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Volumn 24, Issue 4, 1998, Pages 309-320

Laboratory diagnosis of hereditary thrombophilia

Author keywords

Antithrombin; APC resistance; Protein C; Protein S; Thromboembolism; Thrombophilia; Thrombosis

Indexed keywords

ANTITHROMBIN; PROTEIN C; PROTEIN S; PROTHROMBIN;

EID: 0031684714     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-996019     Document Type: Review
Times cited : (36)

References (65)
  • 1
    • 0001316897 scopus 로고
    • Regulation of the hemostatic mechanism
    • G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. Philadelphia: Saunders
    • Rosenberg RD. Regulation of the hemostatic mechanism. In: G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. The Molecular Basis of Blood Diseases. Philadelphia: Saunders; 1987:534-574
    • (1987) The Molecular Basis of Blood Diseases , pp. 534-574
    • Rosenberg, R.D.1
  • 2
    • 0002437420 scopus 로고
    • Vitamin K-dependent proteins
    • G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. Philadelphia: Saunders
    • Stenflo J, Dahlbäck B. Vitamin K-dependent proteins. In: G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. The Molecular Basis of Blood Diseases. Philadelphia: Saunders; 1994:565-598
    • (1994) The Molecular Basis of Blood Diseases , pp. 565-598
    • Stenflo, J.1    Dahlbäck, B.2
  • 3
    • 0029664592 scopus 로고    scopus 로고
    • VIDAS D-Dimer: Fast quantitative ELISA for measuring D-Dimer in plasma
    • Pittet J-L, de Moerloose Ph, Reber G, et al. VIDAS D-Dimer: fast quantitative ELISA for measuring D-Dimer in plasma. Clin Chem 1996;42:410-415
    • (1996) Clin Chem , vol.42 , pp. 410-415
    • Pittet, J.-L.1    De Moerloose, Ph.2    Reber, G.3
  • 4
    • 0029086642 scopus 로고
    • Biochemical and molecular aspects of the coagulation cascade
    • Davie EW. Biochemical and molecular aspects of the coagulation cascade. Thromb Haemostas 1995;74:1-6
    • (1995) Thromb Haemostas , vol.74 , pp. 1-6
    • Davie, E.W.1
  • 5
    • 0030742896 scopus 로고    scopus 로고
    • Thrombin, thrombomodulin and TAFI in the molecular link between coagulation and fibrinolysis
    • Nesheim M, Wang W, Boffa M, Nagashima M, Morser J, Bajzar L. Thrombin, thrombomodulin and TAFI in the molecular link between coagulation and fibrinolysis. Thromb Haemostas 1997;78:386-391
    • (1997) Thromb Haemostas , vol.78 , pp. 386-391
    • Nesheim, M.1    Wang, W.2    Boffa, M.3    Nagashima, M.4    Morser, J.5    Bajzar, L.6
  • 6
    • 0029044322 scopus 로고    scopus 로고
    • Purification and characterization of TAFI, a thrombin activatable fibrinolysis inhibitor
    • Bajzar L, Manuel R, Nesheim M. Purification and characterization of TAFI, a thrombin activatable fibrinolysis inhibitor. J Biol Chem 1996;271:14477-14484
    • (1996) J Biol Chem , vol.271 , pp. 14477-14484
    • Bajzar, L.1    Manuel, R.2    Nesheim, M.3
  • 7
    • 0029895009 scopus 로고    scopus 로고
    • TAFI, or plasma procarboxypeptidase B, couples the coagulant and fibrinolytic cascades through the thrombin/thrombomodulin complex
    • Bajzar L, Morser J, Nesheim M. TAFI, or plasma procarboxypeptidase B, couples the coagulant and fibrinolytic cascades through the thrombin/thrombomodulin complex. J Biol Chem 1996;271:16603-16608
    • (1996) J Biol Chem , vol.271 , pp. 16603-16608
    • Bajzar, L.1    Morser, J.2    Nesheim, M.3
  • 8
    • 0001627642 scopus 로고
    • Inherited antithrombin deficiency causing thrombophilia
    • Egeberg O. Inherited antithrombin deficiency causing thrombophilia. Thromb Diath Haemorrh 1965;13:516-530
    • (1965) Thromb Diath Haemorrh , vol.13 , pp. 516-530
    • Egeberg, O.1
  • 11
    • 0021101168 scopus 로고
