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Volumn 48, Issue 4 SUPPL. 4, 1997, Pages

New approaches to the treatment of ALS

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; BRAIN DERIVED NEUROTROPHIC FACTOR; GABAPENTIN; NEURITE PROMOTING FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4; PROTEASE NEXIN I; PROTEINASE INHIBITOR; RECOMBINANT SOMATOMEDIN C; RILUZOLE;

EID: 0030970888     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.48.4_suppl_4.28s     Document Type: Conference Paper
Times cited : (11)

References (35)
  • 1
    • 0027265313 scopus 로고
    • The natural history of amyotrophic lateral sclerosis (ALS)
    • Ringel SP, Murphy JR, Alderson MK, et al. The natural history of amyotrophic lateral sclerosis (ALS). Neurology 1993; 43:1316-1322.
    • (1993) Neurology , vol.43 , pp. 1316-1322
    • Ringel, S.P.1    Murphy, J.R.2    Alderson, M.K.3
  • 2
  • 3
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • Bensimon G, Lacomblez L, Meininger V, and the ALS/Riluzole Study Group. A controlled trial of riluzole in amyotrophic lateral sclerosis. N Engl J Med 1994;330:585-591.
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 4
    • 0029977337 scopus 로고    scopus 로고
    • Dose-ranging study of riluzole in amyotrophic lateral sclerosis
    • Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V, for the Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Lancet 1996;347:1425-1431.
    • (1996) Lancet , vol.347 , pp. 1425-1431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5
  • 5
    • 0029847118 scopus 로고    scopus 로고
    • Excitotoxicity hypothesis
    • Rothstein JD. Excitotoxicity hypothesis. Neurology 1996; 47(suppl 2):S19-S26.
    • (1996) Neurology , vol.47 , Issue.2 SUPPL.
    • Rothstein, J.D.1
  • 6
    • 0030026831 scopus 로고    scopus 로고
    • Superoxide dismutase and familial amyotrophic lateral sclerosis: New insights into mechanisms and treatments
    • Brown RH. Superoxide dismutase and familial amyotrophic lateral sclerosis: new insights into mechanisms and treatments. Ann Neurol 1996;39:147-157.
    • (1996) Ann Neurol , vol.39 , pp. 147-157
    • Brown, R.H.1
  • 7
    • 0029808008 scopus 로고    scopus 로고
    • Molecular genetic basis of familial ALS
    • Siddique T, Nijhawan D, Hentati A. Molecular genetic basis of familial ALS. Neurology 1996;47(suppl 2):S27-S35.
    • (1996) Neurology , vol.47 , Issue.2 SUPPL.
    • Siddique, T.1    Nijhawan, D.2    Hentati, A.3
  • 8
    • 0029155790 scopus 로고
    • Motor neurone disease
    • Pall HS. Motor neurone disease. Rev Clin Gerontol 1995;5: 303-311.
    • (1995) Rev Clin Gerontol , vol.5 , pp. 303-311
    • Pall, H.S.1
  • 9
    • 0030029277 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: Current and future treatment strategies
    • Festoff BW. Amyotrophic lateral sclerosis: current and future treatment strategies. Drugs 1996;51:28-44.
    • (1996) Drugs , vol.51 , pp. 28-44
    • Festoff, B.W.1
  • 10
    • 0027762836 scopus 로고
    • The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1
    • Martin D, Thompson MA, Nadler JV. The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur J Pharmacol 1993; 250:473-476.
    • (1993) Eur J Pharmacol , vol.250 , pp. 473-476
    • Martin, D.1    Thompson, M.A.2    Nadler, J.V.3
  • 11
    • 0027213025 scopus 로고
    • Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
    • Debono M-W, Le Guern J, Canton T, Doble A, Pradier L. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 1993;235:283-289.
    • (1993) Eur J Pharmacol , vol.235 , pp. 283-289
    • Debono, M.-W.1    Le Guern, J.2    Canton, T.3    Doble, A.4    Pradier, L.5
  • 12
    • 0022384359 scopus 로고
    • 2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission - II: Biochemical properties
    • Benavides J, Camelin JC, Mitrani N, et al. 2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission - II: biochemical properties. Neuropharmacology 1985;24:1085-1092.
    • (1985) Neuropharmacology , vol.24 , pp. 1085-1092
    • Benavides, J.1    Camelin, J.C.2    Mitrani, N.3
  • 13
    • 0028058808 scopus 로고
    • Antagonism by riluzole of entry of calcium evoked by NMDa and veratridine in rat cultured granule cells: Evidence for a dual mechanism of action
    • Hubert JP, Delumeau JC, Glowinski J, Prémont J, Doble A. Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of action. Br J Pharmacol 1994;113:261-267.
