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Volumn 5, Issue 5, 1998, Pages 261-269

Clearance of [125I]-tumor necrosis factor-α from the brain into the blood after intracerebroventricular injection in rats

Author keywords

Brain; Cytokine; Tumor necrosis factor alpha

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA; LIPOPOLYSACCHARIDE; RADIOACTIVE IODINE;

EID: 0031595690     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000026346     Document Type: Article
Times cited : (36)

References (59)
  • 1
    • 0029398824 scopus 로고
    • Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries
    • Kossmann T, Hans VH, Imhof HG, Stocker R, Grob P, Trentz O, Morganti-Kossman C: Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries. Shock 1995;4:311-317.
    • (1995) Shock , vol.4 , pp. 311-317
    • Kossmann, T.1    Hans, V.H.2    Imhof, H.G.3    Stocker, R.4    Grob, P.5    Trentz, O.6    Morganti-Kossman, C.7
  • 2
    • 0025946766 scopus 로고
    • Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury
    • McClain C, Cohen D, Phillips R, Ott L, Young B: Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury. J Lab Clin Med 1991;118:225-231.
    • (1991) J Lab Clin Med , vol.118 , pp. 225-231
    • McClain, C.1    Cohen, D.2    Phillips, R.3    Ott, L.4    Young, B.5
  • 3
    • 0028364659 scopus 로고
    • Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue
    • Shohami E, Novikov M, Bass R, Yamin A, Gallily R: Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue. J Cereb Blood Flow Metab 1994;14:615-619.
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 615-619
    • Shohami, E.1    Novikov, M.2    Bass, R.3    Yamin, A.4    Gallily, R.5
  • 8
    • 0025362271 scopus 로고
    • Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6
    • De Simone MG, Sironi M, De Luigi A, Manfridi A, Mantovani A, Ghezzi P: Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6. J Exp Med 1990;171:1773-1778.
    • (1990) J Exp Med , vol.171 , pp. 1773-1778
    • De Simone, M.G.1    Sironi, M.2    De Luigi, A.3    Manfridi, A.4    Mantovani, A.5    Ghezzi, P.6
  • 10
    • 0029919042 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) is secreted from the brain after intracerebroventricular injection of IL-1β in rats
    • Romero LI, Kakucska I, Lechan RM, Reichlin S: Interleukin-6 (IL-6) is secreted from the brain after intracerebroventricular injection of IL-1β in rats. Am J Physiol 1996;270:R518-R524.
    • (1996) Am J Physiol , vol.270
    • Romero, L.I.1    Kakucska, I.2    Lechan, R.M.3    Reichlin, S.4
  • 11
    • 85047678427 scopus 로고    scopus 로고
    • 125I-labelled interleukin-6 from brain into blood following intracerebroventricular injection in rats
    • 125I-labelled interleukin-6 from brain into blood following intracerebroventricular injection in rats. Endocrinology 1997;138: 4830-4836.
    • (1997) Endocrinology , vol.138 , pp. 4830-4836
    • Chen, G.1    Castro, W.L.2    Chow, H.-H.3    Reichlin, S.4
  • 12
    • 9844249495 scopus 로고    scopus 로고
    • Intracerebroventricular injection of interleukin-1 stimulates the release of high levels of interleukin-6 into peripheral blood in the monkey (abstract P3-292)
    • Minneapolis, The Endocrine Society
    • Xiao E, Xia L, Ferin M, Wardlaw SL: Intracerebroventricular injection of interleukin-1 stimulates the release of high levels of interleukin-6 into peripheral blood in the monkey (abstract P3-292). Program 79th Annual Meeting. Minneapolis, The Endocrine Society, 1997, p 509.
    • (1997) Program 79th Annual Meeting , pp. 509
    • Xiao, E.1    Xia, L.2    Ferin, M.3    Wardlaw, S.L.4
  • 13
    • 0027058881 scopus 로고
    • Increased circulating interleukin-1 and interleukin-6 after intracerebroventricular injection of lipopolysaccharide
    • Gottschall PE, Komaki G, Arimura A: Increased circulating interleukin-1 and interleukin-6 after intracerebroventricular injection of lipopolysaccharide. Neuroendocrinology 1992; 56:935-938.
    • (1992) Neuroendocrinology , vol.56 , pp. 935-938
    • Gottschall, P.E.1    Komaki, G.2    Arimura, A.3
  • 14
    • 0028819533 scopus 로고
    • Central endotoxin induces different patterns of interleukin (IL)-1β and IL-6 messenger ribonucleic acid expression and IL-6 secretion in the brain and periphery
    • De Simoni MG, Del Bo R, De Luigi A, Simard S, Forloni G: Central endotoxin induces different patterns of interleukin (IL)-1β and IL-6 messenger ribonucleic acid expression and IL-6 secretion in the brain and periphery. Endocrinology 1995;136:897-902.
