-
1
-
-
0015895044
-
Malaria in the Australian Army in South Vietnam. Successful use of a proguanil-dapsone combination for chemoprophylaxis of chloroquine-resistant falciparum malaria
-
Black, R.H., 1973. Malaria in the Australian Army in South Vietnam. Successful use of a proguanil-dapsone combination for chemoprophylaxis of chloroquine-resistant falciparum malaria. Med. J. Aust. 1, 1265-1270.
-
(1973)
Med. J. Aust.
, vol.1
, pp. 1265-1270
-
-
Black, R.H.1
-
2
-
-
0017623896
-
Experimental studies of the potentiation of proguanil and pyrimethamine by dapsone using Plasmodium berghei in white mice
-
Black, R.H., Ray, A.P., 1977. Experimental studies of the potentiation of proguanil and pyrimethamine by dapsone using Plasmodium berghei in white mice. Ann. Trop. Med. Parasitol. 71, 131-139.
-
(1977)
Ann. Trop. Med. Parasitol.
, vol.71
, pp. 131-139
-
-
Black, R.H.1
Ray, A.P.2
-
3
-
-
0023275760
-
Human pharmacokinetics of proguanil and its metabolites
-
Bygbjerg, I., Ravn, P., Ronn, A., Flachs, H., Hvidberg, E.F., 1987. Human pharmacokinetics of proguanil and its metabolites. Trop. Med. Parasit. 38, 77-80.
-
(1987)
Trop. Med. Parasit.
, vol.38
, pp. 77-80
-
-
Bygbjerg, I.1
Ravn, P.2
Ronn, A.3
Flachs, H.4
Hvidberg, E.F.5
-
4
-
-
0029078941
-
Interactions of Atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro
-
Canfield, C.J., Pudney, M., Gutteridge, W.E., 1995. Interactions of Atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro. Exp. Parasitol. 80, 373-381.
-
(1995)
Exp. Parasitol.
, vol.80
, pp. 373-381
-
-
Canfield, C.J.1
Pudney, M.2
Gutteridge, W.E.3
-
5
-
-
0001316408
-
The treatment and prophylaxis of malaria
-
Wernsdorfer, W.H., McGregor, I. (Eds.), Churchill Livingstone, Edinburgh, London, Melbourne and New York
-
Desjardins, R.E., Doberstyn, E.B., Wernsdorfer, W.H., 1988. The treatment and prophylaxis of malaria. In: Wernsdorfer, W.H., McGregor, I. (Eds.), Malaria: Principles and Practice of Malariology, Vol. I. Churchill Livingstone, Edinburgh, London, Melbourne and New York.
-
(1988)
Malaria: Principles and Practice of Malariology
, vol.1
-
-
Desjardins, R.E.1
Doberstyn, E.B.2
Wernsdorfer, W.H.3
-
6
-
-
0028200291
-
Oxidative activation of proguanil and dapsone acetylation in Thai soldiers
-
Edstein, M.D., Shanks, G.D., Teja-Isavadharm, P., Rieckmann, K.H., Webster, H.K., 1994. Oxidative activation of proguanil and dapsone acetylation in Thai soldiers. Br. J. Clin. Pharmacol. 37, 67-70.
-
(1994)
Br. J. Clin. Pharmacol.
, vol.37
, pp. 67-70
-
-
Edstein, M.D.1
Shanks, G.D.2
Teja-Isavadharm, P.3
Rieckmann, K.H.4
Webster, H.K.5
-
7
-
-
0029815579
-
Proguanil polymorphism does not affect the antimalarial activity of proguanil combined with atovaquone in vitro
-
Edstein, M.D., Yeo, A.E.T., Kyle, D.E., Looareesuwan, S., Wilairatana, P., Rieckmann, K.H., 1996. Proguanil polymorphism does not affect the antimalarial activity of proguanil combined with atovaquone in vitro. Trans. Roy. Soc. Trop. Med. Hyg. 90, 418-421.
-
(1996)
Trans. Roy. Soc. Trop. Med. Hyg.
, vol.90
, pp. 418-421
-
-
Edstein, M.D.1
Yeo, A.E.T.2
Kyle, D.E.3
Looareesuwan, S.4
Wilairatana, P.5
Rieckmann, K.H.6
-
8
-
-
0014442219
-
Plasmodium berghei dihydrofolate reductase. Isolation, properties and inhibition by antifolates
-
Ferone, R., Burchall, J.J., Hitchings, G.H., 1969. Plasmodium berghei dihydrofolate reductase. Isolation, properties and inhibition by antifolates. Mol. Pharmacol. 5, 49-59.
