Lymphoblastoid interferon-α downregulates parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor expression in human osteoblastic cells (Saos-2)

Bone

Volumn 23, Issue 3, 1998, Pages 205-211

  Tsuda Futami, E ^a   Shioi, Atsushi ^a   Jono, S ^a   Inaba, M ^a   Nishizawa, Y ^a   Morii, H ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone gla protein; Bone sialoprotein; Interferon ; Osteoblast; Parathyroid hormone (PTH) PTH related peptide (PTHrP) receptor

Indexed keywords

ALKALINE PHOSPHATASE; ALPHA INTERFERON; CYCLIC AMP; DACTINOMYCIN; LYMPHOBLAST INTERFERON; MESSENGER RNA; OSTEOCALCIN; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN; PROSTAGLANDIN E2; RECEPTOR; SIALOPROTEIN;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; GENE EXPRESSION; HUMAN; OSTEOBLAST; RECEPTOR DENSITY;

ALKALINE PHOSPHATASE; CYCLIC AMP; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HUMANS; INTERFERON-ALPHA; OSTEOBLASTS; OSTEOCALCIN; RECEPTOR, PARATHYROID HORMONE, TYPE 1; RECEPTORS, PARATHYROID HORMONE; RNA, MESSENGER; SIALOGLYCOPROTEINS; TERIPARATIDE;

EID: 0031687795     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(98)00094-5     Document Type: Article

References (37)

