Aldosterone responsiveness of A6 cells is restored by cloned rat mineralocorticoid receptor

American Journal of Physiology

Volumn 274, Issue 1 PART 1, 1998, Pages

  Chen, Sei Y U ^b   Wang, Jian ^b   Liu, Weihong ^b   Pearce, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Dexamethasone; Glucocorticoid receptor; Nuclear localization; Short circuit current; Sodium transport; Species specificity; Transcriptional activation

Indexed keywords

11,17 DIHYDROXY 6 METHYL 17 (1 PROPYNYL)ANDROSTA 1,4,6 TRIENE 3 ONE; 11,17-DIHYDROXY-6-METHYL-17-(1-PROPYNYL)ANDROSTA-1,4,6-TRIENE-3-ONE; ALDOSTERONE; ANDROSTANE DERIVATIVE; MINERALOCORTICOID RECEPTOR; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE POTENTIAL; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; KINETICS; MOLECULAR CLONING; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RAT;

ALDOSTERONE; ANDROSTANOLS; ANIMALS; CELL LINE; CLONING, MOLECULAR; KINETICS; MEMBRANE POTENTIALS; POLYMERASE CHAIN REACTION; RATS; RECEPTORS, MINERALOCORTICOID; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0031606030     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Arriza, J. L., R. B. Simerly, L. W. Swanson, and R. M. Evans. The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1: 887-900, 1988.
2. Arriza, J. L., C. Weinberger, G. Cerelli, T. M. Glaser, B. L. Handelin, D. E. Housman, and R. M. Evans. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237: 268-275, 1987.
3. Bastl, C. P., G. Schulman, and E. J. Cragoe. Low-dose glucocorticoids stimulate electroneutral NaCl absorption in rat colon. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F1027-F1038, 1989.
4. Blazer, Y. B., M. Geheb, A. Preston, J. Handler, and M. Cox. Aldosterone-induced proteins in renal epithelia. Biochim. Biophys. Acta 719: 158-161, 1982.
5. Blendy, J., T. Cole, S. Berger, D. Rudolph, W. Schmid, and G. Schutz. Analysis of glucocorticoid and cAMP signaling by gene targeting (Abstract). Proc. Int. Congr. Endocrinol. 10th San Francisco, CA 1996, p. 701.
6. Bohen, S. P., and K. R. Yamamoto. Isolation of Hsp90 mutants by screening for decreased steroid receptor function. Proc. Natl. Acad. Sci. USA 90: 11424-11428, 1993.
7. Burnstein, K. L., C. M. Jewell, and J. A. Cidlowski. Evaluation of the role of ligand and thermal activation of specific DNA binding by in vitro synthesized human glucocorticoid receptor. Mol. Endocrinol. 5: 1013-1022, 1991.
8. Chalfie, M., Y. Tu, G. Euskirchen, W. W. Ward, and D. C. Prasher. Green fluorescent protein as a marker for gene expression. Science 263: 802-805, 1994.
9. Chen, S.-Y., G.-Q. Yu, J. Wang, and D. Pearce. Androgen and glucocorticoid receptor heterodimer formation: a possible mechanism for mutual inhibition of transcriptional activity. J. Biol. Chem. 272: 14087-14092, 1997.
10. Claire, M., B. Machard, M. Lombes, M. E. Oblin, J. P. Bonvalet, and N. Farman. Aldosterone receptors in A6 cells: physicochemical characterization and autoradiographic study. Am. J. Physiol. 257 (Cell Physiol. 26): C665-C677, 1989.
11. Cole, T. J., J. A. Blendy, A. P. Monaghan, K. Krieglstein, W. Schmid, A. Aguzzi, G. Fantuzzi, E. Hummler, K. Unsicker, and G. Schutz. Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9: 1608-1621, 1995.
12. Csikos, T., J. Tay, and M. Danielsen. Expression of the Xenopus laevis mineralocorticoid receptor during metamorphosis. Recent Prog. Horm. Res. 50: 393-396, 1995.
13. Diamond, M. I., J. N. Miner, S. K. Yoshinaga, and K. R. Yamamoto. Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science 249: 1266-1272, 1990.
