메뉴 건너뛰기




Volumn 3, Issue 4, 1998, Pages 405-412

Ethanol metabolism by macrophages: Possible role in organ damage

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ACETIC ACID; ALBUMIN; ALCOHOL; CYTOCHROME P450; OXYGEN RADICAL; SUPEROXIDE;

EID: 0031660574     PISSN: 13556215     EISSN: None     Source Type: Journal    
DOI: 10.1080/13556219871949     Document Type: Review
Times cited : (4)

References (48)
  • 2
    • 0020694402 scopus 로고
    • Investigations into the production of acetate from ethanol by human blood and bone marrow cells in vitro
    • Bond AN, Wickramasinghe SN. Investigations into the production of acetate from ethanol by human blood and bone marrow cells in vitro. Acta Haem 1983;69:303-13.
    • (1983) Acta Haem , vol.69 , pp. 303-313
    • Bond, A.N.1    Wickramasinghe, S.N.2
  • 3
    • 0022362746 scopus 로고
    • Rates of metabolism of ethanol to acetate by human neutrophil precursors and macrophages
    • Wickramasinghe SN. Rates of metabolism of ethanol to acetate by human neutrophil precursors and macrophages. Alcohol Alcohol 1985;20:299-303.
    • (1985) Alcohol Alcohol , vol.20 , pp. 299-303
    • Wickramasinghe, S.N.1
  • 4
    • 0022621291 scopus 로고
    • Observations on the biochemical basis of ethanol metabolism by human macrophages
    • Wickramasinghe SN. Observations on the biochemical basis of ethanol metabolism by human macrophages. Alcohol Alcohol 1986;21:57-63.
    • (1986) Alcohol Alcohol , vol.21 , pp. 57-63
    • Wickramasinghe, S.N.1
  • 5
    • 0023897748 scopus 로고
    • Oxidation of ethanol by human macrophages derived from the bone marrow and spleen
    • Wickramasinghe SN. Oxidation of ethanol by human macrophages derived from the bone marrow and spleen. Hematol Rev Commun 1988;2: 179-82.
    • (1988) Hematol Rev Commun , vol.2 , pp. 179-182
    • Wickramasinghe, S.N.1
  • 6
    • 0023070557 scopus 로고
    • The capacity of macrophages from different murine tissues to metabolise ethanol and generate an ethanol-dependent non-dialysable cytotoxic activity in vitro
    • Wickramasinghe SN, Barden G, Levy L. The capacity of macrophages from different murine tissues to metabolise ethanol and generate an ethanol-dependent non-dialysable cytotoxic activity in vitro. Alcohol Alcohol 1987;22:31-9.
    • (1987) Alcohol Alcohol , vol.22 , pp. 31-39
    • Wickramasinghe, S.N.1    Barden, G.2    Levy, L.3
  • 7
    • 0023511430 scopus 로고
    • Neuroglial and neuroblastoma cell lines are capable of metabolizing ethanol via an alcohol-dehydrogenase-independent pathway
    • Wickramasinghe SN. Neuroglial and neuroblastoma cell lines are capable of metabolizing ethanol via an alcohol-dehydrogenase-independent pathway. Alcohol Clin Exp Res 1987;11:234-7.
    • (1987) Alcohol Clin Exp Res , vol.11 , pp. 234-237
    • Wickramasinghe, S.N.1
  • 8
    • 0025825751 scopus 로고
    • Comparison of the generation of albumin-associated cytotoxic activity in supernatants from ethanol-containing cultures of human blood-monocyte-derived macrophages and of two human hepatoma cell lines
    • Wickramasinghe SN, Hasan R. Comparison of the generation of albumin-associated cytotoxic activity in supernatants from ethanol-containing cultures of human blood-monocyte-derived macrophages and of two human hepatoma cell lines. Alcohol Alcohol 1991;26:147-53.