    • (1995) Endocrinology , vol.136 , pp. 897-902
    • De Simoni, M.G.1    Del Bo, R.2    De Luigi, A.3    Simard, S.4    Forloni, G.5
  • 15
    • 0027365705 scopus 로고
    • Kinetics of systemic and intrahypothalamic IL-6 and tumor necrosis factor during endotoxin fever in guinea pigs
    • Roth J, Conn CA, Kluger MJ, Zeisberger E: Kinetics of systemic and intrahypothalamic IL-6 and tumor necrosis factor during endotoxin fever in guinea pigs. Am J Physiol 1993;265: R653-R658.
    • (1993) Am J Physiol , vol.265
    • Roth, J.1    Conn, C.A.2    Kluger, M.J.3    Zeisberger, E.4
  • 16
    • 0026004784 scopus 로고
    • Inflammatory cells and the hypermetabolism of head injury
    • Robertson CS: Inflammatory cells and the hypermetabolism of head injury. J Lab Clin Med 1991;118:205.
    • (1991) J Lab Clin Med , vol.118 , pp. 205
    • Robertson, C.S.1
  • 17
  • 18
    • 0018974044 scopus 로고
    • Role of the central nervous system in acute-phase responses to leukocytic pyrogen
    • Turchik JB, Bornstein DL: Role of the central nervous system in acute-phase responses to leukocytic pyrogen. Infect Immun 1980;30:439-444.
    • (1980) Infect Immun , vol.30 , pp. 439-444
    • Turchik, J.B.1    Bornstein, D.L.2
  • 19
    • 0024377089 scopus 로고
    • Mediation of anorexia by human recombinant tumor necrosis factor through a peripheral action in the rat
    • Bodnar RJ, Pasternak GW, Mann PE, Paul D, Warren R, Donner DB: Mediation of anorexia by human recombinant tumor necrosis factor through a peripheral action in the rat. Cancer Res 1989;49:6280-6284.
    • (1989) Cancer Res , vol.49 , pp. 6280-6284
    • Bodnar, R.J.1    Pasternak, G.W.2    Mann, P.E.3    Paul, D.4    Warren, R.5    Donner, D.B.6
  • 20
    • 0027169378 scopus 로고
    • Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1
    • Kakucska I, Qi Y, Clark BD, Lechan RM: Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1. Endocrinology 1993;133: 815-821.
    • (1993) Endocrinology , vol.133 , pp. 815-821
    • Kakucska, I.1    Qi, Y.2    Clark, B.D.3    Lechan, R.M.4
  • 21
    • 0026638409 scopus 로고
    • Inflammatory cytokines within the central nervous system: Sources, function, and mechanism of action
    • Benveniste EN: Inflammatory cytokines within the central nervous system: Sources, function, and mechanism of action. Am J Physiol 1992; 263:C1-C16.
    • (1992) Am J Physiol , vol.263
    • Benveniste, E.N.1
  • 22
    • 0029048538 scopus 로고
    • Proinflammatory cytokines as pathogenetic mediators in the central nervous system
    • Faggioni R, Benigni F, Ghezzi P: Proinflammatory cytokines as pathogenetic mediators in the central nervous system. Neuroimmuno-modulation 1995;2:2-15.
    • (1995) Neuroimmuno-modulation , vol.2 , pp. 2-15
    • Faggioni, R.1    Benigni, F.2    Ghezzi, P.3
  • 23
    • 0027214546 scopus 로고
    • Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: Comparison with interleukin-1 family and interleukin-6
    • Gatti S, Bartfai T: Induction of tumor necrosis factor-alpha mRNA in the brain after peripheral endotoxin treatment: Comparison with interleukin-1 family and interleukin-6. Brain Res 1993;624:291-294.
    • (1993) Brain Res , vol.624 , pp. 291-294
    • Gatti, S.1    Bartfai, T.2
  • 24
    • 0028800715 scopus 로고
    • Cytokines and the nervous system. I. Expression and recognition
    • Hopkins SJ, Rothwell NJ: Cytokines and the nervous system. I. Expression and recognition. Trends Neurosci 1995;18:83-88.
    • (1995) Trends Neurosci , vol.18 , pp. 83-88
    • Hopkins, S.J.1    Rothwell, N.J.2
  • 25
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative disease
    • McGeer PL, McGeer EG: The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative disease. Brain Res Rev 1995;21:195-218.
