p53 is frequently mutated in Barrett's metaplasia of the intestinal type

Cancer Epidemiology Biomarkers and Prevention

Volumn 5, Issue 7, 1996, Pages 559-565

  Campomcnosi, Paola ^a   Conio, Massinio ^a   Bogliolo, Massimo ^a   Urbini, Stefania ^a   Assereto, Paola ^a   Aprile, Anna ^a   Monti, Paola ^a   Aste, Hugo ^a   Lapertosa, Gabriella ^b   Inga, Alberto ^a   Abbondandolo, Angelo ^a,b   Fronza, Gilberto ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CANCER SUSCEPTIBILITY; CELL CYCLE; CLINICAL ARTICLE; FEMALE; GASTROESOPHAGEAL REFLUX; GENE MUTATION; HETEROZYGOSITY; HUMAN; MALE; METAPLASIA; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; STOMACH CANCER;

ADULT; AGED; AGED, 80 AND OVER; BARRETT ESOPHAGUS; BIOPSY; CELL TRANSFORMATION, NEOPLASTIC; CULTURE TECHNIQUES; ESOPHAGEAL NEOPLASMS; ESOPHAGOSCOPY; FEMALE; GENES, P53; GENES, RAS; HUMANS; INTESTINES; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS; SENSITIVITY AND SPECIFICITY;

