Pemphigus vulgaris autoantibody response is linked to HLA-DQB1*0503 in Pakistani patients

Human Immunology

Volumn 57, Issue 2, 1997, Pages 110-119

  Delgado, Julio C ^a   Hameed, Ahasan ^b   Yunis, Juan J ^c   Bhol, Kailash ^a,d   Rojas, Adriana I ^a,d   Rehman, Simeen B ^b   Khan, Ashfaq A ^b   Ahmad, Manzoor ^b   Alper, Chester A ^a   Ahmed, A Razzzaque ^a,d   Yunis, Edmond J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ARMY MEDICAL COLLEGE   (Pakistan)

^c UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; HLA TYPING; HUMAN; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; PEMPHIGUS VULGARIS; PRIORITY JOURNAL;

ALLELES; AUTOANTIBODIES; CHROMOSOME MAPPING; DISEASE SUSCEPTIBILITY; EUROPE; GENES, MHC CLASS II; GENETIC PREDISPOSITION TO DISEASE; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; IMMUNOBLOTTING; MOLECULAR STRUCTURE; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE PROBES; PAKISTAN; PEDIGREE; PEMPHIGUS; POLYMERASE CHAIN REACTION;

EID: 0031463420     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(97)00203-6     Document Type: Article

References (35)

1. Korman N. Pemphigus. J Am Acad Dermatol. 18:1988;1219.
2. Amagai M, Klaus-Kovtun V, Stanley JR. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell. 67:1991;869.
3. Stanley JR. Autoantibodies against adhesion molecules and structures in blistering skin diseases. J Exp Med. 181:1995;1.
4. Merlob P, Metzker A, Hazaz B, Rogovin H, Reisner SH. Neonatal pemphigus vulgaris. Pediatrics. 78:1986;1102.
5. Ahmed AR, Yunis EJ, Khatri K, Wagner R, Notani G, Awdeh Z, Alper CA. Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris. Proc Natl Acad Sci USA. 87:1990;7658.
6. Ahmed AR, Mohimen A, Yunis EJ, Mirza NM, Kumar V, Beutner EH, Alper CA. Linkage of pemphigus vulgaris antibody to the major histocompatibility complex in healthy relatives of patients. J Exp Med. 177:1993;419.
7. Ahmed AR, Wagner R, Khatri K, Notani G, Awdeh Z, Alper CA, Yunis EJ. Major histocompatibility complex haplotypes and class II genes in non-Jewish patients with pemphigus vulgaris. Proc Natl Acad Sci USA. 88:1991;5056.
8. Mobini N, Yunis EJ, Alper CA, Yunis JJ, Delgado JC, Yunis DE, Firooz A, Dowlati Y, Bahar K, Gregerson PK, Ahmed AR. Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris Possible common central Asian ancestral origin . Hum Immunol. 57:1997;62.
9. Niizeki H, Inoko H, Mizuki N, Inamoto N, Watanabe K, Hashimoto T, Nishikawa T. HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method. Tissue Antigens. 44:1994;248.
10. Lombardi ML, Mercuro O, Tecame G, Fusco C, Ruocco V, Salerno A, Pirozzi G, Manzo C. Molecular analysis of HLA DRB1 and DQB1 in Italian patients with pemphigus vulgaris. Tissue Antigens. 47:1996;228.
11. Carcassi C, Cottoni F, Floris L, Vacca A, Mulargia M, Arras M, Boero R, La Nasa G, Ledda A, Pizzati A, Cerimele D, Contu L. HLA haplotypes and class II molecular alleles in Sardinian and Italian patients with pemphigus vulgaris. Tissue Antigens. 48:1996;662.
12. Delgado JC, Yunis DE, Bozon MV, Salazar M, Deulofeut R, Turbay D, Mehra NK, Pasricha JS, Raval RS, Patel H, Shah BK, Bhol K, Alper CA, Ahmed AR, Yunis EJ. MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India. Tissue Antigens. 48:1996;668.
13. Beutner EH, Jordon RE, Chorzelski TP. The immunopathology of pemphigus and bullous pemphigoid 1968 . J Invest Dermatol. 92:1989;166S.
14. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16:1988;1215.
15. Salazar M, Yunis JJ, Delgado MB, Bing D, Yunis EJ. HLA-DQB1 allele typing by a new PCR-RFLP method Correlation with a PCR-SSO method . Tissue Antigens. 40:1992;116.
