Protein kinase C activity is altered in HL60 cells exposed to 60 Hz AC electric fields

Bioelectromagnetics

Volumn 17, Issue 6, 1996, Pages 504-509

  Holian, O ^a   Astumian, R D ^b   Lee, R C ^b,c   Reyes, H M ^a   Attar, B M ^a   Walter, R J ^a  

^a MA   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Electric fields; Extremely low frequency electromagnetic fields; Phorbol 12 myristate 13 acetate; Promyelocytic leukemia cells; Protein kinase c; Signal transduction

Indexed keywords

ELECTRIC FIELDS; ELECTROMAGNETIC FIELDS; ENZYMES;

CYTOSOLS; EXPOSED TO; EXTREMELY LOW FREQUENCY ELECTROMAGNETIC FIELDS; HL-60 CELLS; LEUKAEMIA CELLS; PARTICULATE FRACTION; PHORBOL 12 MYRISTATE 13 ACETATES; PROMYELOCYTIC LEUKEMIA; PROMYELOCYTIC LEUKEMIA CELL; PROTEIN KINASES C;

SIGNAL TRANSDUCTION;

CARCINOGEN; MITOGENIC AGENT; PHORBOL 13 ACETATE 12 MYRISTATE; POLITEF; PROTEIN KINASE C;

ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CELL ORGANELLE; CELL STRAIN HL 60; CULTURE MEDIUM; CYTOPLASM; CYTOSOL; DIFFUSION CHAMBER; DOWN REGULATION; DRUG EFFECT; ELECTRICITY; ELECTROMAGNETIC FIELD; ENZYMOLOGY; HUMAN; METABOLISM;

CARCINOGENS; CELL MEMBRANE; CULTURE MEDIA; CYTOPLASM; CYTOSOL; DIFFUSION CHAMBERS, CULTURE; DOWN-REGULATION; ELECTRICITY; ELECTROMAGNETIC FIELDS; HL-60 CELLS; HUMANS; MITOGENS; ORGANELLES; POLYTETRAFLUOROETHYLENE; PROTEIN KINASE C; SUBCELLULAR FRACTIONS; TETRADECANOYLPHORBOL ACETATE;

EID: 0030337498     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-186x(1996)17:6<504::aid-bem11>3.0.co;2-k     Document Type: Article

References (35)