    • (1995) Brain Res Rev , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 26
    • 0027970546 scopus 로고
    • Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain
    • Schöbitz B, De Kloet ER, Holsboer F: Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Prog Neurobiol 1994;44:397-432.
    • (1994) Prog Neurobiol , vol.44 , pp. 397-432
    • Schöbitz, B.1    De Kloet, E.R.2    Holsboer, F.3
  • 27
    • 0025309598 scopus 로고
    • WEHI 164 subclone 13 assay for TNF: Sensitivity, specificity and reliability
    • Eskandart MK, Nguyen DT, Kunkel SL, Remick DG: WEHI 164 subclone 13 assay for TNF: Sensitivity, specificity and reliability. Immunol Invest 1990;19:69-79.
    • (1990) Immunol Invest , vol.19 , pp. 69-79
    • Eskandart, M.K.1    Nguyen, D.T.2    Kunkel, S.L.3    Remick, D.G.4
  • 28
    • 0028117042 scopus 로고
    • Effect of arsenic exposure on alveolar macrophage function. 1. Effect of soluble As(III) and AS(V)
    • Lantz RC, Parliman G, Chen GJ, Carter DE: Effect of arsenic exposure on alveolar macrophage function. 1. Effect of soluble As(III) and AS(V). Environ Res 1994;67:183-195.
    • (1994) Environ Res , vol.67 , pp. 183-195
    • Lantz, R.C.1    Parliman, G.2    Chen, G.J.3    Carter, D.E.4
  • 29
    • 0000517316 scopus 로고
    • Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit
    • Bradbury MW, Cserr HF, Westrop RJ: Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit. Am J Physiol 1981; 240:F329-F336.
    • (1981) Am J Physiol , vol.240
    • Bradbury, M.W.1    Cserr, H.F.2    Westrop, R.J.3
  • 30
    • 1842715270 scopus 로고
    • Drainage of interstitial fluid from different regions of rat brain
    • Szentistvanyi I, Patlak CS, Ellis RA: Drainage of interstitial fluid from different regions of rat brain. Am J Physiol 1984;246:F835-F844.
    • (1984) Am J Physiol , vol.246
    • Szentistvanyi, I.1    Patlak, C.S.2    Ellis, R.A.3
  • 31
    • 0025992189 scopus 로고
    • Albumin outflow into deep cervical lymph from different regions of rabbit brain
    • Yamada S, DePasquale M, Patlak CS, Cserr HF: Albumin outflow into deep cervical lymph from different regions of rabbit brain. Am J Physiol 1991;261:H1197-H1204.
    • (1991) Am J Physiol , vol.261
    • Yamada, S.1    DePasquale, M.2    Patlak, C.S.3    Cserr, H.F.4
  • 32
    • 0025729615 scopus 로고
    • Distribution of extracellular tracers in perivascular spaces of the rat brain
    • Ichimura T, Fraser PA, Cserr HF: Distribution of extracellular tracers in perivascular spaces of the rat brain. Brain Res 1991;545:103-113.
    • (1991) Brain Res , vol.545 , pp. 103-113
    • Ichimura, T.1    Fraser, P.A.2    Cserr, H.F.3
  • 33
    • 0015939506 scopus 로고
    • 14C]inulin after intrathecal injection
    • 14C]inulin after intrathecal injection. Brain Res 1973; 52:323-332.
    • (1973) Brain Res , vol.52 , pp. 323-332
    • Bass, N.H.1    Lundborg, P.2
  • 34
    • 0013826669 scopus 로고
    • Potassium exchange between cerebrospinal fluid, plasma and brain
    • Cserr H: Potassium exchange between cerebrospinal fluid, plasma and brain. Am J Physiol 1965;209:1219-1226.
    • (1965) Am J Physiol , vol.209 , pp. 1219-1226
    • Cserr, H.1
  • 35
    • 0028135126 scopus 로고
    • Prediction of brain delivery of ofloxacin, a new quinolone, in the human from animal data
    • Kawakami J, Yamamoto K, Sawada Y, Iga T: Prediction of brain delivery of ofloxacin, a new quinolone, in the human from animal data. J Pharmacokinet Biopharm 1994;22:207-227.
    • (1994) J Pharmacokinet Biopharm , vol.22 , pp. 207-227
    • Kawakami, J.1    Yamamoto, K.2    Sawada, Y.3    Iga, T.4
  • 37
    • 0028049995 scopus 로고
    • Penetration of interleukin-6 across the murine bloodbrain barrier
    • Banks WA, Kastin AJ, Gutierrez EG: Penetration of interleukin-6 across the murine bloodbrain barrier. Neurosci Lett 1994;179:53-56.
