Functional coupling of the NK1 tachykinin receptor to phospholipase D in Chinese hamster ovary cells and astrocytoma cells

Journal of Neurochemistry

Volumn 70, Issue 5, 1998, Pages 2091-2098

  Torrens, Yvette ^a   Beaujouan, Jean Claude ^a   Saffroy, Monique ^a   Glowinski, Jacques ^a   Tencé, Martine ^a  

^a l'alimentation et l'Environnement   (France)

Author keywords

Chinese hamster ovary cells; Human astrocytoma cells; NK1 receptor; Phospholipase D; Protein kinase C; Substance P

Indexed keywords

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; ARACHIDONIC ACID; CYCLIC AMP; INOSITOL PHOSPHATE; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ A [4-10]; NOLPITANTIUM; PHOSPHOLIPASE D; PROTEIN KINASE C; SENKTIDE; SUBSTANCE P; TRITIUM; CALCIUM; DRUG DERIVATIVE; GLYCEROPHOSPHOLIPID; GUANINE NUCLEOTIDE BINDING PROTEIN; MYRISTIC ACID; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOL; SUBSTANCE P, PRO(9); SUBSTANCE P, PRO(9)-; TACHYKININ;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; ASTROCYTOMA CELL; CHO CELL; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME ASSAY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; ASTROCYTOMA; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; ENZYME ACTIVATION; HAMSTER; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; TRITIUM;

ANIMALS; ASTROCYTOMA; CALCIUM; CHO CELLS; CRICETINAE; CYCLIC AMP; ENZYME ACTIVATION; GLYCEROPHOSPHOLIPIDS; GTP-BINDING PROTEINS; HUMANS; MYRISTIC ACID; PHOSPHATIDIC ACIDS; PHOSPHATIDYLCHOLINES; PHOSPHOLIPASE D; PROTEIN KINASE C; RATS; RECEPTORS, NEUROKININ-1; SUBSTANCE P; TACHYKININS; TUMOR CELLS, CULTURED;

EID: 0031596744     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70052091.x     Document Type: Article

References (40)