16. Yunis JJ, Delgado MB, Lee-Lewandroski E, Yunis EJ, Bing DH. Rapid identification of HLA-DRw53-positive samples by a generic DRB-PCR amplification without further analysis. Tissue Antigens. 40:1992;41.
17. Yunis JJ, Salazar M, Delgado MB, Alper CA, Bing DH, Yunis EJ. HLA-DQA1, DQB1 and DPB1 alleles on HLA-DQ2- and DQ9-carrying extended haplotypes. Tissue Antigens. 41:1993;37.
18. Hashimoto T, Ogawa MM, Konohana A, Nishikawa T. Detection of pemphigus vulgaris and pemphigus foliaceus antigens by immunoblot analysis using different antigen sources. J Invest Dermatol. 94:1990;327.
19. Mohimen A, Ahmed AR. Comparison of an indirect immunofluorescence assay and a modified sensitive immunoblot assay for the study of the autoantibody in pemphigus vulgaris. Arch Dermatol Res. 287:1995;202.
20. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680.
21. Mirza NM, Mohimen A, Ahmed AR. Detection of pemphigus vulgaris antigen on COLO and SCaBER tumor cell lines by the immunoblot technique. Arch Dermatol Res. 282:1990;418.
22. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets Procedure and some applications . Proc Natl Acad Sci U S A. 76:1979;4350.
23. Granja, CB, Salazar M, Yunis EJ: Population genetics and HLA polymorphism. In Transplantation Biology: Cellular and Molecular Aspects. Tilney NL, Strom TB, editors. Lippincott-Raven, Philadelphia. 311, 1996.
24. Morton NE. Sequential tests for the detection of linkage. Am J Hum Gen. 26:1955;588.
25. Bhol K, Yunis J, Ahmed AR. Pemphigus vulgaris in distant relatives of two families Association with major histocompatibility complex class II genes . Clin Exp Dermatol. 21:1996;100.
26. Scharf SJ, Freidmann A, Steinman L, Brautbar C, Erlich HA. Specific HLA-DQB and HLA-DRB1 alleles confer susceptibility to pemphigus vulgaris. Proc Natl Acad Sci USA. 86:1989;6215.
27. Sinha AA, Brautbar C, Szafer F, Friedman A, Tzfoni E, Todd JA, Steinman L, McDevitt HO. A newly characterized HLA DQ beta allele associated with pemphigus vulgaris. Science. 239:1988;1026.
28. Bhol K, Natarajan K, Nagarwalla N, Mohimen A, Aoki V, Ahmed AR. Correlation of peptide specificity and IgG subclass with pathogenic and nonpathogenic autoantibodies in pemphigus vulgaris A model for autoimmunity . Proc Natl Acad Sci USA. 92:1995;5239.
29. Wucherpfennig KW, Yu B, Bhol K, Monos DS, Argyris E, Karr RW, Ahmed AR, Strominger JL. Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity Charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris . Proc Natl Acad Sci USA. 92:1995;11935.
30. Wucherpfennig KW, Strominger JL. Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules A mechanism for MHC-linked susceptibility to human autoimmune diseases . J Exp Med. 181:1995;1597.
31. Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature. 368:1994;215.
32. Hammer J, Gallazzi F, Bono E, Karr RW, Guenot J, Valsasnini P, Nagy ZA, Sinigaglia F. Peptide binding specificity of HLA-DR4 molecules Correlation with rheumatoid arthritis association . J Exp Med. 181:1995;1847.
33. Zerva L, Cizman B, Mehra NK, Alahari SK, Murali R, Zmijewski CM, Kamoun M, Monos DS. Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB1 alleles is associated with susceptibility to tuberculoid leprosy. J Exp Med. 183:1996;829.
34. Todd JA, Bell JI, McDevitt HO. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature. 329:1987;599.
35. Brandsen R, Frusic-Zlotkin M, Lyubimov H, Yunes F, Michel B, Tamir A, Milner Y, Brenner S. Circulating pemphigus IgG in families of patients with pemphigus Comparison of indirect immunofluorescence, direct immunofluorescence, and immunoblotting . J Am Acad Dermatol. 36:1997;44.