-
1
-
-
0027369366
-
Differential activation of cyclophosphamide and ifosfamide by cytochromes P-450 2B and 3A in human liver microsomes
-
CHANG, T. K. H., WEBER, G. F., CRESPI, C. L. and WAXMAN, D. J., 1993, Differential activation of cyclophosphamide and ifosfamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Research, 53, 5629-5637.
-
(1993)
Cancer Research
, vol.53
, pp. 5629-5637
-
-
Chang, T.K.H.1
Weber, G.F.2
Crespi, C.L.3
Waxman, D.J.4
-
2
-
-
0031024382
-
Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4-potential contribution to high first-pass metabolism
-
FITZSIMMONS, M. E. and COLLINS, J. M., 1997, Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4-potential contribution to high first-pass metabolism. Drug Metabolism and Disposition, 25, 256-266.
-
(1997)
Drug Metabolism and Disposition
, vol.25
, pp. 256-266
-
-
Fitzsimmons, M.E.1
Collins, J.M.2
-
3
-
-
0023035082
-
Dechloroethylation of ifosfamide and neurotoxicity
-
GOREN, M. P., WRIGHT, R. K.,PRATT, C. B. and PELL, P. E., 1986, Dechloroethylation of ifosfamide and neurotoxicity. Lancet, ii, 1219-1220.
-
(1986)
Lancet
, vol.2
, pp. 1219-1220
-
-
Goren, M.P.1
Wright, R.K.2
Pratt, C.B.3
Pell, P.E.4
-
4
-
-
0025057187
-
Metabolism of drugs and other xenobiotics in the gut lumen and wall
-
ILTT, K. F., TEE, L. B. G., REEVES, P. T. and MINCHIN, R. F., 1990, Metabolism of drugs and other xenobiotics in the gut lumen and wall. Pharmacology Therapeutics, 46, 67-93.
-
(1990)
Pharmacology Therapeutics
, vol.46
, pp. 67-93
-
-
Iltt, K.F.1
Tee, L.B.G.2
Reeves, P.T.3
Minchin, R.F.4
-
5
-
-
0028054999
-
Extrahepatic metabolism of drugs in humans
-
KRISHNA, D. R. and KLOTZ, U., 1994, Extrahepatic metabolism of drugs in humans. Clinical Pharmacokinetics, 26, 144-160.
-
(1994)
Clinical Pharmacokinetics
, vol.26
, pp. 144-160
-
-
Krishna, D.R.1
Klotz, U.2
-
6
-
-
0027437478
-
The analysis of ifosfamide and its metabolite
-
KAIJSER, G. P., KORST, A., BEIJNEN, J. H., BULT, A. and UNDERBERG, W. J. M., 1993, The analysis of ifosfamide and its metabolite. Anticancer Research, 13, 1311-1324.
-
(1993)
Anticancer Research
, vol.13
, pp. 1311-1324
-
-
Kaijser, G.P.1
Korst, A.2
Beijnen, J.H.3
Bult, A.4
Underberg, W.J.M.5
-
7
-
-
0026598851
-
Small intestinal cytochromes P450
-
KAMINSKY, L. and FASCO, M. J., 1992, Small intestinal cytochromes P450. Critical Review of Toxicology, 21, 407-422.
-
(1992)
Critical Review of Toxicology
, vol.21
, pp. 407-422
-
-
Kaminsky, L.1
Fasco, M.J.2
-
9
-
-
0026657789
-
Cytochrome P-450-mediated N-dechloroethylation of cyclophosphamide and ifosfamide in the rat
-
RUZICKA, J. A. and RUENITZ, P. C., 1992, Cytochrome P-450-mediated N-dechloroethylation of cyclophosphamide and ifosfamide in the rat. Drug Metabolism and Disposition, 20, 770-772.
-
(1992)
Drug Metabolism and Disposition
, vol.20
, pp. 770-772
-
-
Ruzicka, J.A.1
Ruenitz, P.C.2
-
10
-
-
0028183382
-
Ifosfamide clinical pharmacokinetics
-
WAGNER, T., 1994, Ifosfamide clinical pharmacokinetics. Clinical Pharmacokinetics, 26, 439-456.
