p53 Mutations and DNA ploidy in colorectal adenocarcinomas

Analytical Cellular Pathology

Volumn 17, Issue 1, 1998, Pages 1-12

  Campomenosi, Paola ^a   Assereto, Paola ^a   Bogliolo, Massimo ^a   Fronza, Gilberto ^a   Abbondandolo, Angelo ^a,b   Capasso, Antonella ^c   Bellomo, Patrizia F ^c   Monaco, Roberto ^c   Rapallo, Anna ^a   Sciutto, Andrea ^a   Orecchia, Roberto ^a   Geido, Elio ^a   Giaretti, Walter ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c CARDARELLI HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ANEUPLOIDY; ARTICLE; COLON CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN TISSUE; PLOIDY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0031669861     PISSN: 09218912     EISSN: None     Source Type: Journal    
DOI: 10.1155/1998/396371     Document Type: Article

References (43)

1. V.B. Astler and F.A. Coller, The prognostic significance of direct extension of carcinoma of the colon and rectum, Ann Surg. 139 (1954), 846-851.
2. R. Batanian, S.A. Ledbetter, R.K. Wolff, Y. Nakamura, R. White, W.B. Dobyns and D.H. Ledbetter, Rapid diagnosis of Miller-Dieker syndrome and isolated lissencephaly sequence by the polymerase chain reaction, Hum. Genet. 85 (1990), 555-559.
3. F.Z. Bischoff, S.O. Yim, S. Pathak, G. Grant, M.J. Siciliano, B.C. Giovanella, L.C. Strong and M.A. Tainsky, Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization, Cancer Res. 50 (1990), 7979-7984.
4. P.L. Blount, P.C. Galipeau, C.A. Sanchez, K. Neshat, D.S. Levine, J. Yin, H. Suzuki, J.M. Abraham, S.J. Meltzer and B.J. Reid, 17p allelic losses in diploid cells of patients with Barrett's esophagus who develop aneuploidy, Cancer Res. 54 (1994), 2292-2295.
5. J.R. Bos, E.R. Fearon, S.R. Hamilton, M. Verlaan de Vries, J.H. van Boom, A.J. van der Eb and B. Vogelstein, Prevalence of ras gene mutations in human colorectal cancers, Nature 327 (1987), 293-297.
6. G.C. Burmer and L.A. Loeb, Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma, Proc. Natl. Acad. Sci. 86 (1989), 2403-2407.
7. G.C. Burmer, P.S. Rabinovitch, R.C. Haggit, D.A. Crispin, T.A. Brentnall, V.R. Kolli, A.C. Stevens and C.E. Rubin, Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele, Gastroenterology 103 (1992), 1602-1610.
8. A.L. Børresen, E. Hovig, B. Smith-Sörensen, D. Malkin, S. Lystad, T.I. Andersen, J.M. Nesland, K.J. Isselbacher and S.H. Friend, Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations, Proc. Natl. Acad. Sci. 88 (1991), 8405-8409.
9. A. Calugi, P. Eleuteri, D. Cavallo, G. Naso, L. Albonici, M.P. Lombardi, V. Manzari, C. Romanini and R. DeVita, Detection of cellular heterogeneity by DNA ploidy, 17 chromosome and p53 gene in primary carcinoma and metastasis in a case of ovarian cancer, Int. J. Gynecol. Pathol. 15 (1996), 77-81.
10. P. Campomenosi, M. Conio, M. Bogliolo, S. Urbini, P. Assereto, A. Aprile, P. Monti, H. Aste, G. Lapertosa, A. Inga, A. Abbondandolo and G. Fronza, p53 is frequently mutated in Barret's metaplasia of the intestinal type, Cancer Epidemiol. Biomark. Prevent. 5 (1996), 559-565.
11. L.A. Cannon-Albright, M.H. Skolnick, D.T. Bishop, R.G. Lee and R.W. Burt, Common inheritance of susceptibility to colonie adenomatous polyps and associated colorectal cancers, New Engl. J. Med. 319 (1988), 533-537.
