Selective impairment of HCO3/--dependent pH(i) regulation by lysophosphatidylcholine in guinea pig ventricular myocardium

Cardiovascular Research

Volumn 37, Issue 1, 1998, Pages 179-186

  Yamaguchi, Seiichi ^a   Tamagawa, Masaji ^a   Nakajima, Nobuyuki ^a   Nakaya, Haruaki ^a  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Guinea pig papillary muscles; Intracellular Na+ activity; Intracellular pH; Ion selective microelectrode; Lysophosphatidylcholine; Na+ H+ exchange; Na+ HCO3 symport

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 5 (N,N HEXAMETHYLENE)AMILORIDE; AMMONIUM CHLORIDE; BICARBONATE; LYSOPHOSPHATIDYLCHOLINE; SODIUM ION; 5-(N,N-HEXAMETHYLENE)AMILORIDE; AMILORIDE; BICARBONATE SODIUM COTRANSPORTER; CARRIER PROTEIN; DRUG DERIVATIVE; PHOSPHATIDYLCHOLINE; SODIUM PROTON EXCHANGE PROTEIN;

ACIDIFICATION; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CELL PH; CONTROLLED STUDY; GUINEA PIG; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART PAPILLARY MUSCLE; HEART VENTRICLE; ION SELECTIVE ELECTRODE; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; ANIMAL; CELL MEMBRANE POTENTIAL; DRUG ANTAGONISM; DRUG EFFECT; HEART MUSCLE; HEART MUSCLE ISCHEMIA; INTRACELLULAR FLUID; METABOLISM; PH;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; AMILORIDE; ANIMALS; CARRIER PROTEINS; GUINEA PIGS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; LYSOPHOSPHATIDYLCHOLINES; MEMBRANE POTENTIALS; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PAPILLARY MUSCLES; PHOSPHATIDYLCHOLINES; SODIUM-BICARBONATE SYMPORTERS; SODIUM-HYDROGEN ANTIPORTER;

EID: 0031594599     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00203-4     Document Type: Article

References (49)