    • (1991) Alcohol Alcohol , vol.26 , pp. 147-153
    • Wickramasinghe, S.N.1    Hasan, R.2
  • 9
    • 0023220694 scopus 로고
    • Role of macrophages in the pathogenesis of alcohol-induced tissue damage
    • Wickramasinghe SN. Role of macrophages in the pathogenesis of alcohol-induced tissue damage. Br Med J 1987;294:1137-9.
    • (1987) Br Med J , vol.294 , pp. 1137-1139
    • Wickramasinghe, S.N.1
  • 10
    • 0028350768 scopus 로고
    • Alcohol and the liver: 1994 update
    • Lieber CS. Alcohol and the liver: 1994 update. Gastroenterology 1994;106:1085-1105.
    • (1994) Gastroenterology , vol.106 , pp. 1085-1105
    • Lieber, C.S.1
  • 11
    • 0030592763 scopus 로고    scopus 로고
    • Alcohol dehydrogenase in human tissues: Localisation of transcripts coding for five classes of the enzyme
    • Estonius M, Svensson S, Hoog J-O. Alcohol dehydrogenase in human tissues: localisation of transcripts coding for five classes of the enzyme. FEBS Lett 1996;397:338-42.
    • (1996) FEBS Lett , vol.397 , pp. 338-342
    • Estonius, M.1    Svensson, S.2    Hoog, J.-O.3
  • 12
    • 0029829513 scopus 로고    scopus 로고
    • Ethanol-inducible cytochrome P450 (CYP2E1): Biochemistry, molecular biology and clinical relevance: 1996 update
    • Koop DR, Cederbaum AI, Song BJ, Ingelman-Sundberg M, Nanji A. Ethanol-inducible cytochrome P450 (CYP2E1): biochemistry, molecular biology and clinical relevance: 1996 update. Alcohol Clin Exp Res 1996;20:138A-46A.
    • (1996) Alcohol Clin Exp Res , vol.20
    • Koop, D.R.1    Cederbaum, A.I.2    Song, B.J.3    Ingelman-Sundberg, M.4    Nanji, A.5
  • 13
    • 0023069636 scopus 로고
    • Subcellular localization of acetaldehyde oxidation on liver
    • Weiner H. Subcellular localization of acetaldehyde oxidation on liver. Ann NY Acad Sci 1987;492: 25-34.
    • (1987) Ann NY Acad Sci , vol.492 , pp. 25-34
    • Weiner, H.1
  • 15
    • 0024507826 scopus 로고
    • Role of superoxide anion radicals in ethanol metabolism by blood monocyte-derived human macrophages
    • Wickramasinghe SN. Role of superoxide anion radicals in ethanol metabolism by blood monocyte-derived human macrophages. J Exp Med 1989;169: 755-63.
    • (1989) J Exp Med , vol.169 , pp. 755-763
    • Wickramasinghe, S.N.1
  • 16
    • 0026651273 scopus 로고
    • Human cytochromes P450: Problems and prospects
    • Gonzalez FJ. Human cytochromes P450: problems and prospects. Trends Pharmacol Sci 1992;13: 346-52.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 346-352
    • Gonzalez, F.J.1
  • 17
    • 0026005872 scopus 로고
    • Identification and induction of cytochrome P450 2E1 in rat Kupffer cells
    • Koop DR. Identification and induction of cytochrome P450 2E1 in rat Kupffer cells. J Pharmacol Exp Ther 1991;258:1072-6.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 1072-1076
    • Koop, D.R.1
  • 18
    • 0024331651 scopus 로고
    • Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow
    • Schnier GG, Laethem CL, Koop DR. Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow. J Pharmacol Exp Ther 1989;251:790-6.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 790-796
    • Schnier, G.G.1    Laethem, C.L.2    Koop, D.R.3
  • 19
    • 0025277085 scopus 로고
    • Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: Detection by the polymerase chain reaction
    • Omiecinski CJ, Redlich CA, Costa P. Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction. Cancer Res 1990; 50:4315-21.