12. P.J. Carder, A.H. Wyllie, C.A. Purdie, R.G. Morris, S. White, J. Piris and C.C. Bird, Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer, Oncogene 8 (1993), 1397-1401.
13. P.J. Carder, K.J. Cripps, R. Morris, S. Collins, S. White, C.C. Bird and A.H. Wyllie, Mutation of the p53 gene precedes aneuploid clonal divergence in colorectal carcinoma, Br. J. Cancer 71 (1995), 215-218.
14. Y. Cho, S. Gorina, P.D. Jeffrey and N.P. Pavletich, Crystal structure of p53 tumour suppressor-DNA complex: understanding tumourigenic mutations, Science 265 (1994), 346-355.
15. A. Costa, R. Marasca, B. Valentinis, M. Savarino, A. Faranda, S. Silvestrini and G. Torelli, p53 gene point mutations in relation to p53 nuclear protein accumulation in colorectal cancers, J. Pathol. 176 (1995), 45-53.
16. K.J. Cripps, C.A. Purdie, P.J. Carder, S. White, K. Komine, C.C. Bird and A.H. Wyllie, A study of stabilization of p53 versus point mutation in colorectal carcinoma, Oncogene 9 (1994), 2734-2743.
17. Y. Cross, C.A. Sanchez, C.A. Morgan, M.K. Schimke, S. Ramel, R.L. Idzerda, W.H. Raskind and B.J. Reid, A p53-dependent mouse spindle checkpoint, Science 267 (1995), 1353-1355.
18. F. D'Agostini, G. Fronza, P. Campomenosi, A. Izzotti, G.L. Petrilli, A. Abbondandolo and S. De Flora, Cancer biomarkers in human atherosclerotic lesions. No evidence of p53 involvement, Cancer Epidemiol. Biomark. Prevent. 4 (1995), 111-115.
19. A. Di Vinci, E. Infusini, C. Peveri, M. Risio, RP. Rossini and W. Giaretti, Deletions at chromosome 1p by fluorescence in situ hybridization are an early event in human colorectal tumourigenesis, Gastroenterology 111 (1996), 102-107.
20. A. Di Vinci, E. Infusini, C. Peveri, A. Sciutto, M. Risio, F.P. Rossini and W. Giaretti, Correlation between 1p deletions and aneusomy in human colorectal adenomas, Int. J. Cancer 73 (1997), 1-6.
21. E.R. Fearon and B. Vogelstein, A genetic model for colorectal tumourigenesis, Cell 61 (1990), 759-767.
22. R. Fishel, M.K. Lescoe, M.S.R. Rao, N.G. Copeland, N.A. Jenkins, J. Garber, M. Kane and R. Kolodner, The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer, Cell 75 (1993), 1027-1038.
23. J.L. Fleiss, Statistical Methods for Rates and Proportions, 2nd edn, Wiley, New York, 1988.
24. W. Giaretti, A model of DNA aneuploidization and evolution in colorectal cancer, Lab. Invest. 71 (1994), 904-910.
25. W. Giaretti, N. Pujic, A. Rapallo, S. Nigro, A. Di Vinci, E. Geido and M. Risio, K-ras2 G-C and G-T transversions correlate with DNA aneuploidy in colorectal adenomas, Gastroenterology 108 (1995), 1040-1047.
26. W. Giaretti, W.R. Monaco, N. Pujic, A. Rapallo, S. Nigro and E. Geido, Intratumour heterogeneity of K-ras2 mutations in colorectal adenocarcinomas. Association with degree of DNA aneuploidy and S-phase fraction, Am. J. Pathol. 149 (1996), 237-245.
27. M.S. Greenblatt, W.P. Bennett, M. Hollstein and C.C. Harris, Mutations in the p53 tumour suppressor gene: clues to cancer etiology and molecular pathogenesis, Cancer Res. 54 (1994), 4855-4878.
28. M. Hollstein, B. Shomer, M. Greenblatt, T. Soussi, E. Hovig, R. Montesano and C.C. Harris, Somatic point mutations in the p53 gene of human tumours and cell lines: updated compilation, Nucl. Acids Res. 24 (1996), 141-146.
29. D. Lane, p53, the guardian of the genome, Nature 358 (1992), 15-16.
