Mechanism of maxi-K channel activation by dehydrosoyasaponin-I

Journal of General Physiology

Volumn 112, Issue 4, 1998, Pages 485-501

  Giangiacomo, Kathleen M ^a   Kamassah, Augustus ^b   Harris, Guy ^b   Mcmanus, Owen B ^b  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Calcium activated potassium channel; Ion channel gating; Ion channel pharmacology; Potassium channel agonist

Indexed keywords

DEHYDROSOYASAPONIN I; SOYASAPONIN I; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CATTLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONFORMATION; CONTROLLED STUDY; ELECTRIC POTENTIAL; ION CONDUCTANCE; LIPID BILAYER; MATHEMATICAL ANALYSIS; MEMBRANE POTENTIAL; NONHUMAN; PROTEIN BINDING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AORTA; CALCIUM; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; OLEANOLIC ACID; POTASSIUM CHANNELS; SAPONINS; SARCOLEMMA; TRITERPENES;

EID: 0031671225     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.112.4.485     Document Type: Article

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