    • (1994) Neurosci Lett , vol.179 , pp. 53-56
    • Banks, W.A.1    Kastin, A.J.2    Gutierrez, E.G.3
  • 39
    • 0026929035 scopus 로고
    • Drainage of brain extracellular fluid into blood and deep cervical lymph and its immunological significance
    • Cserr HF, Harling-Berg CJ, Knopf PM: Drainage of brain extracellular fluid into blood and deep cervical lymph and its immunological significance. Brain Pathol 1992;2:269-276.
    • (1992) Brain Pathol , vol.2 , pp. 269-276
    • Cserr, H.F.1    Harling-Berg, C.J.2    Knopf, P.M.3
  • 40
    • 0029042781 scopus 로고
    • Physiology and immunology of lymphatic drainage of interstitial and cerebrospinal fluid from the brain
    • Knopf PM, Cserr HF, Nolan SC, Wu T-Y, Harling-Berg CJ: Physiology and immunology of lymphatic drainage of interstitial and cerebrospinal fluid from the brain. Neuropathol Appl Neurobiol 1995;21:175-180.
    • (1995) Neuropathol Appl Neurobiol , vol.21 , pp. 175-180
    • Knopf, P.M.1    Cserr, H.F.2    Nolan, S.C.3    Wu, T.-Y.4    Harling-Berg, C.J.5
  • 41
    • 0026476657 scopus 로고
    • Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: A new view
    • Cserr HF, Knopf PM: Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: A new view. Immunol Today 1992;13:507-512.
    • (1992) Immunol Today , vol.13 , pp. 507-512
    • Cserr, H.F.1    Knopf, P.M.2
  • 42
    • 0026444002 scopus 로고
    • Afferent and efferent arms of the humoral immune response to CSF-administered albumins in a rat model with normal blood-brain barrier permeability
    • Cserr HF, DePasquale M, Harling-Berg CJ, Park JT, Knopf PM: Afferent and efferent arms of the humoral immune response to CSF-administered albumins in a rat model with normal blood-brain barrier permeability. J Neuroimmunol 1992;41:195-202.
    • (1992) J Neuroimmunol , vol.41 , pp. 195-202
    • Cserr, H.F.1    DePasquale, M.2    Harling-Berg, C.J.3    Park, J.T.4    Knopf, P.M.5
  • 43
    • 0026774536 scopus 로고
    • Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sites
    • Gordon LB, Knopf PM, Cserr HF: Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sites. J Neuroimmunol 1992;40:81-88.
    • (1992) J Neuroimmunol , vol.40 , pp. 81-88
    • Gordon, L.B.1    Knopf, P.M.2    Cserr, H.F.3
  • 44
    • 0026643572 scopus 로고
    • Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system
    • Andersson P-B, Perry VH, Gordon S: Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system. J Exp Med 1992;176:255-259.
    • (1992) J Exp Med , vol.176 , pp. 255-259
    • Andersson, P.-B.1    Perry, V.H.2    Gordon, S.3
  • 45
    • 0001139213 scopus 로고
    • Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus
    • Lieberman AP, Pitha PM, Shin HS, Shin ML: Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc Natl Acad Sci 1989;86:6348-6352.
    • (1989) Proc Natl Acad Sci , vol.86 , pp. 6348-6352
    • Lieberman, A.P.1    Pitha, P.M.2    Shin, H.S.3    Shin, M.L.4
  • 46
    • 0027198202 scopus 로고
    • Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1
    • Romero LI, Schettini G, Lechan RM, Dinarello CA, Reichlin S: Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology 1993;57:892-897.
    • (1993) Neuroendocrinology , vol.57 , pp. 892-897
    • Romero, L.I.1    Schettini, G.2    Lechan, R.M.3    Dinarello, C.A.4    Reichlin, S.5
  • 48
    • 0029560472 scopus 로고
    • Interleukin-6 mRNA expression by cortical neurons in culture: Evidence for neuronal sources of interleukin-6 production in the brain
    • Ringheim GE, Burgher KL, Heroux JA: Interleukin-6 mRNA expression by cortical neurons in culture: Evidence for neuronal sources of interleukin-6 production in the brain. J Neuroimmunol 1995;63:113-123.