-
(1969)
Mol. Pharmacol.
, vol.5
, pp. 49-59
-
-
Ferone, R.1
Burchall, J.J.2
Hitchings, G.H.3
-
9
-
-
0024516081
-
In vitro activity of antimalarial compounds on the exoerythrocytic stages of Plasmodium cynomolgi and P. knowlesi
-
Fisk, T.L., Millet, P., Collins, W.E., Nguyen-Dinh, P., 1988. In vitro activity of antimalarial compounds on the exoerythrocytic stages of Plasmodium cynomolgi and P. knowlesi. Am. J. Trop. Med. Hyg. 40, 235-239.
-
(1988)
Am. J. Trop. Med. Hyg.
, vol.40
, pp. 235-239
-
-
Fisk, T.L.1
Millet, P.2
Collins, W.E.3
Nguyen-Dinh, P.4
-
10
-
-
0026605065
-
Site of action of antimalarial hydroxynaphthoquinone, 2-(trans-4-(4′-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone (566C80)
-
Fry, M., Pudney, M., 1992. Site of action of antimalarial hydroxynaphthoquinone, 2-(trans-4-(4′-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone (566C80). Biochem. Pharmacol. 43, 1545-1553.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 1545-1553
-
-
Fry, M.1
Pudney, M.2
-
13
-
-
0025038681
-
The pharmacokinetics and activation of proguanil in man: Consequences of variability in drug metabolism
-
Helsby, N.A., Ward, S.A., Edwards, G., Howells, R.E., Breckenridge, A.M., 1990. The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism. Br. J. Clin. Pharmacol. 30, 593-598.
-
(1990)
Br. J. Clin. Pharmacol.
, vol.30
, pp. 593-598
-
-
Helsby, N.A.1
Ward, S.A.2
Edwards, G.3
Howells, R.E.4
Breckenridge, A.M.5
-
14
-
-
0013820394
-
Inhibition of folate biosynthesis and function as a basis for chemotherapy
-
Hitchings, G.H., Burchall, J.J., 1965. Inhibition of folate biosynthesis and function as a basis for chemotherapy. Adv. Enzymol. 27, 417-468.
-
(1965)
Adv. Enzymol.
, vol.27
, pp. 417-468
-
-
Hitchings, G.H.1
Burchall, J.J.2
-
15
-
-
0022261360
-
A comparison of the pyrimethamine and cycloguanil sensitivities of the pre-erythrocytic and erythrocytic stages of drug-sensitive and drug-resistant strains of Plasmodium yoelii
-
Howells, R.E., Gilles, H.M., Bent, N.S., 1985. A comparison of the pyrimethamine and cycloguanil sensitivities of the pre-erythrocytic and erythrocytic stages of drug-sensitive and drug-resistant strains of Plasmodium yoelii. Ann. Trop. Med. Parasitol. 79, 247-251.
-
(1985)
Ann. Trop. Med. Parasitol.
, vol.79
, pp. 247-251
-
-
Howells, R.E.1
Gilles, H.M.2
Bent, N.S.3
-
16
-
-
0026356884
-
566C80: A potent broad spectrum anti-infective agent with activity against malaria and opportunistic infections in AIDS patients
-
Hudson, A.T., Dickins, M., Ginger, C.D., Gutteridge, W.E., Holdich, T., Hutchinson, D.B.A., Pudney, M., Randall, A.W., Latter, V.S., 1991. 566C80: a potent broad spectrum anti-infective agent with activity against malaria and opportunistic infections in AIDS patients. Drugs Exp. Clin. Res. XVII, 427-435.
-
(1991)
Drugs Exp. Clin. Res.
, vol.17
, pp. 427-435
-
-
Hudson, A.T.1
Dickins, M.2
Ginger, C.D.3
Gutteridge, W.E.4
Holdich, T.5
Hutchinson, D.B.A.6
Pudney, M.7
Randall, A.W.8
Latter, V.S.9
-
17
-
-
0027288589
-
Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS
-
Hughes, W., Leoung, G., Kramer, F., Bozzette, S.A., Safrin, S., Frame, P., Clumeck, N., Masur, H., Lancaster, D., Chan, C., Lavelle, J., Rosenstock, J., Falloon, J., Feinberg, J., LaFon, S., Rogers, M., Sattler, F., 1993. Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS. Lancet 328, 1521-1527.
