Micronucleus formation in human amnion cells after exposure to 50 Hz MF applied horizontally and vertically

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 418, Issue 2-3, 1998, Pages 101-111

  Simko M ^a   Kriehuber, R ^a   Lange, S ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Amniotic fluid cell (AFC cell); Extremely low frequency electromagnetic field (ELF EMF); Genotoxic effect; Horizontal or vertical magnetic field; Inhibition of DNA repair; Micronucleus formation; Paracetamol

Indexed keywords

PARACETAMOL;

AMNION CELL; AMNION FLUID; ARTICLE; CONTROLLED STUDY; DNA REPAIR; ELECTROMAGNETIC FIELD; GENOTOXICITY; HUMAN; HUMAN CELL; MAGNETIC FIELD; MICRONUCLEUS; PRIORITY JOURNAL;

ACETAMINOPHEN; AMNION; ANALGESICS, NON-NARCOTIC; BISBENZIMIDE; CELLS, CULTURED; DNA LIGASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROMAGNETIC FIELDS; FLUORESCENT DYES; HUMANS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MICROSCOPY, FLUORESCENCE;

HELIOTHIS ZEA VIRUS 1;

EID: 0031669820     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00116-8     Document Type: Article

References (41)

1. Wertheimer N., Leeper E. Electrical wiring configurations and childhood cancer. Am. J. Epidemiol. 109:1979;273-284.
2. Tomenius L. 50-Hz electromagnetic environment and the incidence of childhood tumors in Stockholm County. Bioelectromagnetics. 7:1986;191-207.
3. Savitz D.A., Wachtel H., Barnes F.A., John E.M., Tvrdik J.G. Case-control study of childhood cancer and exposure to 60 Hertz magnetic fields. Am. J. Epidemiol. 128:1988;21-38.
4. Washburn E.P., Orza M.J., Berlin J.A., Nicholson W.J., Todd A.C., Frumkin H., Chalmers T.C. Residential proximity to electricity transmission and distribution equipment and risk of childhood leukemia, childhood lymphoma, and childhood nervous system tumors: systematic review, evaluation, and meta-analysis. Cancer Causes and Control. 5:1994;299-309.
5. McCann J., Dietrich F., Rafferty C., Martin A.O. A critical review of the genotoxic potential of electric and magnetic fields. Mutation Res. 297:1993;61-95.
6. Murphy J.C., Kaden D.A., Warren J., Sivak A. International commission for protection against environmental mutagens and carcinogens. Power frequency electric and magnetic fields: a review of genetic toxicology. Mutation Res. 296:1993;221-240.
7. Moulder J.E., Foster K.R. Biological effects of power-frequency fields as they relate to carcinogenesis. Proc. Soc. Exp. Biol. Med. 209:1995;309-324.
8. Liboff A.R., Williams T. Jr., Strong D.M., Wistar R. Jr. Time-varying magnetic fields: effect on DNA synthesis. Science. 223:1984;818-820.
9. Goodman R., Shirley-Henderson A. Exposure of cells to extremely low-frequency electromagnetic fields: relationship to malignancy? Cancer Cells. 2:1990;355-359.
10. R. Goodman, M. Blank, H. Lin, L. Soo, D. Weibrot, A.S. Henderson, Increased levels of HSP70 transcripts are induced when cells are exposed to low frequency electromagnetic field, 16th Annual Meeting BEMS, 1994, pp. 52-53.
11. Scaiano J.C., Mohtat N., Cozens F.L., McLean J., Thansandote A. Application of the radical pair mechanism to free radicals in organized systems: can the effects of 60 Hz be predicted from studies under static fields? Bioelectromagnetics. 15:1994;549-554.
12. G. Katsir, A.H. Parola, 1998, The enhanced cell proloferation caused by sinusoidaly varying magnetic field is suppresed by radical scavengers, Twentieth Annual Meeting of the Bioelectromagnetics Society, St. Pete Beach, FL, USA, June, 1998, p. 132.
13. Walleczek J. Electromagnetic field effects on cells of the immune system: the role of calcium signalling. FASEB J. 6:1992;3177-3185.
14. Luben R.A., Cain C.D., Chen M.C., Rosen D.M., Adey W.R. Effects of electromagnetic stimuli on bone and bone cells in vitro: inhibition of responses to parathyroid hormone by low-energy low-frequency fields. Proc. Natl. Acad. Sci. U.S.A. 79:1982;4180-4184.
15. R.A. Luben, Effects of low-energy electromagnetic fields (EMF) on signal transduction by G protein-linked receptors, in: M. Blank (Ed.), Electricity and Magnetism in Biology and Medicine, San Francisco Press, San Francisco, CA, 1993, pp. 57-62.
16. Uckun F.M., Kurosaki T., Jin J., Jun X., Morgan A., Takata M., Bolen J., Luben R. Exposure of B-lineage lymphoid cells to low energy electromagnetic fields stimulates Lyn kinase. J. Biol. Chem. 270:1995;27666-27670.
17. Holian O., Astumian R.D., Lee R.C., Reyes H.M., Attar B.M., Walter R.J. Protein kinase C activity is altered in HL60 cells exposed to 60 Hz AC electric fields. Bioelectromagnetics. 17:1996;504-509.