-
(1994)
Clinical Pharmacokinetics
, vol.26
, pp. 439-456
-
-
Wagner, T.1
-
11
-
-
0028354930
-
Ifosfamide stereoselective dechloroethylation and neurotoxicity
-
WAINER, I. W., DUCHARME, J., GRANVIL, C. P., TRUDEAN, M. and LEYLAND-JONES, B., 1994, Ifosfamide stereoselective dechloroethylation and neurotoxicity. Lancet, 343, 982-983.
-
(1994)
Lancet
, vol.343
, pp. 982-983
-
-
Wainer, I.W.1
Ducharme, J.2
Granvil, C.P.3
Trudean, M.4
Leyland-Jones, B.5
-
12
-
-
0028178551
-
Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide
-
WALKER, D., FLINOIS, J. P., MONKMAN, S. C., BELOC, C., BODDY, A. V., CHOLERTON, S., DALY, A. K., LIND, M. J., PEARSON, A. D. J., BEAUNE, P. H. and IDLE, J. R., 1994, Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide. Biochemical Pharmacology, 47, 1157-1163.
-
(1994)
Biochemical Pharmacology
, vol.47
, pp. 1157-1163
-
-
Walker, D.1
Flinois, J.P.2
Monkman, S.C.3
Beloc, C.4
Boddy, A.V.5
Cholerton, S.6
Daly, A.K.7
Lind, M.J.8
Pearson, A.D.J.9
Beaune, P.H.10
Idle, J.R.11
-
13
-
-
0029012073
-
Identification of new metabolites of ifosfamide in rat urine using ion cluster technique
-
WANG, J. H. and CHAN, K. K., 1995a, Identification of new metabolites of ifosfamide in rat urine using ion cluster technique. Journal of Mass Spectrometry, 30, 675-683.
-
(1995)
Journal of Mass Spectrometry
, vol.30
, pp. 675-683
-
-
Wang, J.H.1
Chan, K.K.2
-
14
-
-
0029557939
-
Analysis of ifosfamide, 4-hydroxyifosfamide, N2-dechloroethylifosfamide, N3-dechloroethylifosfamide, and iphosphamide mustard in plasma by gas chromatography-mass spectrometry
-
WANG, J. H. and CHAN, K. K., 1995b, Analysis of ifosfamide, 4-hydroxyifosfamide, N2-dechloroethylifosfamide, N3-dechloroethylifosfamide, and iphosphamide mustard in plasma by gas chromatography-mass spectrometry. Journal of Chromatography, 674, 205-217.
-
(1995)
Journal of Chromatography
, vol.674
, pp. 205-217
-
-
Wang, J.H.1
Chan, K.K.2
-
15
-
-
0027174822
-
Activation of the anti-cancer drug ifosfamide by rat liver microsomal P450 enzymes
-
WEBER, G. F. and WAXMAN, D. J., 1993, Activation of the anti-cancer drug ifosfamide by rat liver microsomal P450 enzymes. Biochemical Pharmacology, 45, 1685-1694.
-
(1993)
Biochemical Pharmacology
, vol.45
, pp. 1685-1694
-
-
Weber, G.F.1
Waxman, D.J.2
-
16
-
-
0030476592
-
Role of cytochrome P450 in oxazaphosphorine metabolism, deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochrome P450
-
YU, L. and WAXMAN, D. J., 1996, Role of cytochrome P450 in oxazaphosphorine metabolism, deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochrome P450. Drug Metabolism and Disposition, 24, 1254-1262.
-
(1996)
Drug Metabolism and Disposition
, vol.24
, pp. 1254-1262
-
-
Yu, L.1
Waxman, D.J.2
-
17
-
-
9044236908
-
Characterization of rat small intestinal cytochrome P450 composition and inducibility
-
ZHANG, Q. Y., WIKOFF, J., DUNBAR, D. and KAMINSKY, L., 1996, Characterization of rat small intestinal cytochrome P450 composition and inducibility. Drug Metabolism and Disposition, 24, 322-328.
-
(1996)
Drug Metabolism and Disposition
, vol.24
, pp. 322-328
-
-
Zhang, Q.Y.1
Wikoff, J.2
Dunbar, D.3
Kaminsky, L.4
|