Microalbuminuria predicts cardiovascular events and renal insufficiency in patients with essential hypertension

Journal of Hypertension

Volumn 16, Issue 9, 1998, Pages 1325-1333

  Bigazzi, Roberto ^a   Bianchi, Stefano ^a   Baldari, Duccio ^a   Campese, Vito M ^b,c  

^a Asl 6 Livorno   (Italy)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c LAC USC MEDICAL CENTER   (United States)

Author keywords

Cardiovascular events; Cholesterol; Essential hypertension; Microalbuminuria; Renal function; Uric acid

Indexed keywords

ALBUMIN; CHOLESTEROL; CREATININE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; URIC ACID;

ADULT; AGE; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE CLEARANCE; DIASTOLIC BLOOD PRESSURE; ESSENTIAL HYPERTENSION; FEMALE; FOLLOW UP; HUMAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; PREDICTION; PRIORITY JOURNAL; REGRESSION ANALYSIS; RETROSPECTIVE STUDY; TRIACYLGLYCEROL BLOOD LEVEL; URIC ACID BLOOD LEVEL; URINARY EXCRETION;

EID: 0031681312     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199816090-00014     Document Type: Article

References (70)

1. Parving HH, Jensen HAE, Mogensen CE, Evrin PE. Increased urinary albumin excretion in benign essential hypertension. Lancet 1974; i:1190-1192.
2. Losito A, Fortunati F, Zampi I, Del Favero A. Impaired renal functional reserve and albuminuria in essential hypertension. BMJ 1988: 296:1562-1564.
3. Giaconi S, Levanti C, Fommei E, Innocenti F, Seghieri G, Palla L, et al. Microalbuminuria and casual and ambulatory blood pressure monitoring in normotensives and in patients with borderline and mild essential hypertension. Am J Hypertens 1989; 2:259-261
4. Pedersen EB, Mogensen CE. Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate, and renal plasma flow in patients with essential hypertension. Scand J Clin Lab Invest 1976; 36:231-237,
5. Bigazzi R, Bianchi S, Campese VM, Baldari G. Prevalence of microalbuminuria in a large population of patients with mild to moderate essential hypertension. Nephron 1992; 61:94-97.
6. Kannel WB. Hypertension and the risk of cardiovascular disease. In: Laragh JH, Brenner BM (editors): Hypertension: pathophysiology, diagnosis and management. New York: Raven Press; 1990. pp. 101-117.
7. Lewin A, Blaufox D, Castle H, Entwisle G, Langford H. Apparent prevalence of curable hypertension in the Hypertension Detection and Follow-up Program. Arch Intern Med 1985; 145:424-427.
8. Samuelsson O, Wilhelmsen L, Elmfeldt D, Pennert K, Wedel H, Wikstrand J, et al. Predictors of cardiovascular morbidity in treated hypertension: results from the primary preventive trial in Göteborg, Sweden. J Hypertens 1985; 3:167-176.
9. Yudkin JS, Forrest RD, Jackson CA. Microalbuminuria as predictor of vascular disease in non-diabetic subjects. Lancet 1988; ii:530-533.
10. Haffner SM, Stern MP, Gruber MKK, Hazuda HP, Mitchell BD, Patterson JK. Microalbuminuria. Potential marker for increased cardiovascular risk factor in nondiabetic subjects? Arteriosclerosis 1990; 10:727-731.
11. Bianchi S, Bigazzi R, Valtriani C, Chiapponi I, Sgherri G, Baldari G, et al. Elevated serum insulin levels in patients with essential hypertension and microalbuminuria. Hypertension 1994; 23:681-687.
12. Bianchi S, Bigazzi R, Quinones A, Muscelli E, Baldari G, Pecori N, et al. Insulin resistance in microalbuminuric hypertension: sites and mechanisms. Hypertension 1995; 26:789-795.
13. Bigazzi R, Bianchi S, Baldari G, Sgherri G, Campese VM. Diurnal variations of blood pressure and microalbuminuria in essential hypertension. Am J Hypertens 1994; 7:23-29.
14. Bigazzi R, Bianchi S, Nenci R, Baldari D, Baldari G, Campese VM. Increased thickness of the carotid artery in patients with essential hypertension and microalbuminuria. J Hum Hypertens 1995; 9:827-833.
15. Parving HH, Oxenboll B, Svendsen PA, Christiansen JS, Anderson AR. Early detection of patients at risk of developing diabetic nephropathy: a longitudinal study of urinary albumin excretion. Acta Endocrinol 1982; 100:550-555,
16. Viberti GC, Hill RD, Jarret RD, Argyropoulos A, Hammud U, Keen I. Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet 1982; i:1430-1432.
17. Mogensen CE. Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N Engl J Med 1986; 310:356-360.
18. The sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNCVIV). Arch Int Med 1997; 157:2413-2446.