14. Edwards, C. R. W., P. M. Stewart, D. Burt, L. Brett, M. A. McIntyre, W. S. Sutanto, E. R. DeKloet, and C. Monder. Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 2: 986-989, 1988.
15. Ferrari, P., V. R. Obeyesekere, K. Li, R. C. Wilson, M. I. New, J. W. Funder, and Z. S. Krozowski. Point mutations abolish 11β-hydroxysteroid dehydrogenase type II activity in three families with the congenital syndrome of apparent mineralocorticoid excess. Mol. Cell. Endocrinol. 119: 21-24, 1996.
16. Funder, J. W. Mineralocorticoids, glucocorticoids, receptors and response elements. Science 259: 1132-1133, 1993.
17. Funder, J. W., P. T. Pearce, K. Myles, and L. P. Roy. Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action. FASEB J. 4: 3234-3238, 1990.
18. Funder, J. W., P. T. Pearce, R. Smith, and A. I. Smith. Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242: 583-585, 1988.
19. Galfre, G., and C. Milstein. Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol. 73B: 3-46, 1981.
20. Handler, J. S., F. M. Perkins, and J. P. Johnson. Hormone effects on transport in cultured epithelia with high electrical resistance. Am. J. Physiol. 240 (Cell Physiol. 9): C103-C105, 1981.
21. Heck, S., M. Kullmann, A. Gast, H. Ponta, H. J. Rahmsdorf, P. Herrlich, and A. C. Cato. A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J. 13: 4087-4095, 1994.
22. Hong, H., K. Kohli, A. Trivedi, D. L. Johnson, and M. R. Stallcup. GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. Proc. Natl. Acad. Sci. USA 93: 4948-4952, 1996.
23. Htun, H., J. Barsony, I. Renyi, D. L. Gould, and G. L. Hager. Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera. Proc. Natl. Acad. Sci. USA 93: 4845-4850, 1996.
24. Joels, M., and E. R. de Kloet. Coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. Neuroendocrinology 55: 344-350, 1992.
25. Joels, M., and E. R. de Kloet. Effect of corticosteroid hormones on electrical activity in rat hippocampus. J. Steroid Biochem. Mol. Biol. 40: 83-86, 1991.
26. Joels, M., and E. R. de Kloet. Mineralocorticoid receptor-mediated changes in membrane properties of rat CA1 pyramidal neurons in vitro. Proc. Natl. Acad. Sci. USA 87: 4495-4498, 1990.
27. Kralli, A., S. P. Bohen, and K. R. Yamamoto. LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones. Proc. Natl. Acad. Sci. USA 92: 4701-4705, 1995.
28. Kralli, A., and K. R. Yamamoto. An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones. J. Biol. Chem. 271: 17152-17156, 1996.
29. Kumar, V., and P. Chambon. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell 55: 145-156, 1988.
30. Laplace, J. R., R. F. Husted, and J. B. Stokes. Cellular responses to steroids in the enhancement of Na transport by rat collecting duct cells in culture: differences between glucocorticoid and mineralocorticoid hormones. J. Clin. Invest. 90: 1370-1378, 1992.
31. Liu, W., J. Wang, N. K. Sauter, and D. Pearce. Steroid receptor heterodimerization demonstrated in vitro and in vivo. Proc. Natl. Acad. Sci. USA 92: 12480-12484, 1995.
32. Liu, W., J. Wang, G. Yu, and D. Pearce. Steroid receptor transcriptional synergy is potentiated by disruption of the DNA-binding domain dimer interface. Mol. Endocrinol. 10: 1399-1406, 1996.
33. Lowy, M. T. Quantification of type I and II adrenal steroid receptors in neuronal, lymphoid and pituitary tissues. Brain Res. 503: 191-197, 1989.
34. Marver, D., and J. P. Kokko. Renal target sites and the mechanism of action of aldosterone. Miner. Electrolyte Metab. 9: 1-18, 1983.