    • Congenital protein C deficiency and venous thromboembolism. A study of three Dutch families
    • Broekmans AW, Veltkamp JJ, Bertina RM. Congenital protein C deficiency and venous thromboembolism. A study of three Dutch families. N Engl J Med 1983;309:340-344
    • (1983) N Engl J Med , vol.309 , pp. 340-344
    • Broekmans, A.W.1    Veltkamp, J.J.2    Bertina, R.M.3
  • 12
    • 0021741550 scopus 로고
    • Familial protein S deficiency is associated with recurrent thrombosis
    • Comp PC, Nixon RR, Cooper MR, Esmon CT. Familial protein S deficiency is associated with recurrent thrombosis. J Clin Invest 1984;74:2082-2088
    • (1984) J Clin Invest , vol.74 , pp. 2082-2088
    • Comp, P.C.1    Nixon, R.R.2    Cooper, M.R.3    Esmon, C.T.4
  • 13
    • 0021873383 scopus 로고
    • Hereditary protein S deficiency and venous thromboembolism. A study in three Dutch families
    • Broekmans AW, Bertina RM, Reinalda Poot J. Hereditary protein S deficiency and venous thromboembolism. A study in three Dutch families. Thromb Haemostas 1985;53:273-277
    • (1985) Thromb Haemostas , vol.53 , pp. 273-277
    • Broekmans, A.W.1    Bertina, R.M.2    Reinalda Poot, J.3
  • 14
    • 0026695880 scopus 로고
    • Thromboembolic disease, critical evaluation of laboratory investigation
    • Malm J, Laurell M, Nilsson IM, Dahbäck B. Thromboembolic disease, critical evaluation of laboratory investigation. Thromb Haemostas 1992;68:7-13
    • (1992) Thromb Haemostas , vol.68 , pp. 7-13
    • Malm, J.1    Laurell, M.2    Nilsson, I.M.3    Dahbäck, B.4
  • 15
    • 0025241268 scopus 로고
    • Deficiencies of coagulation inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis
    • Heijboer H, Brandjes D, Büller HR, Sturk A, ten Cate JW. Deficiencies of coagulation inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis. N Engl J Med 1990; 323:1512-1516
    • (1990) N Engl J Med , vol.323 , pp. 1512-1516
    • Heijboer, H.1    Brandjes, D.2    Büller, H.R.3    Sturk, A.4    Ten Cate, J.W.5
  • 16
    • 0025855781 scopus 로고
    • Incidence and clinical characteristics of hereditary disorders associated with venous thrombosis
    • Taberno MD, Tomas JF, Alberca I, Orfao I, Borrasca AL, Vicente V. Incidence and clinical characteristics of hereditary disorders associated with venous thrombosis. Am J Hematol 1991;36: 249-254
    • (1991) Am J Hematol , vol.36 , pp. 249-254
    • Taberno, M.D.1    Tomas, J.F.2    Alberca, I.3    Orfao, I.4    Borrasca, A.L.5    Vicente, V.6
  • 17
    • 0023233223 scopus 로고
    • Absence of thrombosis in subjects with heterozygous protein C deficiency
    • Miletich J, Sherman I, Broze G. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 1987;317:991-996
    • (1987) N Engl J Med , vol.317 , pp. 991-996
    • Miletich, J.1    Sherman, I.2    Broze, G.3
  • 18
    • 0027446268 scopus 로고
    • Familial thrombophilia due to previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
    • Dahbäck B, Carlsson M, Svensson PJ. Familial thrombophilia due to previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 1993;90:1004-1008
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1004-1008
    • Dahbäck, B.1    Carlsson, M.2    Svensson, P.J.3
  • 19
    • 0028314865 scopus 로고
    • Mutation in blood coagulation factor V associated with resistance to activated protein C
    • Bertina RM, Koeleman PC, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994;369:64-67
    • (1994) Nature , vol.369 , pp. 64-67
    • Bertina, R.M.1    Koeleman, P.C.2    Koster, T.3
  • 21
    • 0028098210 scopus 로고
    • Resistance to activated protein C as basis for venous thrombosis
    • Svensson PJ, Dahlbäck B. Resistance to activated protein C as basis for venous thrombosis. N Engl J Med 1994;330:517-522
