Specific adrenomedullin binding sites in the human brain

Peptides

Volumn 18, Issue 8, 1997, Pages 1125-1129

  Sone, Masahiko ^a   Takahashi, Kazuhiro ^b   Satoh, Fumitoshi ^b   Murakami, Osamu ^b   Totsune, Kazuhito ^b   Ohneda, Makoto ^b   Sasano, Hironobu ^b   Ito, Hisao ^a   Mouri, Toraichi ^c  

^a National Hospital Organization Iwate Hospital   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Division of Neuroendocrinology   (Japan)

Author keywords

Adrenomedullin; Calcitonin gene related peptide; Human brain; Receptor

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; NEUROTRANSMITTER; RADIOLIGAND; RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BINDING SITE; BRAIN; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; DISSOCIATION CONSTANT; FEMALE; HUMAN; HUMAN TISSUE; HYPOTHALAMUS; LIGAND BINDING; MALE; MEDULLA OBLONGATA; PONS; PRIORITY JOURNAL; RECEPTOR BINDING; SCATCHARD PLOT; THALAMUS;

ADRENOMEDULLIN; BRAIN; CALCITONIN GENE-RELATED PEPTIDE; HUMANS; MEMBRANE PROTEINS; PEPTIDES; RADIOLIGAND ASSAY; RECEPTORS, PEPTIDE;

EID: 0031458298     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(97)00143-5     Document Type: Article

References (36)

