-
1
-
-
0029562631
-
Antiviral activity and protection of cells against human immunodeficiency virus type-1 using an antisense oligodeoxyribonucleotide phosphorothioate complementary to the 5'-LTR region of the viral genome
-
Anazodo M. I., Salomon H., Friesen A. D., Wainherg M. A. and Wright J. A. (1995) Antiviral activity and protection of cells against human immunodeficiency virus type-1 using an antisense oligodeoxyribonucleotide phosphorothioate complementary to the 5'-LTR region of the viral genome. Gene 166, 227-232.
-
(1995)
Gene
, vol.166
, pp. 227-232
-
-
Anazodo, M.I.1
Salomon, H.2
Friesen, A.D.3
Wainherg, M.A.4
Wright, J.A.5
-
3
-
-
0028176053
-
lys-3 as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/ template-switching reaction
-
lys-3 as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/ template-switching reaction. J. Biol. Chem. 269, 14672-14680.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14672-14680
-
-
Arts, E.J.1
Li, X.2
Gu, Z.3
Kleiman, L.4
Parniak, M.A.5
Wainberg, M.A.6
-
4
-
-
0027257467
-
RNase H activity of reverse transcriptases on substrates derived from the 5' end of retroviral genome
-
Ben-Artizi H., Zeelon E., Amit B., Wortzel A., Gorecki M. and Panet A. (1993) RNase H activity of reverse transcriptases on substrates derived from the 5' end of retroviral genome. J. Biol. Chem. 268, 16465-16471.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 16465-16471
-
-
Ben-Artizi, H.1
Zeelon, E.2
Amit, B.3
Wortzel, A.4
Gorecki, M.5
Panet, A.6
-
5
-
-
0029887654
-
A new antisense tRNA construct for the genetic treatment of human immunodeficiency virus type 1
-
Biasolo M. A., Radaelli A., Del Pup L., Franchin E., Giuli-Morghen C. and Palu G. (1996) A new antisense tRNA construct for the genetic treatment of human immunodeficiency virus type 1. J. Virol. 70, 2154-2161.
-
(1996)
J. Virol.
, vol.70
, pp. 2154-2161
-
-
Biasolo, M.A.1
Radaelli, A.2
Del Pup, L.3
Franchin, E.4
Giuli-Morghen, C.5
Palu, G.6
-
6
-
-
0026497713
-
In vitro effect of antisense oligonucleotides on human immunodeficiency virus type 1 reverse transcription
-
Bordier B., Helene C., Barr P. J., Litvak S. and Sarih-Cottin L. (1992) In vitro effect of antisense oligonucleotides on human immunodeficiency virus type 1 reverse transcription. Nucleic Acids Res. 20, 5999-6006.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5999-6006
-
-
Bordier, B.1
Helene, C.2
Barr, P.J.3
Litvak, S.4
Sarih-Cottin, L.5
-
7
-
-
0029050107
-
Sequence-specific inhibition of human immunodeficiency virus (HIV) reverse transcription by antisense oligonucleotides: Comparative study in cell-free assays and in HIV-infected cells
-
Bordier B., Perala-Heape M., Degols G., Lebleu B., Litvak S., Sarih-Cottin L. and Helene C. (1995) Sequence-specific inhibition of human immunodeficiency virus (HIV) reverse transcription by antisense oligonucleotides: comparative study in cell-free assays and in HIV-infected cells. Proc. Natl Acad. Sci. U.S.A. 92, 9383-9387.
-
(1995)
Proc. Natl Acad. Sci. U.S.A.
, vol.92
, pp. 9383-9387
-
-
Bordier, B.1
Perala-Heape, M.2
Degols, G.3
Lebleu, B.4
Litvak, S.5
Sarih-Cottin, L.6
Helene, C.7
-
8
-
-
0031000566
-
Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tertbutylbenzoyl)-2-hydroxy-1 -naphthaldehyde hydrazone
-
Borkow G., Fletcher R. S., Barnard J., Arion D., Motakis D., Dimitrienko G. I. and Parniak M. A. (1997) Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tertbutylbenzoyl)-2-hydroxy-1 -naphthaldehyde hydrazone. Biochemistry 36, 3179-3185.
