Comparison of Benzodiazepine-Like Compounds Using Topological Analysis and Genetic Algorithms

SAR and QSAR in Environmental Research

Volumn 8, Issue 3-4, 1998, Pages 195-232

  Meurice, N ^a   Leherte, L ^a   Vercauteren, D P ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

Author keywords

genetic algorithms; graph comparison; pharmacophore elucidation; Three dimensional electron density; topological analysis

Indexed keywords

ELECTRON DENSITY MEASUREMENT;

BENZODIAZEPINES; DIFFERENT RESOLUTIONS; ELECTRON DENSITY MAPS; GRAPH COMPARISON; PHARMACOPHORE ELUCIDATION; PHARMACOPHORES; RESOLUTION LEVEL; THREE-DIMENSIONAL ELECTRON DENSITY; THREE-DIMENSIONAL ELECTRONS; TOPOLOGICAL ANALYSIS;

GRAPH THEORY;

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE;

ALGORITHM; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRON; GENETIC PROCEDURES; REVIEW; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; BENZODIAZEPINES; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; GENETIC TECHNIQUES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031601522     PISSN: 1062936X     EISSN: 1029046X     Source Type: Journal    
DOI: 10.1080/10629369808039141     Document Type: Article

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