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Volumn 88, Issue 2, 1998, Pages 192-198

Possible availability of N-acetylcysteine as an adjunct to cytokine therapy for hepatocellular carcinoma

Author keywords

Cytotoxic activity; Glutathione; Hepatocellular carcinoma; Liver associated mononuclear cells

Indexed keywords

ACETYLCYSTEINE; CYTOKINE;

EID: 0031660054     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1998.4574     Document Type: Article
Times cited : (6)

References (43)
  • 1
    • 0030039155 scopus 로고    scopus 로고
    • Analytical study of the clinical response to two distinct adoptive immunotherapies for advanced hepatocellular carcinoma: Comparison between LAK cell and CTL therapy
    • Harata, I., Yamauchi, K., Aruga, A., Komatsu, T., Takasaki, K., Hayashi, N., and Hanyu, F., Analytical study of the clinical response to two distinct adoptive immunotherapies for advanced hepatocellular carcinoma: Comparison between LAK cell and CTL therapy. J. Immunother. 19, 218-223, 1996.
    • (1996) J. Immunother. , vol.19 , pp. 218-223
    • Harata, I.1    Yamauchi, K.2    Aruga, A.3    Komatsu, T.4    Takasaki, K.5    Hayashi, N.6    Hanyu, F.7
  • 2
    • 0028824433 scopus 로고
    • Optimal locoregional immunochemotherapy after tumor-mass reduction for advanced hepatocellular carcinoma
    • Yamamoto, M., and Fujii, H., Optimal locoregional immunochemotherapy after tumor-mass reduction for advanced hepatocellular carcinoma. Hepatogastroenterology 42, 567-577, 1995.
    • (1995) Hepatogastroenterology , vol.42 , pp. 567-577
    • Yamamoto, M.1    Fujii, H.2
  • 3
    • 0010596372 scopus 로고
    • Phenotypic analysis and natural killer activity of human sinusoidal mononuclear cells
    • (M. Tsuchiya, et al. Eds.), Elsevier, Amsterdam
    • Kanai, M., Inamoto, T., Kinoshita, K., and Yamaoka, Y., Phenotypic analysis and natural killer activity of human sinusoidal mononuclear cells. In "Current Topics in Mucosal Immunology 1993" (M. Tsuchiya, et al. Eds.), pp. 253-256, Elsevier, Amsterdam, 1993.
    • (1993) Current Topics in Mucosal Immunology 1993 , pp. 253-256
    • Kanai, M.1    Inamoto, T.2    Kinoshita, K.3    Yamaoka, Y.4
  • 4
    • 0027423962 scopus 로고
    • Inhibition of epidermal growth factor-stimulated hepatocytes proliferation by autologous sinusoidal mononuclear cells in rat liver
    • Kanai, M., Inamoto, T., Kanaya, S., Kinoshita, K., Fujimura, N., and Yamauchi, A., Inhibition of epidermal growth factor-stimulated hepatocytes proliferation by autologous sinusoidal mononuclear cells in rat liver. Clin. Immunol. Immunopathol. 69, 23-28, 1993.
    • (1993) Clin. Immunol. Immunopathol. , vol.69 , pp. 23-28
    • Kanai, M.1    Inamoto, T.2    Kanaya, S.3    Kinoshita, K.4    Fujimura, N.5    Yamauchi, A.6
  • 5
    • 0026480656 scopus 로고
    • Hepatic metastasis alters the immune function of murine liver nonparenchymal cells
    • Johnkoski, J. A., Tzung, S. P., Doerr, R. J., and Cohen, S. A., Hepatic metastasis alters the immune function of murine liver nonparenchymal cells. Arch. Surg. 127, 1325-1329, 1992.
    • (1992) Arch. Surg. , vol.127 , pp. 1325-1329
    • Johnkoski, J.A.1    Tzung, S.P.2    Doerr, R.J.3    Cohen, S.A.4
  • 8
    • 0027487310 scopus 로고
    • Requirement of thiol compounds as reducing agents for IL-2-mediated induction of LAK activity and proliferation of human NK cells
    • Yamauchi, A., and Bloom, E. T., Requirement of thiol compounds as reducing agents for IL-2-mediated induction of LAK activity and proliferation of human NK cells. J. Immunol. 151, 5535-5544, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 5535-5544
    • Yamauchi, A.1    Bloom, E.T.2
  • 9
    • 0026584120 scopus 로고
    • Significance of plasma glutathione determination in patients with alcoholic and non-alcoholic liver disease
    • Shigesawa, T., Sato, C., and Marumo, F., Significance of plasma glutathione determination in patients with alcoholic and non-alcoholic liver disease. J. Gastroenterol. Hepatol. 7, 7-11, 1992.