EID: 15844401784     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Spechler, S. J., and Goyal, R. K. Barrett's esophagus. N. Engl. J. Med., 315: 362-371, 1986.
2. Spechler, S. J. Barrett's Esophagus. Semin. Oncol., 21: 431-437, 1994.
3. Wright, T. A., and Kingsnorth, A. N. Barrett's oesophagus and markers of malignant potential. Eur. J. Gastroenterol. Hepatol., 6: 656-662, 1994.
4. Levine, D. S. Barrett's oesophagus and p53. Lancet, 344: 212-213, 1994.
5. Rabinovitch, P. S., Reid, B. J., Haggitt, R. C., Norwood, T. H., and Rubin, C. E. Progression to cancer in Barrett's esophagus is associated with genomic instability. Lab. Invest., 60: 65-71, 1988.
6. Reid, B. J., Blount, P. L., Rubin, C. E., Levine, D. S., Haggitt, R. C., and Rabinovitch, P. S. Flow-cytometric and histological progression to malignancy in Barrett's esophagus: prospective endoscopie surveillance of a cohort. Gastroenterology, 102: 1212-1219, 1992.
7. Vogelstein, B., and Kinzler, K. W. p53 function and dysfunction. Cell, 70: 523-526, 1992.
8. Blount, P. L., Galipeau, P. C., Sanchez, C. A., Neshat, K., Levine, D. S., Yin, J., Suzuki, H., Abraham, J. M., Meltzer, S. J., and Reid, B. J. 17p allelic losses in diploid cells of patients with Barrett's esophagus who develop aneuploidy. Cancer Res., 54: 2292-2295, 1994.
9. Neshat, K., Sanchez, C. A., Galipeau, P. C., Blount, P. L., Levine, D. S., Joslyn, G., and Reid, B. J. p53 mutations in Barrett's adenocarcinoma and high-grade dysplasia. Gastroenterology, 106: 1589-1595, 1994.
10. Cross, S. M., Sanchez, C. A., Morgan, C. A., Schimke, M. K., Ramel, S., Idzerda, R. L., Raskind, W. H., and Reid, B. J. A p53-dependent mouse spindle checkpoint. Science (Washington DC), 267: 1353-1356, 1995.
11. Greenblatt, M.S., Bennett, W. P., Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855-4878, 1994.
12. Casson, A. G., Mukhopadhyay, T., Cleary, K. R., Ro, J. Y., Levin, B., and Roth, J. A. p53 gene mutations in Barrett's epithelium and esophageal cancer. Cancer Res., 51: 4495-4499, 1991.
13. Hamelin, R., Fléjou, J-F., Muzeau, F., Potet, F., Laurent-Puig, P., Fékété, F., and Thomas, G. TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus. Gastroenterology, 107: 1012-1018, 1994.
14. Ramel, S., Reid, B. J., Sanchez, C. A., Blount, P. L., Levine, D. S., Neshat, K., Haggitt, R. C., Dean, P. J., Thor, K., and Rabinovitch, P. S. Evaluation of p53 protein expression in Barrett's esophagus by two-parameter flow cytometry. Gastroenterology, 102: 1220-1228, 1992.
15. Fléjou, J-F., Potet, F., Muzeau, F., Le Pelletier, F., Fékété, F., and Hénin, D. Overexpression of p53 protein in Barrett's syndrome with malignant transformation. J. Clin. Pathol., 46: 330-333, 1993.
16. Younes, M., Lebovitz, R. M., Lechago, L. V., and Lechago, J. p53 protein accumulation in Barrett's metaplasia, dysplasia, and carcinoma: a follow-up study. Gastroenterology, 105: 1637-1642, 1993.
17. Symmans, P. J., Linehan, M., Brito, M. J., and Filipe, M. I. p53 expression in Barrett's oesophagus, dysplasia, and adenocarcinoma using antibody DO-7. J. Pathol., 73: 221-226, 1994.
18. Krishnadath, K. K., Tilanus, H. W., van Blankenstein, M., Bosman, F. T., and Mulder, A. H. Accumulation of p53 protein in normal, dysplastic and neoplastic Barrett's oesophagus. J. Pathol., 175: 175-180, 1995.
19. Bourne, H. R., Sanders, D. A., and McCormick, F. The GTPase superfamily, conserved structure and molecular mechanism. Nature (Lond.), 349: 117-127, 1991.
20. Bogusky, M. S., and McCormick, F. Proteins regulating ras and its relatives. Nature (Lond.), 366: 643-654, 1993.
21. Bos, J. L. Ras oncogenes in human cancer: a review. Cancer Res., 49: 4682-4689, 1989.
22. Jankowski, J., Coghill, G., Hopwood, D., and Wormsley, K. G. Oncogenes and onco-suppressor gene in adenocarcinoma of the oesophagus. Gut, 33: 1033-1038, 1992.
23. Gruppo Operative per lo Studio delle Precancerosi dell'Esofago (GOSPE). Barrett's esophagus: epidemiological and clinical results of a multicentric survey. Int. J. Cancer, 48: 364-368, 1991.
24. D'Agostini, F., Fronza, G., Campomenosi, P., Izzotti, A., Petrilli, G. L., Abbondandolo, A., and De Flora, S. Cancer biomarkers in human atherosclerotic lesions: no evidence of p53 involvement. Cancer Epidemiol., Biomarkers & Prev., 4: 111-115, 1995.
25. Pellegata, N. S., Sessa, F., Renault, B., Bonato, M., Leone, B. E., Solcia, E., and Ranzani, G. N. K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. Cancer Res., 54: 1556-1560, 1994.
26. Schmidt, H. G., Riddel, R. H., Walter, B., Skinner, D. B., and Riemann, J. F. Dysplasia in Barrett's esophagus. J. Cancer Res. Clin. Oncol., 110: 145-152, 1985.