    • (1990) Cancer Res , vol.50 , pp. 4315-4321
    • Omiecinski, C.J.1    Redlich, C.A.2    Costa, P.3
  • 20
    • 0023019235 scopus 로고
    • Cytotoxic protein molecules generated as a consequence of ethanol metabolism in vitro and in vivo
    • Wickramasinghe SN, Gardner B, Barden G. Cytotoxic protein molecules generated as a consequence of ethanol metabolism in vitro and in vivo. Lancet 1986;ii:823-6.
    • (1986) Lancet , vol.2 , pp. 823-826
    • Wickramasinghe, S.N.1    Gardner, B.2    Barden, G.3
  • 21
    • 0023257361 scopus 로고
    • Circulating cytotoxic protein generated after ethanol consumption: Identification and mechanism of reaction with cells
    • Wickramasinghe SN, Gardner B, Barden G. Circulating cytotoxic protein generated after ethanol consumption: identification and mechanism of reaction with cells. Lancet 1987;ii:122-6.
    • (1987) Lancet , vol.2 , pp. 122-126
    • Wickramasinghe, S.N.1    Gardner, B.2    Barden, G.3
  • 22
    • 0024850463 scopus 로고
    • Differences in the nature and kinetics of the ethanol-related circulating cytotoxic proteins in normal subjects and patients with alcohol-induced cirrhosis
    • Wickramasinghe SN, Clague JR, Barrison IG, Walker JG, Barden G, Gardner B. Differences in the nature and kinetics of the ethanol-related circulating cytotoxic proteins in normal subjects and patients with alcohol-induced cirrhosis. Alcohol Clin Exp Res 1989;13:723-9.
    • (1989) Alcohol Clin Exp Res , vol.13 , pp. 723-729
    • Wickramasinghe, S.N.1    Clague, J.R.2    Barrison, I.G.3    Walker, J.G.4    Barden, G.5    Gardner, B.6
  • 23
    • 0028587558 scopus 로고
    • Macrophages are a major source of acetaldehyde in circulating acetaldehyde-albumin complexes formed after exposure of mice to ethanol
    • Wickramasinghe SN, Mawas F, Hasan R, Brown IN, Goldin R. Macrophages are a major source of acetaldehyde in circulating acetaldehyde-albumin complexes formed after exposure of mice to ethanol. Alcohol Clin Exp Res 1994;18:1463-7.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 1463-1467
    • Wickramasinghe, S.N.1    Mawas, F.2    Hasan, R.3    Brown, I.N.4    Goldin, R.5
  • 24
    • 0024450665 scopus 로고
    • Acetaldehyde-modified serum proteins inhibit mitogen-stimulated human lymphocyte transformation
    • Wickramasinghe SN, Barden G. Acetaldehyde-modified serum proteins inhibit mitogen-stimulated human lymphocyte transformation. Br J Haematol 1989;73:23-8.
    • (1989) Br J Haematol , vol.73 , pp. 23-28
    • Wickramasinghe, S.N.1    Barden, G.2
  • 27
    • 0023064033 scopus 로고
    • Red blood cells: A new major modality for acetaldehyde transport from liver to other tissues
    • Baraona E, DiPadova C, Tabasco J, Leiber CS. Red blood cells: a new major modality for acetaldehyde transport from liver to other tissues. Life Sci 1987; 40:253-8.
    • (1987) Life Sci , vol.40 , pp. 253-258
    • Baraona, E.1    DiPadova, C.2    Tabasco, J.3    Leiber, C.S.4
  • 28
    • 0028183168 scopus 로고
    • 14C-acetaldehyde with whole blood in vitro: Further evidence for the formation of unstable complexes with plasma proteins and red cells
    • 14C-acetaldehyde with whole blood in vitro: further evidence for the formation of unstable complexes with plasma proteins and red cells. Alcohol Alcohol 1994;29:51-7.
