Franklin W.A., Mason D.Y., Pulford K., Falini B., Bliss E., Gatter K.C., Stein H., Clarke L.C., and McGee J.O. (1986). Immunohistological analysis of human mononuclear phagocytes and dendritic cells by using monoclonal antibodies. Lab. Invest. 54: 322-335.
10. Gieseler R.K.H. (1987). In vitro-Induktion von akzessorischen Immunzellen bei Maus, Ratte und Mensch. Ph.D. diss., Georg-August University, Göttingen.
11. + inflammatory macrophages generated in vitro: implications for ulcerative colitis and AIDS. Clin Exp. Immunol. (in press).
12. Gieseler R.K.H., Röber R.-A., Kuhn R., Weber K., Osborn M., and Peters J.H. (1991). Dendritic accessory cells derived from rat bone marrow precursors under chemically defined conditions in vitro belong to the myeloid lineage. Eur. J. Cell Biol. 54: 171-181.
13. Graeme-Cook F., Bhan A.K., and Harris N.L. (1993). Immunohistochemical characterization of intraepithelial and subepithelial mononuclear cells of the upper airways. Am. J. Pathol. 143: 1416-1422.
14. Inaba K., Inaba M., Deguchi M., Hagi K., Yasumizu R., Ikehara S., Muramatsu S., and Steinman R.M. (1993). Granulocytes, macrophages and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow. Proc. Nad. Acad. Sci. USA 90: 3038-3042.
15. Kabel P.J., De Haan-Meulmann M., Voorbij H.A.M., Kleingeld M., Knol E.F., and Drexhage H.A. (1989). Accessory cells with the morphology and marker pattern of dendritic cells can be obtained from elutriator-purified blood monocyte fractions: an enhancing effect of metrizamide in this differentiation. Immunobiology 179: 395-410.
16. + leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4. J. Leukoc. Biol. 59: 208-218.
17. Knight S.C., Farrant J., Bryant A., Edwards A.J., Burman S., Lever A., Clarke J., and Webster D.B. (1986). Nonaderent, low-density cells from human peripheral blood contain dendritic cells and monocytes, both with veiled morphology. Immunology 57: 595-603.
18. Lub M., van Kooyk Y., and Figdor C.G. (1996). Competition between lymphocyte function-associated antigen 1 (CD11a/ CD18) and Mac-1 (CD11b/CD18) for binding to intercellular adhesion molecule-1 (CD54). J. Leukoc. Biol. 59: 648-655.
19. McLellan A.D., Starling G.C., Williams L.A., Hock B.D., and Hart D.N.J. (1995). Activation of human peripheral blood dendritic cells induces the CD86 costimulatory molecule. Eur. J. Immunol. 25: 2064-2068.
20. Najar H.M., Bru-Capdeville A.C., Gieseler R.K.H., and Peters J.H. (1990). Differentiation of human monocytes into accessory cells at serum-free conditions. Eur. J. Cell Biol. 51: 339-346.
21. O'Doherty U., Peng M., Gezelter S., Swiggard W.J., Betjes M., Bhardwaj N., and Steinman R.M. (1994). Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. Immunology 82: 487-493.
22. O'Doherty U., Steinman R.M., Peng M., Cameron P.U., Gezelter S., Kopeloff I., Swiggard W.J., Pope M., and Bhardwaj N. (1993). Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. J. Exp. Med. 178: 1067-1076.
23. O'Neill H.C. (1994). The lineage relationship of dendritic cells with other haematopoietic cells. Scand. J. Immunol. 39: 513-516.
24. Pavli P., Hume D.A., van de Pol E., and Doe W.F. (1993). Dendritic cells, the major antigen-presenting cells of the human colonie mucosa. Immunology 78: 132-141.
25. Peters J.H., Gieseler R., Thiele B., and Steinbach F. (1996). Dendritic cells: from ontogenetic orphans to myelomonocytic descendants. Immunol. Today 17: 273-278.
26. Peters J.H., Ruhl S., and Friedrichs D. (1987). Veiled accessory cells deduced from monocytes. Immunobiology 176: 154-166.
27. Peters J.H., Ruppert J., Gieseler R.K.H., Najar H.M., and Xu H. (1991). Differentiation of human monocytes into CD14 negative accessory cells: Do dendritic cells derive from the monocytic lineage? Pathobiology 59: 122-126.
28. - T lymphocytes to a microbial antigen. Nature 360: 593-597.