1. Alexander S. P. H. and Peters J. A. (1997) Receptor and ion channel nomenclature. Trends Pharmacol. Sci. (Suppl.), 71-72.
2. Bligh E. G. and Dyer W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917.
3. Brodbeck R., Sachais B. C., and Krause J. E. (1995) Residue 78 in the second transmembrane domain of the neurokinin-1 receptor is important in coupling high affinity agonist binding to multiple second messenger responses. Mol. Pharmacol. 47, 1065-1071.
4. Chabre M. (1990) Aluminofluoride and beryllofluoride complexes: new phosphate analogs in enzymology. Trends Biol. Sci. 15, 6-10.
5. Cockroft S. (1992) G-protein-regulated phospholipases C, D and A2-mediated signaling in neutrophils. Biochim. Biophys. Acta 1113, 135-160.
6. Cockroft S. (1996) ARF-regulated phospholipase D: a potential role in membrane traffic. Chem. Phys. Lipids 80, 59-80.
7. Colley W. C., Sung T. C., Roll R., Jenco J., Hammond S. M., Altshuller Y., Bar-Sagi D., Morris A. J., and Frohman M. A. (1997) Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr. Biol. 7, 191-201.
8. Davis P. D., Hill C. H., Keech E., Lawton G., Nixon J. S., Sedwiwick A. D., Wadsworth L., Westmacott D., and Wilkinson S. E. (1989) Potent selective inhibitors of protein kinase C. FEBS Lett. 259, 61-63.
9. 2+ concentration in mouse astrocytes by NK1 tachykinin and adenosine agonists. J. Neurochem. 57, 2026-2035.
10. Denizot F. and Lang R. (1986) Rapid colorimetric assay for cell growth and survival. J. Immunol. Methods 89, 271-277.
11. Desagher S., Cordier J., Glowinski J., and Tencé M. (1997) Endothelin stimulates phospholipase D in striatal astrocytes. J. Neurochem. 68, 78-87.
12. Eistetter H. R., Mills A., Brewster R., Alouani S., Rambosson C., and Kawashima E. (1992) Functional characterization of neurokinin-1 receptors on human U373MG astrocytoma cells. Glia 6, 89-95.
13. Exton J. H. (1994) Phosphatidylcholine breakdown and signal transduction. Biochim. Biophys. Acta 1212, 26-42.
14. Exton J. H. (1997) New developments in phospholipase D. J. Biol. Chem. 272, 15579-15582.
15. Garcia M., Sakamolo K., Shigekawa M., Nakanishi S., and Ito S. (1994) Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of substance P receptor. Biochem. Pharmacol. 48, 1735-1741.
16. Gjertsen B. T., Mellgren G., Otten A., Maronde E., Genieser H. G., Jastorff B., Vintermyr O. K., McKnight G. S., and Doskeland S. O. (1995) Novel (Rp)cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. J. Biol. Chem. 270, 20599-20607.
17. Hammond S. M., Altshuller Y. M., Sung T. C., Rudge S. A., Rose K., Engebrecht J. A., Morris A. J., and Frohman M. A. (1995) Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J. Biol. Chem. 270, 29640-29643.
18. Hartung H. P., Heininger K., Schäffer B., and Toyka K. (1988) Substance P and astrocytes: stimulation of the cyclooxygenase pathway of arachidonic acid metabolism. FASEB J. 2, 48-51.
19. Hermans E., Jeanjean A. P., Fardin V., Pradier L., Garret C., Laduron P. M., Octave J. N., and Maloteaux J. M. (1993) Interaction of the substance P receptor antagonist RP 67580 with the rat brain NK-1 receptor expressed in transfected CHO cells. Eur. J. Pharmacol. 245, 43-50.
20. 1 tachykinin receptor in the astrocytoma cell line U 373 MG. J. Neurochem. 60, 868-876.
21. Klein J., Chalifa V., Liscovitch M., and Löffelholz K. (1995) Role of phospholipase D activation in nervous system physiology and pathophysiology. J. Neurochem. 65, 1445-1454.
22. Krause J. E., Blount P., and Sachais B. S. (1994) Molecular biology of receptors, in The Tachykinin Receptors (Buck D.H., ed), pp. 165-218. Humana Press, Totowa, New Jersey.
23. Lee C. M., Tung W. L., and Young J. D. (1992) Tachykinin-stimulated inositol phospholipid hydrolysis and taurine release from human astrocytoma cells. J. Neurochem. 59, 406-414.
24. Mantyh P. W., Pinnock R. D., Downes C. P., Goedert M., and Hunt S. P. (1984) Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. Nature 309, 795-797.
25. Mittal R., Reza Ahmadian M., Goody R. S., and Wittinghofer A. (1996) Formation of a transition-state analog of the ras GTPase reaction by Ras.GDP, tetrafluoroaluminate, and GTPase-activating proteins. Science 273, 115-117.
26. Mochizuki-Oda N., Nakajima Y., Nakanishi S., and Ito S. (1994) Characterization of the substance P receptor-mediated calcium influx in cDNA transfected Chinese hamster ovary cells. J. Biol. Chem. 269, 9651-9658.
27. Moolenaar W. H. (1994) LPA: a novel lipid mediator with diverse biological actions. Trends Cell. Biol. 4, 213-219.
28. Nakajima Y., Tsuchida K., Negishi M., Ito S., and Nakanishi S. (1992) Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells. J. Biol. Chem. 267, 2437-2442.
29. Nishizuka Y. (1995) Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9, 484-496.
30. Otsuka M. and Yoshioka K. (1993) Neurotransmitter functions of mammalian tachykinins. Physiol. Rev. 73, 229-308.
31. 9]-substance P is a potent and selective ligand of NK-1 tachykinin receptors. J. Neurochem. 56, 879-889.
32. Pradier L., Heuillet E., Hubert J. P., Laville M., Le Guern S., and Doble A. (1993) Substance P-evoked calcium mobilization and ionic current activation in the human astrocytoma cell line U 373 MG: pharmacological characterization. J. Neurochem. 61, 1850-1858.
33. Sagan S., Chassaing G., Pradier L., and Lavielle S. (1996) Tachykinin peptides affect differently the second messenger pathways after binding to CHO-expressed human NK1 receptors. J. Pharmacol. Exp. Ther. 27, 1-6.
34. Singer W. D., Brown H. A., Jiang X., and Sternweis P. C. (1996) Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activity. J. Biol. Chem. 271, 4505-4510.
35. Takeda Y., Blount P., Sachais B. S., Hershey A. D., Raddatz R., and Krause J. E. (1992) Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in Chinese hamster ovary cells and evidence for differential stimulation of inositol 1,4,5-trisphosphate and cyclic AMP second messenger responses. J. Neurochem. 59, 740-745.
36. Tencé M., Torrens Y., Beaujouan J. C., and Glowinski J. (1996) Substance P stimulates phospholipase D in Chinese hamster ovary cells expressing the NK1 tachykinin receptors. Soc. Neurosci. Abstr. 22, 160.
37. Thompson N. T., Garland L. G., and Bonser R. W. (1993) Phospholipase D: regulation and functional significance. Adv. Pharmacol. 24, 199-238.
38. Torrens Y., Beaujouan J. C., Saffroy M., Daguet de Montety M. C., Bergström L., and Glowinski J. (1986) Substance P receptors in primary cultures of cortical astrocytes from the mouse. Proc. Natl. Acad. Sci. USA 83, 9216-9220.
39. Torrens Y., Beaujouan J.-C., Saffroy M., and Glowinski J. (1995) Involvement of septide-sensitive tachykinin receptors in inositol phospholipid hydrolysis in the rat urinary bladder. Peptides 16, 587-594.
40. Womack M. D., MacDermott A. B., and Jessel T. M. (1988) Sensory transmitters regulate intracellular calcium in dorsal horn neurons. Nature 334, 351-353.