    • (1994) Br J Pharmacol , vol.113 , pp. 261-267
    • Hubert, J.P.1    Delumeau, J.C.2    Glowinski, J.3    Prémont, J.4    Doble, A.5
  • 14
    • 0028365121 scopus 로고
    • Block of the rat brain IIA sodium channel α subunit by the neuroprotective drug riluzole
    • Hebert T, Drapeau P, Pradier L, Dunn RJ. Block of the rat brain IIA sodium channel α subunit by the neuroprotective drug riluzole. Mol Pharmacol 1994;45:1055-1060.
    • (1994) Mol Pharmacol , vol.45 , pp. 1055-1060
    • Hebert, T.1    Drapeau, P.2    Pradier, L.3    Dunn, R.J.4
  • 15
    • 0029021812 scopus 로고
    • Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures
    • Estevez AG, Stutzmann J-M, Barbeito L. Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures. Eur J Pharmacol 1995;280:47-53.
    • (1995) Eur J Pharmacol , vol.280 , pp. 47-53
    • Estevez, A.G.1    Stutzmann, J.-M.2    Barbeito, L.3
  • 17
    • 0029113872 scopus 로고
    • Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity
    • Rothstein JD, Kuncl RW. Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity. J Neurochem 1995;65:643-651.
    • (1995) J Neurochem , vol.65 , pp. 643-651
    • Rothstein, J.D.1    Kuncl, R.W.2
  • 18
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • Gurney ME, Curring FB, Zhai P, et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 1996;39:147-157.
    • (1996) Ann Neurol , vol.39 , pp. 147-157
    • Gurney, M.E.1    Curring, F.B.2    Zhai, P.3
  • 19
    • 0028142392 scopus 로고
    • El Escorial World Federation of Neurology Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis
    • World Federation of Neurology Research Group on Neuromuscular Diseases. El Escorial World Federation of Neurology Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis. J Neurol Sci 1994;124(suppl):96-107.
    • (1994) J Neurol Sci , vol.124 , Issue.SUPPL. , pp. 96-107
  • 20
    • 0028084990 scopus 로고
    • Riluzole for the treatment of amyotrophic lateral sclerosis - Too soon to tell?
    • Rowland LP. Riluzole for the treatment of amyotrophic lateral sclerosis - too soon to tell? [editorial]. N Engl J Med 1994;330: 636-637.
    • (1994) N Engl J Med , vol.330 , pp. 636-637
    • Rowland, L.P.1
  • 21
    • 0029965967 scopus 로고    scopus 로고
    • Effects of the novel neuroprotective agent, riluzole, on human brain function and behavior: I. Double-blind, placebo-controlled EEG mapping and psychometric studies under normoxia
    • Saletu B, Grünberger J, Anderer P, Linzmayer L. Effects of the novel neuroprotective agent, riluzole, on human brain function and behavior: I. Double-blind, placebo-controlled EEG mapping and psychometric studies under normoxia. Methods Find Exp Clin Pharmacol 1996;18:55-66.
    • (1996) Methods Find Exp Clin Pharmacol , vol.18 , pp. 55-66
    • Saletu, B.1    Grünberger, J.2    Anderer, P.3    Linzmayer, L.4
  • 22
    • 0027762580 scopus 로고
    • Insulin-like growth factor-I: Potential for treatment of motor neuronal disorders
    • Lewis ME, Neff NT, Contreras PC, et al. Insulin-like growth factor-I: potential for treatment of motor neuronal disorders. Exp Neurol 1993;124:73-88.
    • (1993) Exp Neurol , vol.124 , pp. 73-88
    • Lewis, M.E.1    Neff, N.T.2    Contreras, P.C.3
  • 23
    • 0027527205 scopus 로고
    • Insulin-like growth factors: Putative muscle-derived trophic agents that promote motoneuron survival
    • Neff NT, Prevette D, Houenou LJ, et al. Insulin-like growth factors: putative muscle-derived trophic agents that promote motoneuron survival. J Neurobiol 1993;24:1578-1588.