-
(1997)
Biochemistry
, vol.36
, pp. 3179-3185
-
-
Borkow, G.1
Fletcher, R.S.2
Barnard, J.3
Arion, D.4
Motakis, D.5
Dimitrienko, G.I.6
Parniak, M.A.7
-
10
-
-
0026332351
-
Medicinal chemistry of antisense oligonucleotides - Future opportunities
-
Cook P. D. (1991) Medicinal chemistry of antisense oligonucleotides - future opportunities. Anti-Cancer Drug Design 6, 585-607.
-
(1991)
Anti-cancer Drug Design
, vol.6
, pp. 585-607
-
-
Cook, P.D.1
-
11
-
-
0026721173
-
Therapeutic applications of oligonucleotides
-
Crooke S. T. (1992) Therapeutic applications of oligonucleotides. Annu. Rev. Pharmacol Toxicol. 32, 329-376.
-
(1992)
Annu. Rev. Pharmacol Toxicol.
, vol.32
, pp. 329-376
-
-
Crooke, S.T.1
-
12
-
-
0025295567
-
An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis
-
Damha M. J., Giannaris P. A. and Zabarylo S. V. (1990) An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis. Nucleic Acids Res. 18, 813-3821.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 813-3821
-
-
Damha, M.J.1
Giannaris, P.A.2
Zabarylo, S.V.3
-
13
-
-
0003764447
-
Oligonucleotide synthesis
-
Edited by Agrawal S., The Humana Press, Totowas, NJ
-
Damha M. J. and Ogilvie K. K. (1993) Oligonucleotide synthesis. In Protocols for Oligonucleotides and Analogs: Synthesis and Properties, Methods in Molecular Biology (Edited by Agrawal S.), pp. 1-114. The Humana Press, Totowas, NJ.
-
(1993)
Protocols for Oligonucleotides and Analogs: Synthesis and Properties, Methods in Molecular Biology
, pp. 1-114
-
-
Damha, M.J.1
Ogilvie, K.K.2
-
14
-
-
0028235072
-
Antisense L/D-oligonucleotide chimeras: Nuclease stability, base-pairing properties, and activity at directing RNase H
-
Damha M. J., Giannaris P. A. and Marley P. (1994) Antisense L/D-oligonucleotide chimeras: nuclease stability, base-pairing properties, and activity at directing RNase H. Biochemistry 33, 7877-7885.
-
(1994)
Biochemistry
, vol.33
, pp. 7877-7885
-
-
Damha, M.J.1
Giannaris, P.A.2
Marley, P.3
-
15
-
-
0027447133
-
HIV-1-specific RT inhibitors: Highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase
-
De Clercq E. (1993) HIV-1-specific RT inhibitors: highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase. Med. Res. Rev. 13, 229-258.
-
(1993)
Med. Res. Rev.
, vol.13
, pp. 229-258
-
-
De Clercq, E.1
-
16
-
-
0028574120
-
Gene-targeted inhibition of transactivation of human immunodeficiency virus type-1 (HIV-l)-LTR by antisense oligonucleotides
-
Demirhan I., Hasselmayer O., Hofmann D., Chandra A., Svinarchuk F. P., Vlassov V. V., Engels J. and Chandra P. (1994) Gene-targeted inhibition of transactivation of human immunodeficiency virus type-1 (HIV-l)-LTR by antisense oligonucleotides. Virus Genes 9, 113-119.
-
(1994)
Virus Genes
, vol.9
, pp. 113-119
-
-
Demirhan, I.1
Hasselmayer, O.2
Hofmann, D.3
Chandra, A.4
Svinarchuk, F.P.5
Vlassov, V.V.6
Engels, J.7
Chandra, P.8
-
17
-
-
0028922944
-
Carboxanilide derivative nonnucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme
-
Fletcher R. S., Syed K., Mithani S., Dmitrienko G. I. and Parniak M. A. (1995) Carboxanilide derivative nonnucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme. Biochemistry 34, 4036-4042.
-
(1995)
Biochemistry
, vol.34
, pp. 4036-4042
-
-
Fletcher, R.S.1
Syed, K.2
Mithani, S.3
Dmitrienko, G.I.4
Parniak, M.A.5
-
18
-
-
0030087537
-
Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase
-
Fletcher R. S., Holleschak G., Nagy E., Arion D., Borkow G., Gu Z., Wainberg M. A. and Parniak M. A. (1996) Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase. Prot. Exp. Purif. 7, 27-32.