29. Rastellini C., Lu L., Ricordi C., Starzl T.E., Rao A.S. and Thomson A.W. (1995). Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival. Transplantation 60: 1366-1370.
30. + progenitors in human bone marrow. Immunology 149: 2681-2688.
31. Reis e Sousa C., Stahl P., and Austyn J. (1993). Phagocytosis of antigens by Langerhans cells in vitro. J. Exp. Med. 178: 509-519.
32. Robinson A.P., White T.M., and Mason D.W. (1986). Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57: 239-247.
33. Rock K.L., Rothstein L., Gamble S., and Fleischacker C. (1993). Characterization of antigen-presenting cells that present exogenous antigens in association with class 1 MHC molecules. J. Immunol. 150: 438-446.
34. Romani N., Gruner S., Brang D., Kämpgen E., Lenz A., Trockenbacher B., Kowalinka G., Fritsch P.O., Steinman R.M., and Schuler G. (1994). Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180: 83-93.
35. Ruppert J., Schütt C., Ostermeier D., and Peters J.H. (1993). Down-regulation and release of CD14 on human monocytes by IL-4 depends on the presence of serum or GM-CSF. Adv. Exp. Med. Biol. 329: 281-286.
36. Sallusto F., and Lanzavecchia A. (1994). Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 179: 1109-1118.
37. Santiago-Schwarz F., Belilos E., Diamond B. and Carsons S.E. (1992). TNF in combination with GM-CSF enhances the differentiation of neonatal cord blood stem cells into dendritic cells and macrophages. J. Leukoc. Biol. 52: 274-281.
38. Soruri A., Fayyazi A., Gieseler R., Schlott T., Rünger T.M., Neumann C., and Peters J.H. (1998). Specific autologous antimelanoma T cell response in vitro using monocyte-derived dendritic cells. Immunobiology 198: 39-50.
39. Starling G.C., McLellan A.D., Egner W., Sorg R.V., Fawcett J., Simmons D.L., and Hart D.N.J. (1995). Intercellular adhesion molecule-3 is the predominant costimulatory ligand for leukocyte function antigen-1 on human blood dendritic cells. Eur. J. Immunol. 25: 2528-2532.
40. Steinbach F., Krause B., and Thiele B. (1995). Monocyte-derived cells (MoDC) represent phenotype and functional activities of Langerhans cells/dendritic cells. Adv. Exp. Med. Biol. 378: 151-153.
41. Steinman R.M. (1991). The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9: 271-296.
42. Steinman R.M., and Cohn Z. (1973). Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation and tissue distribution. J. Exp. Med. 137: 1142-1162.
43. Thomas R., Davis L.S., and Lipsky P.E. (1993). Isolation and characterization of human peripheral blood dendritic cells. J. Immunol. 150: 821-834.
44. Thomas R. and Lipsky P.E. (1994). Human peripheral blood dendritic cell subsets: isolation and characterization of precursor and mature antigen-presenting cells. J. Immunol. 153: 4016-4072.
45. Thompson C.B. (1995). Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 81: 979-982.
46. Werfel T., Sonntag G., Weber M.H., and Götze O. (1991). Rapid increases in the membrane expression of neutral endopeptidase (CD10), aminopeptidase N (CD13), tyrosine phosphatase (CD45), and FcγRIII (CD16) upon stimulation of human peripheral leucocytes with human C5a. J. Immunol. 147: 3909-3914.
47. Witmer-Pack M., Olivier W., Valinsky J., Schuler G., and Steinman R. (1987). Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells. J. Exp. Med. 166: 1484-1489.
48. Xu H., Krämer M., Spengler H.-P., and Peters J.H. (1995). Dendritic cells differentiated from human monocytes through a combination of IL-4, GM-CSF and IFN-γ exhibit phenotype and function of blood dendritic cells. Adv. Exp. Med. Biol. 378: 75-78.
49. Yamamoto M., Fujihashi K., Beagley K.W., McGhee J.R., and Kiyono H. (1993). Cytokine synthesis by intestinal intraepithelial lymphocytes. Both γ/δ T cell receptor-positive and α/β T cell receptor-positive T cells in the G1 phase of cell cycle produce IFN-γ and IL-5. J. Immunol. 150: 106-114.
50. Zhou L.-J., and Tedder T.F. (1995). Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J. Immunol. 154: 3821-3835.
51. + dendritic cells. Proc. Natl. Acad. Sci. USA 93: 2588-2592.