Studies on the relationships between 7α-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase

Biochimica et Biophysica Acta - Lipids and Lipid Metabolism

Volumn 1344, Issue 3, 1997, Pages 241-249

  Zhang, Jie ^a   Dricu, Anica ^a   Sjövall, Jan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

25 Hydroxycholesterol; 27 Hydroxycholesterol; 7 Hydroxylation; Dehydroepiandrosterone; HMG CoA reductase; Human fibroblast; Pregnenolone; Tumor cell; Virus transformed fibroblast

Indexed keywords

25 HYDROXYCHOLESTEROL; 26 HYDROXYCHOLESTEROL; 7ALPHA,25 DIHYDROXYCHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; DEXAMETHASONE; HYDROCORTISONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; METYRAPONE; PRASTERONE; PREGNENOLONE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CELL LINE; CHOLESTEROL METABOLISM; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; HYDROXYLATION; MELANOMA CELL; PRIORITY JOURNAL; TUMOR CELL; VIRUS CELL TRANSFORMATION;

ARYL HYDROCARBON HYDROXYLASES; CELL LINE; CELL LINE, TRANSFORMED; CHOLESTENONES; CYTOCHROME P-450 ENZYME SYSTEM; DEHYDROEPIANDROSTERONE; DEXAMETHASONE; HUMANS; HYDROCORTISONE; HYDROXYCHOLESTEROLS; HYDROXYLATION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; METYRAPONE; PREGNENOLONE; STEROID HYDROXYLASES; TUMOR CELLS, CULTURED;

EID: 0031576838     PISSN: 00052760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2760(96)00148-8     Document Type: Article

References (45)