    • (1993) J Neurobiol , vol.24 , pp. 1578-1588
    • Neff, N.T.1    Prevette, D.2    Houenou, L.J.3
  • 24
    • 10244237798 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor-I in ALS: Description of a double-blind, placebo-controlled study
    • Lange DJ, Felice KJ, Festoff BW, et al. Recombinant human insulin-like growth factor-I in ALS: description of a double-blind, placebo-controlled study. Neurology 1996;47(suppl 2): S93-S95.
    • (1996) Neurology , vol.47 , Issue.2 SUPPL.
    • Lange, D.J.1    Felice, K.J.2    Festoff, B.W.3
  • 25
    • 0023195073 scopus 로고
    • A rating scale for amyotrophic lateral sclerosis: Description and preliminary experience
    • Appel V, Stewart SS, Smith G, Appel SH. A rating scale for amyotrophic lateral sclerosis: description and preliminary experience. Ann Neurol 1987;22:328-333.
    • (1987) Ann Neurol , vol.22 , pp. 328-333
    • Appel, V.1    Stewart, S.S.2    Smith, G.3    Appel, S.H.4
  • 26
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan Q, Elliot J, Snider WD. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 1992;360:753-755.
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliot, J.2    Snider, W.D.3
  • 27
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner M, Holtmann B, Kolbeck R, et al. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1992;360:757-759.
    • (1992) Nature , vol.360 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3
  • 28
    • 0028853885 scopus 로고
    • Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion
    • Novikov L, Novikova L, Kellerth JO. Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion. Neurosci Lett 1995;200:45-48.
    • (1995) Neurosci Lett , vol.200 , pp. 45-48
    • Novikov, L.1    Novikova, L.2    Kellerth, J.O.3
  • 29
    • 0000337980 scopus 로고
    • Subcutaneous administration of recombinant human methionyl-brain-derived neurotrophic factor (r-meth-huBDNF) in amyotrophic lateral sclerosis
    • BDNF Study Group. Subcutaneous administration of recombinant human methionyl-brain-derived neurotrophic factor (r-meth-huBDNF) in amyotrophic lateral sclerosis [abstract]. Ann Neurol 1995;38:971.
    • (1995) Ann Neurol , vol.38 , pp. 971
  • 30
    • 0028823728 scopus 로고
    • Potential treatment of amyotrophic lateral sclerosis with gabapentin: A hypothesis
    • Welty DF, Schielke GP, Rothstein JD. Potential treatment of amyotrophic lateral sclerosis with gabapentin: a hypothesis. Ann Pharmacother 1995;29:1164-1167.
    • (1995) Ann Pharmacother , vol.29 , pp. 1164-1167
    • Welty, D.F.1    Schielke, G.P.2    Rothstein, J.D.3
  • 31
    • 10544254257 scopus 로고    scopus 로고
    • Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis
    • in press
    • Miller RG, Moore D, Young LA, et al. Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. Neurology [in press].
    • Neurology
    • Miller, R.G.1    Moore, D.2    Young, L.A.3
  • 32
    • 0028822549 scopus 로고
    • Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor
    • Li L, Wu W, Lin L-F H, Lei M, Oppenheim RW, Houenou LJ. Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci USA 1995;92:9771-9775.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9771-9775
    • Li, L.1    Wu, W.2    Lin, L.-F.H.3    Lei, M.4    Oppenheim, R.W.5    Houenou, L.J.6
  • 33
    • 0029826989 scopus 로고    scopus 로고
    • Drug combination treatment in patients with ALS: Current status and future directions
    • Mitsumoto H, Olney RK. Drug combination treatment in patients with ALS: current status and future directions. Neurology 1996;47(suppl 2):S103-S107.
    • (1996) Neurology , vol.47 , Issue.2 SUPPL.
    • Mitsumoto, H.1    Olney, R.K.2
  • 34
    • 0026729250 scopus 로고
    • Intrathecal thyrotropin-releasing hormone does not alter the progressive course of ALS: Experience with an intrathecal drug delivery system
    • Munsat TL, Taft J, Jackson IMD, et al. Intrathecal thyrotropin-releasing hormone does not alter the progressive course of ALS: experience with an intrathecal drug delivery system. Neurology 1992;42:1049-1053.
    • (1992) Neurology , vol.42 , pp. 1049-1053
    • Munsat, T.L.1    Taft, J.2    Imd, J.3
  • 35
    • 15844381714 scopus 로고    scopus 로고
    • Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
    • Aebischer P, Schleup M, Déglon N, et al. Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. Nature Med 1996;2:696-699.
    • (1996) Nature Med , vol.2 , pp. 696-699
    • Aebischer, P.1    Schleup, M.2    Déglon, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.