Evening administration of melatonin and bright light: Interactions on the EEG during sleep and wakefulness

Journal of Sleep Research

Volumn 7, Issue 3, 1998, Pages 145-157

  Cajochen, Christian ^a,b   Kräuchi, Kurt ^a   Danilenko, Konstantin V ^a,c   Wirz Justice, Anna ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c INSTITUTE OF PHYSIOLOGY   (Russian Federation)

Author keywords

Acute and phase shifting effects; Circadian rhythms; EEG spectral analysis; Sleep quality; Sleepiness

Indexed keywords

MELATONIN;

ADULT; ALPHA RHYTHM; ARTICLE; CIRCADIAN RHYTHM; ELECTROENCEPHALOGRAM; HUMAN; HUMAN EXPERIMENT; LIGHT; MALE; NONREM SLEEP; NORMAL HUMAN; PRIORITY JOURNAL; REM SLEEP; SLOW BRAIN WAVE; SLOW WAVE SLEEP; SOMNOLENCE; THETA RHYTHM; WAKEFULNESS;

ADULT; CIRCADIAN RHYTHM; CROSS-OVER STUDIES; ELECTROENCEPHALOGRAPHY; FREE RADICAL SCAVENGERS; HUMANS; LIGHT; MALE; MELATONIN; SLEEP, REM; WAKEFULNESS;

EID: 0031687046     PISSN: 09621105     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2869.1998.00106.x     Document Type: Article

References (43)

