Relationship between immune state and tumor growth rate in rats bearing progressive and non-progressive mammary tumors

Cancer Immunology Immunotherapy

Volumn 46, Issue 6, 1998, Pages 350-354

  Remedi, María Mónica ^a   Hliba, Ernesto ^a   Demarchi, Marcela ^a   Depiante Depaoli, Mirtha ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

DTH reaction; Nitric oxide; Oxygen radicals; Progressive and non progressive tumor; Rats

Indexed keywords

CANCER VACCINE; NITRIC OXIDE; OXYGEN RADICAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CELLULAR IMMUNITY; CORRELATION FUNCTION; EXPERIMENTAL NEOPLASM; FEMALE; HELPER CELL; HISTOPATHOLOGY; IMMUNE RESPONSE; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE SUBPOPULATION; TUMOR GROWTH;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADENOCARCINOMA; ANIMALS; CARCINOMA, DUCTAL, BREAST; DISEASE PROGRESSION; ERYTHROCYTES; FEMALE; HEMAGGLUTINATION TESTS; HYPERSENSITIVITY, DELAYED; IMMUNITY, CELLULAR; IMMUNIZATION; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MAMMARY NEOPLASMS, EXPERIMENTAL; NITRIC OXIDE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SHEEP;

EID: 0031658931     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050497     Document Type: Article

References (21)

1. Adams DO, Hamilton TA (1984) The cell biology of macrophage activation. Annu Rev Immunol 2:283
2. Albina JE, Abate JA, Henry WL Jr (1991) Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. J Immunol 147:144
3. Aoe T, Okamoto Y, Saito T (1995) Activated macrophages induced structural abnormalities of the T cell receptor-CD3 complex. J Exp Med 181:1881
4. Basso AM, Depiante-Depaoli M, Cancela L, Molina VA (1994) Chronic restraint attenuates the immunosuppressive response induced by novel aversive stimuli. Physiol Behav 55:1151
5. Benson JL, Niederkorn JY (1992) Immune privilege in the anterior chamber of the eye: alloantigens and tumour-specific antigens presented into the anterior chamber simultaneously induce suppression and activation of delayed hypersensitivity to the respective antigens. Immunology 77:189
6. Fiander AN, Adams M, Evans AS, Bennett AJ, Borysiewicz LK (1995) Immunocompetent for immunotherapy? A study of the immunocompetence of cervical cancer patients. Int J Gynecol Cancer 5:438
7. Finke JH, Zea AH, Stanley J, Longo DL, Mizoguchi H, Tubbs RR, Wiltrout RH, O'Shea JJ, Kudoh S, Klein E, Bukowski RM, Ochoa AC (1993) Loss of T-cell receptor zeta chain and p561ck in T-cells infiltrating human renal cell carcinoma. Cancer Res 53:5613
8. Gorelik L, Prokhorova A, Mokyr MB (1994) Low-dose melphalan-induced shift in the production of a Th2-type cytokine to a Th1-type cytokine in mice bearing a large MOPC-315 tumor. Cancer Immunol Immunother 39:117
9. Kobayashi Y, Yoshikawa T, Watanabe N (1992) Tumor cytostasis mediated by LPS-or PSK-activated human plastic adherent peripheral blood mononuclear cells. Cell Immunol 144:358
10. Maeda H, Shiraishi A (1996) TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice. J Immunol 156:73
11. Matsuda M, Petersson M, Lenlei R, Taupin JL, Magnusson I, Mellstedt H, Anderson P, Kiessling R (1995) Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease. Int J Cancer 61:765
12. Mizoguchi H, O'Shea JJ, Longo DL, Loeffler CM, McVicar DW, Ochoa AC (1992) Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science 258:1795
13. Mossmann TR, Moore KW (1991) The role of IL-10 in cross-regulation of Th1 and Th2 responses. Immunol Today 12:A49
14. Nakagomi H, Petersson M, Magnusson I, Jublin C, Matsuda M, Mellstedt H, Taupin JL, Vivier, Anderson P, Kiessling R (1993) Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res 53:5610
15. + effector T cells. J Exp Med 159:1295
16. Pacheco-Rupil B, Depiante-Depaoli M, Hliba E (1987) Induction of mammary tumors in Wistar rats by intragastric intubation and by intramammary injection of 9-10 dimethyl-1-2 benzanthrancene. Cell Mol Biol 33:469
17. + T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. Cancer Immunol Immunother 42:1
18. Stuehr DJ, Nathan CF (1989) Nitric Oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp Med 169:1543
19. Umansky V, Rocha M, Krüger A, VonHoegen P, Schirrmacher V (1995) In situ activated macrophages are involved in host resistance to lymphoma metastasis by production of nitric oxide. Int J Oncol 7:33
20. Webb S, Morris C, Sprent J (1990) Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell 63:1249
21. Zembala M, Lemmel EM, Uracz W (1980) Activation of human monocytes for nitroblue tetrazolium reduction and the suppression of lymphocyte response to mitogens. Clin Exp Immunol 41:309