-
(1996)
Prot. Exp. Purif.
, vol.7
, pp. 27-32
-
-
Fletcher, R.S.1
Holleschak, G.2
Nagy, E.3
Arion, D.4
Borkow, G.5
Gu, Z.6
Wainberg, M.A.7
Parniak, M.A.8
-
20
-
-
0028352571
-
Hybridization properties of oligoarabinonucleosides
-
Giannaris P. A. and Damha M. J. (1993) Hybridization properties of oligoarabinonucleosides. Can. J. Chem. 72, 909-917.
-
(1993)
Can. J. Chem.
, vol.72
, pp. 909-917
-
-
Giannaris, P.A.1
Damha, M.J.2
-
21
-
-
0027445885
-
Oligoribonucleotides containing 2',5'-phosphodiester linkages exhibit binding selectivity for 3',5'-RNA versus 3',5'-ssDNA
-
Giannaris P. A. and Damha M. J. (1994) Oligoribonucleotides containing 2',5'-phosphodiester linkages exhibit binding selectivity for 3',5'-RNA versus 3',5'-ssDNA. Nucleic Acids Res. 21, 4742-4749.
-
(1994)
Nucleic Acids Res.
, vol.21
, pp. 4742-4749
-
-
Giannaris, P.A.1
Damha, M.J.2
-
22
-
-
0024999452
-
Retroviral reverse transcriptase: Synthesis, structure, and function
-
Goff S. (1990) Retroviral reverse transcriptase: synthesis, structure, and function. J. AIDS 3, 817-819.
-
(1990)
J. AIDS
, vol.3
, pp. 817-819
-
-
Goff, S.1
-
23
-
-
0028034266
-
The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2',3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro
-
Gu Z., Fletcher R. S., Arts E. J., Wainberg M. A. and Parniak M. A. (1994) The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2',3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro. J. Biol. Chem. 269, 28118-28122.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28118-28122
-
-
Gu, Z.1
Fletcher, R.S.2
Arts, E.J.3
Wainberg, M.A.4
Parniak, M.A.5
-
24
-
-
0027304997
-
Synthesis and binding properties of pyrimidine oligodeoxynucleoside analogues containing neutral phosphodiester replacements: The formacetal and 3'-thioaceltal internucleoside linkages
-
Jones R. J., Lin K. Y., Milligan J. F., Wadwani S. and Matteucci M. D. (1993) Synthesis and binding properties of pyrimidine oligodeoxynucleoside analogues containing neutral phosphodiester replacements: the formacetal and 3'-thioaceltal internucleoside linkages. J. Org. Chem. 58, 2983-2991.
-
(1993)
J. Org. Chem.
, vol.58
, pp. 2983-2991
-
-
Jones, R.J.1
Lin, K.Y.2
Milligan, J.F.3
Wadwani, S.4
Matteucci, M.D.5
-
25
-
-
0026565278
-
Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
-
Kellam P., Boucher C. A. B. and Larder B. A. (1992) Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Proc. Natl Acad. Sci. U.S.A. 89, 1934-1938.
-
(1992)
Proc. Natl Acad. Sci. U.S.A.
, vol.89
, pp. 1934-1938
-
-
Kellam, P.1
Boucher, C.A.B.2
Larder, B.A.3
-
26
-
-
0024310253
-
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
-
Larder B. A. and Kemp S. D. (1989) Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 246, 1155-1158.
-
(1989)
Science
, vol.246
, pp. 1155-1158
-
-
Larder, B.A.1
Kemp, S.D.2
-
27
-
-
33748246181
-
A sulfide-linked oligonucleotide analogue with selective hybridization properties
-
Meng B., Kawai S. H., Wang D., Just G., Gianarris P. A. and Damha M. J. (1993) A sulfide-linked oligonucleotide analogue with selective hybridization properties. Angew Chem. Int. Engl. 32, 729-731.
-
(1993)
Angew Chem. Int. Engl.
, vol.32
, pp. 729-731
-
-
Meng, B.1
Kawai, S.H.2
Wang, D.3
Just, G.4
Gianarris, P.A.5
Damha, M.J.6
-
28
-
-
0025679303
-
Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor
-
Merluzzi V. J., Hargrave K. D., Labadia M., Grozinger K., Skoog M. T., Wu J. C., Shih C.-K., Eckner K., Hattox S., Adams J., Rosehthal A. S., Faanes R., Eckner R. J., Koup R. A. and Sullivan J. L. (1990) Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor. Science 250, 1141-1413.
