메뉴 건너뛰기




Volumn 57, Issue 9, 1998, Pages 822-830

Immunohistochemical localization of brain-derived neurotrophic factor in the spinal cords of amyotrophic lateral sclerosis and non-amyotrophic lateral sclerosis patients

Author keywords

Amyotrophic lateral sclerosis; Brain derived neurotrophic factor; Human spinal cord; Immunohistochemistry; Motor neuron

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

EID: 0031656801     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199809000-00003     Document Type: Article
Times cited : (18)

References (48)
  • 1
    • 0020338405 scopus 로고
    • Purification of a new neurotrophic factor from mammalian brain
    • Barde Y-A, Edgar D, Thoenen H. Purification of a new neurotrophic factor from mammalian brain. EMBO J 1982;1:549-53
    • (1982) EMBO J , vol.1 , pp. 549-553
    • Barde, Y.-A.1    Edgar, D.2    Thoenen, H.3
  • 2
    • 0024451643 scopus 로고
    • Molecular cloning and expression of brain-derived neurotrophic factor
    • Leibrock J, Lottspeich F, Hohn A, et al. Molecular cloning and expression of brain-derived neurotrophic factor. Nature 1989;341: 149-52
    • (1989) Nature , vol.341 , pp. 149-152
    • Leibrock, J.1    Lottspeich, F.2    Hohn, A.3
  • 4
    • 0019071287 scopus 로고
    • Physiology of nerve growth factor
    • Thoenen H, Barde Y-A. Physiology of nerve growth factor. Physiol Rev 1980;60:1284-335
    • (1980) Physiol Rev , vol.60 , pp. 1284-1335
    • Thoenen, H.1    Barde, Y.-A.2
  • 5
    • 0022519440 scopus 로고
    • Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells
    • Johnson JE, Barde Y-A, Schwab M, Thoenen H. Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci 1986;6:3031-38
    • (1986) J Neurosci , vol.6 , pp. 3031-3038
    • Johnson, J.E.1    Barde, Y.-A.2    Schwab, M.3    Thoenen, H.4
  • 6
    • 0025168085 scopus 로고
    • Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture
    • Alderson RF, Alterman AL, Barde Y-A, Lindsay RM. Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron 1990;5:297-306
    • (1990) Neuron , vol.5 , pp. 297-306
    • Alderson, R.F.1    Alterman, A.L.2    Barde, Y.-A.3    Lindsay, R.M.4
  • 7
    • 0026714437 scopus 로고
    • Neurotrophic effect of brain-derived neurotrophic factor on basal forebrain cholinergic neurons in culture from postnatal rats
    • Nonomura T, Hatanaka H. Neurotrophic effect of brain-derived neurotrophic factor on basal forebrain cholinergic neurons in culture from postnatal rats. Neurosci Res 1992;14:226-33
    • (1992) Neurosci Res , vol.14 , pp. 226-233
    • Nonomura, T.1    Hatanaka, H.2
  • 8
    • 0025876757 scopus 로고
    • BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
    • Hyman C, Hofer M, Barde Y-A, et al. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 1991;350:230-32
    • (1991) Nature , vol.350 , pp. 230-232
    • Hyman, C.1    Hofer, M.2    Barde, Y.-A.3
  • 9
    • 0028800803 scopus 로고
    • The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro
    • Ventimiglia R, Mather PE, Jones BE, Lindsay RM. The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur J Neurosci 1995;7:213-22
    • (1995) Eur J Neurosci , vol.7 , pp. 213-222
    • Ventimiglia, R.1    Mather, P.E.2    Jones, B.E.3    Lindsay, R.M.4
  • 10
    • 0027423233 scopus 로고
    • Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity
    • Lindholm D, Dechant G, Heisenberg C-P, Thoenen H. Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur J Neurosci 1993;5:1455-64
    • (1993) Eur J Neurosci , vol.5 , pp. 1455-1464
    • Lindholm, D.1    Dechant, G.2    Heisenberg, C.-P.3    Thoenen, H.4
  • 11
    • 0027318116 scopus 로고
    • Neurotrophins promote motor neuron survival and are present in embryonic limb bud
    • Henderson CE, Camu W, Mettling C, et al. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 1993;363:266-70
    • (1993) Nature , vol.363 , pp. 266-270
    • Henderson, C.E.1    Camu, W.2    Mettling, C.3
  • 12
    • 0027316366 scopus 로고
    • The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons
    • Wong V, Arriaga R, Ip NY, Lindsay RM. The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons. Eur J Neurosci 1993;5:466-74