    • (1992) J. Gastroenterol. Hepatol. , vol.7 , pp. 7-11
    • Shigesawa, T.1    Sato, C.2    Marumo, F.3
  • 10
    • 0023786779 scopus 로고
    • Hepatic glutathione content in patients with alcoholic and nonalcoholic liver diseases
    • Altomare, E., Vendemiale, G., and Albano, O., Hepatic glutathione content in patients with alcoholic and nonalcoholic liver diseases. Life Sci. 43, 991-998, 1988.
    • (1988) Life Sci. , vol.43 , pp. 991-998
    • Altomare, E.1    Vendemiale, G.2    Albano, O.3
  • 11
    • 0025364074 scopus 로고
    • Liver glutathione contents in patients with gastric adenocarcinomas
    • Engin, A., and Ferahköse, Z., Liver glutathione contents in patients with gastric adenocarcinomas. Tumori 76, 48-50, 1990.
    • (1990) Tumori , vol.76 , pp. 48-50
    • Engin, A.1    Ferahköse, Z.2
  • 12
    • 0029338193 scopus 로고
    • Altered glutathione metabolism in tumor-bearing state
    • Blumberg, D., Hochwald, S., Pinto, J., and Burt, M., Altered glutathione metabolism in tumor-bearing state. Ann. Surg. Oncol. 2, 332-335, 1995.
    • (1995) Ann. Surg. Oncol. , vol.2 , pp. 332-335
    • Blumberg, D.1    Hochwald, S.2    Pinto, J.3    Burt, M.4
  • 13
    • 0020581196 scopus 로고
    • Quantification of natural cytotoxicity by human lymphocyte subpopulations isolated by density: Heterogeneity of the effector cells
    • Bloom, E. T., and Korn, E. L., Quantification of natural cytotoxicity by human lymphocyte subpopulations isolated by density: Heterogeneity of the effector cells. J. Immunol. Methods 58, 323-335, 1983.
    • (1983) J. Immunol. Methods , vol.58 , pp. 323-335
    • Bloom, E.T.1    Korn, E.L.2
  • 14
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze, F., Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Anal. Biochem. 27, 502-522, 1969.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 15
    • 0022272493 scopus 로고
    • Determination of glutathione and glutathione disulfide in biological samples
    • Anderson, M. E., Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 113, 548-555, 1985.
    • (1985) Methods Enzymol. , vol.113 , pp. 548-555
    • Anderson, M.E.1
  • 16
    • 0028211196 scopus 로고
    • Natural killer cells, lymphokine-activated killer cells, and cytolytic T lymphocytes: Compartmentalization of age-related changes in cytolytic lymphocytes?
    • Bloom, E. T., Natural killer cells, lymphokine-activated killer cells, and cytolytic T lymphocytes: Compartmentalization of age-related changes in cytolytic lymphocytes? J. Gerontol. 49, B85-B92, 1994.
    • (1994) J. Gerontol. , vol.49
    • Bloom, E.T.1
  • 18
    • 0023256944 scopus 로고
    • Natural killer and activited killer activities in chronic liver disease and hepatocellular carcinoma: Evidence for a decreased lymphokine-induced activity of effector cells
    • Hirofuji, H., Kakumu, S., Fuji, A., Ohtani, Y., Murase, K., and Tahara, H., Natural killer and activited killer activities in chronic liver disease and hepatocellular carcinoma: Evidence for a decreased lymphokine-induced activity of effector cells. Clin. Exp. Immunol. 68, 348-356, 1987.
    • (1987) Clin. Exp. Immunol. , vol.68 , pp. 348-356
    • Hirofuji, H.1    Kakumu, S.2    Fuji, A.3    Ohtani, Y.4    Murase, K.5    Tahara, H.6
  • 19
    • 0025183084 scopus 로고
    • Defective immunological fuctions associated with abnormal lymphokine-activated killer activity in patients with hepatocellular carcinoma
    • Shirai, M., Watanabe, S., and Nishioka, M., Defective immunological fuctions associated with abnormal lymphokine-activated killer activity in patients with hepatocellular carcinoma. J. Gastroenterol. Hepatol. 5, 542-548, 1990.
    • (1990) J. Gastroenterol. Hepatol. , vol.5 , pp. 542-548
    • Shirai, M.1    Watanabe, S.2    Nishioka, M.3
  • 20
    • 0025635602 scopus 로고