1. Achermann, P. and Borbely, A. A. Dynamics of EEG slow wave activity during physiological sleep and after administration of benzodiazepine hypnotics. Hum. Neurobiol., 1987, 6: 203-210.
2. Attenburrow, M.E.J., Dowling, B.A., Sargent, P. A., Sharpley, A. L. and Cowen, P. J. Melatonin phase advances circadian rhythm. Psychopharmacol., 1995, 121: 503-505.
3. Badia, P., Myers, B., Boecker, M. and Culpepper, J. Bright light effects on body temperature, alertness, EEG and behavior. Physiol. and Behav., 1991, 50: 583-588.
4. Boivin, D. B., Duffy, J. F., Kronauer, R. E. and Czeisler, C. A. Dose-response relationships for resetting of human circadian clock by light. Nature, 1996, 379: 540-542.
5. Bunnell, D. E., Scott, P. T., Nathan, H. P. and Berger, R. J. Effects of evening bright light exposure on melatonin, body temperature and sleep. J. Sleep Res., 1992, 1: 17-23.
6. Cajochen, C., Dijk, D. J. and Borbély, A. A. Dynamics of EEG slow-wave activity and core body temperature in human sleep after exposure to bright light. Sleep, 1992, 15: 337-343.
7. Cajochen, C., Kräuchi, K., Danilenko, K. V., Renz, C. and Wirz-Justice, A. Melatonin and bright light interactions on the waking EEG. Sleep Res., 1997a, 26: 70.
8. Cajochen, C., Kräuchi, K., Möri, D., Graw, P. and Wirz-Justice, A. Melatonin and S-20098 increase REM sleep and wake-up propensity without modifying NREM sleep homeostasis. Am. J. Physiol., 1997b, 272: R1189-R1196.
9. Cajochen, C., Kräuchi, K., von Arx, M. A., Möri, D., Graw, P. and Wirz-Justice, A. Daytime melatonin administration enhances sleepiness and theta/alpha activity in the waking EEG. Neurosci. Lett., 1996, 207: 209-213.
10. Campbell, S. S., Terman, M., Lewy, A. J., Dijk, D. J., Eastman, C. I. and Boulos, Z. Light treatment for sleep disorders; consensus report. Alerting and activating effects. J. Biol. Rhythms, 1995, 10: 151-154.
11. Carrier, J. and Dumont, M. Sleep propensity and sleep architecture after bright light exposure at three different times of day. J. Sleep Res., 1995, 4: 202-211.
12. Czeisler, C. A. The effect of light on the human circadian pacemaker. In: Circadian Clocks and Their Adjustment, edited by Waterhouse, J. M. Chichester (Ciba Found Symp 183): John Wiley and Sons, Inc. 1995, p. 254-302.
13. Czeisler, C. A., Zimmermann J. C., Ronda, J. M., Moore-Ede, M. C. and Weitzmann, E. D. Timing of REM sleep is coupled to the circadian rhythm of body temperature in man. Sleep, 1980, 2: 329-346.
14. Danilenko, K. V., Terman, M., Kräuchi, K., Cajochen, C., Weber, J. M. and Wirz-Justice, A. Dawn simulation phase advances human dim-light melatonin onset. Sleep Res., 1997 26: 708.
15. Deacon, S. and Arendt, J. Melatonin-induced temperature suppression and its acute phase-shifting effects correlate in a dose-dependent manner in humans. Brain Res., 1995 688: 77-85.
16. Deboer, T. and Tobler, A. Moderate body temperature changes and the sleep EEG power spectrum. Third annual meeting of the Swiss Society for Neuroscience and the Swiss Society for Biological Psychiatry, Lausanne, Switzerland, 1997, abstract 08 02.
17. Dijk, D. J., Beersma, D. G. M., Daan, S. and Lewy, A. J. Bright morning light advances the human circadian system without affecting NREM sleep homeostasis. Am. J. Physiol., 1989 256: R106-R111.
18. Dijk, D. J. and Cajochen, C. Melatonin and the circadian regulation of sleep initiation, consolidation, structure, and the sleep EEG. J. Biol. Rhythms, 1997 12: 627-635.
19. Dijk, D. J. and Czeisler, C. A. Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves and sleep spindle activity in humans. J. Neurosci., 1995a, 15: 3526-3538.
20. Dijk, D.J., Cajochen, C. and Borbély, A.A. Effect of a single 3-hour exposure to bright light on core body temperature and sleep in humans. Neurosci. Lett., 1991 121: 59-62.
21. Dijk, D.J., Roth, C., Landolt, H.P., Werth, E., Aeppli, M., Achermann, P. and Borbély, A.A. Melatonin effect on daytime sleep in men: suppression or EEG low frequency activity and enhancement of spindle frequency activity. Neurosci. Lett., 1995b, 201: 13-16.
22. Dollins, A.B., Zhdanova, I.V., Wurtman, R.J., Lynch, H.J. and Deng, M.H. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc. Natl. Acad. Sci., 1994, 91: 1824-1828.
23. Drennan, M., Kripke, D.F. and Gillin, J.C. Bright light can delay human temperature rhythm independent of sleep. Am. J. Physiol., 1989, 257: R136-R141.
24. Feinberg, I. and Floyd, T. C. Systematic trends across the night in human sleep cycles. Psychophysiology, 1979, 16: 283-291.
25. Gillberg, M., Kecklund, G. and Åkerstedt, T., Relations between performance and subjective ratings of sleepiness during a night awake. Sleep, 1994 17: 236-241.
26. Hughes, R.J. and Badia, P. Sleep-promoting and hypothermic effects of daytime melatonin administration in humans. Sleep, 1997, 20: 124-131.
27. Kräuchi, K., Cajochen, C., Danilenko, K.V. and Wirz Justice, A. The hypothermic effect of melatonin does not block the phase delay induced by bright light. Neurosci. Lett., 1997a, 232: 57-61.
28. Kräuchi, K., Cajochen, C., Möri, D., Graw, P. and Wirz Justice, A. Early evening melatonin and S 20098 advance circadian phase and nocturnal regulation of core body temperature. Am. J. Physiol., 1997b, 41: R1178-R1188.
29. Lewy, A.J. and Sack, R.L. Exogenous melatonin's phase shifting effects on the endogenous melatonin profile in sighted humans: a brief review and critique of the literature. J. Biol. Rhythms, 1997, 12: 588-594.
30. Lewy, A.J., Wehr, T.A., Goodwin, F.K., Newsome, D.A. and Markey, S.P. Light suppresses melatonin secretion in humans. Science, 1980, 210: 1267-1269.
31. McIntyre, I.M., Norman, T.R., Burrows, G.D. and Armstrong, S.M. Human melatonin suppression by light is intensity dependent. J. Pineal Res., 1989, 6: 149-156.
32. Minors, D. S., Waterhouse, J. M. and Wirz-Justice, A. A human phase-response curve to light. Neurosci. Lett., 1991, 133: 36-40.
33. Rechtschaffen, A. and Kales, A. A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. US dep. of Health, Education and Welfare, Public Health Service, Bethesda, Maryland, 1968.
34. Redman, J.R. Circadian entrainment and phase shifting in mammals with melatonin. J. Biol. Rhythms, 1997, 12: 581-587.
35. Reid, K., VandenHeuvel, C. and Dawson, D. Daytime melatonin administration: effects on core temperature and sleep onset latency. J. Sleep Res., 1996, 5: 150-154.
36. Sack, R. L., Blood, M. L., Ormerod, G. M., Rich, G. B. and Lewy, A. J. Oral melatonin reverses the alerting effects of nocturnal bright light exposure in humans. Sleep Res., 1992, 21: 49.
37. Sack, R. L., Lewy, A. J., Miller, L. S. and Singer, C. M. Effects of morning versus evening bright light exposure on REM latency. Biol. Psychiat., 1986, 21: 410-413.
38. Strassman, R. J., Quails, C. R., Lisansky, E. J. and Peake, G. T. Elevated rectal temperature produced by all-night bright light is reversed by melatonin infusion in men. J. Appl. Physiol., 1991, 71: 2178-2182.
39. Trachsel, L., Dijk, D.J., Brunner, D.P., Kiene, C. and Borbely, A.A. Effect of zopiclone and midazolam on sleep and EEG spectra in a phase-advanced sleep schedule. Neuropsychopharmacol., 1990, 3: 11-18.
40. Tzischinsky, O. and Lavie, P. Melatonin possesses time dependent hypnotic effects. Sleep, 1994, 17: 638-645.
41. Wehr, T. A brain-warming function of REM sleep. Neurosci. Biobehav. Rev., 1992, 16: 379-397.
42. Zhdanova, I. V. and Wurtman, R. J. Efficacy of melatonin as a sleep-promoting agent. J. Biol. Rhythms, 1997, 12: 644-650.
43. Zulley, J. Distribution of REM sleep in entrained 24 hour and free-running sleep-wake cycles. Sleep, 1980, 2: 377-389.