-
1
-
-
0021891887
-
Effects of site-specific amino acid modification on protein interactions and biological function
-
Ackers G. K., Smith F. R. Effects of site-specific amino acid modification on protein interactions and biological function. Annu. Rev. Biochem. 54:1985;597-629.
-
(1985)
Annu. Rev. Biochem.
, vol.54
, pp. 597-629
-
-
Ackers, G.K.1
Smith, F.R.2
-
2
-
-
0028287089
-
Subsite binding in an RNase: Structure of a barnase-tetranucleotide complex at 1.76 Å resolution
-
Buckle A. M., Fersht A. R. Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76 Å resolution. Biochemistry. 33:1994;1644-1653.
-
(1994)
Biochemistry
, vol.33
, pp. 1644-1653
-
-
Buckle, A.M.1
Fersht, A.R.2
-
3
-
-
0028074974
-
Protein-protein recognition: Crystal structural analysis of a barnase-barstar complex at 2.0-Å resolution
-
Buckle M., Schreiber G., Fersht A. R. Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-Å resolution. Biochemistry. 33:1994;8878-8889.
-
(1994)
Biochemistry
, vol.33
, pp. 8878-8889
-
-
Buckle, M.1
Schreiber, G.2
Fersht, A.R.3
-
4
-
-
0022450133
-
Amino-aromatic interactions in proteins
-
Burley S. K., Petsko G. A. Amino-aromatic interactions in proteins. FEBS Letters. 203:1986;139-143.
-
(1986)
FEBS Letters
, vol.203
, pp. 139-143
-
-
Burley, S.K.1
Petsko, G.A.2
-
5
-
-
0026044754
-
Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy
-
Bycroft M., Ludvingen S., Fersht A. R., Poulsen F. M. Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy. Biochemistry. 30:1991;8697-8701.
-
(1991)
Biochemistry
, vol.30
, pp. 8697-8701
-
-
Bycroft, M.1
Ludvingen, S.2
Fersht, A.R.3
Poulsen, F.M.4
-
6
-
-
0021504608
-
The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)
-
Carter P. J., Winter G., Wilkinson A. J., Fersht A. R. The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus). Cell. 38:1984;835-840.
-
(1984)
Cell
, vol.38
, pp. 835-840
-
-
Carter, P.J.1
Winter, G.2
Wilkinson, A.J.3
Fersht, A.R.4
-
7
-
-
0027155577
-
Engineered disulfide bonds as probes of the folding pathway of barnase: Increasing the stability of proteins against the rate of denaturation
-
Clarke J., Fersht A. R. Engineered disulfide bonds as probes of the folding pathway of barnase: increasing the stability of proteins against the rate of denaturation. Biochemistry. 32:1993;4322-4329.
-
(1993)
Biochemistry
, vol.32
, pp. 4322-4329
-
-
Clarke, J.1
Fersht, A.R.2
-
9
-
-
0027132013
-
Comparison of a structural and a functional epitope
-
Cunningham B. C., Wells J. A. Comparison of a structural and a functional epitope. J. Mol. Biol. 234:1993;554-563.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 554-563
-
-
Cunningham, B.C.1
Wells, J.A.2
-
10
-
-
0026751045
-
Barnase has subsites that give rise to large rate enhancements
-
Day A. G., Parsonage D., Ebel S., Brown T., Fersht A. R. Barnase has subsites that give rise to large rate enhancements. Biochemistry. 31:1992;6390-6395.
-
(1992)
Biochemistry
, vol.31
, pp. 6390-6395
-
-
Day, A.G.1
Parsonage, D.2
Ebel, S.3
Brown, T.4
Fersht, A.R.5
-
11
-
-
0029997591
-
On the choice of reference mutant states in the application of the double-mutant cycle method
-
Faiman G. A., Horovitz A. On the choice of reference mutant states in the application of the double-mutant cycle method. Protein Eng. 9:1996;315-316.
-
(1996)
Protein Eng.