-
(1990)
Science
, vol.250
, pp. 1141-1413
-
-
Merluzzi, V.J.1
Hargrave, K.D.2
Labadia, M.3
Grozinger, K.4
Skoog, M.T.5
Wu, J.C.6
Shih, C.-K.7
Eckner, K.8
Hattox, S.9
Adams, J.10
Rosehthal, A.S.11
Faanes, R.12
Eckner, R.J.13
Koup, R.A.14
Sullivan, J.L.15
-
29
-
-
0025186450
-
Molecular targets for AIDS therapy
-
Mitsuya H., Yarchoan R. and Broder S. (1990) Molecular targets for AIDS therapy. Science 249, 1533-1544.
-
(1990)
Science
, vol.249
, pp. 1533-1544
-
-
Mitsuya, H.1
Yarchoan, R.2
Broder, S.3
-
30
-
-
0026734958
-
Anti-AIDS drug development: Challenges and strategies
-
Mohan P. (1992) Anti-AIDS drug development: challenges and strategies. Pharmaceut. Res. 9, 703-714.
-
(1992)
Pharmaceut. Res.
, vol.9
, pp. 703-714
-
-
Mohan, P.1
-
31
-
-
0024804759
-
Absorbance melting curves of RNA
-
Puglisi J. D. and Tinoco I. (1989) Absorbance melting curves of RNA. Meth. Enzymol. 180, 304-325.
-
(1989)
Meth. Enzymol.
, vol.180
, pp. 304-325
-
-
Puglisi, J.D.1
Tinoco, I.2
-
33
-
-
0026721099
-
Synthesis of thymidine dimers containing internuclcoside sulfonate and sulfonamide linkages
-
Reynolds R. C., Crooks P. A., Maddry J. A., Aktar M. S., Montogomery J. A. and Secrist J. A. (1992) Synthesis of thymidine dimers containing internuclcoside sulfonate and sulfonamide linkages. J. Org. Chem 57, 2983-2985.
-
(1992)
J. Org. Chem
, vol.57
, pp. 2983-2985
-
-
Reynolds, R.C.1
Crooks, P.A.2
Maddry, J.A.3
Aktar, M.S.4
Montogomery, J.A.5
Secrist, J.A.6
-
35
-
-
0025361871
-
Specific inhibition of human immunodeficiency virus type 1 replication by RNA transcribed in sense and antisense orientation from the 5'-leader/gag region
-
Sczakiel G., Pawlita M. and Kleinheinz A. (1990) Specific inhibition of human immunodeficiency virus type 1 replication by RNA transcribed in sense and antisense orientation from the 5'-leader/gag region. Biochem Biophys. Res. Commun. 169, 643-651.
-
(1990)
Biochem Biophys. Res. Commun.
, vol.169
, pp. 643-651
-
-
Sczakiel, G.1
Pawlita, M.2
Kleinheinz, A.3
-
36
-
-
11944267365
-
Antisense oligonucleotides: A new therapeutic principle
-
Uhlmann E. and Peyman A. (1990) Antisense oligonucleotides: a new therapeutic principle. Chem. Rev. 90, 543-584.
-
(1990)
Chem. Rev.
, vol.90
, pp. 543-584
-
-
Uhlmann, E.1
Peyman, A.2
-
37
-
-
0026683445
-
Oligonucleosides: Synthesis of a novel methyl-hydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences
-
Vasseur J.-J., Debart F., Sanghvi Y. S. and Cook P. D. (1992) Oligonucleosides: synthesis of a novel methyl-hydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences. J. Am. Chem. Soc. 114, 4006.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 4006
-
-
Vasseur, J.-J.1
Debart, F.2
Sanghvi, Y.S.3
Cook, P.D.4
-
38
-
-
0027246189
-
The polypurine tract, PPT, of HIV as target for antisense and triple-helix-forming oligonucleotides
-
Volkmann S., Dannull J. and Moeling K. (1993) The polypurine tract, PPT, of HIV as target for antisense and triple-helix-forming oligonucleotides. Biochimie 75, 71-78.
-
(1993)
Biochimie
, vol.75
, pp. 71-78
-
-
Volkmann, S.1
Dannull, J.2
Moeling, K.3
|