메뉴 건너뛰기




Volumn 64, Issue 11, 1997, Pages 1525-1531

Combination therapy with cyclosporine and interleukin-4 or interleukin- 10 prolongs survival of syngeneic pancreatic islet grafts in nonobese diabetic mice: Islet graft survival does not correlate with mRNA levels of type 1 or type 2 cytokines, or transforming growth factor-β in the islet grafts

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031443261     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199712150-00004     Document Type: Article
Times cited : (19)

References (20)
  • 3
    • 0026646694 scopus 로고
    • The murine autoimmune diabetes model: NOD mouse and related strains
    • Dixon FJ, ed. New York: Academic Press
    • Kikutani H, Makino S. The murine autoimmune diabetes model: NOD mouse and related strains. In: Dixon FJ, ed. Advances in immunology. New York: Academic Press, 1992: 285.
    • (1992) Advances in Immunology , pp. 285
    • Kikutani, H.1    Makino, S.2
  • 4
    • 0028354067 scopus 로고
    • Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: Therapeutic intervention by immunostimulation?
    • Rabinovitch A. Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: therapeutic intervention by immunostimulation? Diabetes 1994; 43: 613.
    • (1994) Diabetes , vol.43 , pp. 613
    • Rabinovitch, A.1
  • 6
    • 0028882673 scopus 로고
    • Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-β, and prostaglandin E
    • Hancock WW, Polanski M, Zhang J, Blogg N, Weiner HL. Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-β, and prostaglandin E. Am J Pathol 1995; 147: 1193.
    • (1995) Am J Pathol , vol.147 , pp. 1193
    • Hancock, W.W.1    Polanski, M.2    Zhang, J.3    Blogg, N.4    Weiner, H.L.5
  • 7
    • 0029091751 scopus 로고
    • Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice
    • Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF, Rajotte RV. Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Transplantation 1995; 60: 368.
    • (1995) Transplantation , vol.60 , pp. 368
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4    Power, R.F.5    Rajotte, R.V.6
  • 8
    • 0029810079 scopus 로고    scopus 로고
    • Primary nonfunction of islet grafts in autoimmune diabetic nonobese diabetic mice is prevented by treatment with interleukin-4 and interleukin-10
    • Faust A, Rothe H, Schade U, Lampeter E, Kolb H. Primary nonfunction of islet grafts in autoimmune diabetic nonobese diabetic mice is prevented by treatment with interleukin-4 and interleukin-10. Transplantation 1996; 62: 648.
    • (1996) Transplantation , vol.62 , pp. 648
    • Faust, A.1    Rothe, H.2    Schade, U.3    Lampeter, E.4    Kolb, H.5
  • 9
    • 0028358905 scopus 로고
    • Quantitative comparison of rapamycin and cyclosporine effects on cytokine gene expression studied by reverse transcriptase-competitive polymerase chain reaction
    • Zheng XX, Strom TB, Steele AW. Quantitative comparison of rapamycin and cyclosporine effects on cytokine gene expression studied by reverse transcriptase-competitive polymerase chain reaction. Transplantation 1994; 58: 87.
    • (1994) Transplantation , vol.58 , pp. 87
    • Zheng, X.X.1    Strom, T.B.2    Steele, A.W.3
  • 10
    • 0026502893 scopus 로고
    • Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy
    • Wang T, Singh B, Warnock GL, Rajotte RV. Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy. Diabetes 1992; 41: 114.
    • (1992) Diabetes , vol.41 , pp. 114
    • Wang, T.1    Singh, B.2    Warnock, G.L.3    Rajotte, R.V.4
  • 11
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter KT. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294.
    • (1979) Biochemistry , vol.18 , pp. 5294
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, K.T.4
  • 12
    • 0028989087 scopus 로고
    • IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice
    • Rabinovitch A, Suarez-Pinzon WL, Sorensen O, Bleackley RC, Power RF. IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice. J Immunol 1994; 154: 4874.
    • (1994) J Immunol , vol.154 , pp. 4874
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4    Power, R.F.5
  • 13
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy MK, Torrance DS, Picha KS, Mohler KM. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 1992; 149: 2496.
    • (1992) J Immunol , vol.149 , pp. 2496
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 14
    • 0025981388 scopus 로고
    • Essential role for interferon-γ and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice
    • Campbell IL, Kay TWH, Oxbrow L, Harrison LC. Essential role for interferon-γ and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice. J Clin Invest 1991; 87: 739.
    • (1991) J Clin Invest , vol.87 , pp. 739
    • Campbell, I.L.1    Kay, T.W.H.2    Oxbrow, L.3    Harrison, L.C.4
  • 15
    • 0027291701 scopus 로고
    • Altered cytokine activity in adjuvant inhibition of autoimmune diabetes
    • Shehadeh N, LaRosa F, Lafferty KJ. Altered cytokine activity in adjuvant inhibition of autoimmune diabetes. J Autoimmun 1993; 6: 291.
    • (1993) J Autoimmun , vol.6 , pp. 291
    • Shehadeh, N.1    LaRosa, F.2    Lafferty, K.J.3
  • 16
    • 0027970206 scopus 로고
    • Cyclophosphamide treatment of female non-obese diabetic mice causes enhanced expression of inducible nitric oxide synthase and interferon-γ, but not of interleukin-4
    • Rothe H, Faust A, Schade U, et al. Cyclophosphamide treatment of female non-obese diabetic mice causes enhanced expression of inducible nitric oxide synthase and interferon-γ, but not of interleukin-4. Diabetologia 1994; 37: 1154.
    • (1994) Diabetologia , vol.37 , pp. 1154
    • Rothe, H.1    Faust, A.2    Schade, U.3
  • 17
    • 0028095152 scopus 로고
    • Analysis of cytokine mRNA expression in syngeneic islet grafts of NOD mice: Interleukin 2 and interferon gamma mRNA expression correlate with graft rejection and interleukin 10 with graft survival
    • Rabinovitch A, Sorensen O, Suarez-Pinzon WL, Power RF, Rajotte RV, Bleackley RC. Analysis of cytokine mRNA expression in syngeneic islet grafts of NOD mice: interleukin 2 and interferon gamma mRNA expression correlate with graft rejection and interleukin 10 with graft survival. Diabetologia 1994; 37: 833.
    • (1994) Diabetologia , vol.37 , pp. 833
    • Rabinovitch, A.1    Sorensen, O.2    Suarez-Pinzon, W.L.3    Power, R.F.4    Rajotte, R.V.5    Bleackley, R.C.6
  • 18
    • 0028861576 scopus 로고
    • Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-γ transcription
    • Muir A, Peck A, Clare-Salzler M, et al. Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-γ transcription. J Clin Invest 1995; 95: 628.
    • (1995) J Clin Invest , vol.95 , pp. 628
    • Muir, A.1    Peck, A.2    Clare-Salzler, M.3
  • 20
    • 0030032393 scopus 로고    scopus 로고
    • Interleukin-12 gene expression is associated with rapid development of diabetes mellitus in non-obese diabetic mice
    • Rothe H, Burkart V, Faust A, Kolb H. Interleukin-12 gene expression is associated with rapid development of diabetes mellitus in non-obese diabetic mice. Diabetologia 1996; 39: 119.
    • (1996) Diabetologia , vol.39 , pp. 119
    • Rothe, H.1    Burkart, V.2    Faust, A.3    Kolb, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.