Elevated neointimal endothelin-1 in transplantation-associated arteriosclerosis of renal allograft recipients

Kidney International

Volumn 54, Issue 3, 1998, Pages 960-971

  Simonson, M S ^a   Emancipator, S N ^a   Knauss, T ^a   Hricik, D E ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Arterial remodeling; Chronic rejection; Endothelin; Neointima; Renal transplantation; Transplant vasculopathy

Indexed keywords

ENDOTHELIN 1;

ADULT; ARTERIOSCLEROSIS; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY TRANSPLANTATION; MALE; MITOGENESIS; MORPHOMETRICS; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0031656052     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00063.x     Document Type: Article

References (40)

1. D. Gordon Transplant Arteriosclerosis, V. Fuster R. Ross E.J. Topol Atherosclerosis and Coronary Artery Disease 1996 Lippincott-Raven Philadelphia 715
2. N.L. Tilney W.D. Whitley J.R. Diamond J.W. Kupiec-Weglinski D.H. Adams Chronic rejection–An undefined conundrum Transplantation 52 1991 389 398
3. B. Watschinger M.H. Sayegh Endothelin in organ transplantation Am J Kidney Dis 27 1996 151 161
4. K.A. Porter Renal Transplantation, R.H. Heptinstall Pathology of the Kidney 1992 Little Brown Boston 1799
5. T.H. Hostetter Chronic transplant rejection Kidney Int 46 1994 266 279
6. M.J. Bia Nonimmunologic causes of late graft loss Kidney Int 47 1995 1470 1480
7. W.H. Hancock W. Whitley S. Tullius U. Heemann B. Wasowska W. Baldwin N. Tilney Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts Transplantation 56 1993 643 650
8. B.L. Kasiske R.S.N. Kalil H.S. Lee K.V. Rao Histopathologic findings associated with a chronic, progressive decline in renal allograft function Kidney Int 40 1991 514 524
9. R.N. Salomon C.C.W. Hughes F.J. Schoen D.D. Payne J.S. Pober P. Libby Human coronary transplantation-associated arteriosclerosis: Evidence for a chronic immune reaction to activated graft endothelial cells Am J Pathol 138 1991 791 798
10. C. Shi W.-S. Lee Q. He D. Zhang D.L. Fletcher J.B. Newell E. Haber Immunologic basis of transplant-associated arteriosclerosis Proc Natl Acad Sci USA 93 1996 4051 4056
11. S.G. Tullius U. Heemann W.W. Hancock H. Azuma N.L. Tilney Long-term kidney isografts develop functional and morphologic changes that mimic those of chronic allograft rejection Ann Surg 4 1994 425 435
12. M.S. Simonson Endothelins: Multifunctional renal peptides Physiol Rev 73 1993 375 411
13. D.E. Kohan Endothelins and the kidney: Physiology and pathophysiology Am J Kidney Dis 22 1993 493 510
14. B. Watschinger M.H. Sayegh W.W. Hancock M.E. Russell Up-regulation of endothelin-1 mRNA and peptide expression in rat cardiac allografts with rejection and arteriosclerosis Am J Pathol 146 1995 1065 1072
15. R. Forbes P. Cernacek S.-X. Zheng M. Gomersall R. Guttmann Increased endothelin expression in a rat cardiac allograft rejection model of chronic vascular rejection Transplantation 61 1996 791 797
16. K.C. Nadeau H. Azuma B. Watschinger M.H. Sayegh N.L. Tilney Endothelin and cytokine gene expression in rat renal allografts undergoing chronic failure J Am Soc Nephrol 6 1995 666 abstract
17. H. Azuma K. Nadeau M. Takada H.S. MacKenzie N.L. Tilney Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/reperfusion injury of a single kidney Transplantation 64 1997 190 197
18. K.C. Nadeau H. Azuma N.L. Tilney Sequential cytokine dynamics in chronic rejection of rat renal allografts: Roles for cytokines and RANTES and MCP-1 Proc Natl Acad Sci 92 1995 8729 8733
19. A. Giad D. Saleh M. Yanagisawa R.D. Clarke Forbes Endothelin-1 immunoreactivity and mRNA in the transplanted human heart Transplantation 59 1995 1308 1313
