Acoustic startle, prepulse inhibition, locomotion, and latent inhibition in the neuroleptic responsive (NR) and neuroleptio-nonresponsive (NNR) lines of mice

Psychopharmacology

Volumn 139, Issue 4, 1998, Pages 322-331

  Kline, Lori ^a,b   Decena, Eric ^a,b   Hitzemann, Robert ^a,b   McCaughran Jr , James ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acoustic startle response; Latent inhibition; Locomotion; Neuroleptic induced catalepsy; Prepulse inhibition; Schizophrenia; Selected mouse lines

Indexed keywords

NEUROLEPTIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; DRUG SENSITIVITY; LATENT INHIBITION; LOCOMOTION; MOUSE; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; STARTLE REFLEX;

ACOUSTIC STIMULATION; ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; CATALEPSY; MALE; MICE; MICE, INBRED STRAINS; MOTOR ACTIVITY; SCHIZOPHRENIC PSYCHOLOGY; STARTLE REACTION;

EID: 0031687527     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050723     Document Type: Article

References (67)

1. Anscomhe R (1987) the disorder of consciousness in schizophrenia. Schizophr Bull 13:241-260
2. Barrett RJ, Leith NJ, Ray OS (1973) A behavioral and pharmacological analysis of variables mediating active-avoidance behavior in rats. J Comp Physiol Psychol 82:489-500
3. Baruch I, Hemsley DR, Gray JA (1988) Differential performance of acute and chronic schizophrenics in a latent inhibition task. J Nerv Ment Dis 176:598-606
4. Bianchi C, Marazzi-Uberti E (1969) Acquisition and retention of a conditioned avoidance response in mice as influenced by pemoline, by some of its derivative and by some CNS stimulants. Psychopharmacologia 15:9-18
5. Braff DL (1993) Information processing and attention dysfunctions in schizophrenia. Schizophr Bull 19:233-259
6. Braff DL, Geyer MA (1990) Sensorimotor gating and schizophrenia: Human and animal model studies. Arch Gen Psychiatry 47:181-180
7. Braff DL, Grillon C, Geyer MA (1992) Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry 49:206-215
8. Bullock AE, Slobe BS, Vazquez V, Collins AC (1997) Inbred mouse strains differ in the regulation of startle and prepulse inhibition of the startle response. Behav Neurosci 111:1353-1360
9. Carlson S, Willott JR (1996) The behavioral salience of tones as indicated by prepulse inhibition of the startle response: relationship to hearing loss and central neural plasticity in C57BL/6J mice. Hearing Res 99:168-175
10. Castellanos FX, Fine EJ, Kozuch PL, et al. (1993) Sensorimotor gating in boys with Tourette's syndrome and attention deficit hyperactivity disorder. Soc Neurosci Abstr 19:991
11. Christison GW, Atwater GE, Dunn LA, Kilts CD (1988) Haloperidol enhancement of latent inhibition: relation to therapeutic action. Biol Psychiatry 23:746-749
12. 2 dopamine receptors. MS Dissertation, SUNY at Stony Brook. Department of Pharmacology
13. Crawley JN, Belknap JK, Collins A, Crabbe JC, Frankel W, Henderson N, Hitzemann RJ, Maxson SC, Miner LL, Silva AJ, Wehner JM, Wynshaw-Boris A, Paylor R (1997) Behavioral phenotypes of inbred mouse strains. Psychopharmacology 132: 107-124
14. Dains K, Hitzemann B, Hitzemann R (1996) Genetics, neuroleptic response and the organization of the cholinergic neurons in the mouse striatum. J Pharmacol Exp Ther 279:1430-1438
15. Depoortere R, Perrault G, Sanger DJ (1997) Potentiation of prepulse inhibition of the startle reflex in rats: pharmacological evaluation of the procedure as a model for detecting antipsychotic activity. Psychopharmacology 132:366-374
16. Deutch A, Lee M, Iasarola M (1992) Regionally specific effects of atypical anitipsychotic drugs in striatal Fos expression: the nucleus accumbens shell as a locus of antipsychotic action. Mol Cell Neurosci 3:332-341
17. 2 dopamine receptor antagonists induce fos and related proteins in rat striatal neurons. Neuroscience 37:287-294
