Patients treated with interferon-α, interferon-β, and interleukin-2 have a different thyroid autoantibody pattern than patients suffering from endogenous autoimmune thyroid disease

Thyroid

Volumn 7, Issue 6, 1997, Pages 837-842

  Schuppert, Frank ^a   Rambusch, Erwin ^a   Kirchner, Hartmut ^b   Atzpodien, Jens ^a   Kohn, Leonard D ^c   Von Zur Mühlen, Alexander ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Hospital Siloah   (Germany)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; BETA INTERFERON; INTERFERON BETA SERINE; INTERLEUKIN 2; RECOMBINANT ALPHA2B INTERFERON; RECOMBINANT INTERLEUKIN 2; THYROGLOBULIN ANTIBODY; THYROID ANTIBODY;

ADULT; AGED; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; AUTOIMMUNE DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; HASHIMOTO DISEASE; HUMAN; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; THYROID DISEASE; THYROIDITIS; VIRUS HEPATITIS;

EID: 0031449007     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.1997.7.837     Document Type: Article

References (26)

1. McLachlan SM, Rapoport B 1996 Genetic factors in thyroid disease. In: Braverman LE, Utiger RD, (eds). The Thyroid. Lippincott-Raven, Philadelphia, p 483-496.
2. Weetman AP, McGregor AM 1994 Autoimmune thyroid disease: Further developments in our understanding. Endocr Rev 15:788-830.
3. Shimojo N, Kohno Y, Yamaguchi K, Kikuoka S, Hoshioka A, Niimi H, Hirai A, Tamura Y, Saito Y, Kohn LD, Tahara K 1996 Induction of Graves-like disease in mice by immunization with fibroblasts transfected with thyrotropin receptor and a class II molecule. Proc Natl Acad Sci USA 93:11074-11079.
4. Hanafusa T, Pujol Borrell R, Chiovato L, Russell RC, Doniach D, Bottazzo GF 1983 Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: Relevance for autoimmunity. Lancet 2:1111-1115.
5. Todd I, Londei M, Pujol Borrell R, Mirakian R, Feldmann M, Bottazzo GF 1986 HLA-D/DR expression on epithelial cells: The finger on the trigger? Ann NY Acad Sci 475:241-250.
6. Kohn LD, Giuliani C, Montani V, Napolitano G, Ohmori M, Ohta M, Saji M, Schuppen F, Shong M, Suzuki K, Shin-Ichi T, Yano K, Singer DS 1995 Antireceptor immunity. In: Rayner D, Champion BR (eds) Thyroid Autoimmunity. RG Landes Company, Austin, pp 115-170.
7. Schuppert F, Taniguchi SI, Schröder S, Dralle H, Von zur Mühlen A, Kohn LD 1996 In vivo and in vitro evidence for iodide regulation of MHC class I and class II expression in Graves disease. J Clin Endocrinol Metab 81:3622-3628.
8. Saji M, Moriarty J, Ban T, Singer DS, Kohn LD 1992 Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as interferon. J Clin Endocrinol Metab 75:871-878.
9. Todd I, Pujol Borrell R, Hammond LJ, Bottazzo GF, Feldmann M 1985 Interferon-gamma induces HLA-DR expression by thyroid epithelium. Clin Exp Immunol 61:265-273.
10. Zakarija M, Hornicek FJ, Levis S, McKenzie JM 1988 Effects of gamma-interferon and tumor necrosis factor a on thyroid cells: Induction of class II antigen and inhibition of growth stimulation. Mol Cell Endocrinol 58:129-136.
11. Migita K, Eguchi K, Otsubo T, Kawakami A, Nakao H, Ueki Y, Shimomura C, Kurata A, Fukuda T, Matsunaga M, Ishikawa N, Ito K, Nagataki S 1990 Cytokine regulation of HLA on thyroid epithelial cells. Clin Exp Immunol 82:548-552.