    • (1994) Alcohol Alcohol , vol.29 , pp. 51-57
    • Wickramasinghe, S.N.1    Thomas, S.2    Hasan, R.3
  • 29
    • 0024596025 scopus 로고
    • Correlations between serum proteins modified by acetaldehyde and biochemical variables in heavy drinkers
    • Wickramasinghe SN, Marjot DH, Rosalki SB, Fink RS. Correlations between serum proteins modified by acetaldehyde and biochemical variables in heavy drinkers. J Clin Pathol 1989;42:295-9.
    • (1989) J Clin Pathol , vol.42 , pp. 295-299
    • Wickramasinghe, S.N.1    Marjot, D.H.2    Rosalki, S.B.3    Fink, R.S.4
  • 30
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • Adachi Y, Bradford BU, Gao W, Bojes HK, Thurman RG. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 1994;20: 453-60.
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.U.2    Gao, W.3    Bojes, H.K.4    Thurman, R.G.5
  • 32
    • 0027447937 scopus 로고
    • Ethanol alters the metabolic response of isolated, perfused rat liver to a phagocytic stimulus
    • D'Souza NB, Bagby GJ, Lang CH, Deaciuc IV, Spitzer JJ. Ethanol alters the metabolic response of isolated, perfused rat liver to a phagocytic stimulus. Alcohol Clin Exp Res 1993;17:147-54.
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 147-154
    • D'Souza, N.B.1    Bagby, G.J.2    Lang, C.H.3    Deaciuc, I.V.4    Spitzer, J.J.5
  • 34
    • 0000577327 scopus 로고
    • Metabolic alteration produced in the liver by chronic alcohol administration. Increased oxidative capacity
    • Videla L, Bernstein J, Israel Y. Metabolic alteration produced in the liver by chronic alcohol administration. Increased oxidative capacity. Biochem J 1973; 134:507-14.
    • (1973) Biochem J , vol.134 , pp. 507-514
    • Videla, L.1    Bernstein, J.2    Israel, Y.3
  • 35
    • 0008954754 scopus 로고
    • Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell
    • Bernstein J, Videla L, Israel Y. Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell. Biochem J 1973;134:515-21.
    • (1973) Biochem J , vol.134 , pp. 515-521
    • Bernstein, J.1    Videla, L.2    Israel, Y.3
  • 36
    • 2442712442 scopus 로고
    • Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver. Evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia
    • Ji S, Lemasters JJ, Christenson VR, Thurman RG. Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver. Evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia. Proc Nat Acad Sci USA 1982;79:5415-19.
    • (1982) Proc Nat Acad Sci USA , vol.79 , pp. 5415-5419
    • Ji, S.1    Lemasters, J.J.2    Christenson, V.R.3    Thurman, R.G.4
  • 37
    • 0027156592 scopus 로고
    • Kupffer cells are required for the swift increase in alcohol metabolism
    • Bradford BU, Misra UK, Thurman RG. Kupffer cells are required for the swift increase in alcohol metabolism. Res Commun Substance Abuse 1993; 14:1-6.
    • (1993) Res Commun Substance Abuse , vol.14 , pp. 1-6
    • Bradford, B.U.1    Misra, U.K.2    Thurman, R.G.3
  • 39
    • 0029036155 scopus 로고
    • Free radical adducts in the bile salts of rats treated chronically with intragastric alcohol: Inhibition by destruction of Kupffer cells
    • Knecht KT, Adachi Y, Bradford BU et al. Free radical adducts in the bile salts of rats treated chronically with intragastric alcohol: inhibition by destruction of Kupffer cells. Mol Pharmacol 1995; 47:1028-34.
    • (1995) Mol Pharmacol , vol.47 , pp. 1028-1034
    • Knecht, K.T.1    Adachi, Y.2    Bradford, B.U.3
  • 41
    • 7344233851 scopus 로고
    • Alcohol-induced liver disease
    • Billiar TR, Curran RD, editors. CRC Press, Inc.