    • (1993) Eur J Neurosci , vol.5 , pp. 466-474
    • Wong, V.1    Arriaga, R.2    Ip, N.Y.3    Lindsay, R.M.4
  • 13
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan Q, Elliott J, Snider WD. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 1992;360:753-55
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 14
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner M, Holtmann B, Kolbeck R, Thoenen H, Barde Y-A. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1992;360:757-59
    • (1992) Nature , vol.360 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.-A.5
  • 15
    • 0027481752 scopus 로고
    • Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
    • Koliatsos VE, Clatterbuck RE, Winslow JW, Cayouette MH, Price DL. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron 1993;10:359-67
    • (1993) Neuron , vol.10 , pp. 359-367
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Winslow, J.W.3    Cayouette, M.H.4    Price, D.L.5
  • 16
    • 0028314650 scopus 로고
    • Further characterization of the effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on axotomized neonatal and adult mammalian motor neurons
    • Clatterbuck RE, Price DL, Koliatsos VE. Further characterization of the effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on axotomized neonatal and adult mammalian motor neurons. J Comp Neurol 1994;342:45-56
    • (1994) J Comp Neurol , vol.342 , pp. 45-56
    • Clatterbuck, R.E.1    Price, D.L.2    Koliatsos, V.E.3
  • 17
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death
    • Oppenheim RW, Qin-Wei Y, Prevette D, Yan Q. Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 1992;360:755-57
    • (1992) Nature , vol.360 , pp. 755-757
    • Oppenheim, R.W.1    Qin-Wei, Y.2    Prevette, D.3    Yan, Q.4
  • 18
    • 0029020311 scopus 로고
    • Neurotrophins promote maturation of developing neuromuscular synapses
    • Wang T, Xie K, Lu B. Neurotrophins promote maturation of developing neuromuscular synapses. J Neurosci 1995;15:4796-805
    • (1995) J Neurosci , vol.15 , pp. 4796-4805
    • Wang, T.1    Xie, K.2    Lu, B.3
  • 19
    • 0027281189 scopus 로고
    • Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF
    • Lohof AM, Ip NY, Poo MM. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature 1993;363:350-53
    • (1993) Nature , vol.363 , pp. 350-353
    • Lohof, A.M.1    Ip, N.Y.2    Poo, M.M.3
  • 20
    • 0027360908 scopus 로고
    • Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve
    • Funakoshi H, Frisén J, Barbany G, et al. Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. J Cell Biol 1993;123:455-65
    • (1993) J Cell Biol , vol.123 , pp. 455-465
    • Funakoshi, H.1    Frisén, J.2    Barbany, G.3
  • 21
    • 0026768108 scopus 로고
    • Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA
    • Meyer M, Matsuoka I, Wetmore C, Olson L, Thoenen H. Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol 1992;119:45-54
    • (1992) J Cell Biol , vol.119 , pp. 45-54
    • Meyer, M.1    Matsuoka, I.2    Wetmore, C.3    Olson, L.4    Thoenen, H.5
  • 22
    • 0027969192 scopus 로고
    • The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor
    • Yan Q, Matheson C, Lopez OT, Miller JA. The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor. J Neurosci 1994;14:5281-91
    • (1994) J Neurosci , vol.14 , pp. 5281-5291
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3    Miller, J.A.4
  • 23
    • 0028916844 scopus 로고
    • Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease
    • Ikeda K, Klinkosz B, Greene T et al. Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease. Ann Neurol 1995;37:505-11
    • (1995) Ann Neurol , vol.37 , pp. 505-511
    • Ikeda, K.1    Klinkosz, B.2    Greene, T.3
  • 25
    • 0030271247 scopus 로고    scopus 로고
    • Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain
    • Kawamoto Y, Nakamura S, Nakano S, Oka N, Akiguchi I, Kimura J Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain. Neuroscience 1996;74:1209-26
    • (1996) Neuroscience , vol.74 , pp. 1209-1226