19. Watts GF, Bennett JE, Rowe DJ, Morris RW, Gatling W, Shaw KM, et al. Assessment of immunochemical methods for determining low concentrations of albumin in urine. Clin Chem 1986; 32:1544-1548.
20. Silver A, Dawnay A, Landon J, Catteli WR. Immonoassays for low concentrations of albumin in urine. Clin Chem 1986; 32:1303-1306.
21. Opsahl JA, Abraham PA, Halstenson CE, Keane WF. Correlation of office and ambulatory blood pressure measurements with urinary albumin and N-acetyl-beta-D-glucosaminidase excretions in essential hypertension. Am J Hypertens 1988; 1:1175-1205.
22. Giaconi S, Levanti C, Fommei E, Innocenti F, Seghieri G, Palla L, et al. Microalbuminuria and casual and ambulatory blood pressure monitoring in normotensives and in patients with borderline and mild essential hypertension. Am J Hypertens 1989; 2:259-226.
23. Valvo E, Casagrande P, Bedogna V, Dal Santo F, Alberti D, Fontanarosa C, et al. Renal functional reserve in patients with essential hypertension: effect of inhibition of the renin-angiotensin system. Clin Sci 1990; 78:585-590.
24. Laville M, Doche C, Fauvel JP, Pozet N, Hadj-Aissa A, Zech P. Effect of beta-blockade on albumin excretion rate in essential hypertension. Nephron 1990; 54:183-184.
25. Pedersen EB, Mogensen CE. Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate and renal plasma flow in patients with essential hypertension. Scand J Clin Lab Invest 1976; 36:231-237.
26. Parving HH, Jensen HE, Mogensen CE, Evrin PE. Increased urinary albumin excretion in benign essential hypertension. Lancet 1974; i:231-237.
27. Gerber LM, Shmukler C, Alderman MH. Differences in urinary albumin excretion rate between normotensive and hypertensive white and non white subjects. Arch Intern Med 1992; 152:373-377.
28. James A, Fotherby MB, Potter JF. Screening tests for microalbuminuria in non diabetic elderly subjects and their relation to blood pressure. Clin Sci 1995; 88:185-190.
29. Losito A, Fortunati F, Zampi I, Del Favero A. Impaired renal functional reserve and albuminuria in essential hypertension. BMJ 1988; 296:1562-1564.
30. Yudkin JS, Forrest RD, Jackson CA. Microalbuminuria as predictor of vascular disease in non-diabetic subjects. Lancet 1988; ii:530-533.
31. Winocour PH, Harland J, Millar JP, Laker MF, Alberti KGMM. Microalbuminuria and associated risk factors in the community. Atherosclerosis 1992; 93:71-81.
32. West JNW, Gosling P, Dimmitt SB, Littler WA. Non-diabetic microalbuminuria in clinical practice and its relationship to posture, exercise and blood pressure. Clin Sci 1991; 81:373-377.
33. Mimram A. Microalbuminuria in essential hypertension. Clin Exper Hypertens 1993; 15:1061-1067.
34. Mimran A, Ribstein J, DuCailar G. Is microalbuminuria a marker of early intrarenal vascular dysfunction in essential hypertension? Hypertension 1994; 23:1018-1021.
35. Bianchi S, Bigazzi R, Baldari G, Sgherri G, Campese VM. Diurnal variations of blood pressure and microalbuminuria in essential hypertension. Am J Hypertens 1994; 7:23-29.
36. Kannel WB, Castelli WP, Gordon T. Cholesterol in the prediction of atherosclerotic disease. New perspectives based on the Framingham Study. Ann Intern Med 1979; 90:85-91.
37. Gordon T, Kannel WB, Castelli WP, Dawber TR. Lipoproteins, cardiovascular disease and death. The Framingham Study. Arch Intern Med 1981; 141:1128-1131.
38. Campese VM, Bianchi S, Bigazzi R. Hypertension, hyperlipidemia and microalbuminuria. Contrib Nephrol 1997; 120:11-21.
39. Keane WF, Mulcahy WS, Kasiske BL, Kim Y, O'Donnell MP. Hyperlipidemia and progressive renal disease. Kidney Int 1991; 39 (suppl 31):S41-S48.
40. Kasiske BL, O'Donnell MP, Cowardin W, Keane WF. Lipids and the kidney. Hypertension 1990; 15:443-450.
41. Klahr S, Schreiner G, Ichikawa I. The progression of renal disease. New Engl J Med 1988; 318:1657-1666.
42. Fauvel JP, Hadj-Aissa A, Laville M, Fadat G, Labeeuw M, Zech P, et al. Microalbuminuria in normotensives with genetic risk of hypertension. Nephron 1991; 57:375-376.
43. Grunfeld B, Perelstein E, Simsolo R, Gimenez M, Romero JC. Renal functional reserve and microalbuminuria in offspring of hypertensive parents. Hypertension 1980; 3:257-261.
44. Keane WF, Peter JVS, Kasiske BL. Is the aggressive management of hyperlipidemia in nephrotic syndrome mandatory? Kidney Int 1992; 42 (suppl 38): S134-S141.
