Modification of naloxone-precipitated withdrawal symptoms in mice by drugs acting on α2-adrenoceptors

Behavioural Pharmacology

Volumn 7, Issue 4, 1996, Pages 334-340

  Sharif, S I ^a   El Kadi, A O S ^a,b  

^a AL ARAB MEDICAL UNIVERSITY   (Libyan Arab Jamahiriya)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Clonidine; Dependence; Idazoxan; Imidazoline; Morphine; Mouse; Naloxone; Withdrawal; Yohimbine

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; IDAZOXAN; IMIDAZOLINE RECEPTOR; MORPHINE; NALOXONE; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG POTENTIATION; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; JUMPING; MALE; MORPHINE ADDICTION; MOUSE; NONHUMAN; SUBCUTANEOUS DRUG ADMINISTRATION; WEIGHT REDUCTION; WET DOG SHAKES; WITHDRAWAL SYNDROME;

EID: 0029818157     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-199608000-00004     Document Type: Article

References (36)

1. 2-adrenoceptors in the control of spontaneous motility and morphine withdrawal symptoms. Bollettino-Societa Italiana Biologia Sperimentale, 67, 965-971.
2. Bläsig J, Herz A, Reinhold K and Zieglgaansberger S (1973) Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats. Psychopharmacology, 33, 19-38.
3. Buccafusco JJ, Marshall DC and Turner RM (1984) A comparison of the inhibitory effects of clonidine and guanfacine on the behavioral and autonomie components of morphine withdrawal in rats. Life Sciences, 35, 1401-1408.
4. 2-mediated analgesia and other non-cardiovascular therapeutic uses. Life Sciences, 56, 63-64.
5. 2-adrenoceptor agonists on the expression of morphine-withdrawal in rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 345, 553-557.
6. Devenyi LP, Mitwallio A and Graham W (1982) Clonidine therapy for narcotic withdrawal. Canadian Medical Association Journal, 127, 1009-1011.
7. Dwoskin LP, Neal BS and Sparber SB (1983) Yohimbine exacerbates and clonidine attenuates acute morphine withdrawal in rats. European Journal of Pharmacology, 90, 269-276.
8. El-Kadi AOS and Sharif SI (1994) The influence of various experimental conditions on the naloxone-induced withdrawal symptoms in mice. General Pharmacology, 25, 1505-1510.
9. El-Kadi AOS and Sharif SI (1995a) Investigation into the action of various adrenergic drugs in the expression of morphine withdrawal symptoms. Pharmaceutical and Pharmacological Letters, 3, 112-115.
10. El-Kadi AOS and Sharif SI (1995b) Modification by muscimol of naloxone-precipitated withdrawal symptoms in morphine-dependent mice. General Pharmacology, 26, 1579-1581.
11. El-Kadi AOS and Sharif SI (1995c) The role of 5-HT in the expression of morphine withdrawal in mice. Life Sciences, 57, 511-516.
12. El-Kadi AOS and Sharif SI (1996) The role of histaminergic-noradrenergic axis in naloxone induced withdrawal symptoms in mice. Pharmacology Biochemistry and Behavior, (in press).
13. Ernsberger P, Guiliano R, Willette and Reis DJ (1990) Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla. Journal of Pharmacology and Experimental Therapeutics, 253, 408-418.
14. Escriba PV, Ozaita A, Miralles A, Reis DJ and Garciasevilla JA (1995) Molecular characterization and isolation of a 45-kilodalton imidazoline receptor protein from the rat brain. Molecular Brain Research, 32, 187-196.
15. Fielding S, Wilkes J, Hynes M, Szewczak M, Novik WJ and Harbans L (1978) A comparison of clonidine with morphine for antinociceptive and antiwithdrawal actions. Journal of Pharmacology and Experimental Therapeutics, 207, 899-905.
16. Gold MS, Redmond DE Jr and Kleber HD (1978) Clonidine in opiate withdrawal. Lancet, 1, 929-930.
17. 2-adrenoceptors and non-adrenoceptor, imidazoline binding sites in the central nervous system. British Journal of Pharmacology, 109, 831-837.
18. Marshall I and Weinstock M (1971) A quantitative method for the assessment of physical dependence on narcotic analgesics in mice. British Journal of Pharmacology, 37, 505-506.
19. Michel MC and Ernsberger P (1992) Keeping an eye on the 1 site: imidazoline-preferring receptors. Trends in Pharmacological Sciences, 13, 369-370.
20. Michel MC and Insel P. (1989) Are there multiple imidazoline binding sites? Trends in Pharmacological Sciences, 10, 342-344.
21. 2-adrenoceptors modulating diarrhoea in morphine-dependent rats. Journal of Pharmacy and Pharmacology, 33, 397-399.
22. Schoeffter P and Hoyer D (1989) 5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity: pharmacological comparison with special reference to the effect of yohimbine, rauwolscine and some beta-adrenoceptor antagonists. Naunyn-Schmiedeberg's Archives of Pharmacology, 297, 227-231.
23. Smyth DD, Li P, Blandford DE and Penner SB (1992) Opposite rank order of potency for alpha 2-adrenoceptor agonist on water and solute excretion in the rat: two sites and/or receptors? Journal of Pharmacology and Experimental Therapeutics, 261, 1080-1086.
24. Sparber SG and Meyer DR (1978) Clonidine antagonizes naloxone-induced suppression of conditioned behaviour and body weight loss in morphine-dependent rats. Pharmacology Biochemistry and Behavior, 9, 319-325.
25. Spyraki C and Fibiger HC (1982) Clonidine-induced sedation in rats: evidence for mediation by postsynaptic alpha 2-adrenoceptors. Journal of Neural Transmission, 54, 153-163.
26. Thollander M, Hellstrom PM and Svensson TH (1989) Suppression of small intestinal motility and morphine withdrawal diarrhoea by clonidine: peripheral site of action. Acta Physiologica Scandinavica, 137, 385-392.
27. Tseng LF, Loh HH and Wei ET (1975) Effects of clonidine on morphine withdrawal signs in the rat. European Journal of Pharmacology, 30, 93-99.
28. Valeri P, Martinelli B, Pimpinella G and Severini CC (1989) Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice. Drug and Alcohol Dependence, 23, 73-77.
29. 2-receptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 329, 293-298.
30. Van der Laan JW and Jansen Van't Land C (1992) Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats. Psychopharmacology, 234, 283-288.
31. Vetulani J and Bednarczyk B (1977) Depression by clonidine of shaking behaviour elicited by nalorphine in morphine-dependent rats. Journal of Pharmacy and Pharmacology, 29, 567-569.
32. Washton AM and Resnick RB (1982) Out patient opiate detoxification. Journal of Clinical Psychiatry, 43, 39-41.
33. Wikberg JES (1989) High affinity binding of idazoxan to a non-catecholaminergic binding site in the central nervous system: description of a putative idazoxan-receptor. Pharmacology and Toxicology, 64, 152-155.
34. 2-antagonists [3H] idazoxan in the rabbit urethral smooth muscle. Biochemical Pharmacology, 41, 701-707.
35. Zebrowska-Lupina I, Przefaliniski E, Slonien M and Kleinrok Z (1977) Clonidine induced locomotor hyperactivity in rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 297, 227-231.
36. 2-adrenoceptors. European Journal of Pharmacology, 190, 203-215.