    • Kawamoto, Y.1    Nakamura, S.2    Nakano, S.3    Oka, N.4    Akiguchi, I.5    Kimura, J.6
  • 26
    • 0025731382 scopus 로고
    • TrkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
    • Squinto SP, Stitt TN, Aldrich TH, et al. TrkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor. Cell 1991;65:885-93
    • (1991) Cell , vol.65 , pp. 885-893
    • Squinto, S.P.1    Stitt, T.N.2    Aldrich, T.H.3
  • 27
    • 0025827738 scopus 로고
    • The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor
    • Soppet D, Escandon E, Maragos J, et al. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell 1991;65:895-903
    • (1991) Cell , vol.65 , pp. 895-903
    • Soppet, D.1    Escandon, E.2    Maragos, J.3
  • 28
    • 0025873435 scopus 로고
    • The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3
    • Klein R, Nanduri V, Jing S, et al. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 1991;66:395-403
    • (1991) Cell , vol.66 , pp. 395-403
    • Klein, R.1    Nanduri, V.2    Et, J.S.3
  • 29
    • 0027161055 scopus 로고
    • Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system
    • Zhou X-F, Parada LF, Soppet D, Rush RA. Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system. Brain Res 1993;622:63-70
    • (1993) Brain Res , vol.622 , pp. 63-70
    • Zhou, X.-F.1    Parada, L.F.2    Soppet, D.3    Rush, R.A.4
  • 31
    • 73049155988 scopus 로고
    • The isolation of nerve endings from brain: An electron-microscopic study of cell fragments derived by homogenization and centrifugation
    • Gray EG, Whittaker VP. The isolation of nerve endings from brain: An electron-microscopic study of cell fragments derived by homogenization and centrifugation. J Anat 1962;96:79-88
    • (1962) J Anat , vol.96 , pp. 79-88
    • Gray, E.G.1    Whittaker, V.P.2
  • 32
    • 0020955120 scopus 로고
    • Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
    • Huttner WB, Schiebler W, Greengard P, De Camilli P. Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 1983;96:1374-88
    • (1983) J Cell Biol , vol.96 , pp. 1374-1388
    • Huttner, W.B.1    Schiebler, W.2    Greengard, P.3    De Camilli, P.4
  • 33
    • 0028246621 scopus 로고
    • Subcellular localization of the F5 protein to the Neuronal membrane-associated cytoskeleton
    • Arai M, Cohen JA. Subcellular localization of the F5 protein to the Neuronal membrane-associated cytoskeleton. J Neurosci Res 1994;38:348-57
    • (1994) J Neurosci Res , vol.38 , pp. 348-357
    • Arai, M.1    Cohen, J.A.2
  • 34
    • 0031019362 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 in Lewy body-like inclusions in anterior horn cells of a patient with sporadic amyotrophic lateral sclerosis
    • Nakamura S, Kawamoto Y, Nakano S, Ikemoto A, Akiguchi I, Kimura J. Cyclin-dependent kinase 5 in Lewy body-like inclusions in anterior horn cells of a patient with sporadic amyotrophic lateral sclerosis. Neurology 1997;48:267-70
    • (1997) Neurology , vol.48 , pp. 267-270
    • Nakamura, S.1    Kawamoto, Y.2    Nakano, S.3    Ikemoto, A.4    Akiguchi, I.5    Kimura, J.6
  • 35
    • 0025720531 scopus 로고
    • Human and rat brain-derived neurotrophic factor and neurotrophin-3: Gene structures, distributions, and chromosomal localizations
    • Maisonpierre PC, Le Beau MM, Espinosa R III, et al. Human and rat brain-derived neurotrophic factor and neurotrophin-3: Gene structures, distributions, and chromosomal localizations. Genomics 1991;10:558-68
    • (1991) Genomics , vol.10 , pp. 558-568
    • Maisonpierre, P.C.1    Le Beau, M.M.2    Espinosa III, R.3
  • 36
    • 0031002892 scopus 로고    scopus 로고
    • Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes
    • Fawcett JP, Aloyz R, McLean JH, et al. Detection of brain-derived neurotrophic factor in a vesicular fraction of brain synaptosomes. J Biol Chem 1997;272:8837-40
    • (1997) J Biol Chem , vol.272 , pp. 8837-8840
    • Fawcett, J.P.1    Aloyz, R.2    McLean, J.H.3
  • 37
    • 0026634815 scopus 로고
    • The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
    • DiStefano PS, Friedman B, Radziejewski C, et al. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron 1992;8: 983-93