    • (1994) N Engl J Med , vol.330 , pp. 517-522
    • Svensson, P.J.1    Dahlbäck, B.2
  • 22
    • 0029850530 scopus 로고    scopus 로고
    • A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
    • Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3698-2703
    • (1996) Blood , vol.88 , pp. 3698-12703
    • Poort, S.R.1    Rosendaal, F.R.2    Reitsma, P.H.3    Bertina, R.M.4
  • 23
    • 0030792668 scopus 로고    scopus 로고
    • The prothrombin gene G20210a variant: Prevalence in a U.K. anticoagulant clinic population
    • Cumming AM, Keeney S, Salden A, Bhavnani M, Shwe KH, Hay CRM. The prothrombin gene G20210A variant: prevalence in a U.K. anticoagulant clinic population. Br J Haematol 1997; 98:353-355
    • (1997) Br J Haematol , vol.98 , pp. 353-355
    • Cumming, A.M.1    Keeney, S.2    Salden, A.3    Bhavnani, M.4    Shwe, K.H.5    Hay, C.R.M.6
  • 24
    • 0030810628 scopus 로고    scopus 로고
    • Risk of venous thromboembolism associated with a G to a transition at position 20210 in the 3′untranslated region of the prothrombin gene
    • Brown K, Luddington R, Williamson D, Baker P, Baglin T. Risk of venous thromboembolism associated with a G to A transition at position 20210 in the 3′untranslated region of the prothrombin gene. Br J Haematol 1997;98:907-909
    • (1997) Br J Haematol , vol.98 , pp. 907-909
    • Brown, K.1    Luddington, R.2    Williamson, D.3    Baker, P.4    Baglin, T.5
  • 25
    • 0028954459 scopus 로고
    • The first mutation identified in the thrombomodulin gene in a 45-year old male presenting with thromboembolic disease
    • Öhlin A-K, Marlar RA. The first mutation identified in the thrombomodulin gene in a 45-year old male presenting with thromboembolic disease. Blood 1995;85:330-336
    • (1995) Blood , vol.85 , pp. 330-336
    • Öhlin, A.-K.1    Marlar, R.A.2
  • 26
    • 0030746620 scopus 로고    scopus 로고
    • Thrombomodulin gene variations and thromboembolic disease
    • Öhlin A-K, Norlund L, Marlar RA. Thrombomodulin gene variations and thromboembolic disease. Thromb Haemostas 1997; 78:396-400
    • (1997) Thromb Haemostas , vol.78 , pp. 396-400
    • Öhlin, A.-K.1    Norlund, L.2    Marlar, R.A.3
  • 27
    • 0030877119 scopus 로고    scopus 로고
    • Activated protein C resistance, a major risk factor for thrombosis
    • Rosén SB, Sturk A. Activated protein C resistance, a major risk factor for thrombosis. Eur J Chem Clin Biochem 1997;35: 501-516
    • (1997) Eur J Chem Clin Biochem , vol.35 , pp. 501-516
    • Rosén, S.B.1    Sturk, A.2
  • 28
    • 0027291270 scopus 로고    scopus 로고
    • Antithrombin III mutation database: First update
    • 199
    • Lane DA, Olds RJ, Boisclair M, et al. Antithrombin III mutation database: First update. Thromb Haemostas 199;70:361-369
    • Thromb Haemostas , vol.70 , pp. 361-369
    • Lane, D.A.1    Olds, R.J.2    Boisclair, M.3
  • 29
    • 0028300171 scopus 로고
    • Antithrombin and its inherited deficiencies
    • Perry D. Antithrombin and its inherited deficiencies. Blood Rev 1994;8:37-55
    • (1994) Blood Rev , vol.8 , pp. 37-55
    • Perry, D.1
  • 30
    • 0031042986 scopus 로고    scopus 로고
    • Antithrombin mutation database: 2nd (1997) update
    • Lane DA, Bayston T, Lods RJ, et al. Antithrombin mutation database: 2nd (1997) update. Thromb Haemostas 1997;77:197-211
    • (1997) Thromb Haemostas , vol.77 , pp. 197-211
    • Lane, D.A.1    Bayston, T.2    Lods, R.J.3
  • 31
    • 0002425830 scopus 로고
    • Regulation of blood coagulation by protease inhibitors
    • G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. Philadelphia: Saunders
    • Broze GJ, Tolefsen DM. Regulation of blood coagulation by protease inhibitors. In: G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. The Molecular Basis of Blood Diseases. Philadelphia: Saunders; 1994:629-656
