A conservative amino acid mutation in the chromosome-encoded dihydrofolate reductase confers trimethoprim resistance in Streptococcus pneumoniae

Journal of Infectious Diseases

Volumn 178, Issue 3, 1998, Pages 700-706

  Pikis, Andreas ^a   Donkersloot, Jacob A ^b   Rodriguez, William J ^b   Keith, Jerry M ^b  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; TRIMETHOPRIM;

AMINO ACID SEQUENCE; ARTICLE; BACTERICIDAL ACTIVITY; DRUG DESIGN; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE;

EID: 0031684375     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515371     Document Type: Article

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