Convulsions due to increased permeability of the blood-brain barrier in experimental cerebral malaria can be prevented by splenectomy or anti-T cell treatment

Journal of Infectious Diseases

Volumn 178, Issue 4, 1998, Pages 1225-1227

  Hermsen, C C ^a   Mommers, E ^a   Van De Wiel, T ^a   Sauerwein, R W ^a   Eling, W M C ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID; OKT 4; OKT 8;

ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BODY TEMPERATURE; BRAIN MALARIA; CONVULSION; FEMALE; HELPER CELL; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM BERGHEI; PRIORITY JOURNAL; SPLENECTOMY; T LYMPHOCYTE SUBPOPULATION; TREATMENT OUTCOME;

EID: 0031658253     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515691     Document Type: Article

References (15)

1. Curfs JHAJ, Schetters TPM, Hermsen CC, Jerusalem CR, van Zon AAJC, Eling WMC. Immunological aspects of cerebral lesions in murine malaria. Clin Exp Immunol 1989;75:136-40.
2. Grau GE, Fajardo LF, Piquet PF, Allet B, Lambert PH, Vassalli P. Tumor necrosis factor (cachetin) as an essential mediator in murine cerebral malaria. Science 1987;237:1210-2.
3. Curfs JHAJ, Hermsen CC, Meuwissen JETH, Eling WMC. Immunization against cerebral pathology in Plasmodium berghei-infected mice. Parasitology 1992;105:7-14.
4. Polder TW, Eling WMC, Curfs JHAJ, Jerusalem CR, Wijers-Rouw M. Ultrastructural changes in the blood-brain barrier of mice infected with Plasmodium berghei. Acta Leidensia 1992;60:31-46.
5. Thumwood CM, Hunt NH, Clark IA, Cowden WB. Breakdown of the blood-brain barrier in murine cerebral malaria. Parasitology 1988;96:579-89.
6. Neill AL, Hunt NH. Pathology of fatal and resolving murine cerebral malaria. Parasitology 1992;105:165-75.
7. Neill AL, Chan-Ling T, Hunt NH. Comparisons between microvascular changes in cerebral and non-cerebral malaria in mice, using the retinal whole-mount technique. Parasitology 1993;107:477-87.
8. Molyneux ME, Taylor TE, Wirima JJ, Borgstein J. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. QJM 1989;71:441-59.
9. Waruiru CM, Newton CRJC, Forster D, et al. Epileptic seizures and malaria in Kenyan children. Trans R Soc Trop Med Hyg 1996;90:152-5.
10. World Health Organization, Division of Tropical Diseases. Severe and complicated malaria. Trans R Soc Trop Med Hyg 1990:84(suppl 2);1-65.
11. Das BS, Mohanty S, Mishra SK, et al. Increased cerebrospinal fluid protein and lipid peroxidation products in patients with cerebral malaria. Trans R Soc Trop Med Hyg 1991;85:733-4.
12. Patnaik JK, Das BS, Mishra SK, Mohanty S, Satpathy SK, Mohanty D. Vascular clogging, mononuclear cell margination, and enhanced vascular permeability in the pathogenesis of human cerebral malaria. Am J Trop Med Hyg 1994;51:642-7.
13. Hommes OR, Obbens EAMT, Wijffels CCB. Epileptogenic activity of sodium-folate and the blood-brain barrier in the rat. J Neurol Sci 1973;19:63-71.
14. + T-cells prevents Plasmodium berghei induced cerebral malaria in end-stage disease. Parasitology 1997;114:7-12.
15. Neill AL, Hunt NH. Effects of endotoxin and dexamethasone on cerebral malaria in mice. Parasitology 1995;111:443-54.