1. Avvisati, G., Petrucci, M. T., and Mandelli, F. The role of biotherapies (interleukins, interferons and erythropoietin) in multiple myeloma. Balliere's Clin Haematol 8:815-829; 1995.
2. Beresford, J. N., Taylor, G. T., and Triffitt, J. T. Interferons and bones. Eur J Biochem 193:589-597; 1990.
3. Bos, M. P., van der Meer, J. M., Feyen, J. H., and Herrmann-Erlee, M. P. Expression of the parathyroid hormone receptor and correlation with other osteoblastic parameters in fetal rat osteoblasts. Calcif Tissue Int 58:95-100; 1996.
4. Conti, L., Hiscott, J., Papacchini, M., Roulston, A., Wainberg, M. A., Belardelli, F., and Gessani, S. Induction of rel(p65) and I kappa B alpha subunit expression during differentiation of human peripheral blood monocytes to macrophages. Cell Growth Diff 8:435-442; 1997.
5. Cortes, J. E., Talpaz, M., and Kantarjian, H. Chronic myelogenous leukemia: A review. Am J Med 100:555-570; 1996.
6. Ezaki, K., Hirano, M., Ohno, R., Yamada, K., Naito, K., Hirota, Y., Shirakawa, S., and Kimura, K. A combination of human lymphoblastoid Interferon and bestrabucil (KM2210) for adult T-cell leukemia-lymphoma. Cancer 68:695-698; 1991.
7. Forster, S., Triffitt, J. T., Bauer, H. C., Brosjo, O., Nilsson, O. S., Smith, R., and Sykes, B. Interferon-inhibited human osteosarcoma xenografts induce host bone in nude mice. J Bone Miner Res 3:199-202; 1988.
8. Fukayama, S., Tashjian, A. H. J., and Bringhurst, F. R. Mechanisms of desensitization to parathyroid hormone in human osteoblast-like SaOS-2 cells. Endocrinology 131:1757-1769; 1992.
9. Fukayama, S., Schipani, E., Jüppner, H., Lanske, B., Kronenberg, H. M., Abou-Samra, A-B., and Bringhurst, F. R. Role of protein kinase-A in homologous down-regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid in human osteoblast-like SaOS-2 cells. Endocrinology 134:1851-1858; 1994.
10. Futami, E., Shioi, A., Jono, S., Inaba, M., Nishizawa, Y., and Morii, H. Interferon-α can modulate the expression of parathyroid hormone receptor in human osteoblast-like cells. J Bone Miner Res 10(Suppl.):S173; 1995.
11. Gollner, G., Aman, M. J., Steffens, H. P., Huber, C., Peschel, C., and Derigs, H. G. Interferon-α (IFN-α) inhibits granulocyte-macrophage colony-stimulating factor (GM-CSF) expression at the post-transcriptional level in murine bone marrow stromal cells. Br J Haematol 91:8-14; 1995.
12. Gonzalez, E. A. and Martin, K. J. Coordinate regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells. Kidney Int 50:63-70; 1996.
13. Hoofnagle, J. H. and di Bisceglie, A. M. The treatment of chronic viral hepatitis. N Engl J Med 336:347-356; 1997.
14. Horowitz, M. C., Fields, A., DeMeo, D., Qian, H-Y., Bothwell, A. L. M., and Trepman, E. Expression and regulation of Ly-6 differentiation antigens by murine osteoblasts. Endocrinology 135:1032-1043; 1994.
15. Jilka, R. L. and Hamilton, J. W. Inhibition of parathormone-stimulated bone resorption by type I Interferon. Biochem Biophys Res Commun 120:553-558; 1984.
16. Jongen, J. W. J. M., Willemstein-van Hove, E. C., van der Meer, J. M., Bos, M. P., Jüppner, H., Segre, G. V., Abou-Samra, A-B., Feyen, J. H. M., and Herrmann-Erlee, M. P. M. Down-regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by transforming growth factor-β in primary fetal rat osteoblasts. Endocrinology 136:3260-3266; 1995.
17. Jüppner, H., Abou-Samra, A-B., Freeman, M., Kong, X. F., Schipani, E., Richards, J., Kolakowski, L. F., Jr., Hock, J., Potts, J. T., Jr., Kronenberg, H. M., and Segre, G. V. A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science 254:1024-1026; 1991.
18. Katz, M. S., Gutierrez, G. E., Mundy, G. R., Hymer, T. K., Caulfield, M. P., and McKee, R. L. Tumor necrosis factor and interleukin 1 inhibit parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by down-regulating parathyroid hormone receptors. J Cell Physiol 153:206-213; 1992.
19. Kurihara, N. and Roodman, G. D. Interferons-alpha and -gamma inhibit interleukin-1beta-stimulated osteoclast-like cell formation in long-term human marrow cultures. J Interferon Res 10:541-547; 1990.
20. Lehmann, T., Beyeler, C., Lammle, B., Hunziker, T., Vock, P., Olah, A. J., Dahinden, C., and Gerber, N. J. Severe osteoporosis due to systemic mast cell disease: Successful treatment with Interferon alpha-2B. Br J Rheumatol 35:898-900; 1996.
21. Liebhaber, S. A. mRNA stability and the control of gene expression. Nucl Acids Symp Ser 36:29-32; 1997.
22. McQuillan, D. J., Richardson, M. D., and Bateman, J. F. Matrix deposition by a calcifying human osteogenic sarcoma cell line (SAOS-2). Bone 16:415-426; 1995.
23. Miki, T., Yoshida, H., Shioi, A., Jono, S., Yoshino, M., Nakatsuka, K., Hagiwara, S., Kawagishi, T., Nishizawa, Y., and Morii, H. Effect of Interferon α on calcium and bone metabolism in patients with chronic hepatitis. J Bone Miner Metab 11:39-44; 1993.
24. Montserrat, E. and Hallek, M. Current strategies for the treatment of CLL. Leuk Lymphoma 22(Suppl. 2):65-68; 1996.
25. O'Brien, S., Kantarjian, H., and Talpaz, M. Practical guidelines for the management of chronic myelogenous leukemia with Interferon alpha. Leuk Lymphoma 23:247-252; 1996.
26. Peest, D., Blade, J., Harousseau, J. K., Klein, B., Osterborg, A., and San Miguel, J. F. Cytokine therapy in multuple myeloma. Br J Haematol 94:425-432; 1996.
27. Petska, S., Langer, J. A., Zoon, K. C., and Samuel, C. E. Interferons and their actions. Annu Rev Biochem 56:727-777; 1987.
28. Savage, P. D. Renal cell carcinoma. Curr Opin Oncol 8:247-251; 1996.
29. Schneider, H-G., Allan, E. H., Moseley, J. M., Martin, T. J., and Findlay, D. M. Specific down-regulation of parathyroid hormone (PTH) receptors and responses to PTH by tumor necrosis factor a and retinoic acid in UMR 106-06 osteoblast-like osteosarcoma cells. Biochem J 280:451-457; 1991.
30. Schneider, H. G., Michelangeli, V. P., Frampton, R. J., Grogan, J. L., Ikeda, K., Martin, T. J., and Findlay, D. M. Transforming growth factor-beta modulates receptor binding of calciotropic hormones and G protein-mediated adenylate cyclase responses in osteoblast-like cells. Endocrinology 131:1383-1389; 1992.
31. Segre, G. V. Receptors for parathyroid hormone and parathyroid hormone-related protein. In: Bilezikian, J. P., Marcus, R., and Levine, M. A., Eds. The Parathyroids: Basic and Clinical Concepts. New York: Raven; 1994; 213-229.
32. Titus, L., Jackson, E., Nanes, M. S., Rubin, J. E., and Catherwood, B. D. 1,25-Dihydroxyvitamin D reduces parathyroid hormone receptor number in ROS 17/2.8 cells and prevents the glucocorticoid-induced increase in these receptors: Relationship to adenylate cyclase activation. J Bone Miner Res 6:631-637; 1991.
33. Weide, R., Ehlenz, K., Lorenz, W., Walthers, E., Klausmann, M., and Pfluger, K. H. Successful treatment of osteoporosis in systemic mastocytosis with interferon alpha-2b. Ann Hematol 72:41-43; 1996.
34. Woo, M. H. and Burnakis, T. G. Interferon alfa in the treatment of chronic viral hepatitis B and C. Ann Pharmacother 31:330-337; 1997.
35. Yamaguchi, D. T., Green, J., Kleeman, C. R., and Muallem, S. Prostaglandins enhance parathyroid hormone-evoked increase in free cytosolic calcium concentration in osteoblast-like cells. Cell Calcium 12:609-622; 1991.
36. Yamamoto, I., Potts, J. T. J., and Segre, G. V. Glucocorticoids increase parathyroid hormone receptors in rat osteoblastic osteosarcoma cells (ROS 17/2). J Bone Miner Res 6:707-712; 1988.
37. Zhou, A., Hassel, B. A., and Silverman, R. H. Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of Interferon action. Cell 72:753-765; 1993.