1. Corr P.B., Gross R.W., Sobel B.E. Amphipathic metabolites and membrane dysfunction in ischemic myocardium. Circ Res. 55:1984;135-154.
2. Corr PB, Yamada KA, Creer MH, Wu J, McHowat J, Yan GX. Amphipathic lipid metabolites and arrhythmias during ischemia. In: Zipes DP, Jalife J, editors. Cardiac Electrophysiology: From Cell to Bedside, 2nd ed. Philadelphia: W.B. Saunders Co., 1995: 182-203.
3. Corr P.B., Cain M.E., Witkowski F.X., Price D.A., Sobel B.E. Potential arrhythmogenic derangements in canine Purkinje fibers induced by lysophosphoglycerides. Circ Res. 44:1979;822-832.
4. Arnsdorf M.F., Sawicki G.J. The effects of lysophosphatidylcholine, a toxic metabolite of ischemia, on the components of cardiac excitability in sheep Purkinje fibers. Circ Res. 49:1981;16-30.
5. Pogwizd S.M., Onufer J.R., Kramer J.B., Sobel B.E., Corr P.B. Induction of delayed afterdepolarizations and triggered activity in canine Purkinje fibers by lysophosphoglycerides. Circ Res. 59:1986;416-426.
6. Nakaya H., Tohse N. Electrophysiological effects of acetyl glyceryl ether phosphorylcholine on cardiac tissues: comparison with lysophosphatidylcholine and long chain acyl carnitine. Br J Pharmacol. 89:1986;749-757.
7. Burnashev N.A., Undoviras A.I., Fleidervish I.A., Rosenshtraukh L.V. Ischemic poison lysophosphatidylcholine modifies heart sodium channels gating inducing long-lasting bursts of openings. Pflügers Arch. 415:1989;124-126.
8. Undrovinas A.I., Fleidervish I.A., Makielski J.C. Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine. Circ Res. 71:1992;1231-1241.
9. Sato T., Kiyosue T., Arita M. Inhibitory effects of palmitoylcarnitine and lysophosphatidylcholine on the sodium current of cardiac ventricular cells. Pflügers Arch. 420:1992;94-100.
10. Clarkson C.W., Ten Eick R.E. On the mechanism of lysophosphatidylchline-induced depolarization of cat ventricular myocardium. Circ Res. 52:1983;543-556.
11. Kiyosue T., Arita M. Effect of lysophosphatidylcholine on resting potassium conductance of isolated guinea pig ventricular cells. Pflügers Arch. 406:1986;296-302.
12. + channels in cardiac myocytes by free fatty acids. Circ Res. 67:1990;1040-1046.
13. + stimulated ATPase activity of rabbit and dog heart sarcolemma by lysophosphatidylcholine. Life Sci. 24:1979;1869-1876.
14. + ATPase. Am J Physiol. 247:1984;H840-H846.
15. i regulation. J Gen Physiol. 85:1985;43-64.
16. Vaughan-Jones R.D. An investigation of chloride-bicarbonate exchange in the sheep cardiac Purkinje fibre. J Physiol (Lond). 379:1986;377-406.
17. - symport in the sheep cardiac Purkinje fibre. J Physiol (Lond). 458:1992;289-306.
18. Lagadic-Gossmann D., Vaughan-Jones R.D., Buckler K.J. Adrenaline and extracellular ATP switch between two modes of acid extrusion in the guinea-pig ventricular myocytes. J Physiol (Lond). 458:1992;385-407.
19. i regulation by lysophosphatidylcholine in guinea pig ventricular myocardium. Circulation. 94(suppl):1996;I-307. Abstract.
20. i in quiescent ventricular myocardium. Cardiovasc Res. 28:1994;112-118.
21. Roos A., Boron W.F. Intracellular pH. Physiol Rev. 61:1981;296-434.
22. + exchange in the sheep cardiac Purkinje fibre. J Physiol (Lond). 428:1990;441-466.
23. i recovery from intracellular acidosis in guinea-pig ventricular myocytes. J Physiol (Lond). 458:1992;361-384.
24. Kleyman T.R., Cragoe E.J. Amiloride and its analogs as tools in the study of ion transport. J Membr Biol. 105:1988;1-21.
25. - exchange. J Gen Physiol. 96:1990;1247-1269.
26. 2, KCl, NaCl and HCl in dilute aqueous solutions. J Am Chem Soc. 72:1950;3680-3682.
27. Pitzer K.S., Mayorga G. Thermodynamics of electrolytes. II. Activity and osmotic coefficients for strong electrolytes with one or both ions univalent. J Phys Chem. 77:1973;2300-2308.
28. Shaikh N.A., Downar E. Time course of changes in porcine myocardial phospholipid levels during ischemia. Circ Res. 49:1981;316-325.
29. Corr P.B., Creer M.H., Yamada K.A., Saffitz J.E., Sobel B.E. Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation. J Clin Invest. 83:1989;927-936.
30. Gross R.W., Corr P.B., Lee B.I., Saffitz J.E., Crafford W.A. Jr., Sobel B.E. Incorporation of radiolabelled lysophosphatidylcholine into canine Purkinje fibers and ventricular muscle. Electrophysiological, biochemical, and autoradiographic correlations. Circ Res. 51:1982;27-32.
31. Saffitz J.E., Corr P.B., Lee B.I., Gross R.W., Williamson E.K., Sobel B.E. Pathophysiologic concentrations of lysophosphoglycerides quantified by electron microscopic autoradiography. Lab Invest. 50:1984;278-286.
32. Snyder D.W., Crafford W.A. Jr., Glashow J.L., Rankin D., Sobel B.E., Corr P.B. Lysophosphoglycerides in ischemic myocardial effluents and potentiation of their arrhythmogenic effects. Am J Physiol. 241:1981;H700-H707.
33. Akita H., Creer M.H., Yamada K.A., Sobel B.E., Corr P.B. Electrophysiologic effects of intracellular lysophosphoglycerides and their accumulation in cardiac lymph with myocardial ischemia in dogs. J Clin Invest. 78:1986;271-280.
34. Corr P.B., Snyder D.W., Lee B.I., Gross R.W., Keim C.R., Sobel B.E. Pathophysiological concentrations of lysophosphatides and the slow response. Am J Physiol. 243:1982;H187-H195.
35. Corr P.B., Yamada K.A., Creer M.H., Sharma A.D., Sobel B.E. Lysophosphoglycerides and ventricular fibrillation early after onset of ischemia. J Mol Cell Cardiol. 19(suppl 5):1987;S45-S53.
36. Fabiato A., Fabiato F. Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiac and skeletal muscles. J Physiol (Lond). 276:1978;233-255.
37. Magishi K., Kimura J., Kubo Y., Abiko Y. Exogenous lysophosphatidylcholine increases non-selective cation current in guinea-pig ventricular myocytes. Pflügers Arch. 432:1996;345-350.
38. + during myocardial ischemia. Am J Physiol. 268:1995;H1740-H1748.
39. Puceat M., Vassort G. Neurohumoral modulation of intracellular pH in the heart. Cardiovasc Res. 29:1995;178-183.
40. + exchange. Am J Physiol. 255:1988;H608-H615.
41. + exchange. Circ Res. 66:1990;1156-1159.
42. Khandoudi N., Laville M.P., Bril A. Protective effect of the sodium/hydrogen exchange inhibitors during global low-flow ischemia. J Cadiovasc Pharmacol. 28:1996;540-546.
43. Kugiyama K., Kerns S.A., Morrisett J.D., Roberts R., Henry P.D. Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature. 344:1990;160-162.
44. Yokoyama M., Hirata K., Miyake R., Akita H., Ishikawa Y., Fukuzaki H. Lysophosphatidylcholine: essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low density lipoprotein. Biochem Biophys Res Commun. 16:1990;301-308.
45. Flavahan N.A. Lysophosphatidylcholine modifies G protein-dependent signaling in porcine endothelial cells. Am J Physiol. 264:1993;H722-H727.
46. Fukao M., Hattori Y., Kanno M., Sakuma I., Kitabatake A. Evidence for selective inhibition by lysophosphatidylcholine of acetylcholine-induced endothelium-dependent hyperpolarization and relaxation in rat mesenteric artery. Br J Pharmacol. 116:1995;1541-1544.
47. ω-nitro-L-arginine/indomethacin-resistant endothelium-dependent relaxation in the porcine coronary artery. Circulation. 92:1995;3520-3526.
48. i in human subcutaneous small arteries. Am J Physiol. 268:1995;C580-C589.
49. 2+ mobilization from agonist-sensitive pools in bovine aortic endothelial cells. J Biol Chem. 265:1990;19071-19076.