    • (1995) J Neuroimmunol , vol.63 , pp. 113-123
    • Ringheim, G.E.1    Burgher, K.L.2    Heroux, J.A.3
  • 49
    • 0027945999 scopus 로고
    • Regional induction of tumor necrosis factor-α expression in the mouse brain after systemic lipopolysaccharide administration
    • Breder CD, Hazuka C, Ghayur T, Klug C, Huginin M, Yasuda K, Teng M, Saper CB: Regional induction of tumor necrosis factor-α expression in the mouse brain after systemic lipopolysaccharide administration. Proc Natl Acad Sci USA 1994;91:11393-11397.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11393-11397
    • Breder, C.D.1    Hazuka, C.2    Ghayur, T.3    Klug, C.4    Huginin, M.5    Yasuda, K.6    Teng, M.7    Saper, C.B.8
  • 51
    • 0025213321 scopus 로고
    • Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis
    • Gijbels K, Van Damme J, Proost P, Put W, Carton H, Billiau A: Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis. Eur J Immunol 1990;20:233-235.
    • (1990) Eur J Immunol , vol.20 , pp. 233-235
    • Gijbels, K.1    Van Damme, J.2    Proost, P.3    Put, W.4    Carton, H.5    Billiau, A.6
  • 53
    • 0028930324 scopus 로고
    • Independent down-regulation of central and peripheral tumor necrosis factor production as a result of lipopolysaccharide tolerance in mice
    • Faggioni R, Fantuzzi G, Villa P, Buurman W, Tits LJH van, Ghezzi P: Independent down-regulation of central and peripheral tumor necrosis factor production as a result of lipopolysaccharide tolerance in mice. Infect Immun 1995;63:1473-1477.
    • (1995) Infect Immun , vol.63 , pp. 1473-1477
    • Faggioni, R.1    Fantuzzi, G.2    Villa, P.3    Buurman, W.4    Van Tits, L.J.H.5    Ghezzi, P.6
  • 54
    • 0032077552 scopus 로고    scopus 로고
    • Alternative pathways of neural control of the immune process
    • Reichlin S: Alternative pathways of neural control of the immune process. Ann NY Acad Sci 1998;840:301-316.
    • (1998) Ann NY Acad Sci , vol.840 , pp. 301-316
    • Reichlin, S.1
  • 55
    • 0030809678 scopus 로고    scopus 로고
    • Central nor-adrenergic system modulates plasma interleukin-6 production by peripheral interleukin-1
    • Huang QH, Takaki A, Arimura A: Central nor-adrenergic system modulates plasma interleukin-6 production by peripheral interleukin-1. Am J Physiol 1997;273:R731-R738.
    • (1997) Am J Physiol , vol.273
    • Huang, Q.H.1    Takaki, A.2    Arimura, A.3
  • 56
    • 0029554162 scopus 로고
    • The autonomie nervous system as a communication channel between the brain and the immune system
    • Hori T, Katafuchi T, Take S, Shimizu N, Niijima A: The autonomie nervous system as a communication channel between the brain and the immune system. Neuroimmunomodulation 1995;2:203-215.
    • (1995) Neuroimmunomodulation , vol.2 , pp. 203-215
    • Hori, T.1    Katafuchi, T.2    Take, S.3    Shimizu, N.4    Niijima, A.5
  • 57
    • 0025639022 scopus 로고
    • Metabolic effects of cachectin/ tumor necrosis factor are modified by site of production
    • Tracey KJ, Morgello S, Koplin B, Fahey TJ III, Fox J, Aledo A: Metabolic effects of cachectin/ tumor necrosis factor are modified by site of production. J Clin Invest 1990;86:2014-2024.
    • (1990) J Clin Invest , vol.86 , pp. 2014-2024
    • Tracey, K.J.1    Morgello, S.2    Koplin, B.3    Fahey III, T.J.4    Fox, J.5    Aledo, A.6
  • 58
    • 0029610610 scopus 로고
    • Failure of current immunotherapy for malignant glioma. Tumor derived TGF-β, T-cell apoptosis, and the immune privilege of the brain
    • Weller M, Fontana A: Failure of current immunotherapy for malignant glioma. Tumor derived TGF-β, T-cell apoptosis, and the immune privilege of the brain. Brain Res Rev 1995;21: 128-151.
    • (1995) Brain Res Rev , vol.21 , pp. 128-151
    • Weller, M.1    Fontana, A.2
  • 59
    • 0028806803 scopus 로고
    • Cerebrovascular permeability to peptides: Manipulations of transport systems at the blood-brain barrier
    • Zlokovic BV: Cerebrovascular permeability to peptides: Manipulations of transport systems at the blood-brain barrier. Pharm Res 1995;12: 1395-1406.
    • (1995) Pharm Res , vol.12 , pp. 1395-1406
    • Zlokovic, B.V.1


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