, vol.9
, pp. 315-316
-
-
Faiman, G.A.1
Horovitz, A.2
-
12
-
-
0026511656
-
The folding of an enzyme I: Theory of protein engineering analysis of stability and pathway of protein folding
-
Fersht A. R., Matouschek A., Serrano L. The folding of an enzyme I: Theory of protein engineering analysis of stability and pathway of protein folding. J. Mol. Biol. 224:1992;771-782.
-
(1992)
J. Mol. Biol.
, vol.224
, pp. 771-782
-
-
Fersht, A.R.1
Matouschek, A.2
Serrano, L.3
-
13
-
-
0031552366
-
Thermodynamics of the interaction of barnase and barstar: Changes in free energy versus changes in enthalpy on mutation
-
Frisch C., Schreiber G., Johnson C. M., Fersht A. R. Thermodynamics of the interaction of barnase and barstar: changes in free energy versus changes in enthalpy on mutation. J. Mol. Biol. 267:1997;696-706.
-
(1997)
J. Mol. Biol.
, vol.267
, pp. 696-706
-
-
Frisch, C.1
Schreiber, G.2
Johnson, C.M.3
Fersht, A.R.4
-
14
-
-
0024448151
-
Calculation of protein extinction coefficients from amino acid sequence data
-
Gill S. C., von Hippel P. H. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182:1989;319-326.
-
(1989)
Anal. Biochem.
, vol.182
, pp. 319-326
-
-
Gill, S.C.1
Von Hippel, P.H.2
-
15
-
-
0027132431
-
Recognition between a bacterial ribonuclease, barnase and its natural inhibitor, barstar
-
Guillet V., Lapthorn A., Hartley R. W., Maugen Y. Recognition between a bacterial ribonuclease, barnase and its natural inhibitor, barstar. Structure. 1:1993;165-177.
-
(1993)
Structure
, vol.1
, pp. 165-177
-
-
Guillet, V.1
Lapthorn, A.2
Hartley, R.W.3
Maugen, Y.4
-
16
-
-
0024453699
-
Barnase and barstar: Two small proteins to fold and fit together
-
Hartley R. W. Barnase and barstar: two small proteins to fold and fit together. Trends Biochem. Sci. 14:1989;450-454.
-
(1989)
Trends Biochem. Sci.
, vol.14
, pp. 450-454
-
-
Hartley, R.W.1
-
17
-
-
0027318108
-
Directed mutagenesis and barnase-barstar recognition
-
Hartley R. W. Directed mutagenesis and barnase-barstar recognition. Biochemistry. 32:1993;5978-5984.
-
(1993)
Biochemistry
, vol.32
, pp. 5978-5984
-
-
Hartley, R.W.1
-
18
-
-
0001629142
-
The structural and sequence homology of a family of microbial ribonucleases
-
Hill C., Dodson G., Heinemann U., Saenger W., Mitsui Y., Nakamura K., Borisov S., Tischenko G., Polyakov K., Pavlovsky S. The structural and sequence homology of a family of microbial ribonucleases. Trends. Biochem. Sci. 8:1983;364-369.
-
(1983)
Trends. Biochem. Sci.
, vol.8
, pp. 364-369
-
-
Hill, C.1
Dodson, G.2
Heinemann, U.3
Saenger, W.4
Mitsui, Y.5
Nakamura, K.6
Borisov, S.7
Tischenko, G.8
Polyakov, K.9
Pavlovsky, S.10
-
19
-
-
0023645205
-
Non-additivity in protein-protein interactions
-
Horovitz A. Non-additivity in protein-protein interactions. J. Mol. Biol. 196:1987;733-735.
-
(1987)
J. Mol. Biol.
, vol.196
, pp. 733-735
-
-
Horovitz, A.1
-
20
-
-
0025663105
-
Strength and cooperativity of contributions of surface salt bridges to protein stability
-
Horovitz A., Serrano L., Avron B., Bycroft M., Fersht A. R. Strength and cooperativity of contributions of surface salt bridges to protein stability. J. Mol. Biol. 216:1990;1031-1044.