    • (1992) Neuron , vol.8 , pp. 983-993
    • DiStefano, P.S.1    Friedman, B.2    Radziejewski, C.3
  • 38
    • 0025132860 scopus 로고
    • Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
    • Ernfors P, Wetmore C, Olson L, Persson H. Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron 1990;5:511-26
    • (1990) Neuron , vol.5 , pp. 511-526
    • Ernfors, P.1    Wetmore, C.2    Olson, L.3    Persson, H.4
  • 39
    • 0029854439 scopus 로고    scopus 로고
    • NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues
    • NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues. Neurochem Res 1996;21:929-38
    • (1996) Neurochem Res , vol.21 , pp. 929-938
    • Yamamoto, M.1    Sobue, G.2    Yamamoto, K.3    Terao, S.4    Mitsuma, T.5
  • 40
    • 0018343960 scopus 로고
    • The distribution of dorsal root axons in laminae I, II and III of the macaque spinal cord: A quantitative electron microscope study
    • Ralston HJ III, Ralston DD. The distribution of dorsal root axons in laminae I, II and III of the macaque spinal cord: A quantitative electron microscope study. J Comp Neurol 1979;184:643-84
    • (1979) J Comp Neurol , vol.184 , pp. 643-684
    • Ralston III, H.J.1    Ralston, D.D.2
  • 41
    • 0018758817 scopus 로고
    • Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers
    • Light AR, Perl ER. Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. J Comp Neurol 1979;186: 117-32
    • (1979) J Comp Neurol , vol.186 , pp. 117-132
    • Light, A.R.1    Perl, E.R.2
  • 42
    • 0018770078 scopus 로고
    • Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers
    • Light AR, Perl ER. Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers. J Comp Neurol 1979;186:133-50
    • (1979) J Comp Neurol , vol.186 , pp. 133-150
    • Light, A.R.1    Perl, E.R.2
  • 43
    • 0018763580 scopus 로고
    • Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn
    • Light AR, Trevino DL, Perl ER. Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn. J Comp Neurol 1979;186:151-72
    • (1979) J Comp Neurol , vol.186 , pp. 151-172
    • Light, A.R.1    Trevino, D.L.2    Perl, E.R.3
  • 44
    • 2442646665 scopus 로고    scopus 로고
    • A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
    • ALS CNTF Treatment Study Group. A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. Neurology 1996;46:1244-49
    • (1996) Neurology , vol.46 , pp. 1244-1249
  • 45
    • 9044219848 scopus 로고    scopus 로고
    • A placebo-controlled trial of recombinant human ciliary neurotrophic factor (rhCNTF) in amyotrophic lateral sclerosis
    • Miller RG, Petajan JH, Bryan WW, et al. A placebo-controlled trial of recombinant human ciliary neurotrophic factor (rhCNTF) in amyotrophic lateral sclerosis. Ann Neurol 1996;39:256-60
    • (1996) Ann Neurol , vol.39 , pp. 256-260
    • Miller, R.G.1    Petajan, J.H.2    Bryan, W.W.3
  • 46
    • 0030970888 scopus 로고    scopus 로고
    • New approaches to the treatment of ALS
    • Miller RG, Sufit R. New approaches to the treatment of ALS. Neurology 1997;48 (Suppl 4):28-32
    • (1997) Neurology , vol.48 , Issue.4 SUPPL. , pp. 28-32
    • Miller, R.G.1    Sufit, R.2
  • 47
    • 6844266272 scopus 로고    scopus 로고
    • Effect of recombinant human insulin-like growth factor-1 on progression of ALS. A placebo-controlled study
    • Lai EC, Felice KJ, Festoff BW, et al. Effect of recombinant human insulin-like growth factor-1 on progression of ALS. A placebo-controlled study. Neurology 1997;49:1621-30
    • (1997) Neurology , vol.49 , pp. 1621-1630
    • Lai, E.C.1    Felice, K.J.2    Festoff, B.W.3
  • 48
    • 0000337980 scopus 로고
    • A phase I/II study of recombinant human brain-derived neurotrophic factor in patients with amyotrophic lateral sclerosis
    • Bradley WG, Miami FL, the BDNF Trial Group. A phase I/II study of recombinant human brain-derived neurotrophic factor in patients with amyotrophic lateral sclerosis [abstract]. Ann Neurol 1995;38: 971
    • (1995) Ann Neurol , vol.38 , pp. 971
    • Bradley, W.G.1    Miami, F.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.