    • Intratumoral injection of OK432 and lymphokine-activated killer activity in peripheral blood of patients with hepatocellular carcinoma
    • Shirai, M., Watanabe, S., and Nishioka, M., Intratumoral injection of OK432 and lymphokine-activated killer activity in peripheral blood of patients with hepatocellular carcinoma. Eur. J. Cancer. 26, 965-969, 1990.
    • (1990) Eur. J. Cancer. , vol.26 , pp. 965-969
    • Shirai, M.1    Watanabe, S.2    Nishioka, M.3
  • 21
    • 0024315847 scopus 로고
    • Lymphokine-activated killer cells in patients with primary and metastatic malignant liver tumors
    • Schwarz, R., Iwatsuki, S., Herberman, R. B., and Whiteside, T. L., Lymphokine-activated killer cells in patients with primary and metastatic malignant liver tumors. Hepatology 10, 221-227, 1989.
    • (1989) Hepatology , vol.10 , pp. 221-227
    • Schwarz, R.1    Iwatsuki, S.2    Herberman, R.B.3    Whiteside, T.L.4
  • 22
    • 0023070159 scopus 로고
    • Depressed natural cytotoxicity but normal natural killer cytotoxicity factor (NKCF) production by mononuclear cells derived from patients with hepatocellular carcinoma
    • Brookes, R. H., Kew, M. C., and Rabson, A. R., Depressed natural cytotoxicity but normal natural killer cytotoxicity factor (NKCF) production by mononuclear cells derived from patients with hepatocellular carcinoma. Cancer Immunol. Immunother. 25, 149, 1987.
    • (1987) Cancer Immunol. Immunother. , vol.25 , pp. 149
    • Brookes, R.H.1    Kew, M.C.2    Rabson, A.R.3
  • 24
    • 0026075006 scopus 로고
    • Natural killer activity of liver-derived lymphocytes in various liver diseases
    • Hata, K., Van Ronald, D. H., Herberman, R. B., and Whiteside, T. L., Natural killer activity of liver-derived lymphocytes in various liver diseases. Hepatology 14, 496-503, 1991.
    • (1991) Hepatology , vol.14 , pp. 496-503
    • Hata, K.1    Van Ronald, D.H.2    Herberman, R.B.3    Whiteside, T.L.4
  • 25
    • 0025906594 scopus 로고
    • Glutathione modulates activation dependent proliferation of human peripheral blood lymphocyte populations without regulating their activated function
    • Smyth, M. J., Glutathione modulates activation dependent proliferation of human peripheral blood lymphocyte populations without regulating their activated function. J. Immunol. 146, 1921-1927, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 1921-1927
    • Smyth, M.J.1
  • 27
    • 0027395940 scopus 로고
    • Cysteine and glutathione deficiency in AIDS patients: A rationale for the treatment with N-acetyl-cysteine
    • Droge, W., Cysteine and glutathione deficiency in AIDS patients: A rationale for the treatment with N-acetyl-cysteine. Pharmacology 46, 61-65, 1993.
    • (1993) Pharmacology , vol.46 , pp. 61-65
    • Droge, W.1
  • 28
    • 0026588635 scopus 로고
    • HIV-induced cysteine deficiency and T-cell dysfunction - A rationale for treatment with N-acetylcysteine
    • Droge, W., Eck, H. P., and Mihm, S., HIV-induced cysteine deficiency and T-cell dysfunction - A rationale for treatment with N-acetylcysteine. Immunol. Today 13, 211-214, 1992.
    • (1992) Immunol. Today , vol.13 , pp. 211-214
    • Droge, W.1    Eck, H.P.2    Mihm, S.3
  • 30
    • 0028959114 scopus 로고
    • Transforming growth factor-β1 (TGF-β1) and TGF-β1 receptors in normal, cirrhotic, and neoplastic human livers
    • Bedossa, P., Peltier, E., Terris, B., Franco, D., and Poynard, T., Transforming growth factor-β1 (TGF-β1) and TGF-β1 receptors in normal, cirrhotic, and neoplastic human livers. Hepatology 21, 760, 1995.
    • (1995) Hepatology , vol.21 , pp. 760
    • Bedossa, P.1    Peltier, E.2    Terris, B.3    Franco, D.4    Poynard, T.5
  • 31
    • 0028301747 scopus 로고
    • Plasma transforming growth factor-β1 in patients with hepatocellular carcinoma. Comparison with chronic liver diseases
    • Shirai, Y., Kawata, S., Tamura, S., Ito, N., Tsushima, H., Takaishi, K., Kiso, S., and Matsuzawa, Y., Plasma transforming growth factor-β1 in patients with hepatocellular carcinoma. Comparison with chronic liver diseases. Cancer 73, 2275-2279, 1994.