-
(1990)
J. Mol. Biol.
, vol.216
, pp. 1031-1044
-
-
Horovitz, A.1
Serrano, L.2
Avron, B.3
Bycroft, M.4
Fersht, A.R.5
-
21
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones T. A., Zou J. Y., Cowan S. W., Kjelgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallog. sect. A. 47:1991;110-119.
-
(1991)
Acta Crystallog. Sect. A
, vol.47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjelgaard, M.4
-
22
-
-
0027966019
-
13C assignments and three-dimensional solution structure of barstar using nuclear magnetic resonance spectroscopy
-
13C assignments and three-dimensional solution structure of barstar using nuclear magnetic resonance spectroscopy. Biochemistry. 33:1994;8866-8877.
-
(1994)
Biochemistry
, vol.33
, pp. 8866-8877
-
-
Lubienski, M.J.1
Bycroft, M.2
Freund, S.M.V.3
Fersht, A.R.4
-
23
-
-
0019944172
-
Molecular structure of a new family of ribonucleases
-
Mauguen Y., Hartley R. W., Dodson E. J., Dodson G. G., Bricogne G., Chothia C., Jack A. Molecular structure of a new family of ribonucleases. Nature. 29:1982;162-164.
-
(1982)
Nature
, vol.29
, pp. 162-164
-
-
Mauguen, Y.1
Hartley, R.W.2
Dodson, E.J.3
Dodson, G.G.4
Bricogne, G.5
Chothia, C.6
Jack, A.7
-
24
-
-
0026723477
-
Effect of active site residues in barnase on activity and stability
-
Meiering E. M., Serrano L., Fersht A. R. Effect of active site residues in barnase on activity and stability. J. Mol. Biol. 225:1992;585-589.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 585-589
-
-
Meiering, E.M.1
Serrano, L.2
Fersht, A.R.3
-
25
-
-
0027520474
-
Structure and dynamics of barnase complexed with 3′-GMP studied by NMR spectroscopy
-
Meiering E. M., Bycroft M., Lubienski M. J., Fersht A. R. Structure and dynamics of barnase complexed with 3′-GMP studied by NMR spectroscopy. Biochemistry. 32:1993;10975-10986.
-
(1993)
Biochemistry
, vol.32
, pp. 10975-10986
-
-
Meiering, E.M.1
Bycroft, M.2
Lubienski, M.J.3
Fersht, A.R.4
-
26
-
-
0024501923
-
Kinetic characterization of the recombinant ribonuclease from Bacillus amyloliquefaciens (barnase) and investigation of key residues in catalysis by site-directed mutagenesis
-
Mossakowska D. E., Nyberg K., Fersht A. R. Kinetic characterization of the recombinant ribonuclease from Bacillus amyloliquefaciens (barnase) and investigation of key residues in catalysis by site-directed mutagenesis. Biochemistry. 28:1989;3843-3850.
-
(1989)
Biochemistry
, vol.28
, pp. 3843-3850
-
-
Mossakowska, D.E.1
Nyberg, K.2
Fersht, A.R.3
-
27
-
-
0023667708
-
1activity as is the case for ribonuclease A
-
1activity as is the case for ribonuclease A. Biochemistry. 26:1987;8620-8624.
-
(1987)
Biochemistry
, vol.26
, pp. 8620-8624
-
-
Nishikawa, S.1
Morioka, H.2
Kim, H.J.3
Fuchimura, K.4
Tanaka, T.5
Uesugi, S.6
Hakoshima, T.7
Tomita, K.8
Ohtsuka, E.9
Ikehara, M.10
-
28
-
-
0001274586
-
Studies on B. subtilis ribonuclease. I. Characterization of enzymatic specificity
-
Rushizky G. W., Greco A. E., Hartley R. W., Sober H. A. Studies on B. subtilis ribonuclease. I. Characterization of enzymatic specificity. Biochemistry. 2:1963;787-793.
