An invariant lysine residue is involved in catalysis at the 3'-5' exonuclease active site of eukaryotic-type DNA polymerases

Journal of Molecular Biology

Volumn 270, Issue 1, 1997, Pages 65-78

  De Vega, Miguel ^a   Ilyina, Tatjana ^a,b   Lázaro, José M ^a   Salas, Margarita ^a   Blanco, Luis ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

3' 5' exonuclease; Site directed mutagenesis; 29 dna polymerase

Indexed keywords

ARGININE; DNA POLYMERASE; EXONUCLEASE; ISOLEUCINE; LYSINE; SINGLE STRANDED DNA;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTALLOGRAPHY; DNA SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; NONHUMAN; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SITE DIRECTED MUTAGENESIS;

EUKARYOTA;

EID: 0031552594     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1093     Document Type: Article

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