    • (1994) The Molecular Basis of Blood Diseases , pp. 629-656
    • Broze, G.J.1    Tolefsen, D.M.2
  • 32
    • 0026434005 scopus 로고
    • Heparin
    • Hirsh J, Heparin. N Engl J Med 1991;324:1565-1574
    • (1991) N Engl J Med , vol.324 , pp. 1565-1574
    • Hirsh, J.1
  • 33
    • 0026593425 scopus 로고
    • Low molecular weight heparin
    • Hirsh J, Levin MN. Low molecular weight heparin. Blood 1992; 79:1-17
    • (1992) Blood , vol.79 , pp. 1-17
    • Hirsh, J.1    Levin, M.N.2
  • 34
    • 0027259395 scopus 로고
    • Low molecular weight heparin
    • Hirsh J. Low molecular weight heparin. Thromb Haemostas 1993;70:204-207
    • (1993) Thromb Haemostas , vol.70 , pp. 204-207
    • Hirsh, J.1
  • 35
    • 0001976355 scopus 로고
    • The protein C anticoagulant system
    • G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. Philadelphia: Saunders
    • Dahlbäck B, Stenflo J. The protein C anticoagulant system. In: G Stamatoyannapoulos, AW Nienhuis, PW Majerus, H Varmus, eds. The Molecular Basis of Blood Diseases. Philadelphia: Saunders: 1994:599-628
    • (1994) The Molecular Basis of Blood Diseases , pp. 599-628
    • Dahlbäck, B.1    Stenflo, J.2
  • 36
    • 0028832910 scopus 로고
    • The protein C anticoagulant system: Inherited defects as basis for venous thrombosis
    • Dahbäck B. The protein C anticoagulant system: Inherited defects as basis for venous thrombosis. Thromb Res 1995;77: 1-43
    • (1995) Thromb Res , vol.77 , pp. 1-43
    • Dahbäck, B.1
  • 39
    • 0023626864 scopus 로고
    • An International collaborative study on the performance of protein C antigen assays
    • Bertina. An International collaborative study on the performance of protein C antigen assays. Thromb Haemostas 1987;57:112-117
    • (1987) Thromb Haemostas , vol.57 , pp. 112-117
    • Bertina1
  • 40
    • 0023615863 scopus 로고
    • Multicenter comparison of five functional and two immunological assays for protein C
    • Mannucci PM, Boyer C, Tripodi A, et al. Multicenter comparison of five functional and two immunological assays for protein C. Thromb Haemostas 1987;57:44-48
    • (1987) Thromb Haemostas , vol.57 , pp. 44-48
    • Mannucci, P.M.1    Boyer, C.2    Tripodi, A.3
  • 41
    • 0023701635 scopus 로고
    • Functional assays of protein C: Comparison of two snake-venom assays with two thrombin assays
    • Franchi F, Tripodi A, Valsecchi C, Mannucci PM. Functional assays of protein C: Comparison of two snake-venom assays with two thrombin assays. Thromb Haemostas 1988;60:145-147
    • (1988) Thromb Haemostas , vol.60 , pp. 145-147
    • Franchi, F.1    Tripodi, A.2    Valsecchi, C.3    Mannucci, P.M.4
  • 42
    • 0027230858 scopus 로고
    • A sensitive and facile assay for the measurement of activated protein C activity levels in vivo
    • Orthner CL, Kolen B, Drohan WN. A sensitive and facile assay for the measurement of activated protein C activity levels in vivo. Thromb Haemostas 1993;69:441-447
    • (1993) Thromb Haemostas , vol.69 , pp. 441-447
    • Orthner, C.L.1    Kolen, B.2    Drohan, W.N.3
  • 43
    • 0026739904 scopus 로고
    • Hereditary protein C deficiency: Laboratory values in transmitters and guidelines for the diagnostic procedure
    • Pabinger I, Allart CF, Hermans J, Briët E, Bertina RM. Hereditary protein C deficiency: Laboratory values in transmitters and guidelines for the diagnostic procedure. Thromb Haemostas 1992;68:470-474
    • (1992) Thromb Haemostas , vol.68 , pp. 470-474
    • Pabinger, I.1    Allart, C.F.2    Hermans, J.3    Briët, E.4    Bertina, R.M.5
  • 44
    • 0027465837 scopus 로고
    • Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect
