Synthesis of new bifunctional compounds which selectively alkylate guanines in DNA

Anti-Cancer Drug Design

Volumn 13, Issue 7, 1998, Pages 749-768

  Henderson, Nicola D ^a   Lacy, Stephen M ^a   O'Hare, C Caroline ^b   Hartley, John A ^b   McClean, Siobhan ^c   Wakelin, Laurence P G ^c,d   Kelland, Lloyd R ^e   Robins, David J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c St Luke's Inst for Cancer Research   (Ireland)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Alkylating agent; Bispiperidine; DNA cross linking; Sequence specificity

Indexed keywords

ALKYLATING AGENT; AZIRIDINE; CARBAMIC ACID DERIVATIVE; GUANINE; PIPERIDINE DERIVATIVE;

ARTICLE; CARCINOMA CELL; CELL STRAIN HT29; CELL STRAIN K 562; DNA ALKYLATION; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, ALKYLATING; BASE SEQUENCE; CROSS-LINKING REAGENTS; DNA; GUANINE; HT29 CELLS; HUMANS; MOLECULAR SEQUENCE DATA;

BRASSICACEAE;

EID: 0031686466     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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