A comparison between two activated protein C resistance methods as routine diagnostic tests for factor V Leiden mutation

British Journal of Haematology

Volumn 97, Issue 4, 1997, Pages 798-803

  Aboud, M R ^a   Ma, D D F ^a  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

APC resistance; Lupus anticoagulant; Thrombophilia; Warfarin therapy

Indexed keywords

ACTIVATED PROTEIN C; WARFARIN;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; HUMAN; MALE; NORMAL HUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; RELIABILITY; SCREENING TEST; THROMBOPHILIA;

EID: 0030858704     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.1432958.x     Document Type: Article

References (26)

1. Ausseil, F., Alhene Gelas, M., Pittet, J.L., Dupuy, G. & Aiach, M. (1995) A new chronometric assay for the research of factor V Leiden evaluated using venous thrombotic patients, patients under AVK treatment and normal controls. Thrombosis and Haemostasis, 73, 1362 (abstract 1770).
2. Beauchamp, N.J., Daly, M.E., Hampton, K.K., Cooper, P.C., Preston, E. & Peake, I.R. (1994) High prevalence of a mutation in the factor V gene within the UK population: relationship to activated protein C resistance and familial thrombosis. British Journal of Haematology, 88, 219-222.
3. Bertina, R.M., Koeleman, B.P.C., Koster, T., Rosendaal, F.R., Dirven, R.J., deRonde, H., van der Velden, P.A. & Reitsma, P.H. (1994) Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature, 369, 64-67.
4. Bertina, R.M., Reitsma, P., Rosendaal, F. & Vandenbroucke, J. (1995) Resistance to activated protein C and factor V Leiden as risk factors for venous thrombosis. Thrombosis and Haemostasis, 74, 449-453.
5. Bokarewa, M.I., Blomback, M., Egberg, N. & Rosen, S. (1994) A new varient of interaction between phospholipid antibodies and the protein C system. Blood Coagulation and Fibrinolysis, 5, 37-41.
6. Brandt, J.T., Barna, L.K. & Triplett, D.A. (1995) Laboratory identification of lupus anticoagulants: results of the second international workshop for identification of lupus anticoagulants. Thrombosis and Haemostasis, 74, 1597-1603.
7. Dahlback, B. (1995) Modified APC-resistance test offers increased sensitivity and specificity for the FV:Q506 allele. (Letter). Thrombosis and Haemostasis, 74, 1380-1381.
8. Dahlback, B., Carlsson, M. & Svensson, P.J. (1993) Familial thrombophilia due to a previous unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proceedings of the National Academy of Sciences of the United States of America, 90, 1004-1008.
9. de Ronde, H. & Bertina, R. (1994) Laboratory diagnosis of APC-resistance: a critical evaluation of the test and the development of diagnostic criteria. Thrombosis and Haemostasis, 72, 880-886.
10. Engel, H., Zwang, L., van Vilet, H.H.D.M., Michiels, J.J., Stibbe, J. & Lindemans, J. (1996) Phenotyping and genotyping of coagulation factor V Leiden. Thrombosis and Haemostasis, 75, 267-269.
11. Exner, T. (1995) Diagnostic methodologies for circulating anticoagulants. Thrombosis and Haemostasis, 74, 338-344.
12. Exner, T., Murray, B., Chong, B.H. & Chesterman, C.N. (1995) Improved APC-resistance method based on a Russell viper venom clotting test. Thrombosis and Haemostasis, 73, 1119 (abstract 839).
13. Gibson, J., Starling, E., Date, L., Rickard, K.A. & Kronenberg, H. (1988) Simplified screening procedure for detecting lupus inhibitor. Journal of Clinical Pathalogy, 41, 226-231.
14. Greengard, J.S., Sun, X., Xu, X., Fernandez, J.A., Griffin, J.H. & Evatt, B. (1994) Activated protein C resistance caused by Arg 506 Gln mutation in factor Va. Lancet, 343, 1361-1362.
15. Griffin, J., Heeb, M., Kojima, Y., Fernandez, J., Kojima, K., Hackeng, T. & Greengard, J. (1995) Activated protein C resistance: molecular mechanisms. Thrombosis and Haemostasis, 74, 444-448.
16. Halbmayer, W.M., Haushofer, A., Schon, R. & Fischer, M. (1994) Influence of lupus anticoagulant on a commercially available kit for APC resistance. Thrombosis and Haemostasis, 72, 645-6.
17. Jorquera, J.I., Montoro, J.M., Fernandez, M.A., Aznar, J.A. & Aznar, J. (1994) Modified test for activated protein C resistance. Lancet, 344, 1162-1163.
18. Le, D.T., Griffin, J.H., Greengard, J.S., Mujumdar, V. & Rapaport, I. (1995) Use of a generally applicable tissue factor-dependent factor V assay to detect activated portein C-resistant factor Va in patients receiving warfarin and patients with lupus anticoagulant. Blood, 85, 1704-1711.
19. Legani, C., Palareti, G., Biagi, R., Cocchei, S., Bernardi, F., Rosendaal, F.R., Reitsma, P.H., de Ronde, H. & Bertina, R.M. (1996) Activated protein C resistance: a comparison between two clotting assays and their relationship to the presence of the factor V Leiden mutation. British Journal of Haematology, 93, 694-699.
20. Ma, D.U.F., Aboud, M.R., Williams, B.G. & Isbister, J.P. (1995) Activated protein C resistance (APC) and inherited factor V (FV) mis-sense mutation in patients with venous and arterial thrombosis in a haematology clinic. Australia and New Zealand Journal of Medicine, 25, 151-154.
21. Roelse, J.C., Koopman, M.M.W., Buller, H.R., Ten Cate, J.W., Montaruli, B., van Mourik, J.A. & Voorberg, J. (1996) Absence of mutations at the activated protein C cleavage site of factor VIII in 125 patients with venous thrombosis. British Journal of Haematology, 92, 740-743.
22. Rosen, S., Lindberg, K. & Andersson, N-E. (1995) A new chromogenic APC resistance assay with high discrimination between absence and presence of the factor V mutation G1691 → A. Thrombosis and Haemostasis, 73, 1364 (abstract 1778).
23. Trossaert, M., Conard, J., Horellou, M.H. & Samama, M.M. (1995) Influence of storage conditions on activated protein C resistance assay. (Letter). Thrombosis and Haemostasis, 73, 163.
24. Trossaert, M., Conard, J., Horellou, M.H., Samama, M.M., Ireland, H., Bayston, T.A. & Lane, D.A. (1994) Modified APC resistance assay for patients on oral anticoagulants. Lancet, 344, 1709.
25. Voorberg, J., Roelse, J., Koopman, R., Buffer, H., Berends, F., Ten Cate, J.W., Mertens, K. & van Mourik, J.A. (1994) Association of idiopathic venous thromboembolism with single point mutation at Arg 506 of factor V. Lancet, 343, 1535-1536.
26. Zoller, B., Svensson, P.J., He, X. & Dahlback, B. (1994) Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C. Journal of Clinical Investigation, 94, 2521-2524.