1. Champion H. C., Santiago J. A., Murphy W. A., Coy D. H., Kadowitz P. J. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am. J. Physiol. 272:1997;R234-R242.
2. Cheng D. Y., DeWitt B. J., Wegmann M. J., Coy D. H., Bitar K., Murphy W. A., Kadowitz P. J. Synthetic human adrenomedullin and ADM 15-52 have potent short-lasting vasodilator activity in the pulmonary vascular bed of the cat. Life Sci. 55:1994;L251-L256.
3. Eguchi S., Hirata Y. Kano, H.; et al . Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells. FEBS Lett. 340:1994;226-230.
4. Eguchi S., Hirata Y., Iwasaki H., et al. Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells. Endocrinology. 135:1994;2454-2458.
5. 1 receptors. Life Sci. 56:1995;L19-L25.
6. Gardiner S. M., Kemp P. A., March J. E., Bennett T. Regional haemodynamic effects of human and rat adrenomedullin in conscious rats. Br. J. Pharmacol. 114:1995;584-591.
7. 13-52 with calcitonin gene-related peptide receptors in the microvasculature of the rat and hamster. Br. J. Pharamacol. 114:1995;592-597.
8. Hirata Y., Hayakawa H., Suzuki Y., et al. Mechanism of adrenomedullin-induced vasodilatation in the rat kidney. Hypertension. 25:1995;790-795.
9. Hunter W. M., Greenwood F. C. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature. 194:1962;495-496.
10. Ishizaka Y., Ishizaka Y., Tanaka M., et al. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 200:1994;642-646.
11. Kapas S., Catt K. J., Clark A. J. L. Cloning and expression of cDNA encoding a rat adrenomedullin receptor. J. Biol. Chem. 270:1995;25344-25347.
12. Kitamura K., Kangawa K., Kawamoto M., et al. Adrenomedullin A novel hypotensive peptide isolated from human pheochromocytoma . Biochem. Biophys. Res. Commun. 192:1993;553-560.
13. Kitamura K., Sakata J., Kangawa K., Kojima M., Matsuo H., Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem. Biophys. Res. Commun. 194:1993;720-725.
14. Kitamura K., Ichiki Y., Tanaka M., et al. Immunoreactive adrenomedullin in human plasma. FEBS Lett. 341:1994;288-290.
15. Miller M. J., Martinez A., Unsworth E. J., et al. Adrenomedullin expression in human tumor cell lines. J. Biol. Chem. 271:1996;23345-23351.
16. Murphy T. C., Samson W. K. The novel vasoactive hormone, adrenomedullin, inhibits water drinking in the rat. Endocrinology. 136:1995;2459-2463.
17. Nandha K. A., Taylor G. M., Smith D. M., et al. Specific adrenomedullin binding sites and hypotension in the rat systemic vascular bed. Regul. Pept. 62:1996;145-151.
18. Nossaman B. D., Feng C. J., Cheng D. Y., Deewitt B. J., Coy D. H., Murphy W. A., Kadowitz P. J. Comparative effects of adrenomedullin, an adrenomedullin analog, and CGRP in the pulmonary vascular bed of the cat and rat. Life Sci. 56:1995;L63-L66.
19. Nuki C., Kawasaki H., Kitamura K., et al. Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds. Biochem. Biophys. Res. Commun. 196:1993;245-251.
20. Owji A. A., Smith D. M., Coppock H. A., et al. An abundant and specific binding site for the novel vasodilator adrenomedullin in the rat. Endocrinology. 136:1995;2127-2134.
21. 2 receptor subtypes. Ann. NY Acad. Sci. 657:1992;88-105.
22. Samson W. K., Murphy T., Schell D. A. A novel vasoactive peptide, adrenomedullin, inhibits pituitary adrenocorticotropin release. Endocrinology. 136:1995;2349-2352.
23. Satoh F., Takahashi K., Murakami O., et al. Adrenomedullin in human brain, adrenal glands and tumor tissues of pheochromocytoma, ganglioneuroblastoma and neuroblastoma. J. Clin. Endocrinol. Metab. 80:1995;1750-1752.
24. Satoh F., Takahashi K., Murakami O., et al. Immunocytochemical localization of adrenomedullin-like immunoreactivity in the human hypothalamus and the adrenal gland. Neurosci. Lett. 203:1996;207-210.
25. Sone M., Smith D. M., Ghatei M. A., et al. Pituitary adenylate cyclase-activating polypeptide (PACAP) vasoactive intestinal peptide (VIP) receptor subtypes in rat tissues Investigation of receptor binding, a novel VIP receptor antagonist and chemical cross-linking Biomed . Res. 15:1994;145-153.
26. Takahashi H., Watanabe T. X., Nishimura M., et al. Centrally induced vasopressor and sympathetic responses to a novel endogenous peptide, adrenomedullin, in anesthetized rats. Am. J. Hypertens. 7:1994;478-482.
27. Takahashi K., Mouri T., Sone M., et al. Calcitonin gene-related peptide in the human hypothalamus. Endocrinol. Jpn. 36:1989;409-415.
28. Takahashi K., Sone M., Satoh F., Murakami O., Totsune K., Tanji H., Sato N., Ito H., Mouri T. Presence of adrenomedullin-like immunoreactivity in the human cerebrospinal fluid. Peptides. 118:1997;459-461.
29. Takahashi K., Satoh F., Hara E., et al. Production and secretion of adrenomedullin by cultured choroid plexus carcinoma cells. J. Neurochem. 68:1997;726-731.
30. Takahashi K., Satoh F., Sone M., Murakami O., Sasano H., Mouri T., Shibahara S. Expression of adrenomedullin mRNA in the human brain and pituitary. Peptides. 18:1997;1051-1053.
31. Taylor G. M., Meeran K., O'Shea D., Smith D. M., Ghatei M. A., Bloom S. R. Adrenomedullin inhibits feeding in the rat by a mechanism involving calcitonin gene-related peptide receptors. Endocrinology. 137:1996;3260-3264.
32. Tschopp F. A., Henke H., Petermann J.B., et al. Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary. Proc. Natl. Acad. Sci. USA. 82:1985;248-252.
33. Ueta Y., Kitamura K., Isse T., et al. Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat. Neurosci. Lett. 202:1995;37-40.
34. Wang X., Yue T.-L., Barone F. C., et al. Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal ischemic damage. Proc. Natl. Acad. Sci. USA. 92:1995;11480-11484.
35. Washimine H., Asada Y., Kitamura K., et al. Immunohistochemical identification of adrenomedullin in human, rat, and porcine tissue. Histochemistry. 103:1995;251-254.
36. Yokoi H., Arima H., Murase T., Kondo K., Iwasaki Y., Oiso Y. Intracerebroventricular injection of adrenomedullin inhibits vasopressin release in conscious rats. Neurosci. Lett. 216:1996;65-67.