Thermodynamics of the interaction of barnase and barstar: Changes in free energy versus changes in enthalpy on mutation

Journal of Molecular Biology

Volumn 267, Issue 3, 1997, Pages 696-706

  Frisch, Christian ^a   Schreiber, Gideon ^a,b   Johnson, Christopher M ^a   Fersht, Alan R ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Heat capacity; Protein engineering; Protein protein interaction; Titration calorimetry

Indexed keywords

ENZYME INHIBITOR; GLUTAMIC ACID; RIBONUCLEASE;

AMINO ACID SUBSTITUTION; ARTICLE; CALORIMETRY; ENTHALPY; ENTROPY; GENETIC ENGINEERING; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

EID: 0031552366     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.0892     Document Type: Article

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