    • Allaart CF, Poort SR, Rosendaal FR, Reitsma PH, Bertina RM, Briet E. Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect. Lancet 1993;341:134-138
    • (1993) Lancet , vol.341 , pp. 134-138
    • Allaart, C.F.1    Poort, S.R.2    Rosendaal, F.R.3    Reitsma, P.H.4    Bertina, R.M.5    Briet, E.6
  • 45
    • 0023228592 scopus 로고
    • Rapid amidolytic assay of protein C in whole plasma using an activator from the venom of Agk-istrodon Contotrix
    • Francis RB, Seyfert U. Rapid amidolytic assay of protein C in whole plasma using an activator from the venom of Agk-istrodon Contotrix. Am J Clin Pathol 1987;87:619-625
    • (1987) Am J Clin Pathol , vol.87 , pp. 619-625
    • Francis, R.B.1    Seyfert, U.2
  • 46
    • 0029902451 scopus 로고    scopus 로고
    • Molecular basis for protein C hereditary deficiency
    • Aiach M, Gandrille S. Molecular basis for protein C hereditary deficiency. Haemostasis 1996;26 (Suppl 4):9-19
    • (1996) Haemostasis , vol.26 , Issue.4 SUPPL. , pp. 9-19
    • Aiach, M.1    Gandrille, S.2
  • 47
    • 0029876985 scopus 로고    scopus 로고
    • Inherited thrombophilia: Pathogenesis, clinical syndromes and management
    • De Stefano V, Finazzi G, Manucci PM. Inherited thrombophilia: Pathogenesis, clinical syndromes and management. Blood 1996;87:3531-3544
    • (1996) Blood , vol.87 , pp. 3531-3544
    • De Stefano, V.1    Finazzi, G.2    Manucci, P.M.3
  • 48
    • 0029017118 scopus 로고
    • Evaluation of the relationship between protein S and C4b-binding protein isoforms in hereditary protein S deficiency demonstrating type I and type III deficiencies to be phenotypic variants of the same genetic disease
    • Zoller B, Garcia de Frutos P, Dahlbäck B. Evaluation of the relationship between protein S and C4b-binding protein isoforms in hereditary protein S deficiency demonstrating type I and type III deficiencies to be phenotypic variants of the same genetic disease. Blood 1995;85:3542-3531
    • (1995) Blood , vol.85 , pp. 3542-13531
    • Zoller, B.1    Garcia De Frutos, P.2    Dahlbäck, B.3
  • 49
    • 0027742936 scopus 로고
    • Resistance to activated protein C in nine thrombophilic families: Interference in a protein S functional assay
    • Faioni EM, Franchi F, Asti D, Sacchi E, Bernardi F, Mannucci PM. Resistance to activated protein C in nine thrombophilic families: Interference in a protein S functional assay. Thromb Haemostas 1993;70:683-690
    • (1993) Thromb Haemostas , vol.70 , pp. 683-690
    • Faioni, E.M.1    Franchi, F.2    Asti, D.3    Sacchi, E.4    Bernardi, F.5    Mannucci, P.M.6
  • 51
    • 0024003059 scopus 로고
    • Acquired deficiency of protein S, protein S activity during oral anticoagulation, in liver disease, and in disseminated intravascular coagulation
    • D'Angelo A, Vigano-D'Angelo S, Esmon CT, Comp PC. Acquired deficiency of protein S, protein S activity during oral anticoagulation, in liver disease, and in disseminated intravascular coagulation. J Clin Invest 1988;81:1445-1454
    • (1988) J Clin Invest , vol.81 , pp. 1445-1454
    • D'Angelo, A.1    Vigano-D'Angelo, S.2    Esmon, C.T.3    Comp, P.C.4
  • 52
    • 0023038667 scopus 로고
    • Functional and immunological protein S levels are decreased during pregnancy
    • Comp PC, Thurnau GR, Welsh J, Esmon CT. Functional and immunological protein S levels are decreased during pregnancy. Blood 1986;68:881-885
    • (1986) Blood , vol.68 , pp. 881-885
    • Comp, P.C.1    Thurnau, G.R.2    Welsh, J.3    Esmon, C.T.4
  • 53
    • 0023922249 scopus 로고
    • Changes in the plasma levels of vitamin K-dependent proteins C and S and of C4b-binding protein during pregnancy and oral contraception
