Glutamate and aspartate as proton shuttles in mutants of carbonic anhydrase

Biochemistry

Volumn 36, Issue 50, 1997, Pages 15758-15764

  Qian, Minzhang ^a   Tu, Chingkuang ^a   Earnhardt, J Nicole ^a   Laipis, Philip J ^a   Silverman, David N ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CARBON DIOXIDE; CARBONATE DEHYDRATASE; GLUTAMIC ACID; LEUCINE; LYSINE; MUTANT PROTEIN; OXYGEN 18; PHENYLALANINE; PROTON; ZINC;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; HUMAN; HYDRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT;

ANIMALS; ASPARTIC ACID; CARBON DIOXIDE; CARBONIC ANHYDRASES; GLUTAMIC ACID; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICE; MUTAGENESIS, SITE-DIRECTED; PROTONS; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; ZINC;

FELIS CATUS; MURINAE;

EID: 0031470780     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972081q     Document Type: Article

References (33)

1. Christianson, D. W., and Fierke, C. A. (1996) Acc. Chem. Res. 29, 331-339.
2. Silverman, D. N., and Lindskog S. (1988) Acc. Chem. Res. 21, 30-36.
3. Steiner, H., Jonsson, B.-H., and Lindskog, S. (1975) Eur. J. Biochem. 59, 253-259.
4. Tu, C. K., Silverman, D. N., Forsman, C., Jonsson, B. H., and Lindskog, S. (1989) Biochemistry 28, 7913-7918.
5. Eriksson, A. E., Jones, T. A., and Liljas, A. (1988) Proteins: Struct., Funct., Genet. 4, 274-282.
6. Scolnick, L. R., and Christianson, D. W. (1996) Biochemistry 35, 16429-16434.
7. Nagle, J. F., and Morowitz, H. J. (1978) Proc. Natl. Acad. Sci. U.S.A. 75, 298-302.
8. Pomés, R., and Roux, B. (1996) Biophys. J. 71, 19-39.
9. Pocker, Y., Janjic, N., and Miao, C. H. (1986) in Zinc Enzymes (Bertini, I., Luchinat, C., Maret, W., and Zeppezauer, M., Eds.) pp 341-356, Birkhauser, Boston.
10. Rowlett, R. S., and Silverman, D. N. (1982) J. Am. Chem. Soc. 104, 6737-6741.
11. Jewell, D. A., Tu, C. K., Paranawithana, S. R., Tanhauser, S. M., LoGrasso, P. V., Laipis, P. J., and Silverman, D. N. (1991)-Biochemistry 30, 1484-1490.
12. Heck, R. W., Boriack-Sjodin, P. A., Qian, M., Tu, C. K., Christianson, D. W., Laipis, P. J., and Silverman, D. N. (1996) Biochemistry 35, 11605-11611.
13. Boriak-Sjodin, P. A., Heck, R. W., Laipis, P. J., Silverman, D. N., and Christianson, D. W. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 10949-10953.
14. Eriksson, A. E., and Liljas, A. (1993) Proteins: Struct., Funct., Genet. 16, 29-42.
15. Dodgson, S. J. (1991) in The Carbonic Anhydrases (Dodgson, S. J., Tashian, R. E., Gros, G., and Carter, N. D., Eds.) pp 297-306, Plenum Press, New York.
16. Geers, C., and Gross, G. (1991) in The Carbonic Ahydrases (Dodgson, S. J., Tashian, R. E., Gros, G., and Carter, N. D., Eds.) pp 227-240, Plenum Press, New York.
17. Lynch, C. J., Brennen, W. A., Vary, T. C., Carter, N., and Dodgson, S. J. (1993) Am. J. Physiol. 264, E621-E630.
18. Heck, R. W., Tanhauser, S. M., Manda, R., Tu, C. K., Laipis, P. J., and Silverman, D. N. (1994) J. Biol. Chem. 269, 24742-24746.
19. Kunkel, T. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 488-492.
20. Tanhauser, S. M., Jewell, D. A., Tu, C. K., Silverman, D. N., and Laipis, P. J. (1992) Gene 117, 113-117.
21. Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Dubendorf, J. W. (1990) Methods Enzymol. 185, 60-89.
22. Khalifah, R. G., Strader, D. J., Bryant, S. H., and Gibson, S. M. (1977) Biochemistry 16, 2241-2247.
23. Segel, I. H. (1975) Enzyme Kinetics, pp 150-159, John Wiley & Sons, New York.
24. Tu, C. K., Thomas, H. G., Wynns, G. C., and Silverman, D. N. (1986) J. Biol. Chem. 261, 10100-10103.
25. Engberg, P., Millqvist, E., Pohl, G., and Lindskog, S. (1985) Arch. Biochem. Biophys. 241, 628-638.
26. Silverman, D. N. (1982) Methods Enzymol. 87, 732-752.
27. Simonsson, I., Jonsson, B.-H., and Lindskog, S. (1979) Eur. J. Biochem. 93, 409-417.
28. Silverman, D. N., Tu, C. K., Chen, X., Tanhauser, S. M., Kresge, A. J., and Laipis, P. J. (1993) Biochemistry 32, 10757-10762.
29. Khalifah, R. G. (1971) J. Biol. Chem. 246, 2561-2573.
30. LoGrasso, P. V., Tu, C. K., Jewell, D. A., Wynns, G. C., Laipis, P. J., and Silverman, D. N. (1991) Biochemistry 30, 8463-8470.
31. Forsman, C., Behravan, G., Jonsson, B.-H., Liang, Z.-W., Lindskog, S., Ren, X., Sandstrom, J., and Wallgren, K. (1988) FEBS Lett. 229, 360-362.
32. Engstrand, C., Forsman, C., Liang, Z., and Lindskog, S. (1992) Biochim. Biophys. Acta 1122, 321-326.
33. Jackman, J. E., Merz, K. M., and Fierke, C. A. (1996) Biochemistry 35, 16421-16428.