18. Merritt R., Purcell C., Stroink G. Uniform magnetic field produced by three, four, and five square coils. Rev. Sci. Instrum. 54:1983;879-882.
19. Brunborg G., Holme J.A., Hongslo J.K. Inhibitory effects of paracetamol on DNA repair in mammalian cells. Mutation Res. 342:1995;157-170.
20. Caputa K., Stuchly M.A. Computer controlled system for producing uniform magnetic fields and its application in biological research. IEEE Transactions on Instrumentation and Measurement. 45:1993;701-709.
21. Caputa K., Jones R., Olivares J.L., Conway P.C., Stuchly M.A., Byus C.V. Advanced system for in vitro exposures to 60 Hz magnetic fields. Proceedings, Department of Energy Contractors Review. 68:1995.
22. Bassen H., Litovitz T., Penafiel M., Meister R. ELF in vitro exposure systems for inducing uniform electric and magnetic fields in cell culture. Bioelectromagnetics. 13:1992;183-198.
23. Countryman P., Heddle J.A. The production of micronuclei from chromosomal aberrations in irradiated cultures of human lymphocytes. Mutation Res. 41:1976;321-332.
24. Simkó M., Kriehuber R., Weiss D.G., Luben R.A. Effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and non-transformed human cell lines. Bioelectromagnetics. 19:1998;85-91.
25. Khalil A.M., Quassem W. Cytogenetic effects of pulsing electromagnetic field on human lymphocytes in vitro: chromosome aberrations, sister-chromatid exchanges. Mutation Res. 247:1991;141-146.
26. Nordenson I., Mild K.H., Andersson G., Sandstrom M. Chromosomal aberrations in human amniotic cells after intermittent exposure to fifty hertz magnetic fields. Bioelectromagnetics. 15:1994;293-301.
27. Rosenthal M., Obe G. Effects of 50-Hz electromagnetic fields on proliferation and on chromosomal alterations in human peripheral lymphocytes untreated or pretreated with chemical mutagens. Mutation Res. 210:1989;329-335.
28. D'Ambrosio G., Massa R., Di Berardino D., Lioi M.B., Scaglione A., Scarfi M.R. Chromosomal aberrations in bovine lymphocytes exposed to 50 Hz electric currents. J. Bioelect. 7:1988;239-245.
29. Lai H., Singh N.P. Acute exposure to a 60 Hz magnetic field increases DNA strand breaks in rat brain cells. Bioelectromagnetics. 18:1997;156-165.
30. Garcia-Sagredo J.M., Parada L.A., Monteagudo J.L. Effect on SCE in human chromosomes in vitro of low-level pulsed magnetic field. Environ. Mol. Mutagen. 16:1990;185-188.
31. Livingston G.K., Witt K.L., Gandhi O.P., Chatterjee I., Roti J.L. Reproductive integrity of mammalian cells exposed to power frequency electromagnetic fields. Environ. Mol. Mutagen. 17:1991;49-58.
32. Scarfi M.R., Bersani F., Cossarizza A., Monti D., Zeni O., Lioi M.B., Franceschetti G., Capri M., Franceschi C. 50 Hz AC sinusoidal electric fields do not exert genotoxic effects (micronucleus formation) in human lymphocytes. Rad. Res. 135:1993;64-68.
33. Fairbairn D.W., O'Neill K.L. The effect of electromagnetic field exposure on the formation of DNA single strand breaks in human cells. Cell. Mol. Biol. (Noisy-le-grand). 40:1994;561-567.
34. Tofani S., Ferrara A., Anglesio L., Gilli G. Evidence for genotoxic effects of resonant ELF magnetic fields. Bioelectrochemistry and Bioenergetics. 36:1995;9-13.
35. Cleary S.F. A review of in vitro studies: low-frequency electromagnetic fields. Am. Ind. Hyg. Assoc. J. 54:1993;178-185.
36. Wei L.X., Goodman R., Henderson A. Changes in level of c-myc and histone H2B following exposure of cells to low-frequency sinusoidal electromagnetic fields: evidence for a window effect. Bioelectromagnetics. 11:1990;269-272.
37. Schimmelpfeng J., Dertinger H. Action of a 50 Hz magnetic field on proliferation of cells in culture. Bioelectromagnetics. 18:1997;177-183.
38. S. Diener, P. Eberle, Zellproliferation, SCE- und Chromosomenaberrationsrate sowie Mikrokernfrequenz humaner peripherer Lymphozyten nach Einwirkung von 50-Hz-Magnetfeldern, Symposium, Elektromagnetische Verträglichkeit biologischer Systeme in schwachen 50-Hz-Magnetfeldern, 1994, pp. 17-26.
39. Bernhardt J.H. The direct influence of electromagnetic fields on nerve- and muscle cells on man within the frequency range of 1 Hz to 30 Mhz. Radiat. Environ. Biophys. 16:1979;309-323.
40. Frazier M.E., Reese J.A., Morris J.E., Jostes R.F., Miller D.L. Exposure of mammalian cells to 60-Hz magnetic or electric fields: analysis of DNA repair of induced, single-strand breaks. Bioelectromagnetics. 11:1990;229-234.
41. Cantoni O., Sestili P., Fiorani M., Dacha M. The effect of 50 Hz sinusoidal electric and/or magnetic fields on the rate of repair of DNA single/double strand breaks in oxidatively injured cells. Biochem. Mol. Biol. Int. 37:1995;681-689.