Inhibition of FGF-1 receptor tyrosine kinase activity by PD 161570, a new protein-tyrosine kinase inhibitor

Life Sciences

Volumn 62, Issue 2, 1997, Pages 143-150

  Batley, Brian L ^a   Doherty, Annette M ^a   Hamby, James M ^a   Lu, Gina H ^a   Keller, Paul ^a   Dahring, Tawny K ^a   Hwang, Ok ^a   Crickard, Kent ^b   Panek, Robert L ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Angiogenesis; FGF 1 receptor tyrosine kinase; PD 161570; Tyrosine phosphorylation

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR; PD 161570; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; OVARY CARCINOMA; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY;

EID: 0031555353     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)01060-6     Document Type: Article

References (35)

1. GLENNEY J.R. Biochem. Biophys. Acta. 1134:1992;113-127.
2. SCHLESSINGER J., ULLRICH A. Neuron. 9:1992;383-391.
3. PANAYOUTOU G., WATERFIELD M.D. Embo J. 20:1993;1347-1354.
4. DIONNE C.A., CRUMLEY G., BELLOT F. Embo J. 17:1990;2685-2692.
5. JAYE M., SCHLESSINGER J., DIONNE C.A. Biochem. Biophys. Acta. 1135:1992;185-199.
6. FRIESEL R.E., MACIAG T. FASEB J. 9:1995;919-925.
7. BURGESS W.H., MACIAG T. Annu. Rev. Biochem. 58:1989;575-606.
8. MIYAMOTO M., NARUO K.-I., SEKO C., MATSUMOTO S., KONDO T., KUROKAWA T. Mol. Cell Biol. 13:1993;4251-4259.
9. LATHROP B., OLSON E., GLASSER L. J. Cell Biol. 100:1985;8232-8239.
10. TOGARI A., DICKENS G., KUZUYA H. J. Neurosci. 5:1985;307-316.
11. KIMELMAN D., ABRAHAM J.A., HAAPARANTA T. Science. 242:1988;1053-1056.
12. SCHOTT R.J., MORROW L.A. Cardiovasc. Res. 27:1993;1155-1161.
13. FOLKMAN J. J. Clin. Oncol. 12:1994;441-443.
14. CANTLEY L.C., AUGER K.R., CARPENTER C. Cell. 64:1991;281-302.
15. CADENA D.L., GILL G.N. FASEB J. 6:1992;2332-2337.
16. HOU J.Z., MCKEEHAN W., KAN M.K. Pro. Sci. 2:1993;86-92.
17. MOHAMMADI M., HONEGGER A.M., ROTIN D., FISCHER R., BELLOT F., LI W., DIONNE C.A., JAYE M., RUBINSTEIN M., SCHLESSINGER J. Mol. Cell. Biol. 11:1991;5068-5078.
18. ZHAN X., PLOURDE C., HU X., FRIESEL R., MACIAG T. J. Biol. Chem. 269:1994;20221-20224.
19. FOLKMAN J., KLAGSBRUN M. Science. 235:1987;442-447.
20. KLAGSBRUN M., EDELMAN E.R. Arteriosclerosis. 9:1989;269-278.
21. VASSAR R., FUCHS E. Gene and Dev. 5:1991;714-727.
22. ROSS R. Lancet. 1:1989;1179-1182.
23. LIBBY P., SCHWARTZ D., BROGI E. Circulation. 86:1992;47-52.
24. NABEL E.G., YANG Z.-Y., PLAUTZ G., FOROUGH R., ZHAN X., HAUDENSCHILD C.C., MACIAG T., NABEL G.J. Nature. 362:1993;844-846.
25. AKIYAMA T., ISHIDA J., NAKAGAWA S., OGAWARA H., WATANABE S., ITOH N., SHIBUYUA M., FUKAMI Y. J. Biol. Chem. 262:1987;5592-5595.
26. BILDER G.E., KRAWIEC J.A., MCVETY K., GAZIT A., GILON C., LYALL R., ZILBERSTEIN A., LEVITZKI A., PERRONE M.H., SCHREIBER A.B. Am. J. Physiol. 260:1991;C721-C730.
27. LYALL R.M., ZILBERSTEIN A., GAZIT A., GILON C., LEVITZKI A., SCHLESSINGER J. J. Biol. Chem. 264:1989;14503-14509.
28. UMEZAWA K., IMOTO M. Methods Enzymol. 201:1991;379-385.
29. MOHAMMADI M., McMAHON G., SUN L., TANG C., HIRTH P., YEH B.K., HUBBARD S.R., SCHLESSINGER J. Science. 276:1997;955-960.
30. FRY D.W., KRAKER A.J., MCMICHAEL A., AMBROSO L.A., NELSON J.M., LEOPOLD W.R., CONNORS R.W., BRIDGES A.J. Science. 265:1994;1093-1095.
31. BUCHDUNGER E., ZIMMERMAN J., METT H., MEYER T., MULLER M., REGENASS U., LYDON N.B. Proc. Natl. Acad. Sci. U.S.A. 92:1995;2558-2562.
32. CRICKARD K., GROSS J.L., CRICKARD U., YOONESSI M., LELE S., HERBLIN W.F., EIDSVOOG K. Gynecol. Oncol. 55:1994;277-284.
33. DAHRING T.K., LU G.H., HAMBY J.M., BATLEY B.L., KRAKER A.J., PANEK R.L. J. Pharmacol. Exp. Ther. 281:1997;1446-1456.
34. CLELAND W.W. Methods in Enzymol. 63:1979;103-112.
35. R.J. LEATHERBARROW. GraFit User's Guide, Version 3.0. Erithacus Software Ltd., Staines, U.K. (1992).