메뉴 건너뛰기




Volumn 227, Issue 1, 1997, Pages 160-167

Assemblin homolog of herpes simplex virus type 1 retains proteolytic activity when expressed as a recombinant two-chain enzyme

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; RECOMBINANT PROTEIN;

EID: 0031555631     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.8335     Document Type: Article
Times cited : (3)

References (34)
  • 1
    • 0027402613 scopus 로고
    • Expression and analysis of the human cytomegalovirus UL80-encoded protease: Identification of autoproteolytic sites
    • Baum, E. Z., Bebernitz, G. A., Hulmes, J. D., Muzithras, V. P., Jones, T. R., and Gluzman, Y. (1993). Expression and analysis of the human cytomegalovirus UL80-encoded protease: Identification of autoproteolytic sites. J. Virol. 67(1), 497-506.
    • (1993) J. Virol. , vol.67 , Issue.1 , pp. 497-506
    • Baum, E.Z.1    Bebernitz, G.A.2    Hulmes, J.D.3    Muzithras, V.P.4    Jones, T.R.5    Gluzman, Y.6
  • 2
    • 0024389477 scopus 로고
    • Comparitive analysis of viral cysteine protease structural models
    • Bazan, J. F., and Fletterick, R. J. (1989). Comparitive analysis of viral cysteine protease structural models. FEBS Lett. 249(1), 5-7.
    • (1989) FEBS Lett. , vol.249 , Issue.1 , pp. 5-7
    • Bazan, J.F.1    Fletterick, R.J.2
  • 3
    • 0028300385 scopus 로고
    • Human cytomegalovirus proteinase: Purification of the enzyme and determination of its activity using peptide substrates that mimic its native cleavage sites
    • Burck, P. J., Berg, D. H., Luk, T. P., Sassmannshausen, L. M., Wakulchik, M., Becker, G. W., Smith, D. P., Hsiung, H. M., Gibson, W., and Villarreal, E. C. (1994). Human cytomegalovirus proteinase: Purification of the enzyme and determination of its activity using peptide substrates that mimic its native cleavage sites. J. Virol. 68(5), 2937-2946.
    • (1994) J. Virol. , vol.68 , Issue.5 , pp. 2937-2946
    • Burck, P.J.1    Berg, D.H.2    Luk, T.P.3    Sassmannshausen, L.M.4    Wakulchik, M.5    Becker, G.W.6    Smith, D.P.7    Hsiung, H.M.8    Gibson, W.9    Villarreal, E.C.10
  • 4
    • 0028130905 scopus 로고
    • Enhancement of Baculovirus plaque assay in insect cell monolayers by DEAE-dextran
    • Carrascosa, A. L. (1994). Enhancement of Baculovirus plaque assay in insect cell monolayers by DEAE-dextran. Biotechniques 16(6), 1078-1081, 1083-1085.
    • (1994) Biotechniques , vol.16 , Issue.6 , pp. 1078-1081
    • Carrascosa, A.L.1
  • 5
    • 0029018341 scopus 로고
    • Human cytomegalovirus proteinase: Candidate glutamic acid identified as third member of putative active site triad
    • Cox, G. A., Wakulchik, M., Sassmannshausen, L. M., Gibson, W., and Villarreal, E. C. (1995). Human cytomegalovirus proteinase: Candidate glutamic acid identified as third member of putative active site triad. J. Virol. 69(7), 4524-4528.
    • (1995) J. Virol. , vol.69 , Issue.7 , pp. 4524-4528
    • Cox, G.A.1    Wakulchik, M.2    Sassmannshausen, L.M.3    Gibson, W.4    Villarreal, E.C.5
  • 6
    • 0026666691 scopus 로고
    • Identification of genes encoding two capsid proteins (VP24 and VP26) of herpes simplex virus type 1
    • Davison, M. D., Rixon, F. J., and Davison, A. J. (1992). Identification of genes encoding two capsid proteins (VP24 and VP26) of herpes simplex virus type 1. J. Gen. Virol. 73, 2709-2713.