27. Batanian, J. R., Ledbetter, S. A., Wolff, R. K., Nakamura, Y., White, R., Dobyns, W. B., and Ledbetter, D. H. Rapid diagnosis of Miller-Dieker syndrome and isolated lissencephaly sequence by the polymerase chain reaction. Hum. Genet., 85: 555-559, 1990.
28. Serra, A., Gaidano, G. L., Revello, D., Guerrasio, A., Ballerini, P., Dalla Favera, R., and Saglio, G. A new TaqI polymorphism in the p53 gene. Nucleic Acids Res., 20: 928, 1992.
29. Shapiro, M. V., and Senapathy, P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res., 15: 7155-7174, 1987.
30. Ferec, C., Audrezet, M-P., Mercier, B., and Robaszkiewicz, M. TP53 gene alterations during neoplastic progression of Barrett's mucosa. Gastronterol. Clin. Biol., 18: D46-D51, 1994.
31. Hardwick, R. H., Shepherd, N. A., Moorghen, M., Newcomb, P. V., and Alderson, D. Adenocarcinoma arising in Barrett's oesophagus: evidence for the participation of p53 dysfunction in the dysplasia/carcinoma sequence. Gut, 35: 764-768, 1994.
32. Soussi, T., Caron de Fromentel, C., and May, P. Structural aspects of the p53 protein in relation to gene evolution. Oncogene, 5: 945-952, 1990.
33. Kern, S. E., Pietenpol, J. A., Thiagalingam, S., Seymour, A., Kinzler, K. W., and Vogelstein, B. Oncogenic forms of p53 inhibit p53 regulated gene expression. Science (Washington DC), 256: 827-830, 1992.
34. Hachiya, M., Chumakov, A., Miller, C. W., Akashi, M., Said, J., and Koeffler, H. P. Mutant p53 proteins behave in a dominant, negative fashion in vivo. Anticancer Res., 14: 1853-1860, 1994.
35. Meltzer, S. J., Yin, J., Huang, Y., McDaniel, T. K., Newkirk, C., Iseri, O., Vogelstein, B., and Resau, J. H. Reduction to homozygoshy involving p53 in esophageal cancers demonstrated by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA, 88: 4976-4980, 1991.
36. Reid, B. J., Haggitt, R. C., Rubin, C. E., and Rabinovitch, P. S. Barrett's esophagus. Correlation between flow cytometry and histology in detection of patients at risk for adenocarcinoma. Gastroenterology, 93: 1-11, 1987.
37. Hurlimann, J., and Saraga, E. P. Expression of p53 protein in gastric carcinomas: association with histologic type and prognosis. Am. J. Surg. Pathol., 18: 1247-1253, 1994.
38. Ranzani, G. N., Luinetti, O., Padovan, L. S., Calistri, D., Renault, B., Burrel, M., Amadori, D., Fiocca, R., and Solcia, E. p53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type.
39. Cerutti, P. A. Oxy-radicals and cancer. Lancet, 344: 862-863, 1994.
40. Grisham, M. B. Oxidants and free radicals in inflammatory bowel disease. Lancet, 344: 859-861, 1994.
41. McDonnell, W. M., Scheiman, J. M., and Traber, P. G. Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. Gastroenterology, 103: 1509-1516, 1992.
42. Vogelstein, B., and Kinzler, K. W. Carcinogens leave fingerprints. Nature (Lond.), 355: 209-210, 1992.
43. Imazeki, F., Omata, M., Nose, H., Ohto, M., and Isono, K. p53 gene mutations in gastric and esophaseal cancers. Gastroenterology, 103: 892-896, 1992.
44. Renault, B., Van Der Broek, M., Fodde, R., Wijnen, J., Pellegata, N. S., Amadori, D., Meera Khan, P., and Ranzani, G. N. Base transitions are the most frequent genetic changes at p53 in gastric cancer. Cancer Res., 53: 2614-2617, 1993.
45. Uchino, S., Noguchi, M., Ochiai, A., Saito, T., Kobayashi, M., and Hirohashi, S. p53 mutations in gastric cancer: a genetic model for carcinogenesis is common to gastric and colorectal cancer. Int. J. Cancer, 54: 759-764, 1993.
46. Tornaletti, S., and Pfeifer, G. P. Complete and tissue independent methylation of CpG sites in the p53 gene: implications for mutations in human cancers. Oncogene, 10: 1493-1499, 1995.
47. Lindahl, T. Instability and decay of the primary structure of DNA. Nature (Lond.), 562: 709-715, 1993.
48. Levi, F., Ollyo, J. B., La Vecchia, C, Boyle, P., Monnier, P., and Savary, M. The consumption of tobacco, alcohol, and the risk of adenocarcinoma in Barrett's oesophagus. Int. J. Cancer, 45: 852-854, 1990.
49. Gray, M. R., Donnelly, R. J., and Kingsnorth, A. N. The role of smoking and alcohol in metaplasia and cancer risk in Barrett's columnar-lined oesophagus. Gut, 34: 727-731, 1993.
50. Menke-Pluymers, M. B. E., Hop, W. C. J., Dees, J., van Blankenstein, M., and Tilanus, H. W. The Rotterdam esophageal tumor study group. Risk factors for the development of an adenocarcinoma in columnar-lined (Barrett) esophagus. Cancer (Phila.), 72: 1155-1158, 1993.
51. Suzuki, H., Takahashi, T., Kuroishi, T., Suyama, M., Ariyoshi, Y., Takahashi, T., and Ueda, R. p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. Cancer Res., 52: 734-736, 1992.