Effect of oral yohimbine on withdrawal jumping behaviour of morphine-dependent mice

Addiction Biology

Volumn 3, Issue 4, 1998, Pages 459-463

  Iglesias, V ^a   Alamo, C ^a   Cuenca, E ^a   Morales, L ^b   Perez Garcia, C ^b   Alguacil, L F ^b  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b UNIVERSIDAD SAN PABLO CEU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; MORPHINE; NALOXONE; TAP WATER; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ABUSE; ESCAPE BEHAVIOR; HUMAN; JUMPING; MALE; MORPHINE ADDICTION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; WITHDRAWAL SYNDROME;

EID: 0031662227     PISSN: 13556215     EISSN: None     Source Type: Journal    
DOI: 10.1080/13556219872001     Document Type: Article

References (23)

1. Charney DS, Sternberg DE, Kleber DE, Heninger GR, Redmond E. The clinical use of clonidine in abrupt withdrawal from methadone. Arch Gen Psychiatry 1981;38:1273-77.
2. Rosen MI, McMahon TJ, Hameedi A et al. Effect of clonidine pre-treatment on naloxone-precipitated opiate withdrawal. J Pharmacol Exp Ther 1996; 276:1128-35.
3. Tseng L, Log HH, Wei ET. Effects of clonidine on morphine withdrawal signs in the rat. Eur J Pharmacol 1975;30:93-9.
4. 2-adrenoceptors. Behav Pharmacol 1996;4:334-40.
5. Nakamura H, Yokoyama Y. Quantitative assessment of jumping behaviour of morphine-like analgesics in mice. Arch Int Pharmacodyn 1983;263: 164-76.
6. Alguacil LF, Alamo C, Iglesias V, Cuenca E. An automated method for the evaluation of jumping activity in mice. Effects of clonidine on morphine withdrawal. Meth Find Exp Clin Pharmacol 1989; 11:677-81.
7. Dwoskin LP, Neal BS, Sparber SB. Yohimbine exacerbates and clonidine attenuates acute morphine withdrawal in rats. Eur J Pharmacol 1983; 90:269-73.
8. Alguacil LF, Alamo C, Santos C, Cuenca E. Yohimbine reduces morphine tolerance in guinea-pig ileum. Life Sci 1987;40:155-60.
9. Iglesias V, Alguacil LF, Alamo C, Cuenca E. Effects of yohimbine on morphine analgesia and physical dependence in the rat. Eur J Pharmacol 1992; 211:35-8.
10. Taylor JR, Lewis VO, Elsworth JD, Pivirotto P, Roth RH, Redmond Jr DE. Yohimbine co-treatment during chronic morphine administration attenuates naloxone precipitated withdrawal without diminishing tail-flick analgesia in rats. Psychopharmacology 1991;103:407-14.
11. El-Kadi AOS, Sharif SI. The influence of chronic treatment with clonidine, yohimbine and idazoxan on morphine withdrawal. Psychopharmacology, 1997; 132:67-73.
12. Hameedi FA, Woods SW, Rosen MI, Pearsall HR, Kosten TR. Dose dependent effects of yohimbine on methadone maintained patients. Am J Drug Alcohol Abuse 1997;23:327-33.
13. Solomon RE, Gebhart GF. Intrethecal morphine and clonidine. Antinociceptive tolerance and cross-tolerance and effects on blood pressure. J Pharmacol Exp Ther 1988;245:444-54.
14. Smith CB, Moises HC, Spengler RN, Hollingsworth PJ. Changes in alpha-2 adrenoceptor number and function in brains of morphine-dependent rats. Eur J Pharmacol 1989;161:111-19.
15. Guthrie SK, Hariharan M, Grunhaus LJ. Yohimbine bioavailability in humans. Eur J Clin Pharmacol 1990;39:409-11.
16. Ho AKS, Hoffman DB, Gershon S, Loh HH. Distribution and metabolism of tritiated yohimbine. Arch Int Pharmacodyn 1971;194:304-15.
17. Hubbard JW, Pfister SL, Biediger AM, Herzig TC, Keeton TK. The pharmacokinetic properties of yohimbine in the conscious rat. Naunyn-Schmiedebergs Arch Pharmacol 1988;337:583-7.
18. Ambrosio E, Iglesias V, Garcia-Lecumberri C, Orensanz L, Alguacil LF. Effect of yohimbine on the development of morphine dependence in the rat: lack on involvement of cortical β-adrenoceptor modifications. Pharmacol Biochem Behav 1997;3: 487-91.
19. Cervo L, Rochat C, Romandini S, Samanin R. Evidence of a preferential role of brain serotonin in the mechanisms leading to naloxone-precipitated compulsive jumping in morphine-dependent rats. Psychopharmacology 1981;74:271-4.
20. Cheng CHK, Costall B, Ge J, Naylor RJ. The profiles of interaction of yohimbine with anxiolytic and putative anxiolytic agents to modify 5-HT release in the frontal cortex of freely-moving rats. Br J Pharmacol 1993;110:1079-84.
21. Brannan T, Martinez-Tica J, Yahr MD. Effect of yohimbine on brain monoamines: an in vivo study. J Neural Transm 1991;3:81-7.
22. Mongeau R, De Montigny C, Blier P. Effects of long-term alpha-2 adrenergic antagonists and electroconvulsive treatments on the alpha-2 adrenoceptors modulating serotonin transmission. J Pharmacol Exp Ther 1994;269:1152.
23. Winter JC, Rabin RA. Yohimbine as a serotonergic agent: evidence from receptor binding and drug discrimination. J Pharmacol Exp Ther 1992;263: 682-9.