    • (1992) J. Gen. Virol. , vol.73 , pp. 2709-2713
    • Davison, M.D.1    Rixon, F.J.2    Davison, A.J.3
  • 7
    • 0027510939 scopus 로고
    • Identification of the herpes simplex virus type 1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products
    • Dilanni, C. L., Drier, D. A., Deckman, I. C., McCann, P. J., Liu, F., Roizman, B., Colonno, R. J., and Cordingley, M. G. (1993). Identification of the herpes simplex virus type 1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products. J. Biol. Chem. 268(3), 2048-2051.
    • (1993) J. Biol. Chem. , vol.268 , Issue.3 , pp. 2048-2051
    • Dilanni, C.L.1    Drier, D.A.2    Deckman, I.C.3    McCann, P.J.4    Liu, F.5    Roizman, B.6    Colonno, R.J.7    Cordingley, M.G.8
  • 8
    • 0028318401 scopus 로고
    • Identification of the serine residue at the active site of the herpes simplex virus type I protease
    • Dilanni, C. L., Stevens, J. T., Bolgar, M., O'Boyle, D. R., Weinheimer, S. P., and Colonno, R. J. (1994). Identification of the serine residue at the active site of the herpes simplex virus type I protease. J. Biol. Chem. 269(17), 12672-12676.
    • (1994) J. Biol. Chem. , vol.269 , Issue.17 , pp. 12672-12676
    • Dilanni, C.L.1    Stevens, J.T.2    Bolgar, M.3    O'Boyle, D.R.4    Weinheimer, S.P.5    Colonno, R.J.6
  • 9
    • 0028890518 scopus 로고
    • Characterization of the Epstein-Barr virus proteinase and comparison with the human cytomegalovirus proteinase
    • Donaghy, G., and Jupp, R. (1995). Characterization of the Epstein-Barr virus proteinase and comparison with the human cytomegalovirus proteinase. J. Virol. 69(2), 1265-1270.
    • (1995) J. Virol. , vol.69 , Issue.2 , pp. 1265-1270
    • Donaghy, G.1    Jupp, R.2
  • 10
    • 0019494532 scopus 로고
    • Structural and nonstructural proteins of strain Colburn cytomegalovirus
    • Gibson, W. (1981). Structural and nonstructural proteins of strain Colburn cytomegalovirus. Virol. 111, 516-537.
    • (1981) Virol. , vol.111 , pp. 516-537
    • Gibson, W.1
  • 11
    • 0000058254 scopus 로고
    • Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals
    • Gibson, W., Welch, A. R., and Hall, M. R. T. (1995). Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals. Persp. Drug Discovery Design 2, 413-426.
    • (1995) Persp. Drug Discovery Design , vol.2 , pp. 413-426
    • Gibson, W.1    Welch, A.R.2    Hall, M.R.T.3
  • 12
    • 0028673278 scopus 로고
    • Transient transfection assay of the herpesvirus maturational proteinase, assemblin
    • Gibson, W., Welch, A. R., and Ludford, J. (1994). Transient transfection assay of the herpesvirus maturational proteinase, assemblin. Methods Enzymol. 244, 399-411.
    • (1994) Methods Enzymol. , vol.244 , pp. 399-411
    • Gibson, W.1    Welch, A.R.2    Ludford, J.3
  • 13
    • 0029943395 scopus 로고    scopus 로고
    • Cytomegalovirus assemblin: The amino and carboxyl domains of the proteinase form active enzyme when separately cloned and co-expressed in eukaryotic cells
    • Hall, M. R. T., and Gibson, W. (1996). Cytomegalovirus assemblin: The amino and carboxyl domains of the proteinase form active enzyme when separately cloned and co-expressed in eukaryotic cells. J. Virol. 70(8), 5395-5404.