12. Burman P, Totterman TH, Oberg K, Karlsson FA 1986 Thyroid autoimmunity in patients on long term therapy with leukocyte-derived interferon. J Clin Endocrinol Metab 63:1086-1090.
13. Pichert G, Jost LM, Fierz W, Stahel RA 1991 Clinical and immune modulatory effects of alternative weekly interleukin-2 and Interferon alfa-2a in patients with advanced renal cell carcinoma and melanoma. Br J Cancer 63:287-292.
14. Mayet W-J, Hess G, Gerken G, Rossol S, Voth R, Manns M, Meyer zum Büschenfelde K-H 1989 Treatment of chronic type B hepatitis with recombinant alpha-interferon induces autoantibodies not specific for autoimmune chronic hepatitis. Hepatology 10:24-28.
15. Watanabe U, Hashimoto E, Hisamitsu T, Obata H, Hayashi N 1994 The risk factor for development of thyroid disease during interferon-alpha therapy for chronic hepatitis C. Am J Gastroenterol 89:399-403.
16. Schuppert F, Müller-Kunert E, Stöcker W, Bokemeyer C, Schmoll H-J, Von Zur Mühlen A, Rambusch E 1996 Cytokine therapy and the endocrine system: Is it necessary to monitor more than the thyroid gland? Results of a study on 61 patients. Med Klin 91:59-65.
17. Baudin E, Marcellin P, Pouteau M, Colas-Linhart N, Le Floch J-P, Lemmonier C, Benhamou J-P, Bok B 1993 Reversibility of thyroid dysfunction induced by recombinant alpha interferon in chronic hepatitis C. Clin Endocrinol (Oxf) 39:657-661.
18. Marazuela M, Garcia Buey L, Gonzalez Fernandez B, Garcia Monzon C, Arranz A, Borque MJ, Moreno Otero R 1996 Thyroid autoimmune disorders in patients with chronic hepatitis C before and during interferon-alpha therapy. Clin Endocrinol (Oxf) 44:635-642.
19. Gisslinger H, Gilly B, Wolosrczuk W, Mayr WR, Havelec L, Linkesch W, Weissel M 1992 Thyroid autoimmunity and hypothyroidism during long-term treatment with recombinant interferon-alpha. Clin Exp Immunol 90:363-367.
20. Ashizawa K, Yamashita S, Nagayama Y, Kimura H, Hirayu H, Izumi M, Nagataki S 1989 Interferon-gamma inhibits thyrotropin-induced thyroidal peroxidase gene expression in cultured human thyrocytes. J Clin Endocrinol Metab 69:475-477.
21. Kung AWC, Ma L, Lau KS 1992 The role of interferon-gamma in lymphocytic thyroiditis: Its functional and pathological effect on human thyrocytes in culture. Clin Exp Immunol 87:261-265.
22. Nishikawa T, Yamashita S, Namba H, Usa T, Tominaga T, Kimura H, Izumi M, Nagataki S 1993 Interferon-gamma inhibition of human thyrotropin receptor gene expression. J Clin Endocrinol Metab 77:1084-1089.
23. Chiovato L, Lapi P, Mariotti S, Del Prete G, De Carli M, Pinchera A 1994 Simultaneous expression of thyroid peroxidase and human leukocyte antigen-DR by human thyroid cells: Modulation by thyrotropin, thyroid-stimulating antibody, and interferon-gamma. J Clin Endocrinol Metab 79:653-656.
24. Watson PF, Pickerill AP, Davies R, Weetman AP 1994 Analysis of cytokine gene expression in Graves' disease and multinodular goiter. J Clin Endocrinol Metab 79:355-360.
25. Paschke R, Schuppert F, Taton M, Velu T 1994 Intrathyroidal cytokine gene expression profiles in autoimmune thyroiditis. J Endocrinol 141:309-315.
26. Schuppert F, Hiller WFA, Weinland G, Hoang-Vu C, Von zur Mühlen A, Kohn LD 1996 Iodide, cytokines and TSH receptor expression in Graves' disease. Exp Clin Endocrinol Diabetes 104(Suppl 4):68-74.