(±)-3-[4-(2-Dimethylamino-1-methylethoxy)-phenyl]- 1H-pyrazolo[3,4-B]pyridine-1-acetatic acid (Y-25510) stimulates de production of IL-1β and IL-6 at the level of messenger RNA expression in cultured human monocytes

International Journal of Immunopharmacology

Volumn 18, Issue 12, 1996, Pages 719-728

  Kusuhara, Hidenobu ^a   Komatsu, Hirotsugu ^a   Hisadome, Masao ^a   Ikeda, Yoshifumi ^a  

^a Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

IL 1 ; IL 6; mRNA expression; NF B; Y 25510

Indexed keywords

3 [4 (2 DIMETHYLAMINO 1 METHYLETHOXY)PHENYL] 1H PYRAZOLO[3,4 B]PYRIDINE 1 ACETIC ACID; CYCLOHEXIMIDE; IMMUNOMODULATING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; UNCLASSIFIED DRUG; DEXAMETHASONE; INTERLEUKIN 1; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MONONUCLEAR CELL; PRIORITY JOURNAL; BIOSYNTHESIS; CULTURE MEDIUM; GENETICS; METABOLISM; MONOCYTE;

CULTURE MEDIA; CYCLOHEXIMIDE; DEXAMETHASONE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MONOCYTES; PYRAZOLES; PYRIDINES; RNA, MESSENGER; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TUMOR CELLS, CULTURED;

EID: 0030299075     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(97)85554-3     Document Type: Article

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