18. Dulawa SC, Hen R, Scearce-Levie K, Geyer MA (1997) Serotonin 1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin 1B knockout mice. Psychopharmacology 132:125-134
19. Dunn LA, Atwater GE, Kilts CD (1993) Effects of antipsychotic drugs on latent inhibition: sensitivity and specificity of an animal behavioral model of clinical drug action. Psychopharmacology 112:315-323
20. Ellenbroek BA, Geyer MA, Cools AR (1995) The behavior of APO-SUS rats in animal models with construct validity for schizophrenia. J Neurosci 15:7604-7611
21. Feldon J, Weiner I (1991) The latent inhibition model of schizophrenic attention disorder. Haloperidol and sulpiride enhance rats ability to ignore irrelevant stimuli. Biol Psychiatry 29: 635-646
22. Gray JA, Feldon J, Rawlins JN, Hemsley DR, Smith AD (1991) The neuropsychology of schizophrenia. Behav Brain Sci 14: 1-84
23. Henry KR (1983) Ageing and audition. In: Willott JR (ed) Auditory psychobiology of the mouse. Thomas, Springfield Ill., pp 470-493
24. Hitzemann RJ, Dains K, Bur-Langing CM, Zahniser NR (1991) Selection of the haloperidol responsive and haloperidol non-responsive lines of mice. Psychopharmacology 103:244-250
25. Hitzemann RJ, Hitzemann B, Dains K, Qian Y, Kanes S (1993) Dopamine and acetylcholine cell density in the neuroleptic responsive (NR) and neuroleptic non-responsive (NNR) lines of mice. J Pharmacol Exp Ther 266:431-438
26. Hitzemann B, Dains K, Kanes S, Hitzemann R (1994) Further studies on the relationship between dopamine cell density and haloperidol-induced catalepsy. J Pharmacol Exp Ther 271: 969-976
27. Hitzemann R, Hitzemann B, Kanes S, Dains K (1995) Genetics and organization of the basal ganglia. Int Rev Neurobiol 38:43-94
28. Hoffman DC, Donovan H (1994) D-1 and D-2 receptor antagonists reverse pre-pulse inhibition deficits in an animal model of schizophrenia. Psychopharmacology 115:447-453
29. Hoffman HS, Ison JR (1980) Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input. Psychol Rev 87:175-189
30. Humby T, Wilkinson LS, Robbins TW, Geyer MA (1996) Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat. J Neurosci 16:2149-2156
31. Kaas JH (1991) Plasticity of sensory and motor maps in adult mammals. Annu Rev Neurosci 14:137-167
32. Kanes S, Hitzemann B, Hitzemann R (1993) On the relationships between dopamine receptor density and haloperidol-induced catalepsy among eight inbred mouse strains. J Pharmacol Exp Ther 267:538-545
33. Kanes S, Hitzemann B, Hitzemann R (1996) Mapping the genes for haloperidol-induced catalepsy. J Pharmacol Exp Ther 277: 1016-1025
34. Killcross AS, Robbins TW (1993) Differential effects of intra-accumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm. Psychopharmacology 188:101-103
35. Killcross AS, Dickinson A, Robbins TW (1994) Amphetamine-induced disruptions of latent inhibition are reinforcer mediated: implications for animal models of schizophrenic attentional dysfunction. Psychopharmacology 115:185-195
36. Kodsi MH, Swerdlow NR (1994) Quinolinic acid lesions of the ventral striatum reduce sensorimotor gating of acoustic startle in rats. Brain Res 643:59-65
37. Kodsi MH, Swerdlow NR (1995) Prepulse inhibition in the rat is regulated by ventral and caudodorsal striato-pallidal circuitry. Behav Neurosci 109:912-928
38. 1 hybrids: implications of genetic background for single gene and quantitative trait loci analyses. Neuroscience 80: 1075-1086
39. Lubow RE, Gewirtz JC (1995) Latent inhibition in humans: data, theory, and implications for schizophrenia. Psychol Bull 117: 87-103
40. Lubow RH, Weiner I, Feldon J (1982) An animal model of attention. In: Spiegelstein MY, Levy A (eds) Behavioral models and the analysis of drug action. Elsevier, Amsterdam, pp 87-107
41. Lubow RE, Weiner I, Schlossberg A, Baruch I (1987) Latent inhibition and schizophrenia. Bull Psychon Soc 25:464-467
42. McCaughran JA Jr, Mahjubi E, Decena E, Hitzemann R (1997) Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition. Psychopharmacology 134:131-140
