Free radicals in pathogenesis: Health-promoting functions of plant- and milk-derived antioxidants

Monatsschrift fur Kinderheilkunde

Volumn 146, Issue 8 SUPPL. 1, 1998, Pages

  Hippeli, Susanne ^a   Rohnert, Ute ^a   Koske, Dagmar ^a   Elstner, E F ^a   Schneider, W ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Fa Steigerwald   (Germany)

Author keywords

Antioxidants; Food additives; Phenolics; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; ASCORBATE OXIDASE; CATALASE; ETHYLENE; FREE RADICAL; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROXYLAMINE; HYPOCHLOROUS ACID; NATURAL PRODUCT; OXIDOREDUCTASE; OXYGEN; PEROXIDASE; PEROXYNITRITE; PHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; SALICYLIC ACID; SALIX EXTRACT; SCAVENGER; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

APOPTOSIS; CELL COMPARTMENTALIZATION; CONFERENCE PAPER; DETOXIFICATION; HEALTH PROMOTION; LYSIS; MILK; NECROSIS; OXIDATIVE STRESS; PATHOGENESIS; PLANT;

EID: 0031679457     PISSN: 00269298     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00014768     Document Type: Conference Paper

References (34)

1. Abu-Amsha R, Croft KD, Puddey IB, Proudfood JM, Beilin U (1996) Phenolic content of various beverages determines the extent of inhibition of human serum and low densitiy lipoprotein oxidation in vitro: identification and mechanism of action of some cinnamic acid derivatives from red wine. Clin Sci (Colch) 91:449-458
2. Andriambelosom E, Kleschyov AL, Muller B, Beretz A, Stoclet C, Andriantsitohaina R (1997) Nitric oxide production and endothelium-dependent vasorelaxation induced by wine polyphenols in rat aorta. Brit J Pharmacol 120:1053-1058
3. Bors W, Saran M (1987) Radical scavenging by flavonoid antioxidants. Free Rad Res 2:289-294
4. Bors W, Saran M, Elstner EF (1992) Screening for plant antioxidants. In: Linskens HF, Jackson JF (eds) Modern methods of plant analysis, vol 13. Plant toxin analysis. Springer, Berlin Heidelberg New York, pp 277-295
5. Buettner G (1993) The pecking order of free radicals and antioxidants: lipid peroxidation, α-tocopherol and ascorbate. Arch Biochem Biophys 300:535-543
6. Candeias LP, Patel KB, Stratford WRL, Wardman P (1993) Free hydroxyl radicals are formed on reaction between the neutrophil-derived species superoxide ion and hypochlorous add. FEBS Lett 333:151-153
7. Ciba Foundation Symposium 65 (1979) Oxygen free radicals and tissue damage. Excerpta Medica, Amsterdam
8. Decker EA (1995) The role of phenolics, conjugated linoleic acid, carnosine and pyrroloquinoline quinone as nonessential dietary antioxidants. Nutr Rev 53:49-58
9. Durner J, Shah J, Klessig DF (1997) Salicylic acid and disease reistance in plants. Trends in Plant Sci 2:266-274
10. Elstner EF (1987) Metabolism of activated oxygen species. In: The biochemistry of plants, vol 11. Academic Press, 253-315
11. Elstner EF (1990) Der Sauerstoff - Biochemie Biologie Medizin. Bl-Wissenschaftsverlag, Mannheim
12. Elstner EF (1991) Oxygen radicals biochemical basis for their efficacy. Klin Wochenschr 69:949-956
13. Elstner EF (1991) Mechanisms of oxygen activation in different compartments of plant cells. In: Pell E, Steffen K (eds) Active oxygen/oxidative stress and plant metabolism. American Society of Plant Physiologists, Current Topics in Plant Physiology 6:13-25
14. Elstner EF (1993) Sauerstoffabhängige Erkrankungen und Therapien. Bl-Wissenschaftsverlag, Mannheim