    • Malm J, Laurell M, Dahlbäck B. Changes in the plasma levels of vitamin K-dependent proteins C and S and of C4b-binding protein during pregnancy and oral contraception. Br J Haematol 1988;68:437-443
    • (1988) Br J Haematol , vol.68 , pp. 437-443
    • Malm, J.1    Laurell, M.2    Dahlbäck, B.3
  • 54
    • 0027428481 scopus 로고
    • Anticoagulant protein C pathway defective in majority of thrombophilic patients
    • Griffin JH, Evatt B, Wideman C, Fernandez JA. Anticoagulant protein C pathway defective in majority of thrombophilic patients. Blood 1993;82:1989-1993
    • (1993) Blood , vol.82 , pp. 1989-1993
    • Griffin, J.H.1    Evatt, B.2    Wideman, C.3    Fernandez, J.A.4
  • 55
    • 0028098218 scopus 로고
    • Inherited resistance to activated protein C is corrected by anticoagulant cofactor found to be a property of factor V
    • Dahbäck B, Hildebrand B. Inherited resistance to activated protein C is corrected by anticoagulant cofactor found to be a property of factor V. Proc Natl Acad Sci USA 1994;91:1396-1400
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1396-1400
    • Dahbäck, B.1    Hildebrand, B.2
  • 57
    • 0028291210 scopus 로고
    • Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis
    • Zöller B, Dahlbäck B. Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis. Lancet 1994;343:1536-1538
    • (1994) Lancet , vol.343 , pp. 1536-1538
    • Zöller, B.1    Dahlbäck, B.2
  • 60
    • 0030615077 scopus 로고    scopus 로고
    • 506 mutation. Evaluation of thirteen plasma-based methods for their diagnostic efficacy in comparison with DNA analysis
    • 506 mutation. Evaluation of thirteen plasma-based methods for their diagnostic efficacy in comparison with DNA analysis. Thromb Haemostas 1997;77:436-439
    • (1997) Thromb Haemostas , vol.77 , pp. 436-439
    • Tripodi, A.1    Negri, B.2    Bertina, R.M.3    Mannucci, P.M.4
  • 61
    • 0002837586 scopus 로고
    • Improved APC-resistance method based on a Russell's Viper Venom clotting test
    • Abst
    • Exner T, Murray B, Chong BH, Chesterman CN. Improved APC-resistance method based on a Russell's Viper Venom clotting test. Thromb Haemostas 1995;73:1119 (Abst)
    • (1995) Thromb Haemostas , vol.73 , pp. 1119
    • Exner, T.1    Murray, B.2    Chong, B.H.3    Chesterman, C.N.4
  • 63
    • 0030858704 scopus 로고    scopus 로고
    • A comparison between two activated protein C resistance methods as routine diagnostic tests for factor V Leiden mutation
    • Aboud MR, Ma DDF. A comparison between two activated protein C resistance methods as routine diagnostic tests for factor V Leiden mutation. Br J Haematol 1997;97:798-803
    • (1997) Br J Haematol , vol.97 , pp. 798-803
    • Aboud, M.R.1    Ma, D.D.F.2
  • 64
    • 0029845098 scopus 로고    scopus 로고
    • A prothrombinase based assay for the detection of resistance to activated protein C
    • Nicolaes GAF, Christella M Thomassan GD, et al. A prothrombinase based assay for the detection of resistance to activated protein C. Thromb Haemostas 1996;76:404-410
    • (1996) Thromb Haemostas , vol.76 , pp. 404-410
    • Nicolaes, G.A.F.1    Christella, M.2    Thomassan, G.D.3
  • 65
    • 0030895572 scopus 로고    scopus 로고
    • The clinical application of a new specific functional assay to detect the factor V Leiden mutation associated with activated protein C resistance
    • Van Oerle R, van Pampus L, Tans G, Rosing J, Hamulyák K. The clinical application of a new specific functional assay to detect the factor V Leiden mutation associated with activated protein C resistance. Am J Clin Pathol 1997;107:521-526
    • (1997) Am J Clin Pathol , vol.107 , pp. 521-526
    • Van Oerle, R.1    Van Pampus, L.2    Tans, G.3    Rosing, J.4    Hamulyák, K.5


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