Selective brain to blood efflux transport of para-aminohippuric acid across the blood-brain barrier: In vivo evidence by use of the brain efflux index method

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 3, 1997, Pages 1018-1025

  Kakee, Atsuyuki ^a   Terasaki, Tetsuya ^b   Sugiyama, Yuichi ^c  

^a JAPAN TOBACCO INC   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; CARRIER PROTEIN; INULIN; TRITIUM;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID; DRUG CLEARANCE; DRUG ELIMINATION; DRUG METABOLISM; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG UPTAKE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; MALE; METABOLIC CLEARANCE RATE; MICROINJECTIONS; P-AMINOHIPPURIC ACID; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031456590     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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