Pharmacology of [3H]-pyrilamine binding and of the histamine-induced inositol phosphates generation, intracellular Ca2+-mobilization and cytokine release from human corneal epithelial cells

British Journal of Pharmacology

Volumn 125, Issue 6, 1998, Pages 1336-1344

  Sharif, N A ^a,b   Wiernas, T K ^a,b   Griffin, B W ^a,b   Davis, T L ^a  

^a ALCON RESEARCH LTD   (United States)

^b UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Calcium mobilization; Cornea; Corneal epithelial cells; Cytokines; Histamine; Matrix metalloproteases; PI turnover

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM ION; CLOBENPROPIT; COLLAGENASE; CYTOKINE; EGTAZIC ACID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; HISTAMINE RECEPTOR; INOSITOL PHOSPHATE; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MEPYRAMINE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C INHIBITOR; PROSTAGLANDIN E2; RANITIDINE; TRIPROLIDINE; TRITIUM; TUMOR NECROSIS FACTOR ALPHA; CALCIUM; INTERSTITIAL COLLAGENASE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL CULTURE; CELL FREE SYSTEM; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOKINE RELEASE; HUMAN; HUMAN CELL; LIGAND BINDING; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RADIOASSAY; RECEPTOR AFFINITY; SERUM; BIOSYNTHESIS; CORNEA; DRUG EFFECT; EPITHELIUM CELL; KINETICS; METABOLISM; SECRETION;

CALCIUM; CELLS, CULTURED; COLLAGENASES; CORNEA; CYTOKINES; DINOPROSTONE; EPITHELIAL CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTAMINE; HISTAMINE H1 ANTAGONISTS; HUMANS; INOSITOL PHOSPHATES; INTERLEUKIN-6; INTERLEUKIN-8; KINETICS; MATRIX METALLOPROTEINASE 1; PYRILAMINE; RECEPTORS, HISTAMINE H1; TRITIUM;

EID: 0031593805     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702194     Document Type: Article

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