    • (1996) J. Virol. , vol.70 , Issue.8 , pp. 5395-5404
    • Hall, M.R.T.1    Gibson, W.2
  • 14
    • 0031031473 scopus 로고    scopus 로고
    • c,can restore proteolytic activity to assemblin mutants by intermolecular complementation
    • c,can restore proteolytic activity to assemblin mutants by intermolecular complementation. J. Virol. 71(2).
    • (1997) J. Virol. , vol.71 , Issue.2
    • Hall, M.R.T.1    Gibson, W.2
  • 16
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227, 680-685.
    • (1970) Nature (London) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 17
    • 0017670253 scopus 로고
    • 125I using intensifying screens and hypersensitized film
    • 125I using intensifying screens and hypersensitized film. FEBS Lett. 82, 314-316.
    • (1977) FEBS Lett. , vol.82 , pp. 314-316
    • Laskey, R.A.1    Mills, A.D.2
  • 18
    • 0026004785 scopus 로고
    • The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate
    • Liu, F., and Roizman, B. (1991). The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate. J. Virol. 65(10), 5149-5156.
    • (1991) J. Virol. , vol.65 , Issue.10 , pp. 5149-5156
    • Liu, F.1    Roizman, B.2
  • 19
    • 0028064282 scopus 로고
    • Cloning and sequence analysis of murine cytomegalovirus protease and capsid assembly protein genes
    • Loutsch, J. M., Galvin, N. J., Bryant, M. L., and Holwerda, B. C. (1994). Cloning and sequence analysis of murine cytomegalovirus protease and capsid assembly protein genes. Biochem. Biophys. Res. Commun. 203(1), 472-478.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , Issue.1 , pp. 472-478
    • Loutsch, J.M.1    Galvin, N.J.2    Bryant, M.L.3    Holwerda, B.C.4
  • 20
  • 21
    • 0028942788 scopus 로고
    • The effect of internal autocleavage on kinetic properties of the human cytomegalovirus protease catalytic domain
    • O'Boyle, D. R., Wager-Smith, K., Stevens, J. T., and Weinheimer, S. P. (1995). The effect of internal autocleavage on kinetic properties of the human cytomegalovirus protease catalytic domain. J. Biol. Chem. 270, 4753-4758.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4753-4758
    • O'Boyle, D.R.1    Wager-Smith, K.2    Stevens, J.T.3    Weinheimer, S.P.4
  • 23
    • 0027454011 scopus 로고
    • Herpes simplex virus type 1 capsid protein VP21 originates within the UL26 open reading frame
    • Person, S., Laquerre, S., Desai, P., and Hempel, J. (1993). Herpes simplex virus type 1 capsid protein VP21 originates within the UL26 open reading frame. J. Gen. Virol. 74, 2269-2273.
    • (1993) J. Gen. Virol. , vol.74 , pp. 2269-2273
    • Person, S.1    Laquerre, S.2    Desai, P.3    Hempel, J.4
  • 25
    • 0026516706 scopus 로고
    • Processing of the herpes simplex virus assembly protein ICP35 near its carboxy terminal end requires the product of the whole of the UL26 reading frame
    • Preston, V. G., Rixon, F. J., McDougall, I. M., McGregor, M., and Al Kobaisi, M. F. (1992). Processing of the herpes simplex virus assembly protein ICP35 near its carboxy terminal end requires the product of the whole of the UL26 reading frame. Virology 186, 87-98.
    • (1992) Virology , vol.186 , pp. 87-98
    • Preston, V.G.1    Rixon, F.J.2    McDougall, I.M.3    McGregor, M.4    Al Kobaisi, M.F.5
  • 26
    • 0014211618 scopus 로고
    • On the size of the active site in proteases. I. Papain
    • Schechter, I., and Berger, A. (1967). On the size of the active site in proteases. I. Papain. Biochem. Biophys. Res. Commun. 27, 157-162.