30. F.S. Leach, N.C. Nicolaides, N. Papadopoulos, B. Liu, J. Jen, R. Parson, P. Peltomäki, P. Sistonen, L.A. Aaltonen, M. Nyström-Lahti, X.Y. Guan, J. Zhang, P.S. Meltzer, J.W. Yu, F.T. Kao, D.J. Chen, K.M. Cerosaletti, R.E.K. Fournier, S. Todd, T. Lewis, R.J. Leach, S.L. Naylor, J. Weissenbach, J.P. Mecklin, H. Järvinen, G.M. Petersen, S.R. Hamilton, J. Green, J. Jass, P. Watson, H.T. Lynch, J.M. Trent, A. de la Chapelle, K.W. Kinzler and B. Vogelstein, Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer, Cell 75 (1993), 1215-1225.
31. G.I. Meling, R.A. Lothe, A.L. Børresen, C. Graue, S. Hauge, O.P.F. Clausen and T.O. Rognum, The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables, Br. J. Cancer 67 (1993), 93-98.
32. B.C. Morson and L.H. Sobin, Histological typing of intestinal tumours, in: International Histological Classification of Tumours, WHO, Geneva, 1976, pp. 14-35.
33. T. Muto, H.J.R. Bussey and B.C. Morson, The evolution of cancer of the colon and rectum, Cancer 36 (1975), 2251-2270.
34. K. Neshat, C.A. Sanchez, P.C. Galipeau, P.L. Blount, D.S. Levine, G. Joslyn and B.J. Reid, p53 mutations in Barrett's adenocarcinoma and high-grade dysplasia, Gastroenterology 106 (1994), 1589-1595.
35. N.C. Nicolaides, N. Papadopoulos, B. Liu, Y.F. Wei, K.C. Carter, S.M. Ruben, C.A. Rosen, W.A. Haseltine, R.D. Fleischmann, C.M. Fraser, M.D. Adams, J.C. Venter, M.G. Dunlop, S.R. Hamilton, G.M. Petersen, A. de la Chapelle, B. Vogelstein and K.W. Kinzler, Mutations of two PMS homologues in hereditary nonpolyposis colon cancer, Nature 371 (1994), 75-80.
36. J.M. Nigro, S.J. Baker, A.C. Preisinger, J.M. Jessup, R. Hostetter, K. Cleary, S.H. Bigner, N. Davidson, S. Baylin, P. Devilee, T. Glover, RS. Collins, A. Weston, R. Modali, C.C. Harris and B. Vogelstein, Mutations in the p53 gene occur in diverse tumour types, Nature 342 (1989), 705-708.
37. S. Nigro, E. Geido, E. Infusini, R. Orecchia and W. Giaretti, Transfection of human mutated K-ras in mouse NIH-3T3 cells is associated with increased coloning efficiency and DNA aneuploidization, Int. J. Cancer 67 (1996), 871-875.
38. C. Schmutte, A.S. Yang, R.W. Beart and P.A. Jones, Base excision repair of U : G mismatches at a mutational hotspot in the p53 gene is more efficient than base excision repair of T: G mismatches in extracts of human colon tumours, Cancer Res. 55 (1995), 3742-3746.
39. V.C. Sheffield, D.R. Cox, L.S. Lerman and R.M. Myers, Attachement of a 40-base-pair G+C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes, Proc. Natl. Acad. Sci. 86 (1989), 232-236.
40. E. Solomon, R. Voss, V. Hall, W.F. Bodmer, J.R. Jass, A.J. Jeffreys, F.C. Lucibello, I. Patel and S.H. Rider, Chromosome 5 allele loss in human colorectal carcinomas, Nature 328 (1987), 616-619.
41. J.P. Sugarbaker, L.L. Gunderson and R.E. Wittes, Colorectal cancer, in: Cancer: Principles and Practices of Oncology, 2nd edn, J.B. Lippincott, Philadelphia, PA, 1985, pp. 800-803.
42. B. Vogelstein, E.R. Fearon, S.R. Hamilton, S.E. Kern, A.C. Preisinger, B.A.M. Leppert, Y. Nakamura, R. White, A.M.M. Smits and J.L. Bos, Genetic alterations during colorectal-tumour development, New Engl. J. Med. 319 (1988), 525-532.
43. B. Vogelstein, E.R. Fearon, S.E. Kern, S.R. Hamilton, A.C. Preisinger, Y. Nakamura and R. White, Allclotype of colorectal carcinomas, Science 244 (1989), 207-211.