Lymphoid hyperplasia, CD45RB(high) to CD45RB(low) T-cell imbalance, and suppression of type I diabetes mellitus result from TNF blockade in nod → NOD-scid adoptive T cell transfer

Diabetologia

Volumn 41, Issue 12, 1998, Pages 1502-1510

  Brown, G R ^a   Silva, M D ^b   Thompson, P A ^b   Beutler, B ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Autoimmunity; Cytokines; Immunoregulation; TNF; Type I diabetes mellitus

Indexed keywords

CD45 ANTIGEN; CYTOKINE; TUMOR NECROSIS FACTOR; BETA GALACTOSIDASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNITY; CELL INFILTRATION; CELL POPULATION; CELL PROTECTION; COMBINED IMMUNODEFICIENCY; FEMALE; GLUCOSURIA; HISTOCOMPATIBILITY; IMMUNE RESPONSE; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; KETOACIDOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE TRANSFER; LYMPHOID HYPERPLASIA; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SPLEEN CELL; WESTERN BLOTTING; ADOPTIVE TRANSFER; ANIMAL; CD4 CD8 RATIO; CYTOLOGY; DRUG ANTAGONISM; GENETICS; HYPERPLASIA; IMMUNOLOGY; LYMPHOCYTE; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PATHOLOGY; SPLEEN; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD45; BETA-GALACTOSIDASE; CD4-CD8 RATIO; DIABETES MELLITUS, TYPE 1; FEMALE; HYPERPLASIA; LYMPHOCYTES; MICE; MICE, INBRED NOD; MICE, SCID; SPLEEN; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031593867     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051097     Document Type: Article

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