    • (1967) Biochem. Biophys. Res. Commun. , vol.27 , pp. 157-162
    • Schechter, I.1    Berger, A.2
  • 27
    • 0026081042 scopus 로고
    • The 45-kDa protein of cytomegalovirus (Colburn) B-capsids is an amino-terminal extension form of the assembly protein
    • Schenk, P., Woods, A. S., and Gibson, W. (1991). The 45-kDa protein of cytomegalovirus (Colburn) B-capsids is an amino-terminal extension form of the assembly protein. J. Virol. 65(3), 1525-1529.
    • (1991) J. Virol. , vol.65 , Issue.3 , pp. 1525-1529
    • Schenk, P.1    Woods, A.S.2    Gibson, W.3
  • 28
    • 0028109921 scopus 로고
    • In vitro proteolytic activity and active-site identification of the human cytomegalovirus proteinase
    • Stevens, J. T., Mapelli, C., Tsao, J., Hail, M., O'Boyle, D., Weinheimer, S. P., and Dilanni, C. L. (1994). In vitro proteolytic activity and active-site identification of the human cytomegalovirus proteinase. Eur. J. Biochem. 226(2), 361-367.
    • (1994) Eur. J. Biochem. , vol.226 , Issue.2 , pp. 361-367
    • Stevens, J.T.1    Mapelli, C.2    Tsao, J.3    Hail, M.4    O'Boyle, D.5    Weinheimer, S.P.6    Dilanni, C.L.7
  • 30
    • 0023101988 scopus 로고
    • Functional role of proteolytic cleavage at arginine-275 of human plasminogen activator as assessed by site-directed mutagenesis
    • Tate, K. M., Higgins, D. L., Holmes, W. E., Winkler, M. E., Heyneker, H. L., and Vehar, G. A. (1987). Functional role of proteolytic cleavage at arginine-275 of human plasminogen activator as assessed by site-directed mutagenesis. Biochemistry 26(2), 338-343.
    • (1987) Biochemistry , vol.26 , Issue.2 , pp. 338-343
    • Tate, K.M.1    Higgins, D.L.2    Holmes, W.E.3    Winkler, M.E.4    Heyneker, H.L.5    Vehar, G.A.6
  • 31
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T., and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 32
    • 0027428432 scopus 로고
    • Herpesvirus proteinase: Site-directed mutagenesis used to study maturational, release, and inactivation cleavage sites of precursor and to identify a possible catalytic site serine and histidine
    • Welch, A. R., McNally, L. M., Hall, M. R. T., and Gibson, W. (1993). Herpesvirus proteinase: Site-directed mutagenesis used to study maturational, release, and inactivation cleavage sites of precursor and to identify a possible catalytic site serine and histidine. J. Virol. 67(12), 7360-7372.
    • (1993) J. Virol. , vol.67 , Issue.12 , pp. 7360-7372
    • Welch, A.R.1    McNally, L.M.2    Hall, M.R.T.3    Gibson, W.4
  • 33
    • 0028908746 scopus 로고
    • Cytomegalovirus protein substrates are not cleaved by the herpes simplex type 1 proteinase
    • Welch, A. R., Villarreal, E. C., and Gibson, W. (1995). Cytomegalovirus protein substrates are not cleaved by the herpes simplex type 1 proteinase. J. Virol. 69(1), 341-347.
    • (1995) J. Virol. , vol.69 , Issue.1 , pp. 341-347
    • Welch, A.R.1    Villarreal, E.C.2    Gibson, W.3
  • 34
    • 0025721850 scopus 로고
    • A herpesvirus maturational protease, assemblin: Identification of its gene, putative active site domain, and cleavage site
    • Welch, A. R., Woods, A. S., McNally, L. M., Cotter, R. J., and Gibson, W. (1991). A herpesvirus maturational protease, assemblin: Identification of its gene, putative active site domain, and cleavage site. Proc. Natl. Acad. Sci. USA 88, 10792-10796.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10792-10796
    • Welch, A.R.1    Woods, A.S.2    McNally, L.M.3    Cotter, R.J.4    Gibson, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.