20. P. Aarnio P. Tukiainen E. Taskinen A. Harjula F. Fyhrquist Endothelin in bronchoalveolar lavage fluid is increased in lung-transplanted patients Scand J Thor Cardiovasc Surg 30 1996 113 116
21. B. Watschinger A. Vychytil M. Attar D. Wagner M. Schuller E. Hartter W. Ulrich Pattern of endothelin immunostaining during rejection episodes after kidney transplantation Clin Nephrol 41 1994 86 93
22. H. Schersten T. Hedner C. McGregor V.D. Miller G. Martensson G. Riise F.N. Nilsson Increased levels of endothelin-1 in bronchoalveolar lavage fluid of patients with lung allografts J Thorac Cardiovasc Surg 111 1996 253 258
23. B. Watschinger A. Vychytil M. Schuller E. Hartter O. Traindl A pathophysiologic role of endothelin in acute vascular rejection after renal transplantation Transplantation 52 1991 743 746
24. 4 Transplant Proc 28 1996 304 305
25. S. Ravalli M. Szaboles A. Albala R.E. Michler P.J. Cannon Increased immunoreactive endothelin-1 in human transplant coronary artery disease Circulation 94 1996 2096 2102
26. K. Solez R. Axelsen H. Benediktsson J. Burdick A. Cohen R. Colvin B. Croker D. Droz M. Dunnill P. Halloran P. Hayry J. Jennette P. Keown N. Marcussen M. Mihatsch K. Morozumi B.D. Myers C. Nast S. Olsen L. Racusen E. Ramos S. Rosen D. Sachs D. Salomon F. Sanfilippo R. Verani E. VonWillebrand Y. Yamaguchi International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology Kidney Int 44 1993 411 422
27. P.S. Russell C.M. Chase H.J. Winn R.B. Colvin Coronary atherosclerosis in transplanted mouse hearts: Time course and immunogenetic and immunopathological considerations Am J Pathol 144 1994 260 274
28. K. Takahasi Y. Sawasaki Rare spontaneously transformed human endothelial cell line provides useful research tool In Vitro Cell Dev Biol 28A 1992 380 382
29. P.J. Schultz P.E. Dicorleto B.J. Silver H.E. Abboud Mesangial cells express PDGF mRNAs and proliferate in response to PDGF Am J Physiol 255 1988 F674 F684
30. D.E. Kohan Endothelins in the normal and diseased kidney J Kidney Dis 29 1997 2 26
31. E.R. Levin Endothelins N Engl J Med 333 1995 356 363
32. A.D. Kirk L.M. Jacobson D.M. Heisey N.A. Fass H.W. Sollinger J.D. Pirsch Posttransplant diastolic hypertension Transplantation 64 1997 1716 1720
33. T.J. Rabelink K.A.H. Kaasjager P. Boer E.G. Stroes B. Braam H.A. Koomans Effects of endothelin-1 on renal function in humans: Implications for physiology and pathophysiology Kidney Int 46 1994 376 381
34. T.E. Bunchman C.A. Brookshire Cyclosporine-induced synthesis of endothelin by cultured human endothelial cells J Clin Invest 88 1991 310 314
35. S. Iwasaki T. Homma V. Kon Site specific regulation in the kidney of endothelin and its receptor subtypes by cyclosporine Kidney Int 45 1994 592 597
36. N. Perico J. Dadan G. Remuzzi Endothelin mediates the renal vasoconstriction induced by cyclosporine in the rat J Am Soc Nephrol 1 1990 76 83
37. J.D. Conger D.M. Lanese Effects of endothelin receptor antagonist on cyclosporine-induced vasoconstriction in isolated rat renal arterioles J Clin Invest 91 1993 2144 2149
38. M. Takeda M.D. Breyer T.D. Noland T. Homma R.L. Hoover T. Inagami V. Kon Endothelin-1 receptor antagonist: Effects on endothelin- and cyclosporine-treated mesangial cells Kidney Int 42 1992 1713 1719
39. V. Kon M. Sugiura T. Inagami B.R. Harvie I. Ichikawa R.L. Hoover Role of endothelin in cyclosporine-induced glomerular dysfunction Kidney Int 37 1990 1487 1491
40. F. Stockenhuber M. Gottsauner-Wolf L. Marosi B. Liebisch R.W. Kurz P. Balcke Plasma levels of endothelin in chronic renal failure and after renal transplantation: Impact on hypertension and cyclosporin A-associated nephrotoxicity Clin Sci 82 1992 255 258