-
(1993)
Lancet
, vol.328
, pp. 1521-1527
-
-
Hughes, W.1
Leoung, G.2
Kramer, F.3
Bozzette, S.A.4
Safrin, S.5
Frame, P.6
Clumeck, N.7
Masur, H.8
Lancaster, D.9
Chan, C.10
Lavelle, J.11
Rosenstock, J.12
Falloon, J.13
Feinberg, J.14
LaFon, S.15
Rogers, M.16
Sattler, F.17
-
18
-
-
0025022006
-
Proguanil-sulphonamide for malaria prophylaxis
-
Karwacki, J.J., Shanks, G.D., Limsomwong, N., Singharaj, P., 1990. Proguanil-sulphonamide for malaria prophylaxis. Trans. R. Soc. Trop. Med. Hyg. 84, 55-57.
-
(1990)
Trans. R. Soc. Trop. Med. Hyg.
, vol.84
, pp. 55-57
-
-
Karwacki, J.J.1
Shanks, G.D.2
Limsomwong, N.3
Singharaj, P.4
-
19
-
-
0026779579
-
Efficacy of atovaquone in treatment of toxoplasmosis in patients with AIDS
-
Kovacs, J.A., 1992. Efficacy of atovaquone in treatment of toxoplasmosis in patients with AIDS. Lancet 340, 637-638.
-
(1992)
Lancet
, vol.340
, pp. 637-638
-
-
Kovacs, J.A.1
-
20
-
-
0018704491
-
Synchronisation of Plasmodium falciparum erythrocytic stages in culture
-
Lambros, C., Vanderberg, J.P., 1979. Synchronisation of Plasmodium falciparum erythrocytic stages in culture. J. Parasitol. 65, 418-420.
-
(1979)
J. Parasitol.
, vol.65
, pp. 418-420
-
-
Lambros, C.1
Vanderberg, J.P.2
-
21
-
-
0030023406
-
Clinical studies of atovaquone alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand
-
Looareesuwan, S., Viravan, C., Webster, H.K., Kyle, D.E., Hutchinson, D.B., Canfield, C.J., 1996. Clinical studies of atovaquone alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. Am. J. Trop. Med. Hyg. 54, 62-66.
-
(1996)
Am. J. Trop. Med. Hyg.
, vol.54
, pp. 62-66
-
-
Looareesuwan, S.1
Viravan, C.2
Webster, H.K.3
Kyle, D.E.4
Hutchinson, D.B.5
Canfield, C.J.6
-
22
-
-
0015988739
-
Dihydropteroate synthetase from Plasmodium berghei: Isolation, properties and inhibition by dapsone and sulfadiazine
-
McCulloch, J.L., Maren, T.H., 1974. Dihydropteroate synthetase from Plasmodium berghei: isolation, properties and inhibition by dapsone and sulfadiazine. Mol. Pharmacol. 10, 140-145.
-
(1974)
Mol. Pharmacol.
, vol.10
, pp. 140-145
-
-
McCulloch, J.L.1
Maren, T.H.2
-
23
-
-
0028342547
-
Proguanil plus sulfamethoxazole is not causally prophylactic in the macaca mulatta-Plasmodium cynomolgi model
-
Shanks, G.D., Edstein, M.D., Chedester, L.A., Smith, C.D., Corcoran, K.D., Ngampochjana, M., Hansukjariya, P., Sattabongkot, J., Webster, H.K., 1994. Proguanil plus sulfamethoxazole is not causally prophylactic in the macaca mulatta-Plasmodium cynomolgi model. Am. J. Trop. Med. Hyg. 50, 641-645.
-
(1994)
Am. J. Trop. Med. Hyg.
, vol.50
, pp. 641-645
-
-
Shanks, G.D.1
Edstein, M.D.2
Chedester, L.A.3
Smith, C.D.4
Corcoran, K.D.5
Ngampochjana, M.6
Hansukjariya, P.7
Sattabongkot, J.8
Webster, H.K.9
-
24
-
-
0028261219
-
Examination of some factors responsible for a food-induced increase in absorption of atovaquone
-
Rolan, P.E., Mercer, A.J., Weatherley, B.C., Holdich, T., Meire, H., Peck, R.W., Ridout, G., Posner, J., 1994. Examination of some factors responsible for a food-induced increase in absorption of atovaquone. Br. J. Clin. Pharmacol. 37, 13-20.