-
(1963)
Biochemistry
, vol.2
, pp. 787-793
-
-
Rushizky, G.W.1
Greco, A.E.2
Hartley, R.W.3
Sober, H.A.4
-
29
-
-
0024284014
-
5′-3′ exonucleases in phosphorothioate-based oligonucleotide directed mutagenesis
-
Sayers J. R., Schmidt W., Eckstein F. 5′-3′ exonucleases in phosphorothioate-based oligonucleotide directed mutagenesis. Nucl. Acids Res. 16:1988;791-802.
-
(1988)
Nucl. Acids Res.
, vol.16
, pp. 791-802
-
-
Sayers, J.R.1
Schmidt, W.2
Eckstein, F.3
-
30
-
-
0027177102
-
The interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering
-
Schreiber G., Fersht A. R. The interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering. Biochemistry. 32:1993a;5145-5150.
-
(1993)
Biochemistry
, vol.32
, pp. 5145-5150
-
-
Schreiber, G.1
Fersht, A.R.2
-
31
-
-
0027385015
-
The refolding of cis - and trans - peptidylprolyl isomers of barstar
-
Schreiber G., Fersht A. R. The refolding of cis - and trans - peptidylprolyl isomers of barstar. Biochemistry. 32:1993b;11195-11203.
-
(1993)
Biochemistry
, vol.32
, pp. 11195-11203
-
-
Schreiber, G.1
Fersht, A.R.2
-
32
-
-
0029056922
-
Energetics of protein-protein interactions: Analysis of the barnase-barstar interface by single mutations and double mutant cycles
-
Schreiber G., Fersht A. R. Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles. J. Mol. Biol. 248:1995;478-486.
-
(1995)
J. Mol. Biol.
, vol.248
, pp. 478-486
-
-
Schreiber, G.1
Fersht, A.R.2
-
33
-
-
0029873697
-
Rapid, electrostatic assisted, association of proteins
-
Schreiber G., Fersht A. R. Rapid, electrostatic assisted, association of proteins. Nature Struc. Biol. 3:1996;427-431.
-
(1996)
Nature Struc. Biol.
, vol.3
, pp. 427-431
-
-
Schreiber, G.1
Fersht, A.R.2
-
34
-
-
0028774340
-
Stability versus function: Two competing forces in the evolution of barstar
-
Schreiber G., Buckle A. M., Fersht A. R. Stability versus function: two competing forces in the evolution of barstar. Structure. 2:1994;945-951.
-
(1994)
Structure
, vol.2
, pp. 945-951
-
-
Schreiber, G.1
Buckle, A.M.2
Fersht, A.R.3
-
35
-
-
0025093185
-
Estimating the contribution of engineered surface electrostatic interactions to protein stability using double-mutant cycles
-
Serrano L., Horovitz A., Avron B., Bycroft M., Fersht A. R. Estimating the contribution of engineered surface electrostatic interactions to protein stability using double-mutant cycles. Biochemistry. 29:1990;9343-9352.
-
(1990)
Biochemistry
, vol.29
, pp. 9343-9352
-
-
Serrano, L.1
Horovitz, A.2
Avron, B.3
Bycroft, M.4
Fersht, A.R.5
-
36
-
-
0025082684
-
Additivity of mutational effects in proteins
-
Wells J. A. Additivity of mutational effects in proteins. Biochemistry. 29:1990;8509-8517.
-
(1990)
Biochemistry
, vol.29
, pp. 8509-8517
-
-
Wells, J.A.1
-
37
-
-
0024356301
-
Rapid measurements of binding constants and heats of binding using a new titration calorimeter
-
Wiseman T., Williston S., Brandts J. F., Lin L. N. Rapid measurements of binding constants and heats of binding using a new titration calorimeter. Anal. Biochem. 179:1989;131-137.
-
(1989)
Anal. Biochem.
, vol.179
, pp. 131-137
-
-
Wiseman, T.1
Williston, S.2
Brandts, J.F.3
Lin, L.N.4
|