1. Smith, L.L. and Johnson, B.H. (1989) Free Radic. Biol. Med. 7, 285-332.
2. Andersson, S., Davis, D.L., Dahlbäck, H., Jörnvall, H. and Russell, D.W. (1989) J. Biol. Chem. 264, 8222-8229.
3. Skrede, S., Björkhem, I., Kvittingen, E.A., Buchmann, M.S., Lie, S.O., East, C. and Grundy, S. (1986) J. Clin. Invest. 78, 729-735.
4. Pedersen, J.I., Oftebro, H. and Björkhem, I. (1989) Biochem. Int. 18, 615-622.
5. Cali, J.I. and Russell, D.W. (1991) J. Biol. Chem. 266, 7774-7778.
6. Axelson, M., Shoda, J., Sjövall, J., Toll, A. and Wikvall, K. (1992) J. Biol. Chem. 267, 1701-1704.
7. Toll, A., Shoda, J., Axlson, M., Sjövall, J. and Wikvall, K. (1992) FEBS Lett. 296, 73-76.
8. Shoda, J., Toll, A., Axelson, M., Pieper, F., Wikvall, K. and Sjövall, J. (1993) Hepatology 17, 395-403.
9. Björkhem, I., Nyberg, B. and Einarsson, K. (1992) Biochim. Biophys. Acta 1128, 73-76.
10. Martin, K.O., Budai, K. and Javitt, N.B. (1993) J. Lipid Res. 34, 581-588.
11. Zhang, J., Larsson, O. and Sjövall, J. (1995) Biochim. Biophys. Acta 1256, 353-359.
12. Zhang, J., Akwa, Y., Baulieu, E.E. and Sjövall, J. (1995) C. R. Acad. Sci. Paris 318, 345-349.
13. Zhang, J., Akwa, Y., El-Etr, M., Baulieu, E.E. and Sjövall, J. (1996) Biochem. J. (in press).
14. Payne, D.W., Shackleton, C., Toms, H., Ben-Shlomo, I., Kol, S., deMoura, M., Strauss, J.F. and Adashi, E.Y. (1995) J. Biol. Chem. 270, 18888-18896.
15. Zhang, J., Xue, Y.T., Jondal, M. and Sjövall, J. (1996) Eur. J. Biochem. (submitted).
16. Lund, E., Andersson, O., Zhang, J., Babiker, A., Ahlborg, G., Diczfalusy, U., Einarsson, K., Sjövall, J. and Björkhem, I. (1996) Arterioscler. Thromb. Vasc. Biol. 16, 208-212.
17. Leighton, J.K., Dueland, S., Straka, M.S., Trawick, J. and Davis, R.A. (1991) Mol. Cell Biol. 11, 2049-2056.
18. Dueland, S., Trawick, J.D., Nenseter, M.S., MacPhee, A.A. and Davis, R.A. (1992) J. Biol. Chem. 267, 22695-22698.
19. Axelson, M., Sahlberg, B.L. and Sjövall, J. (1981) J. Chromatogr. Biomed. Appl. 224, 355-370.
20. Shoda, J., Axelson, M. and Sjövall, J. (1993) Steroids 58, 119-125.
21. Cavenee, W.K., Chen, H.W. and Kandutsch, A.A. (1981) J. Biol. Chem. 256, 2675-2681.
22. Ichimiya, H., Egestad, B., Nazer, H., Baginski, E.S., Clayton, P.T. and Sjövall, J. (1991) J. Lipid Res. 32, 829-841.
23. Tint, C.S. Dayal, B., Batta, A.K., Shefer, S., Cheng, F.W., Salen, C.G. and Mosbach, E.H. (1978) J. Lipid Res. 19, 956-966.
24. Breuer, O. (1995) J. Lipid Res. 36, 2275-2281.
25. Akwa, Y., Morfin, R.F., Robel, P. and Baulieu, E.E. (1992) Biochem. J. 288, 959-964.
26. Johansson, G. (1971) Eur. J. Biochem. 21, 68-69.
27. Khalil, M.W., Strutt, B., Vachon, D. and Killinger, D.W. (1993) J. Steroid Biochem. Mol. Biol. 46, 585-595.
28. Kandutsch, A.A. and Chen, H.W. (1973) J. Biol. Chem. 248, 8408-8417.
29. Kandutsch, A.A., Heiniger, H.J. and Chen, H.W. (1977) Biochim. Biophys. Acta 486, 260-272.
30. Axelson, M., Larsson, O., Zhang, J., Shoda, J. and Sjövall, J. (1995) J. Lipid Res. 36, 290-298.
31. Kandutsch, A.A., Chen, H.W. and Shown, E.P. (1977) Proc. Natl. Acad. Sci. USA 74, 2500-2503.
32. Kandutsch, A.A. and Thompson, E.B. (1980) J. Biol. Chem. 255, 10813-10821.
33. Ridgway, N.D., Dawson, P.A., Ho, Y.K., Brown, M.S. and Goldstein, J.L. (1992) J. Cell Biol. 116, 307-319.
34. Larsson, O., Barrious, C., Latham, C., Ruiz, J., Zetterberg, A., Zickert, P. and Weide, J. (1989) Cancer Res. 49, 5605-5610.
35. Axelson, M. and Larsson, O. (1996) J. Biol. Chem. 271, 12724-12736.
36. Lund, E. and Björkhem, I. (1994) Biochemistry 33, 291-297.
37. Saucier, S.E., Kandutsch, A.A., Gayen, A.K., Swahn, D.K. and Spencer, T.A. (1989) J. Biol. Chem. 264, 6863-6869.
38. Caprio, J.D., Yun, J. and Javitt, N.B. (1992) J. Lipid Res. 33, 441-443.
39. Stravitz, R.T., Vlahcevic, Z.R., Russell, T.L., Heizer, M.L., Avadhani, N.G. and Hylemon, P.B. (1996) J. Steroid Biochem. Mol. Biol. 57, 337-347.
40. Petrack, B. and Latario, B.J. (1993) J. Lipid Res. 34, 643-649.
41. Wang, X., Sato, R., Brown, M.S., Hua, X. and Goldstein, J.L. (1994) Cell 77, 53-62.
42. Sheng, Z., Otani, H., Brown, M.S. and Goldstein, J.L. (1995). Proc. Natl. Acad. Sci. USA 92, 935-938.
43. Goldstein, J.L. and Brown, M.S. (1990) Nature 343, 425-430.
44. Pascale, R.M., Simile, M.M., De Miglio, M.R., Nufris, A., Seddaiu, M.A., Muroni, M.R., Danni, O., Rao, K.N. and Feo, F. (1995) Carcinogenesis 16, 1537-1542.
45. Erickson, K.A. and Nes, W.R. (1982) Proc. Natl. Acad. Sci. USA 79, 4873-4877.