-
(1994)
Br. J. Clin. Pharmacol.
, vol.37
, pp. 13-20
-
-
Rolan, P.E.1
Mercer, A.J.2
Weatherley, B.C.3
Holdich, T.4
Meire, H.5
Peck, R.W.6
Ridout, G.7
Posner, J.8
-
25
-
-
0015212606
-
Dapsone induced agranulocytosis complicated by Gram negative septicaemia
-
Smithurst, B.A., Robertson, I., Naughton, M.A., 1971. Dapsone induced agranulocytosis complicated by Gram negative septicaemia. Med. J. Aust. 1, 537-539.
-
(1971)
Med. J. Aust.
, vol.1
, pp. 537-539
-
-
Smithurst, B.A.1
Robertson, I.2
Naughton, M.A.3
-
26
-
-
0019748202
-
Resistance of ten Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests
-
Thaithong, S., Beale, G.H., 1981. Resistance of ten Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests. Trans. Roy. Soc. Trop. Med. Hyg. 75, 271-273.
-
(1981)
Trans. Roy. Soc. Trop. Med. Hyg.
, vol.75
, pp. 271-273
-
-
Thaithong, S.1
Beale, G.H.2
-
27
-
-
0017311840
-
Human malaria parasites in continuous culture
-
Trager, W., Jensen, J.B., 1976. Human malaria parasites in continuous culture. Science 193, 673-675.
-
(1976)
Science
, vol.193
, pp. 673-675
-
-
Trager, W.1
Jensen, J.B.2
-
28
-
-
0023943586
-
Chlorproguanil/dapsone for the treatment of non-severe Plasmodium falciparum malaria in Kenya: A pilot study
-
Watkins, W.M., Brandling-Bennett, A.D., Nevill, C.G., Carter, J.Y., Boriga, D.A., Howells, R.E., Koech, D.K., 1988. Chlorproguanil/dapsone for the treatment of non-severe Plasmodium falciparum malaria in Kenya: a pilot study. Trans. Roy. Soc. Trop. Med. Hyg. 82, 398-403.
-
(1988)
Trans. Roy. Soc. Trop. Med. Hyg.
, vol.82
, pp. 398-403
-
-
Watkins, W.M.1
Brandling-Bennett, A.D.2
Nevill, C.G.3
Carter, J.Y.4
Boriga, D.A.5
Howells, R.E.6
Koech, D.K.7
-
29
-
-
0025080121
-
Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults
-
Watkins, W.M., Mberu, E.K., Nevill, C.G., Ward, S.A., Breckenridge, A.M., Koech, D.K., 1990. Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults. Trans. Roy. Soc. Trop. Med. Hyg. 84, 492-495.
-
(1990)
Trans. Roy. Soc. Trop. Med. Hyg.
, vol.84
, pp. 492-495
-
-
Watkins, W.M.1
Mberu, E.K.2
Nevill, C.G.3
Ward, S.A.4
Breckenridge, A.M.5
Koech, D.K.6
-
30
-
-
0023576724
-
Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects
-
Wattanagoon, Y., Taylor, R.B., Moody, R.R., Ochekpe, N.A., Looareesuwan, S., White, N.J., 1987. Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects. Br. J. Clin. Pharmacol. 24, 775-780.
-
(1987)
Br. J. Clin. Pharmacol.
, vol.24
, pp. 775-780
-
-
Wattanagoon, Y.1
Taylor, R.B.2
Moody, R.R.3
Ochekpe, N.A.4
Looareesuwan, S.5
White, N.J.6
-
31
-
-
0030969974
-
Effects of dual combinations of antifolates and atovaquone or dapsone on nucleotide levels in Plasmodium falciparum
-
in press
-
Yeo, A.E.T., Seymour, K.K., Rieckmann, K.H. and Christopherson, R.I., 1997. Effects of dual combinations of antifolates and atovaquone or dapsone on nucleotide levels in Plasmodium falciparum. Biochem. Pharmacol. (in press).
-
(1997)
Biochem. Pharmacol.
-
-
Yeo, A.E.T.1
Seymour, K.K.2
Rieckmann, K.H.3
Christopherson, R.I.4
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