43. Mansbach RS, Geyer MA, Braff DL (1988) Dopaminergic stimulation disrupts sensorimotor gating in the rat. Psychopharmacology 94:507-514
44. Marks MJ, Sitzel JA, Collins AC (1989) Genetic influences on nicotine responses. Pharmacol Biochem Behav 33:667-678
45. Ornitz EM, Lane SJ, Sugiyama T, de Traversay J (1992) Prestimulation-induced startle modulation in attention deficit hyperactivity disorder and nocturnal enuresis. Psychophysiology 29:437-451
46. Parham K, Willott JF (1988) The acoustic startle response in young and aging C57BL/6J and CBA/J mice. Behav Neurosci 104: 831-840
47. Patel N, Hitzemann B, Hitzemann R (1998) Genetics, haloperidol and the Fos response in the basal ganglia: a comparison of the C57BL/6J and DBA/2J inbred mouse strains. Neuropsychopharmacology (in press)
48. Paylor R, Crawley JN (1997) Inbred strain differences in prepulse inhibition of the mouse startle response. Psychopharmacology 132:169-180
49. 2 dopamine receptor distribution in the neuroleptic nonresponsive and neuroleptic responsive lines of mice, a quantitative receptor autoradiographic study. J Pharmacol Exp Ther 261:341-348
50. 2 mRNA levels in the neuroleptic-responsive (NR) and the neuroleptic non-responsive (NNR) lines of mice. J Pharmacol Exp Ther 267:1582-1590
51. Rasmussen E, Cipp L, Patel V, Mahjubi, E, Hitzemann R (1997) Haloperidol-induced catalepsy does not map to Drd2 in a BALB/c x LP cross. Soc Neurosci 23:722.2
52. Robertson GS, Matsumura H, Fibiger HC (1994) Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity. J Pharmacol Exp Ther 271:1058-1066
53. Salvi RJ, Henderson D, Fiorino F, Colleti V (1996) Auditory system plasticity and regeneration. Thieme, New York
54. Schwarzkopf SB, Bruno JP, Mitra T (1993) Effects of haloperidol and SCH 23390 on acoustic startle and prepulse inhibition under basal and stimulated conditions. Prog Neuro-Psychopharmacol Biol Psychiatry 17: 1023-1036
55. Swerdlow NR, Braff DL, Masten VL, Geyer MA (1990) Schizophrenic-like sensorimotor gating abnormalities in rats following dopamine infusion into the nucleus accumbens. Psychopharmacology 101:414-420
56. Swerdlow NR, Keith VA, Braff DL, Geyer MA (1991) The effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine-inhibition of sensorimotor gating of the startle response in the rat. J Pharmacol Exp Ther 256:530-536
57. Swerdlow NR, Braff DL, Taaid N, Geyer MA (1994) Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry 51:139-154
58. Swerdlow NR, Fillon D, Geyer MA, Braff DL (1995) Normal personality correlates of cognitive, visuo-spatial and sensorimotor gating. Biol Psychiatry 37:286-299
59. Trune DR, Kempton JB, Mitchell C (1996) Auditory function in the C3H/HeJ and C3H/HeSnJ mouse strains. Hearing Res 96:41-45
60. Wan FJ, Swerdlow NR (1993) Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats. Psychopharmacology 113:103-109
61. Wan FJ, Geyer MA, Swerdlow NR (1995) Presynaptic dopamine-glutamate interactions in the nucleus accumbens regulate sensorimotor gating. Psychopharmacology 120:433-441
62. 2 interactions regulate prepulse inhibition in rats? Neuropsychopharmacology 14:265-274
63. Weiner I, Feldon J (1987) Facilitation of latent inhibition by haloperidol in rats. Psychopharmacology 91:248-253
64. Weiner I, Lubow RE, Feldon J (1984) Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats. Psychopharmacology 83:194-199
65. Weiner I, Lubow RE, Feldon J (1988) Disruption of latent inhibition by acute administration of low doses of amphetamine. Pharmacol Biochem Behav 30:871-878
66. Willott JF, Carlson S, Chen H (1994) Prepulse inhibition of the startle response in mice: relationship to hearing loss and auditory system plasticity. Behav Neurosci 108:703-713
67. Young AMJ, Joseph MH, Gray JA (1993) Latent inhibition of conditioned dopamine release in rat nucleus accumbens. Neuroscience 54:5-9