15. Elstner EF, Heupel A (1976) Inhibition of nitrite formation from hydroxylammonium chloride: a simple assay for superoxide dismutase. Anal Biochem 70:616-620
16. Elstner EF, Kleber E (1990) Radical scavenger properties of leucocyanidine. In: Das NP (ed) Flavonoids in biology and medicine III. Current issues in flavonoid research. National University of Singapore, Singapore, pp 227-235
17. Gotoh N, Noguchi N, Tsuchiya Y, Morita K, Sakai H, Niki E (1996) Inhibition of oxidation of low density lipoprotein by vitamin E and related compounds. Free Rad Res 24:23-124
18. Halliwell S (1996) Antioxidants in human health and disease. An Rev Nutr 16:33-50
19. Halliwell B, Gutteridge JMC (1989) Free radicals in biology and medicine. Clarendon Press, Oxford
20. Hayase F, Kato H (1984) Antioxidative components of sweet potatoes. J Nutr Sci Vitaminol (Tokyo) 30:37-46
21. Hippeli S, Elstner EF (1997) OH-radical-type reactive oxygen species: a short review on the mechanisms of OH-radical and peroxynitrite toxicity. Z Naturforsch. 52c:555-563
22. Hippeli S, Rohnert U, Koske D, Elstner EF (1997) OH-radical-type reactive oxygen species derived from superoxide and nitric oxide: a sensitive method for their determination and differentiation. Z Naturforsch 52c 564-570
23. Kontush A, Hubner C, Finckh B, Kohlschutter A, Beisiegl U (1995) Antioxidative activity of ubiquinol-10 at physiological concentrations in human low density lipoprotein. Biochim Biophys Acta 1258:177-187
24. Kruedener Sv, Schempp H, Elstner EF (1995) Gas chromatographic differentiation between myeloperoxidase activity and Fenton-type oxidants. Free Rad Biol Med 19:141-146
25. Laughton MJ, Halliwell B, Evans PJ, Hoult JR (1989) Antioxidant and prooxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA. Biochem Pharmacol 38:2859-2865
26. Lefer DJ, Scalia R, Campbeil B, Nossuli T, Hayward R, Salamon M, Grayson J, Lefer AM (1997) Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects agains ischemia-reperfusion injury in rats. J Clin Invest 99:684-691
27. Mcran JF, Klucas RV, Grayer RJ, Abian J, Becana M (1997) Complexes of iron with phenolic compounds from soybean nodules and other legume tissues: prooxidant and antioxidant properties. Free Rad Biol Med 22:861-870
28. Neuzil J, Stocker R (1994) Free and albumin-bound bilirubin are efficient co-antioxidants for α-tocopherol, inhibiting plasma and low densitiy lipoprotein lipid peroxidation. J Biol Chem 269:16712-16719
29. Pryor WA, Squadrito GL (1995) The chemistry of peroxynitrite: a product from the reaction of nitric oxide and superoxide. Am J Physiol 268:L599-L722
30. Rakotoanson DA, Gressier B, Trotin F, Brunet C, Dine T, Luyckx M, Vasseur J, Cazin M, Cazin JC, Pinkas M (1997) Antioxidant activities of polyphenolic extracts from flowers, in vitro cultures and cell suspension cultures of Crataegus monogyna. Pharmazie 52:60-64
31. Schiussel EH, Elstner EF (1996) Desialylation of low density lipoprotein - metabolic function versus oxidative damage? Z Naturforsch 51:395-400
32. Sies H (ed) 1985, 1991) Oxidative stress oxidants and antioxidants. Academic Press, London
33. Stadler RH, Markovic J, Turesky RJ (1995) In vitro anti- and prooxidative effects of natural phenolics. Biol Trace Elem Res 47:299-305
34. Thomas SR, Neuzil J, Stocker R (1996) Cosupplementation with coenzyme Q prevents the prooxidant effect of α-tocopherol and increases the resistance of LDL to transition metal-dependent oxidation initiation. Artenoscier Throm Vasc Biol 16:687-696