A 6β-(thiaheptanamide) derivative of estradiol as inhibitor of 17β-hydroxysteroid dehydrogenase type 1

Journal of Steroid Biochemistry and Molecular Biology

Volumn 64, Issue 1-2, 1998, Pages 83-90

  Poirier, Donald ^a   Dionne, Patricia ^a   Auger, Serge ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

7 (3,17BETA DIHYDROXY 1,3,5(10) ESTRATRIEN 6BETA YL) 7 THIAHEPTANAMIDE; ESTRADIOL DERIVATIVE; OXIDOREDUCTASE; OXIDOREDUCTASE INHIBITOR; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG; ANTIESTROGEN; DRUG DERIVATIVE; ENZYME INHIBITOR; ESTRADIOL; ESTRONE; HYDROXYSTEROID DEHYDROGENASE; N BUTYL N METHYL 7 (3',17'BETA DIHYDROXY 1',3',5'(10') ESTRATRIENE 6'BETA YL) 7 THIAHEPTANAMIDE; N-BUTYL-N-METHYL-7-(3',17'BETA-DIHYDROXY-1',3',5'(10')-ESTRATRIENE-6'BETA-YL)-7-THIAHEPTANAMIDE;

ARTICLE; CHIRALITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYMATIC ASSAY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLACENTA; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; METABOLISM; PREGNANCY; STEREOISOMERISM; SYNTHESIS;

17-HYDROXYSTEROID DEHYDROGENASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; ESTRADIOL; ESTRADIOL ANTAGONISTS; ESTRADIOL CONGENERS; ESTROGEN ANTAGONISTS; ESTRONE; FEMALE; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; PLACENTA; PREGNANCY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031596753     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(97)00136-2     Document Type: Article

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