1. Adey WR (1990): Joint actions of environmental nonionizing electromagnetic fields and chemical pollution in cancer promotion Environ Health Perspect 86:297-305.
2. Balcer-Kubiczek EK, Harrison GH (1991): Neoplastic transformation of C3H/10T1/2 cells following exposure to 120-Hz modulated 2.45-GHz microwaves and phorbol ester tumor promoter. Radiat Res 126:65-72.
3. Byus CV, Lundak RL, Fletcher RM, Adey WR (1984): Alterations in protein kinase activity following exposure of cultured human lymphocytes to modulated microwave fields. Bioelectromagnetics 5:341-351.
4. 2+ in HL-60 cells. Am J Pathol 259:C687-C692.
5. Cho MR, Hemant ST, Lee RC, Golan DE (1994): Induced distribution of cell surface receptors by alternating current electric fields. FASEB J 8:771-776.
6. Cleary SF (1993): A review of in vitro studies: Low-frequency electromagnetic fields. Am Ind Hyg Assoc J 54:178-185.
7. Czerska E, Casamento J, Ning J (1992): Comparison of the effect of ELF on c-myc oncogene expression in normal and transformed human cells. Ann NY Acad Sci 649:340-342.
8. 2+/calmodulin-dependent protein kinase II by protein phosphatase 2C. J Biol Chem 268:133-137.
9. Goldberg RB, Creasey WA (1991): A review of cancer induction by extremely low frequency electromagnetic fields. Is there a plausible mechanism? Med Hypoth 35:265-274.
10. Goodman R, Henderson AS (1986): Sine waves enhance cellular transcription. Bioelectromagnetics 7:23-29.
11. Goodman R, Bumann J, Wei L-X, Shirley-Henderson A (1992): Exposure of human cells to electromagnetic fields: Effect of time and field strengths on transcript levels. Electr Magnetobiol 11:19-28.
12. House C, Kemp BE (1987): Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 238:1726-1728.
13. Jans DA (1994): Nuclear signaling pathways for polypeptide ligands and their membrane receptors? FASEB J 8:841-847.
14. Kikkawa U, Minakuchi R, Takai Y (1982a): Calcium activated, phospholipid-dependent protein kinase (protein kinase C) from rat brain. Methods Enzymol 99:288-298.
15. Kikkawa U, Takai Y, Minakuchi R, Inohara S, Nishizuka Y (1982b): Calcium-activated, phospholipid-dependent protein kinase from rat brain. J Biol Chem 257:13341-13348.
16. Kischel T, Harbers M, Stabel S (1989): Tumor promotion and depletion of protein kinase C in epidermal JB6 cells. Biochem Biophys Res Commun 165:981-987.
17. Liburdy RP (1992): Calcium signaling in lymphocytes and ELF fields. Evidence for an electric field metric and a site of interaction involving the calcium ion channel. FEBS Lett 13:53-59.
18. + pumping modes of (Na,K)-ATPase by an oscillating electric field. FASEB J 265:7260-7267.
19. Loscher W, Mevissen M (1994): Animal studies on the role of 50/60-hertz magnetic fields in carcinogenesis. Life Sci 54:1531-1543.
20. Lowry OH, Rosebrough NJ, Farr AL (1951): Protein measurement with the Folin-phenol reagent. J Biol Chem 193:265-275.
21. Lyle DB (1991): Calcium uptake by leukemic and normal T-lymphocytes exposed to low frequency magnetic fields. Bioelectromagnetics 12:145-156.
22. Mclean JR, Stuchly MA, Mitchel RE, Wilkinson D, Yang H, Gooddard M, Lecuyer DW, Schunk M, Callary E, Morrison D (1991): Cancer promotion in a mouse-skin model by a 60-Hz magnetic field: II. Tumor development and immune response. Bioelectromagnetics 12:273-287.
23. Misakian M, Sheppard AR, Krause D, Frazier ME, Miller DL (1993): Biological, physical, and electrical parameters for in vitro studies with ELF magnetic and electric fields: A primer. Bioelectromagnetics 2(Suppl):1-73
24. Monti MG, Pernecco L, Moruzzi MS, Battini R, Zaniol P (1991): Effect of ELF pulsed electromagnetic fields on protein kinase C activation process in HL-60 leukemia cells. J Bioelectr 10:119-130
25. Moodie SA, Willumsen BM, Wevre JJ, Wolfman A (1993): Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. Science 260:1658-1661.
26. Mortensen BT, Bojsen J (1982): Evidence for growth inhibition by platinum electrodes at low current levels. J Biomed Eng 4:103-106.
27. Newton AC (1995): Protein kinase C: Structure, function, and regulation. J Biol Chem 270:28495-28498.
28. Nishizuka Y (1988): The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-665.
29. Phillips JL, Winters W, Rutledge L (1986): In vitro exposure of electromagnetic fields: Changes in tumour cell properties. Int J Radiat Biol 49:436-469.
30. Roskoski R (1983): Assays of protein kinases. Methods Enzymol 99:3-71.
31. Sagan LA (1992): Epidemiological and laboratory studies of power frequency electric and magnetic fields. JAMA 268:625-629.
32. 2+-activated phospholipid dependent protein kinase in platelets treated with a tumor-promoting phorbol ester. Biochem Biophys Res Commun 122:158-164.
33. Uckun FM, Kurosaki T, Jin J, Jun X, Morgan A, Takata M, Bolen J, Luben RA (1995): Exposure of B-lineage lymphoid cells to low energy electromagnetic fields stimulates Lyn kinase. J Biol Chem 270:27666-27670.
34. Walleczek J (1992): Electromagnetic field effects on cells of the immune system: The role of calcium signaling. FASEB J 6:3177-3185.
35. Zar JH (1984): "Biostatistical Analysis." Englewood Cliffs, NJ: Prentice-Hall.