35. Mune, T., F. M. Rogerson, H. Nikkila, A. K. Agarwal, and P. C. White. Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase. Nat. Genet. 10: 394-399, 1995.
36. Naray-Fejes-Toth, A., and T. G. Fejes. Glucocorticoid receptors mediate mineralocorticoid-like effects in cultured collecting duct cells. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F672-F678, 1990.
37. Onate, S. A., S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270: 1354-1357, 1995.
38. Pearce, D. A mechanistic basis for distinct mineralocorticoid and glucocorticoid receptor transcriptional specificities. Steroids 59: 153-159, 1994.
39. Pearce, D., and K. R. Yamamoto. Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element. Science 259: 1161-1165, 1993.
40. Picard, D., V. Kumar, P. Chambon, and K. R. Yamamoto. Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors. Cell Regul. 1: 291-299, 1990.
41. Picard, D. and K. R. Yamamoto. Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. BMBO J. 6: 3333-3340, 1987.
42. Pratt, W. B., and M. J. Welsh. Chaperone functions of the heat shock proteins associated with steroid receptors. Semin. Cell Biol. 5: 83-93, 1994.
43. Ribeiro, R., R. R. Cavalieri, N. Lomri, C. M. Rahmaoui, J. D. Baxter, and B. F. Scharschmidt. Thyroid hormone export regulates cellular hormone content and response. J. Biol. Chem. 271: 17147-17151, 1996.
44. Rupprecht, R., J. L. Arriza, D. Spengler, J. M. Reul, R. M. Evans, F. Holsboer, and K. Damm. Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor. Mol. Endocrinol. 7: 597-603, 1993.
45. Sato, A., and J. Funder. High glucose stimulates aldosterone-induced hypertrophy via type I mineralocorticoid receptors in neonatal rat cardiomyocytes. Endocrinology. 137: 4145-4153, 1996.
46. Schena, M., and K. R. Yamamoto. Mammalian glucocorticoid receptor derivatives enhance transcription in yeast. Science 241: 965-967, 1988.
47. + transport in A6 cells is mediated via glucocorticoid receptors. Am. J. Physiol. 264 (Cell Physiol. 33): C875-C884, 1993.
48. Stoos, B. A., A. Naray-Fejes-Toth, O. A. Carretero, S. Ito, and G. Fejes-Toth. Characterization of a mouse cortical collecting duct cell line. Kidney Int. 39: 1168-1175, 1991.
49. Strahle, U., M. Boshart, G. Klock, F. Stewart, and G. Schutz. Glucocorticoid- and progesterone-specific effects are determined by differential expression of the respective hormone receptors. Nature 339: 629-632, 1989.
50. Trapp, T., R. Rupprecht, M. Castren, J. M. Reul, and F. Holsboer. Heterodimerization between mineralocorticoid and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron 13: 1457-1462, 1994.
51. Truss, M., and M. Beato. Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endoer. Rev. 14: 459-479, 1993.
52. Turnamian, S. G., and H. J. Binder. Aldosterone and glucocorticoid receptor-specific agonists regulate ion transport in rat proximal colon. Am. J. Physiol. 238 (Gastrointest. Liver Physiol. 21): G492-G498, 1990.
53. + transport in cultured kidney cells. Am. J. Physiol. 242 (Renal Fluid Electrolyte Physiol. 11): F610-F619, 1982.
54. Wilson, R. C., Z. S. Krozowski, K. Li, V. R. Obeyesekere, A. M. Razzaghy, M. D. Harbison, J. Q. Wei, C. H. Shackleton, J. W. Funder, and M. I. New. A mutation in the HSD11B2 gene in a family with apparent mineralocorticoid excess. J. Clin. Endocrinol. Metab. 80: 2263-2266, 1995.
55. Yamamoto, K. R., D. Pearce, J. Thomas, and J. N. Miner. Combinatorial regulation at a mammalian composite response element. In: Transcriptional Regulation, edited by S. L. McKnight and K. R. Yamamoto. Cold Spring Harbor, NY: Cold Spring Harbor, 1992, p. 1169-1192.