45. Kaysen GA. Hyperlipidemia of the nephrotic syndrome. Kidney Int 1991; 39 (suppl 31):S8-S15.
46. Newmark SR, Anderson CF, Donadio JV, Ellefson RD. Lipoprotein profiles in adult nephrotics. Mayo Clin Proc 1975; 50:359-366.
47. Karȧdi I, Romics L, Pȧlos G, Domȧn J, Kaszȧs I, Hesz A, et al., Lp(a) lipoprotein concentration in serum of patients with heavy proteinuria of different origin. Clin Chem 1989; 10:2121-2123.
48. Takegoshi T, Haba T, Hirai J, Kitoh C, Saga T, Yamazaki Y, et al. Alterations of lipoprotein(a) in patients iwth diabetic nephropathy. Atherosclerosis 1990; 83:99-100.
49. Metcalf PA, Baker JR, Scragg RK, Dryson E, Scott AJ, Wild CJ. Albuminuria in people at least 40 years old: effect of alcohol consumption, regular exercise, and cigarette smoking. Clin Chem 1993; 39:1793-1797.
50. Perera G. Hypertensive vascular disease: description and natural history. J Chron Dis 1955; 1:33-42.
51. Rosansky SJ. Hypertensive nephropathy: re-examined. Kidney Int 1991; 24:1-8.
52. Mroczek WJ, Davidov M, Gavrilovich L, Finnerty FA. The value of aggressive therapy in the hypertensive patients with azotemia. Circulation 1969; 15:893-904.
53. Mandani BH, Lim VS, Mahurfcar SD, Katz M, Dunea A. Recovery from prolonged renal failure in patients with accelerated hypertension. N Engl J Med 1974; 291:1343-1344.
54. US Renal Data System annual data report. Incidence and prevalence of ESRD. Am J Kidney Dis 1996; 28 (suppl 2):S34-S47.
55. Brunner FP, Selwood NH, on behalf of EDTA Registration Committee. Profile of patients on RRT in Europe and death rates due to major causes of death groups. Kidney Int 1992, 4 (suppl 38):S4-S15.
56. Rosansky SJ, Hoover DR, King L, Gibson J. The association of blood pressure levels and change in renal function in hypertensive and nonhypertensive subjects. Arch Intern Med 1990; 151:1280-1287.
57. Tierney WM, McDonald CJ, Luft FC. Renal disease in hypertensive adults: effect of race and type II diabetes mellitus. Am J Kidney Dis 1989; 13:489-493.
58. Rostand SG, Brown G, Kirk KA, Rutsky EA, Dustan HP. Renal insufficiency in treated essential hypertension. N Engl J Med 1989; 320:684-688.
59. Shulman NB, Ford CE, Hall WD, Blaufox MD, Simon D, Langford HG, et al. Prognostic value of serum creatinine and the effect of treatment of hypertension on the renal function: results from Hypertension Detection and Follow-up Program. Hypertension 1989; 13 (suppl I):180-193.
60. Losito A, Fortunati F, Zampi I, Del Favero A. Impaired functional reserve and albuminuria in essential hypertension. BMJ 1988; 296:1562-1564.
61. Schmieder RE, Veelken R, Gatzka CD, Ruddel H, Schachinger H. Predictors for hypertensive nephropathy: results of a 6-year follow-up in essential hypertension. J Hypertens 1994; 13:357-365.
62. Ruilope LM, Campo C, Rodriguez-Artalejo F, Lahera V, Garcia-Robles R, Rodicio JL. Blood pressure and renal function: therapeutic implications. J Hypertens 1996; 14:1259-1263
63. Ljungman S, Wikstrand J, Hartford M, Aurell M, Lindstedt G, Berglund G. Effects of long-term antihypertensive treatment and aging on renal function and albumin excretion in primary hypertension. Am J Hypertens 1993; 6:554-563.
64. Bianchi S, Bigazzi R, Baldari G, Campese VM. Microalbuminuria in patients with essential hypertension: effects of several antihypertensive drugs. Am J Med 1992; 93:525-528.
65. Bigazzi R, Bianchi S, Baldari D, Sgherri G, Baldari G, Campese VM. Long-term effects of a converting enzyme inhibitor and a calcium channel blocker on urinary albumin excretion in patients with essential hypertension. Am J Hypertens 1992; 6:108-113.
66. Erley CM, Haefele U, Heyne N, Braun N, Risler T. Microalbuminuria in essential hypertension. Reduction by different antihypertensive drugs. Hypertension 1993; 21:810-815.
67. Cannon PJ, Stason WB, Demartini FE, Sommers SC, Laragh JH. Hyperuricemia in primary and renal hypertension. N Engl J Med 1966; 275:457-464.
68. Simon NM, Smucker JE, O'Conor J Jr, delGreco F. Differential uric acid excretion in essential and renal hypertension. Circulation 1969; 39:121-125.
69. Ferris TF, Gorden P. Effect of angiotensin and norepinephrine upon urate clearance in man. Am J Med 1968; 44:359-365.
70. Messerli FH, Frohlich ED, Dreslinski GR, Suarez DH, Aristimuno GG. Serum uric acid in essential hypertension: an indicator of renal vascular involvement. Ann Intern Med 1980; 93:817-821.