    • Wickramasinghe SN. Alcohol-induced liver disease. In: Billiar TR, Curran RD, editors. Hepatocyte and Kupffer cell interactions. CRC Press, Inc.; 1992, p. 97-117.
    • (1992) Hepatocyte and Kupffer Cell Interactions , pp. 97-117
    • Wickramasinghe, S.N.1
  • 42
    • 0025752432 scopus 로고
    • Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism
    • Casini A, Cunningham M, Rojkind M, Lieber CS. Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 1991;13:758-65.
    • (1991) Hepatology , vol.13 , pp. 758-765
    • Casini, A.1    Cunningham, M.2    Rojkind, M.3    Lieber, C.S.4
  • 43
    • 0028125857 scopus 로고
    • Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: Localization and association with progression of liver fibrosis
    • Holstege A, Bedossa P, Poynard T, et al. Acetaldehyde-modified epitopes in liver biopsy specimens of alcoholic and nonalcoholic patients: localization and association with progression of liver fibrosis. Hepatology 1994;19:367-74.
    • (1994) Hepatology , vol.19 , pp. 367-374
    • Holstege, A.1    Bedossa, P.2    Poynard, T.3
  • 44
    • 0028239023 scopus 로고
    • Collagen-acetaldehyde adducts in alcoholic and nonalcoholic liver diseases
    • Svegliati-Baroni G, Baraona E, Rosman AS, Lieber CS. Collagen-acetaldehyde adducts in alcoholic and nonalcoholic liver diseases. Hepatology 1994; 20:111-18.
    • (1994) Hepatology , vol.20 , pp. 111-118
    • Svegliati-Baroni, G.1    Baraona, E.2    Rosman, A.S.3    Lieber, C.S.4
  • 45
    • 0029059281 scopus 로고
    • Hepatic fibrosis produced in guinea pigs by chronic ethanol administration and immunization with acetaldehyde adducts
    • Yokoyama H, Nagata S, Moriya S, Kato S, Ito T, Kamegaya K, Ishii H. Hepatic fibrosis produced in guinea pigs by chronic ethanol administration and immunization with acetaldehyde adducts. Hepatology 1995;21:1438-42.
    • (1995) Hepatology , vol.21 , pp. 1438-1442
    • Yokoyama, H.1    Nagata, S.2    Moriya, S.3    Kato, S.4    Ito, T.5    Kamegaya, K.6    Ishii, H.7
  • 46
    • 0029933084 scopus 로고    scopus 로고
    • Cytochrome P4502E1 hydroxyethyl radical adducts as the major antigen in autoantibody formation among alcoholics
    • Clot P, Albano E, Eliasson E, et al. Cytochrome P4502E1 hydroxyethyl radical adducts as the major antigen in autoantibody formation among alcoholics. Gastrocnterology 1996;111:206-16.
    • (1996) Gastrocnterology , vol.111 , pp. 206-216
    • Clot, P.1    Albano, E.2    Eliasson, E.3
  • 47
    • 0030045690 scopus 로고    scopus 로고
    • Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol
    • Albano E, Clot P, Morimoto M, Tomasi A, Ingelman-Sundberg M, French SW. Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol. Hepatology 1996;23:155-63.
    • (1996) Hepatology , vol.23 , pp. 155-163
    • Albano, E.1    Clot, P.2    Morimoto, M.3    Tomasi, A.4    Ingelman-Sundberg, M.5    French, S.W.6
  • 48
    • 0027468639 scopus 로고
    • Possible role of macrophages in the pathogenesis of ethanol-induced bone marrow damage
    • Wickramasinghe SN, Hasan R. Possible role of macrophages in the pathogenesis of ethanol-induced bone marrow damage. Br J Haematol 1993;83:574-9.
    • (1993) Br J Haematol , vol.83 , pp. 574-579
    • Wickramasinghe, S.N.1    Hasan, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.