    • (1994) Cancer , vol.73 , pp. 2275-2279
    • Shirai, Y.1    Kawata, S.2    Tamura, S.3    Ito, N.4    Tsushima, H.5    Takaishi, K.6    Kiso, S.7    Matsuzawa, Y.8
  • 32
  • 36
    • 0030744380 scopus 로고    scopus 로고
    • Glutathione S-transferase expression in hepatitis B virus B virus-associated human hepatocellular carcinogenesis
    • Zhou, T., Evans, A. A., Thomas London, W., Xia, X., Zou, X., Shen, Fu-min, and Clapper, M. L., Glutathione S-transferase expression in hepatitis B virus B virus-associated human hepatocellular carcinogenesis. Cancer Res. 57, 2749-2753, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2749-2753
    • Zhou, T.1    Evans, A.A.2    Thomas London, W.3    Xia, X.4    Zou, X.5    Shen, F.-M.6    Clapper, M.L.7
  • 38
    • 0029841427 scopus 로고    scopus 로고
    • Oxidative stress by tumor-derived macrophages suppresses the expression of CDζ chain of T-cell receptor complex and antigen-specific T-cell responses
    • Otsuji, M., Kimura, Y., Aoe, T., Okamoto, Y., and Saito, T., Oxidative stress by tumor-derived macrophages suppresses the expression of CDζ chain of T-cell receptor complex and antigen-specific T-cell responses. Proc. Natl. Acad. Sci. USA 93, 13119-13124, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13119-13124
    • Otsuji, M.1    Kimura, Y.2    Aoe, T.3    Okamoto, Y.4    Saito, T.5
  • 39
    • 0028352803 scopus 로고
    • Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2
    • Yim, C. Y., Hibbs, J. B., Jr., McGregor, J. R., Galinsky, R. E., and Samlowski, W. E., Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J. Immunol. 152, 5796-5805, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 5796-5805
    • Yim, C.Y.1    Hibbs J.B., Jr.2    McGregor, J.R.3    Galinsky, R.E.4    Samlowski, W.E.5
  • 40
    • 0028604430 scopus 로고
    • Thiol supplier N-acetylcysteine enhances conjugate formation between natural killer cells and K562 or U937 targets but increases the lytic function only against the latter
    • Malorni, W., D' Ambrosio, A., Rainaldi, G., Rivabene, R., and Viora, M., Thiol supplier N-acetylcysteine enhances conjugate formation between natural killer cells and K562 or U937 targets but increases the lytic function only against the latter. Immunol. Lett. 43, 209-214, 1994.
    • (1994) Immunol. Lett. , vol.43 , pp. 209-214
    • Malorni, W.1    D' Ambrosio, A.2    Rainaldi, G.3    Rivabene, R.4    Viora, M.5
  • 41
    • 0031026805 scopus 로고    scopus 로고
    • N-Acetylcysteine improves indocyanine green extraction and oxygen transport during hepatic dysfuction
    • Devlin, J., Ellis, A. E., McPeake, J., Heaton, N., Wendon, J. A., Williams, R., N-Acetylcysteine improves indocyanine green extraction and oxygen transport during hepatic dysfuction. Crit. Care Med. 25, 236-242, 1997.
    • (1997) Crit. Care Med. , vol.25 , pp. 236-242
    • Devlin, J.1    Ellis, A.E.2    McPeake, J.3    Heaton, N.4    Wendon, J.A.5    Williams, R.6
  • 42
    • 0030929953 scopus 로고    scopus 로고
    • Pharmacokinetics of N-acetylcysteine are altered in patients with chronic liver disease
    • Jones, A. L., Javie, D. R., Simpson, D., Hayes, P. C., and Prescott, L. F., Pharmacokinetics of N-acetylcysteine are altered in patients with chronic liver disease. Aliment. Pharmacol. Ther. 11, 787-791, 1997.
    • (1997) Aliment. Pharmacol. Ther. , vol.11 , pp. 787-791
    • Jones, A.L.1    Javie, D.R.2    Simpson, D.3    Hayes, P.C.4    Prescott, L.F.5
  • 43
    • 0026441505 scopus 로고
    • Glutathione treatment of hepatocellular carcinoma
    • Dalhoff, K., Ranek, L., Mantoni, M., and Poulson, H. E., Glutathione treatment of hepatocellular carcinoma. Liver 12, 341-345, 1992.
    • (1992) Liver , vol.12 , pp. 341-345
    • Dalhoff, K.1    Ranek, L.2    Mantoni, M.3    Poulson, H.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.